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A comprehensive review of phytochemical approaches in treatment of acute myeloid leukemia:Associated pathways and molecular mechanisms

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Chinese Herbal Medicines 2025年第1期17卷 41-55页

作者： Mouvanal Sajana T.S.Gopenath Basalingappa M.Kanthesh Division of Molecular Biology School of Life SciencesJSS AHER Department of Biotechnology and Bioinformatics School of Life SciencesJSS AHER

Acute myeloid leukemia(AML) is a type of cancer that affects the blood and bone *** review conducts a thorough analysis of AML, addressing its genetic *** examination extends to the current therapeutic approaches employed for AML,shedding light on their efficacy and the notable side effects experienced by patients undergoing these treatments,leading to a low overall survival ***,exploring alternative treatments,such as phytochemicals,is ***,the review explores the complex landscape of phytochemicals,categorizing them based on their diverse properties,which include alkaloids,phenols,terpenoids,organo-sulfur compounds,and other compounds,including quinones,and elucidating their mechanisms of *** emphasis is placed on their involvement in critical signaling pathways,with a particular focus on how these phytochemicals impact AML when evaluated across a spectrum of cell *** in-depth exploration aims to uncover potential targets within the molecular landscape of AML where phytochemicals can exert their therapeutic *** review investigates the potential role of plant-derived phytochemicals as adjunctive therapies for *** exploration encompasses the identification of specific phytochemicals that exhibit promising anti-leukemic properties and evaluates their potential in clinical *** conventional treatments,the review explores the integration of complementary and alternative medicine as a holistic approach to managing *** examination encompasses the synergy between conventional therapies and alternative interventions,exploring how these combined strategies may enhance overall therapeutic outcomes and mitigate side *** a forward-looking perspective,the overarching goal is to contribute to the evolving landscape of AML treatment by considering innovative approaches that harness the therapeutic potential of phytochemicals,both independently and in conjunction with establishe

关键词： cell death complementary and alternative medicine leukemia phytochemicals signaling pathways therapeutic targets

Synergistic effects of constituents in rare earth-based composites:Enhanced structural,electrical and magnetic properties for water splitting applications

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Journal of Rare Earths 2025年第1期43卷 105-114,I0005页

作者： Chitralekha S.Shankar A.P.Singh Functional Materials Research Laboratory Department of PhysicsARSD CollegeUniversity of Delhi1021India Department of Physics Multanimal Modi CollegeCh.Charan Singh UniversityMeerutU.PIndia

Rare earth-based Bi_(0.85)La_(0.15)FeO_(3)(BLFO)and NdMnO_(3)(NMO)particles were synthesised using the solidstate route,and their roles affecting structural,electrical,magnetic properties along with hydroelectric application in different concentrations i.e.,(1-x)BLFO:xNMO(where x=0,0.10,0.20,0.30 and 1.0)ceramics composites were investigated.X-ray diffraction analyses confirm the pure-phase formation of BLFO:NMO composites,featuring micrometer-scale crystallite *** transform infrared(FT-IR)spectra of BLFO:NMO composites reveal peak shifts with rising NMO content,indicating composite *** composites exhibit robust Maxwell-Wagner polarization and a pronounced composition-dependent *** addition of NMO to BLFO results in a rise in dielectric permittivity at lower frequencies,confirming relaxor behavior and indicating success in achieving the transition *** spectroscopy facilitates a clearer understanding of how charge carriers contribute to these composites and the impact of grain/grain *** saturation magnetization maximum value(i.e.,0.807 emu/g)was attained in *** coercivity decreases with the addition of NMO in *** results suggest the composite's enhanced suitability for microelectronics and hydropower cells,showing improved hydroelectric cell performance with increased NMO in BLFO,highlighting a notable ion diffusion mechanism.

关键词： Composites X-ray diffraction Relative permittivity Hydroelectric cell Rare earths

CHEMICAL SYNTHESIS,SPECTRAL CHARACTERIZATION AND STABILITY OF SOME ELECTRICALLY CONDUCTING POLYMERS

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Chinese Journal of Polymer Science 2010年第2期28卷 191-197页

作者： Pradeep Kumar Upadhyay Afaq Ahmad Department of Chemistry Aligarh Muslim University

The synthesis, characterization, thermal degradation and stability of polyaniline （PANI）, poly（m-nitroaniline）, poly（m-chloroaniline） and poly（o-methylaniline） were reported. Different properties were measured and compared with PANI to find out the effect of electron donating groups （-CH3） and electron withdrawing groups （-Cl, -NO2）. It was found that the presence of any type of substitution in the benzene ring of aniline increased the solubility but reduced the yield, thermal stability and electrical conductivity. Two probe methods were used to measure the electrical conductivity of these polymers. The structural properties of these polymers were characterized by using FTIR and UV-Vis spectroscopic methods. Thermal degradation and stability of these polymers were explained by using thermogravimetric analysis （TGA） and conductivity measurements.

关键词： Polyaniline Electrical conductivity Yield Thermal degradation Stability.

Electrical,Magnetic and Catalytic Investigations on Some Manganite Perovskites Prepared by Combustion Method

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Journal of Materials Science & Technology 2010年第12期26卷 1098-1102页

作者： R.G.Shetkar A.V.Salker Department of Chemistry Goa UniversityGoa 403206India

AMnO3 （A=Sr, Sm and Nd） manganites with perovskite structure, prepared by combustion method were characterized by X-ray diffraction （XRD）, infra-red spectroscopy, Brunauer-Emmett-Teller （BET） surface area analyzer and scanning electron microscopy （SEM）. The solid state and spectroscopic studies such as electrical resistivity, magnetic susceptibility, electron spin resonance （ESR） and diffuse reflectance spectroscopy were carried out and attempted to correlate with the catalytic activities of the compounds. To evaluate the catalytic activity, a model reaction of CO oxidation over these compounds was undertaken. An attempt was made to understand the effect of A-site change by different metal cations in the manganite perovskites on solid state and catalytic properties.

关键词： Perovskites Combustion method Solid state studies Carbon monoxide oxidation

Elastic and Optoelectronic Properties of KCdF3:ab initio Calculations through LDA/GGA/TB-mBJ within FP-LAPW Method

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Chinese Physics Letters 2015年第1期32卷 108-112页

作者： K. Ephraim Babu N. Murali K. Vijaya Babu B. Kishore Babu V. Veeraiah Modelling and Simulation in Materials Science Laboratory Department of Physics Andhra University Visakhapatnam 530003 Andhra Pradesh India Department of Engineering Chemistry A UCE(A) Andhra University Visakhapatnam 530003 Andhra Pradesh India

Ab initio calculations are performed on the electronic, structural, elastic and optical properties of the cubic per- ovskite KCdF3. Tile Kohn Sham equations are solved by applying the full potential linearized augmented plane wave （FP-LAPW） method. The exchange correlation effects are included through the local density approximation （LDA ）, generalized gradient approximation （GGA） and modified Becke-Johnson （mBJ） exchange potential The calculated lattice constant is in good agreement with the experimental result. The elastic properties such as elastic constants, anisotropy factor, shear modulus, Young＇s modulus and Poisson＇s ratio are calculated. KCdF3 is ductile and elastically anisotropic. The calculations of the electronic band structure, density of states （DOS） and charge density show that this compound has an indirect energy band gap （M-F） with a mixed ionic and covalent bonding. The contribution of the different bands is analyzed from the total and partial density of states curves. Optical response of the dielectric functions, optical reflectivity, absorption coefficient, real part of optical conductivity, refractive index, extinction coefficient and electron energy loss, are presented for the energy range of O-40eV. The compound KCdF3 can be used for high-frequency optical and optoelectronic devices.

关键词： GGA Cd Elastic and Optoelectronic Properties of KCdF3:ab initio Calculations through LDA/GGA/TB-mBJ within FP-LAPW Method LDA FP

A model for virtual network embedding across multiple infrastructure providers using genetic algorithm

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Science China(Information Sciences) 2017年第4期60卷 101-112页

作者： Isha PATHAK Deo Prakash VIDYARTHI School of Computer and Systems Sciences Jawaharlal Nehru University

Network virtualization is an important aspect in cloud computing, where network is assumed to be consisting of infinite amount of nodes and links. The substrate network(physical network), has limited capacity and so virtual network embedding on the substrate network becomes a problem. Virtual network embedding is a computationally hard problem, considering various constraints on nodes and links. The proposed work applies Genetic Algorithm for the virtual network embedding problem for mapping multiple virtual network requests on infrastructure providers managing multiple substrate networks. Performance evaluation, through simulations,indicates that the proposed model preforms better for the performance metrics such as infrastructure provider revenue, acceptance ratio and node and link utilization in comparison to few other contemporary mapping models.

关键词： network virtualization virtual network embedding substrate network NP-hard genetic algorithm

Energy Spectra of the Coulomb Perturbed Potential in N-Dimensional Hilbert Space

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Chinese Physics Letters 2012年第6期29卷 35-38页

作者： Ramesh Kumar Fakir Chand Department of Physics Kurukshetra UniversityKurukshetra-136119India

We deal with the solutions to the radial Schr(o)dinger equation for the Coulomb perturbed potential in Ndimensional Hilbert space by using two methods,*** power series technique via a suitable ansatz to the wavefunction and the Virial *** expressions for eigenvalues and normalized eigenfunctions are derived.A recursion relation among series expansion coefficients,a condition for convergence of series and interdimensional degeneracies are also *** special cases,the problem is solved in 3 and 4 dimensions with some specific parameter *** obtained analytical and numerical results are in good agreement with the results of other studies.

关键词： dimensions normalized perturbed

Formation of E-cyanomethamine in a nitrile rich environment

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Research in Astronomy and Astrophysics 2017年第1期17卷 1-10页

作者： Shivani Alka Misra Poonam Tandon Department of Mathematics & Astronomy University of Lucknow Lucknow India Department of Physics University of Lucknow Lucknow 226007 India

Recently a new molecule, cyanomethamine, has been detected towards Sagittarius B2（N）（Sgr B2（N））. Studying the formation mechanisms of complex interstellar molecules is difficult. Hence, a theoretical quantum chemical approach for analyzing the reaction mechanism describing the forma- tion of interstellar cyanomethamine through detected interstellar molecules and radicals （NCCN＋H） is discussed in the present work. Calculations are performed by using quantum chemical techniques, such as Density Functional Theory （DFT） and Mφ11er-Plesset perturbation （MP2） theory with a 6-311G（d,p） basis set, both in the gas phase and in icy grains. The proposed reaction path （NCCN＋H＋H） has exother- micity with no barrier which indicates the possibility of cyanomethamine formation in the interstellar medium.

关键词： interstellar medium: abundances general - general: extraterrestrial intelligence - mete-orites - individual: Sgr B2(N) region

Lattice thermal conduction in cadmium arsenide

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Chinese Physics B 2022年第11期31卷 424-430页

作者： R F Chinnappagoudra M D Kamatagi N R Patil N S Sankeshwar Department of Physics S.S.Government First Grade CollegeNargund-582207KarnatakaIndia Research Resource Centre Visvesvaraya Technological UniversityBelagavi-590018KarnatakIndia Department of Physics B V B College of Engineering and TechnologyHubliKarnataka 80031India Department of Physics&Electronics CHRIST(Deemed to be University)Bangalore-560029KarnatakaIndia

Lattice thermal conductivity(LTC)of cadmium arsenide(Cd_(3)As_(2))is studied over a wide temperature range(1–400 K)by employing the Callaway *** acoustic phonons are considered to be the major carriers of heat and to be scattered by the sample boundaries,disorder,impurities,and other phonons via both Umklapp and normal phonon *** calculations of LTC of Cd_(3)As_(2)bring out the relative importance of the scattering *** systematic analysis of recent experimental data on thermal conductivity(TC)of Cd_(3)As_(2)samples of different groups,presented in terms of LTC,κL,using a nonlinear regression method,reveals good fits to the TC data of the samples considered for T100 K the inclusion of the electronic component of TC,κe,incorporating contributions from relevant electron scattering mechanisms,is needed to obtain good agreement with the TC data over the wide temperature *** detailed investigations of TC of Cd_(3)As_(2)are required to better understand its suitability in thermoelectric and thermal management devices.

关键词： dirac semimetals Cd_(3)As_(2) thermal conductivity phonon scattering