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Temporary self-expanding metallic stents for achalasia: A prospective study with a long-term follow-up

World Journal of Gastroenterology 2010年第40期16卷 5111-5117页

作者： Ying-Sheng Cheng Fang Ma Ying-Sheng Cheng Yong-Dong Li Jun-Gong Zhao Chun-Gen Wu Ni-Wei Chen Wei-Xiong Chen Department of Clinical Center of Imaging Medicine The Tenth Affiliated People’s Hospital Tongji University shanghai 200072 China Department of Diagno.tic and Interventional Radiology The Sixth Affiliated People’s Hospital shanghai Jiao Tong University shanghai 200233 China Department of Gastroenterology The Sixth Af��liated People’s HospitalShanghai Jiao Tong UniversityShanghai 200233China

AIM: To compare the efficacy of self-expanding metallic stents (SEMSs) for the long-term clinical treatment of achalasia. METHODS: Ninety achalasic patients were treated with a temporary SEMS with a diameter of 20 mm (n = 30, group A), 25 mm (n = 30, group B) or 30 mm (n = 30, group C). Data on clinical symptoms, complications and treatment outcomes were collected, and follow-up was made at 6 mo and at 1, 3-5, 5-8, 8-10 and > 10 years, ***: Stent placement was successful in all patients. Although chest pain occurrence was high, stent migration was less in group C than in groups A and B. The clinical remission rate at 5-8, 8-10 and > 10 years in group C was higher than that in the other two groups. The treatment failure rate was lower in group C (13%) than in groups A (53%) and B (27%). SEMSs in group C resulted in reduced dysphagia scores and lowered esophageal sphincter pressures, as well as no.mal levels of barium height and width during all the follow-up time periods. Conversely, these parameters increased over time in groups A and B. The primary patency in group C was longer than in groups A and B. CONCLUSION: A temporary SEMS with a diameter of 30 mm is associated with a superior long-term clinical efficacy in the treatment of achalasia compared with a SEMS with a diameter of 20 mm or 25 mm.

关键词： Achalasia Dysphagia Self-expanding metallic stents Comparison

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Comparison of different intervention procedures in benign stricture of gastrointestinal tract

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World Journal of Gastroenterology 2004年第3期10卷 410-414页

作者： Ying-ShengCheng Ming-HuaLi Wei-XiongChen Ni-WeiChen Qi-XinZhuang Ke-ZhongShang DepartmentofRadiology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China DepartmentofGastroenterology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China DepartmentofRadiology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China

AIM:To determine the most effective intervention procedure by evaluation of mid and long-term therapeutic efficacy in patients of stricture of the gastrointestinal tract (GTT). METHODS:Different intervention procedures were used to treat benign stricture of GIT in 180 patients including pneumatic dilation (group A,n=80),permanent (group B, n=25) and temporary (group C,n=75) placement of expandable metallic stents. RESULTS:The diameters of the strictured GIT were significantly greater after the treatment of all procedures employed (P<0.01).For the 80 patients in group A,160 dilations were performed (mean,2.0 times per patient). Complications in group A included chest pain (n=20),reflux (n=16),and bleeding (n=6).Dysphagia relapse occurred in 24(30%) and 48 (60%) patients respectively during 6-and- 12 momth follow-up periods in group *** group B,25 uncovered or partially covered or antireflux covered expandable metallic stents were placed permantly, complications included chest pain (n=10),reflux (n=15), bleeding (n=3),and stent migration (n=4),and dysphagia relapse occurred in 5 (20%) and 3 patients (25%) during the 6-and-12 month follow-up periods,*** group C,the partially covered expandable metallic stents were temporarily placed in 75 patients and removed after 3 to 7 days via gastroscope,complications including chest pain (n=30),reflux (n=9),and bleeding (n=12),and dysphagia relapse occurred in 9 (12%) and 8 patients (16%) during the 6-and-12 month follow-up periods,*** placement and withdrawal of stents were all successfully *** follow-up of all patients lasted for 6 to 96 months (mean 45.3±18.6 months). CONCLUSION:The effective procedures for benign GIT stricture are pneumatic dilation and temporary placement of partially-covered expandable metallic *** placement of partially-covered expandable metallic stents is one of the best methods for benign GIT strictures in mid and long-term therapeutic efficacy.

关键词： Dilatation Stents Adolescent Adult Aged Child Comparative Study Female Gastric Outlet Obstruction Humans Intestinal Obstruction Male Middle Aged Research Support, no.-U.S. Gov't

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Research progress of heat stroke during 1989–2019: A bibliometric analysis

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Military medical Research 2021年第3期8卷 384-394页

作者： De-Meng Xia Xu-Ren Wang Pan-Yu Zhou Tian-Le Ou Lei Su Shuo-Gui Xu Department of Emergency Changhai Hospitalthe Naval Medical UniversityShanghai 200433China Nursing College The Naval Medical UniversityShanghai 200433China Department of Clinical Medicine The Naval Medical UniversityShanghai 200433China Department of Intensive Care Unit General Hospital of Southern Theater CommandGuangzhou 510010China

Background: Heat stroke(HS) is an acute physical disorder that is associated with a high risk of organ dysfunction and even death. HS patients are usually treated symptomatically and conservatively;however, there remains a lack of specific and effective drugs in clinical practice. An analysis of publication contributions from institutions, journals and authors in different countries/regions was used to study research progress and trends regarding ***: We extracted all relevant publications on HS between 1989 and 2019 from Web of Science. Using the Statistical Package for Social Science(SPSS, version 24) and the software GraphPad Prism 8, graphs were generated and statistical analyses were performed, while VOSviewer software was employed to visualize the research trends in HS from the perspectives of co-occurring ***: As of April 14, 2020, we identified 1443 publications with a citation frequency of 5216. The United States accounted for the largest number of publications(36.2%) and the highest number of citations(14,410), as well as the highest H-index at 74. Although the sum of publications from China ranked second, there was a contradiction between the quantity and quality of publications. Furthermore, Medicine & Science in Sports & Exercise published the most papers related to HS, with Lin MT publishing the most papers in this field(112), while the review by Kno.hel JP received the highest citation frequency at 969. The keyword heat-stress appeared most recently, with an average appearing year of 2015.5. In the clinical research cluster, exertional heat-stroke was determined to be the hotspot, while ambient-temperature and heat waves were the new trends in the epidemiological research ***: Corresponding to this important field, while the contributions of the publications from the United States were significant, the mismatch between the quantity and quality of publications from China must be examined. Moreover, it is hypothesized

关键词： Heat stroke Publications Citation frequency

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Temporary partially-covered metal stent insertion in benign esophageal stricture

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World Journal of Gastroenterology 2003年第10期9卷 2359-2361页

作者： Ying-ShengCheng Ming-HuaLi Wei-XiongChen Ni-WeiChen Qi-XinZhuang Ke-ZhongShang DepartmentofRadiology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China DepartmentofGastroenterology SixthPeople’sHospitalShanghaiJiaotongUniversityShanghai200233China

AIM: To study the therapeutic efficacy of temporary partiallycovered metal stent insertion on benign esophageal ***: Temporary partially-covered metal stent was inserted in 83 patients with benign esophageal stricture. All the patients had various dysphagia ***: Insertion of 85 temporary partially-covered metal stents was performed successfully in 83 patients with benign esophageal stricture and dysphagia was effectively remitted in all the 83 cases. The dysphagia score was 3.20±0.63(mean±SD) and 0.68±0.31 before and after stent insertion,and 0.86±0.48 after stent removal. The mean diameter of the strictured esophageal lumen was 3.37±1.23 mm and 25.77±3.89 mm before and after stent insertion, and 16.15±2.96 mm after stent removal. Follow-up time was from 1 week to 96 months (mean 54.26±12.75 months). The complications were chest pain (n=37) after stent insertion,and bleeding (n=12) and reflux (n=13) after stent ***: Temporary partially-covered metal stent insertion is one of the best methods for treatment of benign esophageal stricture.

关键词：良性食管狭窄支架植入术并发症临床研究胸痛

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Selection and evaluation of three interventional procedures for achalasia based on long-term follow-up

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World Journal of Gastroenterology 2003年第10期9卷 2370-2373页

作者： Ying-ShengCheng, Ming-huaLi Wei-XiongChen Ni-WeiChen Qi-XinZhuang Ke-ZhongShang DepartmentofRadiology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China DepartmentofGastroenterology SixthPeople’sHospitalShanghaiJiaotongUniversityShanghai200233China

AIM: To determine the best method out of the three types of interventional procedure for achalasia based on a longterm ***: The study cohort was comprised of 133 patients of achalasia. Among them, 60 patients were treated under fluoroscopy with pneumatic dilation (group A), 8 patients with permanent uncovered or antireflux covered metal stent dilation (group B), and 65 patients with temporary partially covered metal stent dilation (group C).RESULTS: One hundred and thirty dilations were performed on the 60 patients of group A (mean 2.2 times per case).The mean diameter of the strictured cardia was 3.3±2.1 mm before dilation and 10.6±3.8 mm after dilation. The mean dysphagia score was 2.7±1.4 before dilation and 0.9±0.3after dilation. Complications in group A were chest pain (n=30), reflux (n=16), and bleeding (n=6). Thirty-six patients (60 %) in group A exhibited dysphagia relapse during a 12-month follow-up, and 45 patients (90 %) out of 50 exhibited dysphagia relapse during a 36-month followup. Five uncovered and 3 antireflux covered expandable metal stents were permanently placed in the 8 patients of group B. The mean diameter of the strictured cardia was 3.4±1.9 mm before dilation and 19.5±1.1 mm after *** mean dysphagia score was 2.6±1.3 before dilation and 0.4±0.1 after dilation. Complications in group B were chest pain (n=6), reflux (n＝5), bleeding (n=3), and hyperplasia of granulation tissue (n=3). Four patients (50 %) in group B exhibited dysphagia relapse during a 12-month followup, and 2 case (66.7 %) out of 3 patients exhibited dysphagia relapse during a 36-month follow-up. Sixty-five partially covered expandable metal stents were temporarily placed in the 65 patients of group C and withdrawn after 3-7 days via gastroscopy. The mean diameter of the strictured cardia was 3.3±2.3 mm before dilation and 18.9±3.5 mm after dilation. The mean dysphagia score was 2.4±1.3 before dilation and 0.5±0.2 after dilation. Complications in group C

关键词：失弛缓症干预措施随访支架置入术临床特点

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Follow-up evaluation for benign stricture of upper gastrointestinal tract with stent insertion

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World Journal of Gastroenterology 2003年第11期9卷 2609-2611页

作者： Ying-ShengCheng Ming-HuaLi Wei-XiongChen Qi-XinZhuang Ni-WeiChen Ke-ZhongShang DepartmentofRadiology SixthPeople'sHospitalShanghaiJiaotongUniversityShanghai200233China DepartmentofGastroenterology SixthPeople’sHospitalShanghaiJiaotongUniversityShanghai200233China

AIM: To determine the best mothod for benign stricture of the upper gastrointestinal tract (UGIT) with stent insertion by follow-up ***: A total of 110 stents insertions were performed in 110 cases of benign stricture of the UGIT. Permanent (group A) and temporary (group B) placement of an expandable metal stent in 30 cases and 80 cases respectively. All cases were completed under ***: In group A, 30 uncovered or antireflux covered or partially covered expandable metal stents were placed permanently. In group A, 5 cases (16.7 %) in 3-months, 5 cases (20.0 %) in 6-months, 6 cases (25 %) in the 1st year,6 cases (50 %) in the 3rd year, and 4 cases (80 %) in the 5th year exhibited dysphagia relapse. In group B, a partiallycovered expandable metal stent was temporarily placed in each patient and removed after 3-7 days via ***-up data in this group showed that 8 cases (7.5 %) in 3-months, 9 cases (12.0 %) in 6-months, 10 cases (15.4 %) in the 1st year, 6 cases (20 %) in the 3rd year, and 3 cases (25 %) in the 5th year exhibited dysphagia relapse. The placement and withdrawal of all stents were all performed successfully. The follow-up of all cases lasted for 3-99 months (mean 41.6±19.7 months).CONCLUSION: The best mothod for benign stricture of UGIT with stent insertion is temporary placement of a partially-covered expandable metal stent.

关键词：上消化道狭窄支架植入术良性狭窄临床研究

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Complications of stent placement for benign stricture of gastrointestinal tract

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World Journal of Gastroenterology 2004年第2期10卷 284-286页

AIM:To observe the frequent complications of stent placement for stricture of the gastrointestinal tract and to find proper ***:A total number of 140 stents were inserted in 138 patients with benign stricture of the gastrointestinal *** procedure was cornpleted under fluoroscopy in all of the ***:Stents were successfully placed in all the 138 *** occurred in 23 patients (16.7%),slight or dull pains were found in 21 patients and severe chest pain in 2 *** the former type of pain,the patients receivedonly analgesia or even no.treatment,while peridural anesthesics was conducted for the latter condition. Reflux occurred in 16 of these patients (11.6%) after stent *** was managed by common antireflux procedures. Gastrointestinal bleeding occurred in 13 patients (9.4%),and was treated by *** of the gastrointestinal tract occurred in 8 patients (5.8%),and was apparently associated with hyperplasia of granulation *** 2 patients,the second stent was placed under X-ray *** granulation tissue was removed by cauterization through hot-no.e therapy under gastroscope guidance in 3 patients,and surgical reconstruction was performed in ano.her 3 patients. Stent migration occurred in 5 patients (3.6%),and were extracted with the aid of a ***-bolus obstruction was encountered in 2 patients (1.4%) and was treated by endoscope *** perforation occurred in all ***:Frequent complications after stent placement for benign stricture of the gastrointestinal tract include pain,reflux,bleeding,resteno.is,stent migration and food-bolus *** can be treated by drugs,the second stent placement or gastroscopic procedures according to the specific conditions.

关键词：胃肠道良性狭窄支架置入术并发症 X线监测介入治疗

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