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Transitions among Mariana-,Japan-,Cordillera-and Alaska-type are systems and their final juxtapositions leading to accretionary and collisional orogenesis

Transitions among Mariana-,Japan-,Cordillera-and Alaska-type...

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中国科学院地质与地球物理研究所第十届(2010年度)学术年会

作者： WENJIAO XIAO~(1*),CHUNMING HAN~1,CHAO YUAN~2,MIN SUN~3, GUOCHUN ZHAO~3 & YEHUA SHAN~2 1 State Key Laboratory of Lithospheric Evolution,Institute of Geology and Geophysics, chinese Academy of Sciences,Beijing 100029,China 2 Guangzhou Institute of Geochemistry,chinese Academy of Sciences,Guangzhou 510640,China 3 Department of Earth Sciences,The University of Hong Kong,Hong Kong,China

’Arc system’ is used here as a collective term for a variety of arcs that occur along continental margins or in oceanic plates;it includes associated units from adjacent *** major arc systems(Mariana-,Japan-,Cordillera-and Alaska-type)can be distinguished along the Circum-Pacific *** Japan-type arc systems in ancient orogens(*** Altaids) may have been largely regarded as microcontinents because they have so-called Precambrian basement. Often the Cordillera-type arc systems can be very complicated,and if they are rifted away from the host continent they become more difficult to *** these arc systems interact mutually and with continental marginal sequences,leading to complicated accretionary and colhsional *** alternation between Western Pacific archipelagos and the Eastern Pacific active margin is the stereotype of accretionary and colhsional *** importantly, these four main types of arc systems can be juxtaposed into a final orogenic collage, which is another main expression of accretionary *** some parts of accretionary and colhsional orogens can be terminated by attachment of a continent-size craton such as Tarim or even India,and even so the accretionary and colhsional processes may continue elsewhere along *** significance of the interactions among these arc systems and their final juxtaposition has not been fully appreciated in ancient *** Altaids together with the Circum-Pacific orogens offers a good opportunity to study such accretionary-collisional orogenesis.

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Genome editing for the treatment of tumorigenic viral infectionsand virus-related carcinomas

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Frontiers of Medicine 2018年第5期12卷 497-508页

作者： Lan Yu Xun Tian Chun Gao Ping Wu Liming Wang Bei Feng Xiaomin Li Hui Wang Ding Ma Zheng Hu Cancer Biology Research Center (Key Laboratory of the Ministry of Education) Tongji Hospital Tong/i Medical College HuazhongUniversity of Science and Technology Wuhan 430030 China Department of Obstetrics and Gynecology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Department of Gynecological Oncology First AffiliatedHospital of Sun Yat-sen University Guangzhou 510080 China Department of Gynecology and Obstetrics First Affiliated Hospital ofGuangzhou Medical University Guangzhou 510120 China

Viral infections cause at least 10%-15% of all human carcinomas. Over the last century, the elucidation of viral oncogenic roles in many cancer types has provided fundamental knowledge on carcinogenetic mechanisms and established a basis for the early intervention of virus-related cancers. Meanwhile, rapidly evolving genome-editing techniques targeting viral DNA/RNA have emerged as novel therapeutic strategies for treating virus-related carcinogenesis and have begun showing promising results. This review discusses the recent advances of genome-editing tools for treating tumorigenic viruses and their corresponding cancers, the challenges that must be overcome before clinically applying such genome-editing technologies, and more importantly, the potential solutions to these challenges.

关键词： delivery method genome-editing tools off-target effect tumorigenic virus virus-related carcinoma

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Geochronological and geochemical study of gneiss-schist complexes and associated granitoids,Beishan Orogen,southern Altaids

Geochronological and geochemical study of gneiss-schist comp...

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中国科学院地质与地球物理研究所2013年度（第13届）学术年会

作者： Dongfang Song Wenjiao Xiao Chunming Han Zhonghua Tian State Key Laboratory of Lithospheric Evolution Chinese Academy of Sciences Graduate University of chinese Academy of Sciences State Key Laboratory of Lithospheric Evolution chinese Academy of Sciences Xinjiang Researeh Centre for Mineral Resources

The tectonic nature of metamorphic terranes and their role in orogenesis are *** we present new U-Pb ages and geochemical data for widespread metamorphic rocks and associated granitoids from Northwest *** from the metamorphic complexes have crystallization ages of～457,～452,and～526 *** paragneiss(schist)has a maximum depositional age of 312±7 *** foliated granites were emplaced at～450,～349,and～410 Ma,and all lack inherited Precambrian *** metamorphic terranes may have undergone multiple petrotectonic events as revealed by the metamorphic *** the orthogneisses and granitoids show enrichment in large ion lithophile elements(LILEs)and light rare Earth elements(LREEs),and depletion in high field strength elements(HFSEs),which indicate that they formed in a subduction-generated accretionary arc *** study demonstrates that the metamorphic terranes in the Beishan area, originally considered as Precambrian basement with suspected Neoarchaean to Palaeoproterozoic ages,are actually parts of early Palaeozoic *** protoliths were probably metamorphosed arc plutonic and sedimentary *** with other studies,we speculate that the Beishan Orogen formed by progressive arc accretion during the latest Neoproterozoic to early Palaeozoic *** new interpretation has implications for other high-grade metamorphic terranes within orogens that have been assumed to represent ancient or pre-existing micro-continental *** so,the importance of collision as a mechanism of mountain building has been overestimated,and the accretionary process as a mechanism of continental growth has been underestimated.

关键词： Southern Altaids Beishan Orogen metamorphic complex granitoids early Palaeozoic arc accretion

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New age determination of the Cenozoic Lunpola basin,central Tibet

New age determination of the Cenozoic Lunpola basin,central ...

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中国科学院地质与地球物理研究所2012年度（第12届）学术年会

作者： HUAIYU HE JIMIN SUN QIULI LI RIXIANG ZHU Key Laboratory of the Earth's Deep Interior Institute of Geology and GeophysicsChinese Academy of Sciences State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of Sciences

Knowing when the Tibetan Plateau reached its present elevation is important for understanding the uplift history of ***,Rowley & Currie(2006) suggested that central Tibet exceeded 4000 in from 3 5 Ma to the Pliocene using the oxygen-isotope composition of calcareous minerals in Lunpola basin ***,they adopted a poor age assignment for the Dingqing Formation in the Lunpola basin based on previous microfossil *** this study, we present SIMS U-Pb zircon dates from a bentonite layer intercalated within the middle to lower Dingqing Formation. Twenty-six measurements yield a highly reliable U-Pb age of 23.5±0.2 Ma(2a,MSWD = 1.1),suggesting that the deposition age of the Dingqing Formation is late Oligocene to early Miocene,much older than the Miocene Pliocene age used by Rowley & Currie(2006).This age robustly constrains the age of Ccnozoic sedimentary strata in central Tibet,and hence provides an important basis for estimating the palaeoelevation in the high Tibet during the geological past.

关键词： SIMS U-Pb zircon geochronology Lunpola basin bentonite central Tibet

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Tectonic implications of Re-Os dating of molybdenum deposits in the Tianshan–Xingmeng Orogenic Belt,Central Asia

Tectonic implications of Re-Os dating of molybdenum deposits...

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中国科学院地质与地球物理研究所2014年度（第14届）学术年会

作者： Chunming Han Wenjiao Xiao Guochun Zhao Benxun Su Songjian Ao Jien Zhang Zhiyong Zhang Bo Wan Zhongmei wang Key laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of Sciences Department of Earth Sciences The University of Hong Kong

The Tianshan–Xingmeng molybdenum belt is part of a larger E–W-trending metallogenic belt in northern *** of these molybdenum deposits occur as porphyry or porphyry-skarn type,but there are also some vein-type *** systematic Re-Os dating of molybdenite from four deposits and comparisons with two previously dated deposits,we conclude that molybdenum mineralization in the Tianshan–Xingmeng Orogenic Belt resulted from hydrothermal activity linked to the emplacement of granitoid *** pulses of granitoid magmatism and Mo mineralization have been recognized in this study,corresponding to tectonic events in the Tianshan–Xingmeng Orogenic *** identify five distinct stages of Mo mineralization events in the Tianshan–Xingmeng Orogenic Belt:320–250 Ma,250–200 Ma,190–155Ma,155–140 Ma,and 140–120 *** Palaeozoic(320–250 Ma)Mo mineralization was closely related to closure of the Palaeo-Asian Ocean and collision between the Siberia and Tarim ***(250–200 Ma)Mo mineralization occurred in a post-collisional tectonic *** Early–Middle Jurassic(190–155 Ma)Mo mineralization was related to subduction of the Palaeo-Pacific Ocean on the eastern Asian continental margin,whereas in the Erguna block,the Mo mineralization events were associated with the subduction of the Mongol–Okhotsk *** 155 to 120 Ma,large-scale continental extension occurred in the Tianshan–Xingmeng Orogenic Belt and surrounding ***,the Late Jurassic(150–140 Ma)Mo mineralization events in these areas evolved in a post-orogenic extensional environment of the Mongol–Okhotsk Ocean subduction *** Early Cretaceous(140–120 Ma)Mo mineralization occurred under the combined effects of the closure of the Mongol–Okhotsk Ocean and subduction of the Palaeo-Pacific Ocean.

关键词： Re-Os dating molybdenum deposits tectonic setting Tianshan–Xingmeng Orogenic Belt Central Asia

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TeV噪BlazarPKS2155-304中心双黑洞系统(英文)

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广州大学学报（自然科学版） 2012年第2期11卷 18-22页

作者：樊军辉广州大学天体物理中心广东广州510006

PKS2155-304是一个典型的TeV源,在全波段都观测到光变.文章利用GeVγ辐射和X辐射观测资料确定GeVγ辐射的基本参量以及相关黑洞质量,利用光学光变周期分析中心双黑洞系统的结构参量,并利用TeV的光变时标确定TeV辐射的区域大小以及离中... 详细信息

PKS2155-304是一个典型的TeV源,在全波段都观测到光变.文章利用GeVγ辐射和X辐射观测资料确定GeVγ辐射的基本参量以及相关黑洞质量,利用光学光变周期分析中心双黑洞系统的结构参量,并利用TeV的光变时标确定TeV辐射的区域大小以及离中心的距离.从分析得到如下结论:①在中心有一个双黑洞系统,大黑洞的质量是80.8×107太阳质量,而次黑洞的质量为(3.35-5.20)×107太阳质量.该双黑洞系统的半轴和为(3.67-5.15)×1016cm.②GeVγ辐射的参量与因子来自于离中心黑洞(次黑洞)18～20斯瓦西半径处.GeVγ辐射的Doppler因子为0.31～0.45,视角为8.5°～9.4°.这里的两个值分别对应于不同的系数λ.③TeVγ辐射来自于距中心2.5～2.8斯瓦西半径处.

关键词：星系-BL Lac天体-γ 辐射-喷流-黑洞-PKS2155-304

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