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Using Susceptible-Exposed-Infectious-Recovered Model to Forecast Coronavirus Outbreak

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Computers, Materials & Continua 2021年第5期67卷 1595-1612页

作者： Debabrata Dansana Raghvendra Kumar Arupa Parida Rohit Sharma Janmejoy Das Adhikari Hiep Van Le Binh Thai Pham Krishna Kant Singh Biswajeet Pradhan Department of Computer Science and Engineering GIET UniversityGunupurOdishaIndia Department of Electronics&Communication Engineering Faculty of Engineering and TechnologySRM Institute of Science and TechnologyNCR CampusDelhi-NCR CampusModinagarGhaziabadIndia Institute of Research and Development Duy Tan UniversityDa Nang550000Viet Nam University of Transport Technology Hanoi100000Viet Nam Department of ECE KIET Group of InstitutionsGhaziabadIndia Centre for Advanced Modelling and Geospatial Information Systems(CAMGIS) University of Technology SydneySydneyNSW2007Australia Department of Energy and Mineral Resources Engineering Sejong UniversitySeoul05006Korea Center of Excellence for Climate Change Research King Abdulaziz UniversityJeddah21589Saudi Arabia Earth Observation Center Institute of Climate ChangeUniversiti Kebangsaan Malaysia43600SelangorMalaysia

The Coronavirus disease 2019(COVID-19)outbreak was rst discovered in Wuhan,China,and it has since spread to more than 200 *** World Health Organization proclaimed COVID-19 a public health emergency of international concern on January 30,***,a quickly spreading infection that could jeopardize the well-being of countless individuals requires prompt action to forestall the malady in a timely ***19 is a major threat worldwide due to its ability to rapidly *** vaccines are yet available for *** objective of this paper is to examine the worldwide COVID-19 pandemic,specically studying Hubei Province,China;Taiwan;South Korea;Japan;and Italy,in terms of exposed,infected,recovered/deceased,original conrmed cases,and predict conrmed cases in specic countries by using the susceptible-exposed-infectious-recovered model to predict the future outbreak of *** applied four differential equations to calculate the number of conrmed cases in each country,plotted them on a graph,and then applied polynomial regression with the logic of multiple linear regression to predict the further spread of the *** also compared the calculated and predicted cases of conrmed population and plotted them in the graph,where we could see that the lines of calculated and predicted cases do intersect with each other to give the perfect true results for the future spread of the *** study considered the cases from 22 January 2020 to 25 April 2020.

关键词： COVID-19 SEIR forecasting global pandemic predict conrmed case

Dopamine: an immune transmitter

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Neural Regeneration Research 2020年第12期15卷 2173-2185页

作者： Sarah Thomas Broome Krystal Louangaphay Kevin AKeay Gian Marco Leggio Giuseppe Musumeci Alessandro Castorina Laboratory of Cellular and Molecular Neuroscience(LCMN) School of Life ScienceFaculty of ScienceUniversity of Technology SydneySydneyAustralia Laboratory of Neural Structure and Function(LNSF) School of Medical Sciences(Anatomy and Histology)Faculty of Medicine and HealthUniversity of SydneySydneyAustralia Section of Pharmacology Department of Biomedical and Biotechnological SciencesUniversity of CataniaCataniaItaly Section of Human Anatomy and Histology Department of Biomedical and Biotechnological SciencesUniversity of CataniaCataniaItaly

The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesis of neurodegenerative and psychiatric disorders, in particular Parkinson’s disease, which are associated with a subtle and chronic inflammatory response. A substantial body of evidence has demonstrated the non-neuronal expression of dopamine, its receptors and of the machinery that governs synthesis, secretion and storage of dopamine across several immune cell types. This review aims to summarize current knowledge on the role and expression of dopamine in immune cells. One of the goals is to decipher the complex mechanisms through which these cell types respond to dopamine, in order to address the impact this has on neurodegenerative and psychiatric pathologies such as Parkinson’s disease. A further aim is to illustrate the gaps in our understanding of the physiological roles of dopamine to encourage more targeted research focused on understanding the consequences of aberrant dopamine production on immune regulation. These highlights may prompt scientists in the field to consider alternative functions of this important neurotransmitter when targeting neuroinflammatory/neurodegenerative pathologies.

关键词： astrocyte autoimmune disease dopamine dopamine receptors D3R immune transmitter microglia multiple sclerosis neuroinflammation Parkinson’s disease

Integrated model for earthquake risk assessment using neural network and analytic hierarchy process:Aceh province,Indonesia

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Geoscience Frontiers 2020年第2期11卷 613-634页

作者： Ratiranjan Jena Biswajeet Pradhan Ghassan Beydoun Nizamuddin Ardiansyah Hizir Sofyan Muzailin Affan Centre for Advanced Modelling and Geospatial Information Systems(CAMGIS) School of InformationSystems and ModellingUniversity of Technology SydneyNSW2007Australia Department of Energy and Mineral Resources Engineering Choongmu-gwanSejong University209 Neungdong-roGwangjin-guSeoul05006South Korea Department of Informatics Syiah Kuala UniversityBanda AcehIndonesia Department of Statistics Syiah Kuala UniversityBanda AcehIndonesia

Catastrophic natural hazards,such as earthquake,pose serious threats to properties and human lives in urban ***,earthquake risk assessment(ERA)is indispensable in disaster *** is an integration of the extent of probability and vulnerability of *** study develops an integrated model by using the artificial neural network–analytic hierarchy process(ANN–AHP)model for constructing the ERA *** aim of the study is to quantify urban population risk that may be caused by impending *** model is applied to the city of Banda Aceh in Indonesia,a seismically active zone of Aceh province frequently affected by devastating *** is used for probability mapping,whereas AHP is used to assess urban vulnerability after the hazard map is created with the aid of earthquake intensity variation thematic *** risk map is subsequently created by combining the probability,hazard,and vulnerability ***,the risk levels of various zones are *** validation process reveals that the proposed model can map the earthquake probability based on historical events with an accuracy of 84%.Furthermore,results show that the central and southeastern regions of the city have moderate to very high risk classifications,whereas the other parts of the city fall under low to very low earthquake risk *** findings of this research are useful for government agencies and decision makers,particularly in estimating risk dimensions in urban areas and for the future studies to project the preparedness strategies for Banda Aceh.

关键词： Earthquake Hazard Vulnerability Risk GIS ANN–AHP

Precise Pentamers with Diverse Monomer Sequences and Their Thermal Properties

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Chinese Journal of Polymer Science 2022年第5期40卷 447-455页

作者： Rui-Zhe Liu Lei Zhang Kun-Kun Guo Jiang-Tao Xu School of Chemical Engineering UNSW SydneyNSW2052Australia College of Materials Science and Engineering Hunan UniversityChangsha 470082China

Sequenced-defined oligomer has been emerged as one of the hot topics in polymer chemistry due to its capability of precisely controlling both chain length and monomer *** efforts have focused on development of synthetic methodologies using state-ofthe-art chemistry ***,investigating the impact of minor changes in monomer sequence on physical properties of these materials is still ***,four sequenced pentamers are synthesized by a reversible addition-fragmentation chain transfer(RAFT)single unit monomer insertion technique,in which a base pentamer possesses a relatively rigid backbone comprising of five cyclic monomer *** of the cyclic units in this base pentamer is replaced by an acyclic monomer at different locations(the 1st,3rd and 5th unit)to produce three modified pentamers,which leads to a significant decrease of glass transition temperature(Tg)compared to the base ***,the modified pentamers with identical primary structures but distinct monomer sequences also present different Tg values depending on the position of the acyclic monomer *** middle(3rd)position of the acyclic unit causes profound decrease of Tg due to its increased molecular *** synthetic pentamers have been demonstrated to be excellent oligomeric plasticizers to modulate thermal transitions of bulk polymer materials.

关键词： Pentamer Sequence control Single unit monomer insertion Glass transition temperature Sequence-defined oligomer

Biomarkers of Metabolic(Dysfunction)-associated Fatty Liver Disease:An Update

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Journal of Clinical and Translational Hepatology 2022年第1期10卷 134-139页

作者： Jawaher Alharthi Mohammed Eslam Storr Liver Centre Westmead Institute for Medical ResearchWestmead Hospital and University of SydneySydneyNSWAustralia Department of Biotechnology Faculty of ScienceTaif UniversityTaifSaudi Arabi

The prevalence of metabolic(dysfunction)-associated fatty liver disease(MAFLD)is rapidly increasing and affects up to two billion individuals globally,and this has also resulted in increased risks for cirrhosis,hepatocellular carcinoma,and liver *** addition,it has also been linked to extrahepatic consequences,such as cardiovascular disease,diabetes,and various types of ***,only a small proportion of patients with MAFLD develop these ***,the identification of high-risk patients is *** fibrosis is the major determinant in developing these ***,liver biopsy is still considered the gold standard for the assessment of patients with *** of its invasive nature,among many other limitations,the search for noninvasive biomarkers for MAFLD remains an area of intensive *** this review,we provide an update on the current and future biomarkers of MAFLD,including a discussion of the associated genetics,epigenetics,microbiota,and *** also touch on the next wave of multiomic-based biomarkers.

关键词： Biomarkers Metabolic(dysfunction)-associated fatty liver disease Scores

Microbe-derived carbon materials for electrical energy storage and conversion

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Journal of Energy Chemistry 2016年第2期25卷 189-196页

作者： Li Wei H.Enis Karahan Shengli Zhai Yang Yuan Qihui Qian Kunli Goh Andrew Keong Ng Yuan Chen School of Chemical and Biomedical Engineering Nanyang Technological University 62 Nanyang Drive 637459 Singapore Singapore Institute of Technology 10 Dover Drive 138683 Singapore School of Chemical and Biomolecular Engineering The University of Sydney NSW 2006 Australia

Microbes are microscopic living organisms that surround us which include bacteria, archaea, most protozoa, and some fungi and algae. In recent years, microbes have been explored as novel precursors to synthesize carbon-based（nano）materials and as substrates or templates to produce carbon-containing（nano）composites. Being greener and more affordable, microbe-derived carbons（MDCs） offer good potential for energy applications. In this review, we describe the unique advantages of MDCs and outline the common procedures to prepare them. We also extensively discuss the energy applications of MDCs including their use as electrodes in supercapacitors and lithium-ion batteries, and as electrocatalysts for processes such as oxygen reduction, oxygen evolution, and hydrogen evolution reactions which are essential for fuel cell and water electrochemical splitting cells. Based on the literature trend and our group＇s expertise, we propose potential research directions for developing new types of MDCs. This review, therefore, provides the state-of-the-art of a new energy chemistry concept. We expect to stimulate future research on the applications of MDCs that may address energy and environmental challenges that our societies are facing.

关键词： Microbe Carbon materials Supercapacitor Lithium-ion battery Oxygen reduction reaction Hydrogen evolution reaction

A comparative study of Salvia miltiorrhiza Radix & Rhizoma raw material and granule products using chromatographic analysis and antioxidant activity

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Journal of Traditional Chinese Medical Sciences 2022年第3期9卷 311-320页

作者： Xian Zhou Valentina Razmovski-Naumovski Raynold Mendoza John Truong Kelvin Chan NICM Health Research Institute Western Sydney UniversityWestmead2145Australia South West sydney Clinical Campuses Faculty of Medicine&HealthUniversity of New South WalesSydneyNSW2170Australia School of Pharmacy and Biomolecular Sciences Liverpool John Moores UniversityLiverpoolL33AFUK

Objective: Granules of herbal extracts are a popular medicinal preparation consumed in traditional Chinese medicine clinical practice. However, their quality and efficacy evaluation are lacking. This study aimed to compare the quality and anti-oxidant activity of Dan Shen(Salvia miltiorrhiza Radix & Rhizoma)granule extracts with their herbal ***: Chromatographic method was used to determine the content of 7 marker compounds in the water extracts of the herb compared to that of 12 granule extracts. Agglomerative hierarchical clustering(AHC) and principal component analysis(PCA) distinguished the herbal and granule extracts based on the content of the marker compounds. The antioxidant activities of herbal and granule extracts were evaluated by 2, 2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid)(ABTS), organic chemical compound 2,2-diphenyl-1-picrylhydrazyl(DPPH) and ferric ion reducing antioxidant power(FRAP) ***: The herbal extracts group showed significantly higher contents of salvianolic acid B, sodium danshensu and cryptotanshinone compared with that of the granule group. This corresponded to significantly higher ABTS, DPPH and FRAP(P <.05) activities of the herbal extracts. The AHC and PCA analysis distinguished granule extracts from most herbal extracts predominantly by the content of salvianolic acid ***: The results confirm the need for the assessment of granule products so that healthcare practitioners and consumers are better informed of their quality and efficacy.

关键词： Dan Shen Granule Multivariate analysis Salvia miltiorrhiza Radix&rhizoma Ultra-performance liquid chromatography Antioxidant

Current management of gastro-oesophageal reflux disease—treatment costs,safety profile,and effectiveness:a narrative review

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Gastroenterology Report 2023年第1期11卷 95-113页

作者： Tahmina Lata Jodie Trautman Philip Townend Robert B.Wilson Faculty of Medicine and Health University of SydneyCamperdownNSWAustralia Upper Gastrointestinal Surgery Department University of New South WalesLiverpool HospitalLiverpoolNSWAustralia General Surgery Department Wollongong HospitalWollongongNSWAustralia General Surgery Department Gold Coast University HospitalSouthportQLDAustralia

Background The purpose of this study was to review the current management of gastro-oesophageal reflux disease(GORD),including treatment costs,safety profile and *** A literature review was performed of randomized-controlled trials,systematic reviews,Cochrane reports and National/Societal guidelines of themedical,endoscopic and surgicalmanagement of *** pump inhibitor(PPI)prescribing patterns and expenditure were reviewed in different countries,including Australia,Canada,New Zealand,UK and *** Proton pump inhibitors(PPIs)are primarily indicated for control of GORD,Helicobacter pylori eradication(combined with antibiotics),preventing NSAID-induced gastrointestinal bleeding and treating peptic ulcer *** is widespread overprescribing of PPIs in Western and Eastern nations in terms of indication and duration,with substantial expense for national health *** a favourable short-term safety profile,there are observational associations of adverse effects with long-term *** include nutrient malabsorption,enteric infections and cardiovascular *** prevalence of PPI use makes their long-termsafety profile clinically ***-benefit,symptom control and quality-oflife outcomes favour laparoscopic fundoplication rather than chronic PPI *** fundoplication in long-termmanagement of PPI-responsive GORD is supported by SAGES,NICE and ACG,and PPI-refractory GORD by AGA and SAGES *** importance of establishing a definitive diagnosis prior to invasive management is emphasized,especially in PPI-refractory *** We examined evidence-based guidelines for PPI prescribing and deprescribing in primary care and hospital settings and the need for PPI stewardship and education of health *** narrative review presents the advantages and disadvantages of surgical,endoscopic and medical management of GORD,which may assist in shared decision making and treatment cho

关键词： Canada treatment establishing

Millimetric devices for nerve stimulation:a promising path towards miniaturization

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Neural Regeneration Research 2024年第8期19卷 1702-1706页

作者： Ryan M.Dorrian Anna V.Leonard Antonio Lauto Spinal Cord Injury Research Group School of BiomedicineThe University of AdelaideAdelaideSAAustralia School of Science Western Sydney UniversityPenrithNSWAustralia

Nerve stimulation is a rapidly developing field,demonstrating positive outcomes across several *** potential benefits,current nerve stimulation devices are large,complicated,and are powered via implanted pulse *** facto rs necessitate invasive surgical implantation and limit potential *** nerve stimulation devices to millimetric sizes would make these interventions less invasive and facilitate broader therapeutic ***,device miniaturization presents a serious engineering *** review presents significant advancements from several groups that have overcome this challenge and developed millimetricsized nerve stimulation *** are based on antennas,mini-coils,magneto-electric and optoelectronic materials,or receive ultrasound *** highlight key design elements,findings from pilot studies,and present several considerations for future applications of these devices.

关键词： biomedical engineering deep brain stimulation electrical engineering electrical stimulation neuromodulation peripheral nerve stimulation