检索结果-南通市图书馆

Immunological Exploration of Helicobacter pylori Serotype O_(2) O-Antigen by Using a Synthetic Glycan Library

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第3期42卷 243-251页

作者： Ming Zhao Guangzong Tian Chunjun Qin Xiaopeng Zou Peter H. Seeberger Jing Hu Jian Yin Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of Biotechnology & School of Life Sciences and Health EngineeringJiangnan UniversityLihu Avenue 1800WuxiJiangsu214122 China Biomolecular Systems Department Max Planck Institute of Colloids and InterfacesAm Mühlenberg 1Potsdam14476 Germany Wuxi School of Medicine Jiangnan UniversityLihu Avenue 1800WuxiJiangsu214122 China

Helicobacter pylori(***)infection is a threat to human *** lipopolysaccharide(LPS)O-antigen holds promise for developing *** is meaningful to explore the immunological activity of oligosaccharides with different lengths and frameshifts for antigen ***,a glycan library of *** O2 O-antigen containing eight fragments is *** screening with *** O2 LPS sera and patients’sera by glycan microarray,the disaccharide HPO2G-2b and trisaccharide HPO2G-3a show strong antigenicity and then are separately conjugated with carrier protein *** glycoconjugates elicit a robust immunoglobulin G(IgG)immune response in *** anti-HPO2G-3a IgG antibodies possess a much stronger binding affinity with the LPS and bacteria of *** O2 than the anti-HPO2G-2b IgG *** is no cross-reaction between both sera IgG antibodies with LPS and bacteria of *** O1,O6,and *** results demonstrate the trisaccharide HPO2G-3a is a promising candidate for *** vaccine development.

关键词： Glycoconjugates Helicobacter pylori Immunology Microarrays O-antigen Oligosaccharides

The Precursor of GRB211211A:A Tide-induced Giant Quake?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第2期24卷 206-215页

作者： Enping Zhou Yong Gao Yurui Zhou Xiaoyu Lai Lijing Shao Weiyang Wang Shaolin Xiong Renxin Xu Shuxu Yi Garvin Yim Han Yue Zhen Zhang School of Physics Huazhong University of Science and TechnologyWuhan 430074China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China School of Physics Peking UniversityBeijing 100871China Research Center for Astronomy Hubei University of EducationWuhan 430205China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Earth and Space Sciences Peking UniversityBeijing 100871China

The equilibrium configuration of a solid strange star in the final inspiral phase with another compact object is generally discussed,and the starquake-related issue is revisited,for a special purpose to understand the precursor emission of binary compact star merger events(e.g.,that of GRB211211A).As the binary system inspirals inward due to gravitational wave radiation,the ellipticity of the solid strangeon star increases due to the growing tidal field of its compact *** energy is hence accumulated during the inspiral stage which might trigger a starquake before the merger when the energy exceeds a critical *** energy released during such starquakes is calculated and compared to the precursor observation of GRB211211 *** result shows that the energy might be insufficient for binary strangeon-star case unless the entire solid strangeon star shatters,and hence favors a black hole-strangeon star scenario for *** timescale of the precursor as well as the frequency of the observed quasi-periodic-oscillation have also been discussed in the starquake model.

关键词： stars neutron-(stars:)gamma-ray burst general-black hole physics

On-Surface Synthesis of Anthracene-Fused Zigzag Graphene Nanoribbons from 2,7-Dibromo-9,9′-bianthryl Reveals Unexpected Ring Rearrangements

在线全文

学校读者我要写书评

暂无评论

Precision Chemistry 2024年第2期2卷 81-87页

作者： Xiushang Xu Amogh Kinikar Marco Di Giovannantonio Carlo A.Pignedoli Pascal Ruffieux Klaus Müllen Roman Fasel Akimitsu Narita max planck Institute for Polymer Research 55128 MainzGermany Organic and Carbon Nanomaterials Unit Okinawa Institute of Science and Technology Graduate UniversityKunigami-gunOkinawa 904-0495Japan Empa Swiss Federal Laboratories for Materials Science and Technologynanotech@surfaces Laboratory8600 DübendorfSwitzerland Institute of Structure of Matter-CNR(ISM-CNR) 00133 RomaItaly Institute of Physical Chemistry Johannes Gutenberg University Mainz55128 MainzGermany Department of Chemistry Biochemistry and Pharmaceutical SciencesUniversity of Bern3012 BernSwitzerland

On-surface synthesis has emerged as a powerful strategy to fabricate unprecedented forms of atomically precise graphene nanoribbons(GNRs).However,the on-surface synthesis of zigzag GNRs(ZGNR)has met with only limited ***,we report the synthesis and on-surface reactions of 2,7-dibromo-9,9′-bianthryl as the precursor towardπ-extended *** by scanning tunneling microscopy and high-resolution noncontact atomic force microscopy clearly demonstrated the formation of anthracene-fused *** skeletal rearrangements were also observed,which could be explained by intramolecular Diels-Alder *** calculations of the electronic properties of the anthracene-fused ZGNRs revealed spin-polarized edge-states and a narrow bandgap of 0.20 eV.

关键词： On-surface synthesis Graphene nanoribbon On-surface reaction Rearrangement Edge state

Dynamic carbon surface chemistry: Revealing the role of carbon in electrolytic water oxidation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2020年第8期29卷 155-159,I0006页

作者： Yuxiao Ding Qingqing Gu Alexander Klyushin Xing Huang Sakeb H.Choudhury Ioannis Spanos Feihong Song Rik Mom Pascal Dungen Anna K.Mechler Robert Schlogl Saskia Heumann max planck Institute for Chemical Energy Conversion Stiftstrasse 34-36Mtilheim an der Ruhr 45470Germany Fritz-Haber-Institut der max-planck Gesellschaft Faradayweg 4-6Berlin 14195Germany Research Group Catalysis for Energy Helmholtz-Zentrum Berlin fur Materialien und Energie GmbHAlbert-Einstein-Strasse 1512489 BerlinGermany

Carbon materials have been widely used as electrodes, but the mechanistic roles are still not clear due to the complexity of the carbon surface chemistry. Herein we clarify that intrinsic material properties of carbon have to be activated by extrinsic factors. Pure carbon has no catalytic activity when used as electrode for electrocatalytic water oxidation. The evolution of oxygen functional groups on the carbon surface with increasing potential and the subsequent formation of real active sites with iron impurities from the electrolyte have been confirmed. These in-situ formed active sites protect the carbon from deep oxidation. This unprecedented finding not only provides insight into the dynamic evolution of carbon electrode surface chemistry and raises awareness of the need for detailed surface analysis under operando conditions, but also suggests a direction for the development of scalable and high-performance carbonbased electrode systems for various electrochemical applications.

关键词： Carbon chemistry Carbon catalysis Carbon electrode Water splitting Iron impurity

Pectin May Hinder the Unfolding of Xyloglucan Chains during Cell Deformation： Implications of the Mechanical Performance of Arabidopsis Hypocotyls with Pectin Alterations

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2009年第5期2卷 990-999页

作者： Willie Abasolo Michaela Eder Kazuchika Yamauchi Nicolai Obel Antje Reinecke Lutz Neumetzler John W.C. Dunlop Gregory Mouille Markus Pauly Herman Hofte Ingo Burgert max-planck-lnstitute of Colloids and Interfaces Department of Biomaterials Potsdam Germany College of Forestry and Natural Resources University of the Philippines Los Banos Philippines Department of Socio-Environmental Energy Science Kyoto University Japan max-planck-lnstitute for Molecular Plant Physiology Potsdam Germany Laboratoire de Biologie Cellulaire UR501 Institute Jean-Pierre Bourgin INRA Versailles France Michigan State University Plant Research Laboratory East Lansing Michigan USA

Plant cell walls, like a multitude of other biological materials, are natural fiber-reinforced composite materials. Their mechanical properties are highly dependent on the interplay of the stiff fibrous phase and the soft matrix phase and on the matrix deformation itself. Using specific Arabidopsis thaliana mutants, we studied the mechanical role of the matrix assembly in primary cell walls of hypocotyls with altered xyloglucan and pectin composition. Standard microtensile tests and cyclic loading protocols were performed on tour1 hypocotyls with affected RGII borate diester cross-links and a hindered xyloglucan fucosylation as well as qua2 exhibiting 50% less homogalacturonan in comparison to wild-type. As a control, wild-type plants （Col-0） and mur2 exhibiting a specific xyloglucan fucosylation and no differences in the pectin network were utilized. In the standard tensile tests, the ultimate stress levels （-tensile strength） of the hypocotyls of the mutants with pectin alterations （mur1, qua2） were rather unaffected, whereas their tensile stiffness was noticeably reduced in comparison to Col-0. The cyclic loading tests indicated a stiffening of all hypocotyls after the first cycle and a plastic deformation during the first straining, the degree of which, however, was much higher for tour1 and qua2 hypocotyls. Based on the mechanical data and current cell wall models, it is assumed that folded xyloglucan chains between cellulose fibrils may tend to unfold during straining of the hypocotyls. This response is probably hindered by geometrical constraints due to pectin rigidity.

关键词： Arabidopsis thaliana mutants cellulose xyloglucan pectin cyclic loading tests.

Model-based optimal design of phase change ionic liquids for efficient thermal energy storage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green Energy & Environment 2021年第3期6卷 392-404页

作者： Huaiwei Shi Xiang Zhang Kai Sundmacher Teng Zhou Process Systems Engineering Otto-von-Guericke University MagdeburgUniversitätsplatz 2MagdeburgD-39106Germany Process Systems Engineering Max Planck Institute for Dynamics of Complex Technical SystemsSandtorstr.1MagdeburgD-39106Germany

The selection of phase change material(PCM)plays an important role in developing high-efficient thermal energy storage(TES)*** liquids(ILs)or organic salts are thermally stable,non-volatile,and ***,researchers have proved that some ILs possess higher latent heat of fusion than conventional *** these attractive characteristics,yet surprisingly,little research has been performed to the systematic selection or structural design of ILs for ***,most of the existing work is only focused on the latent heat when selecting ***,one should note that other properties such as heat capacity and thermal conductivity could affect the TES performance as *** this work,we propose a computer-aided molecular design(CAMD)based method to systematically design IL PCMs for a practical TES *** effects of different IL properties are simultaneously captured in the IL property models and TES process *** ILs holding a best compromise of all the properties are identified through the solution of a formulated CAMD problem where the TES performance of the process is maximized.[MPyEtOH][TfO]is found to be the best material and excitingly,the identified top nine ILs all show a higher TES performance than the traditional PCM paraffin wax at 10 h thermal charging time.

关键词： Ionic liquid Phase change material Thermal energy storage Computer-aided molecular design Process modelling and evaluation

Atomic structures of twin boundaries in hexagonal closepacked metallic crystals with particular focus on Mg

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2017年第1期3卷 435-441页

作者： Zongrui Pei Xie Zhang Tilmann Hickel Martin Friak Stefanie Sandlobes Biswanath Dutta Jorg Neugebauer max-planck-Institut fur Eisenforschung Dusseldorf D-40237Germany Institute of Physics of Materials Academy of Sciences of the Czech Republicv.v.i.Zizkova 22Brno CZ-61662Czech Republic Institut fur Metallkunde und Metallphysik RWTH Aachen UniversityAachen D-52074Germany Oak Ridge National Laboratory Oak RidgeTN 37831USA

We have investigated twin boundaries in double-lattice hexagonal close-packed metallic materials,focusing on their atomic *** accurate ab-initio methods and large-scale atomistic simulations we address the following two fundamental questions:(i)What are the possible intrinsic twin boundary structures in hcp crystals?(ii)Are these structures stable against small distortions?In order to help end a decade-long controversy over the experimental observations of the atomic structures of twin boundaries,we have determined the energetics,spectra,and transition mechanisms of the twin *** results confirm that the mechanical stability controls structures which are observed.

关键词： twin hexagonal metallic

Hybrid Data-Driven and Mechanistic Modeling Approaches for Multiscale Material and Process Design

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2021年第9期7卷 1231-1238页

作者： Teng Zhou Rafiqul Gani Kai Sundmacher Process Systems Engineering Max Planck Institute for Dynamics of Complex Technical SystemsMagdeburg D-39106Germany Process Systems Engineering Otto-von-Guericke University MagdeburgMagdeburg D-39106Germany PSE for SPEED Co. Ltd.Allerod DK 3450Denmark Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea

The world’s increasing population requires the process industry to produce food,fuels,chemicals,and consumer products in a more efficient and sustainable *** process materials lie at the heart of this ***,new advanced materials are found empirically or through trial-and-error *** theoretical methods and associated tools are being continuously improved and computer power has reached a high level,it is now efficient and popular to use computational methods to guide material selection and *** to the strong interaction between material selection and the operation of the process in which the material is used,it is essential to perform material and process design *** this significant connection,the solution of the integrated material and process design problem is not easy because multiple models at different scales are usually *** modeling provides a promising option to tackle such complex design *** hybrid modeling,the material properties,which are computationally expensive to obtain,are described by data-driven models,while the well-known process-related principles are represented by mechanistic *** article highlights the significance of hybrid modeling in multiscale material and process *** generic design methodology is first *** important application areas are then selected:four from the chemical engineering field and two from the energy systems engineering *** each selected area,state-ofthe-art work using hybrid modeling for multiscale material and process design is *** remarks are provided at the end,and current limitations and future opportunities are pointed out.

关键词： Data-driven Surrogate model Machine learning Hybrid modeling Material design Process optimization

DICER-like Proteins and Their Role in Plant-herbivore Interactions in Nicotiana attenuata

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2012年第3期54卷 189-206页

作者： Tohir Ahmadovich Bozorov Shree Prakash Pandey Son Truong Dinh Sang-Gyu Kim Maria Heinrich Klaus Gase Ian T. Baldwin Department of Molecular Ecology Max Planck Institute for Chemical Ecology 07745 Jena Germany Department of Biological Sciences Indian Institute of Science Education and Research Kolkata Mohanpur CampusPO: BCKV Campus Main Office Mohanpur Nadia West Bengal 741252 India.

DICER-like （DCL） proteins produce small RNAs that silence genes involved in development and defenses against viruses and pathogens. Which DCLs participate in plant-herbivore interactions remains unstudied. We identified and stably silenced four distinct DCL genes by RNAi in Nicotiana attenuata （Torrey ex. Watson）, a model for the study of plant-herbivore interactions. Silencing DCL1 expression was lethal. Manduca sexta larvae performed significantly better on ir-dcl3 and ir-dcl4 plants, but not on ir-dcl2 plants compared to wild type plants. Phytohormones, defense metabolites and microarray analyses revealed that when DCL3 and DCL4 were silenced separately, herbivore resistance traits were regulated in distinctly different ways. Crossing of the lines revealed complex interactions in the patterns of regulation. Single ir-dcl4 and double ir-dcl2 ir-dcl3 plants were impaired in JA accumulation, while JA- Ile was increased in ir-dcl3 plants. Ir-dcl3 and ir-dcl4 plants were impaired in nicotine accumulation; silencing DCL2 in combination with either DCL3 or DCL4 restored nicotine levels to those of WT. Trypsin proteinase inhibitor activity and transcripts were only silenced in ir-dcl3 plants. We conclude that DCL2/3/4 interact in a complex manner to regulate anti-herbivore defenses and that these interactions significantly complicate the already challenging task of understanding smRNA function in the regulation of biotic interactions.

关键词： DICER-like proteins anti-herbivore defense phytohormone signaling Manduca sexta Nicotiana attenuata.