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A TRUST-REGION METHOD FOR SOLVING TRUNCATED COMPLEX SINGULAR VALUE DECOMPOSITION

Journal of Computational Mathematics 2024年第4期42卷 999-1031页

作者： Jiaofen Li Lingchang Kong Xuefeng Duan Xuelin Zhou Qilun Luo School of Mathematics and Computing science Guangxi Colleges and Universities Key Laboratory of Data Analysis and ComputationGuangxi Key Laboratory of Automatic Detecting Technology and InstrumentsGuilin University of Electronic TechnologyCenter for Applied Mathematics of Guangxi(GUET)Guilin 541004China School of Mathematical sciences South China Normal UniversityGuangzhou 510000China School of Mathematics and Computing science Guilin University of Electronic TechnologyGuilin 541004China School of Mathematics and Computing science Guangxi Colleges and Universities Key Laboratory of Data Analysis and ComputationGuilin University of Electronic TechnologyCenter for Applied Mathematics of Guangxi(GUET)Guilin 541004China School of Mathematics and Statistics Yunan UniversityKunming 650000China

The truncated singular value decomposition has been widely used in many areas of science including engineering,and statistics,*** this paper,the original truncated complex singular value decomposition problem is formulated as a Riemannian optimiza-tion problem on a product of two complex Stiefel manifolds,a practical algorithm based on the generic Riemannian trust-region method of Absil et *** presented to solve the underlying problem,which enjoys the global convergence and local superlinear conver-gence *** experiments are provided to illustrate the efficiency of the proposed *** with some classical Riemannian gradient-type methods,the existing Riemannian version of limited-memory BFGS algorithms in the MATLAB toolbox Manopt and the Riemannian manifold optimization library ROPTLIB,and some latest infeasible methods for solving manifold optimization problems,are also provided to show the merits of the proposed approach.

关键词： Truncated singular value decomposition Riemannian optimization Trust-region method

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Topological Confinement in Reversibly Interlocked Polymer Networks

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Chinese Journal of Polymer science 2024年第2期42卷 133-140,I0004页

作者： Wan-Ting Dai Zhen-Hua Xie Yu-Bin Ke Yang You Min-Zhi Rong Ming-Qiu Zhang Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education GD HPPC LabIGCMESchool of ChemistrySun Yat-sen UniversityGuangzhou510275China Spallation Neutron Source science Center China Spallation Neutron SourceDongguan523803China Institute of High Energy Physics Chinese Academy of SciencesBeijing100049China College of Materials and Metallurgy Guizhou UniversityGuiyang550025China

Recently, we reported a series of reversibly interlocked polymer networks(RILNs), whose mechanical robustness and functionalities improvement was believed to be derived from topological interlocking of two sub-networks, although the direct evidence for the deduction is still lacking. Herein, a specially-designed RILNs system, in which the inter-component hydrogen bonds can be shielded as needed, was prepared and used to study the micro-structures of RILNs, aiming to verify the existence of mechanical interlocking in RILNs. By changing the pH of the swelling solvent, the effect exerted by the inter-component non-covalent bonds was eliminated, so detailed information of the networks structure was exposed. The small angle X-ray scattering(SAXS) and small-angle neutron scattering(SANS) results indicated that swelling-induced structural evolution of the two sub-networks mutually affected each other, even when the inter-component hydrogen bonds were absent, proving the presence of topological interlocking. The findings may help to draw a more accurate physical image and reveal the detailed structureproperty relationship of RILNs.

关键词： Reversibly interlocked polymer networks Small angle X-ray scattering Small-angle neutron scattering Topological confinement

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MAPK4 facilitates angiogenesis by inhibiting the ERK pathway in non-small cell lung cancer

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Cancer Innovation 2024年第3期3卷 33-48页

作者： Jing Chen Jing Yang Yufang Liu Xu Zhao Juanjuan Zhao Lin Tang Mengmeng Guo Ya Zhou Chao Chen Dongmei Li Zhenke Wen Guiyou Liang Lin Xu Special Key Laboratory of Gene Detection&Therapy of guizhou province ZunyiGuizhouChina Department of Immunology Zunyi Medical UniversityZunyiGuizhouChina Department of Medical Physics Zunyi Medical UniversityZunyiGuizhouChina Institute of Biomedical Soochow UniversitySuzhouJiangsuChina Department of Cardiovascular Surgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhouChina

Background:Angiogenesis plays an important role in the occurrence and development of non-small cell lung cancer(NSCLC).The atypical mitogen-activated protein kinase 4(MAPK4)has been shown to be involved in the pathogenesis of various ***,the potential role of MAPK4 in the tumor angiogenesis of NSCLC remains ***:Adult male C57BL/6 wild-type mice were randomly divided into the control group and p-siMAPK4 intervention group,*** cell proliferation was analyzed with flow cytometry and immunofluorescence *** vascular density in tumor mass was analyzed by immuno-fluorescence *** expressions of MAPK4 and related signaling molecules were detected by western blot analysis and immunofluorescence staining,and so ***:We found that the expression of MAPK4,which was dominantly expressed in local endothelial cells(ECs),was correlated with tumor angiogenesis of ***,MAPK4 silencing inhibited the proliferation and migration abilities of human umbilical vein ECs(HUVECs).QKHZC-2020-4Y156,QKH-JC-2018-1428,QKH-RC-2019-5612;Collaborative Innovation Center of Chinese Ministry of Education,Grant/Award Number:2020-39;program for science and technology Joint Fund Project in Zunyi science and technology Bureau and Zunyi Medical University,Grant/Award Numbers:ZSKH-RPT-2020-6,ZSKH-HZ-2021-193;Graduate Research Fund of Zunyi Medical University,Grant/Award Number:2023-ZYK-171 Global gene analysis showed that MAPK4 silencing altered the expression of multiple genes related to cell cycle and angiogenesis pathways,and that MAPK4 silencing increased transduction of the extracellular regulated protein kinases 1/2(ERK1/2)pathway but not Akt and c-Jun n-terminal kinase *** analysis showed that MAPK4 silencing inhibited the proliferation and migration abilities of HUVECs cultured in tumor cell supernatant,which was accompanied with increased transduction of the ERK1/2 *** data analysis suggested that the

关键词： angiogenesis endothelial cell MAPK4 NSCLC p-ERK1/2

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Screening for Antioxidant Phenolic Compounds from Polygonum capitatum

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Medicinal Plant 2024年第4期15卷 1-3,10页

作者： Yan LIN State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical UniversityGuiyang 55000China University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in guizhou province School of Pharmaceutical SciencesGuizhou Medical UniversityGuiyang 55000China

[Objectives]To discover antioxidant natural products from the famous Hmong medicinal plant Polygonum capitatum.[Methods]The antioxidant activities of the isolated components were evaluated by ABTS and DPPH assays.[Results]A total of 27 free phenolics were isolated form *** the in vitro antioxidant potential of these components was evaluated according to the DPPH and ABTS radical scavenging *** them,five compounds(13,14,17,23,and 25)showed most significant ABTS radical-scavenging activity(IC 50 values of 3.81-15.09μg/mL).And 12 components(1,2,6,7,9,12,13,14,16,17,23,and 25)showed notable radical scavenging activity against DPPH(inhibition rates>88%).[Conclusions]Most of the above bioactive compounds were reported for the first time.

关键词： Polygonum capitatum Phenolic compounds Antioxidant activity

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Engineering fibrillar morphology for highly efficient organic solar cells

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Journal of Semiconductors 2024年第2期45卷 7-9页

作者： Chengcheng Xie Bin Zhang Menglan Lv Liming Ding Engineering Research Center for Energy Conversion and Storage technology of guizhou School of Chemistry and Chemical EngineeringGuizhou UniversityGuiyang 550025China Center for Excellence in Nanoscience(CAS) Key Laboratory of Nanosystem and Hierarchical Fabrication(CAS)National Center for Nanoscience and TechnologyBeijing 100190China

The power conversion efficiency(PCE)for single-junction organic solar cells(OSCs),wherein the photoactive layer is a typical bulk-heterojunction containing donor and acceptor materials,has surpassed 19%[1−4].The advance is ascribed to the development of Y-series non-fullerene acceptors(NFAs)[5,6]and polymer donors[7−13],and the refined control of the blend film morphology.

关键词： morphology refined donor

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The natural sources,extraction,and nephroprotective function of oleanolic acid and ursolic acid:a review

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Food and Health 2024年第3期6卷 20-32页

作者： Wen-Ying Chen Hong-Wei Wang Song Yao Yao Zhou Shuang-Chao Liu Xiao Li Shen School of Public Health Zunyi Medical UniversityZunyi 563000GuizhouChina Key Laboratory of Maternal&Child Health and Exposure science of guizhou Higher Education Institutes Zunyi 563000GuizhouChina

Oleanolic acid(OA)and ursolic acid(UA)are commonly present in the cuticular wax of many edible fruits and medicinal *** and UA belong to the group of bioactive pentacyclic triterpenoids,exhibiting a wide range of beneficial effects including protection for the kidneys,liver,heart,gastrointestinal tract,and spinal ***,OA and UA exhibit antioxidant,anti-ferroptotic,anti-apoptotic,anti-inflammatory,anti-tumor,anti-viral,anti-diabetic,anti-microbial,anti-parasitic,analgesic,wound-healing,hypolipidemic,and hypoglycemic properties,often without notable side *** to the extensive array of their positive functions,it is not feasible to thoroughly cover all aspects in this ***,the primary focus lies on reviewing the natural sources,extraction,and nephroprotective properties of OA and *** summarize,current literatures highlight the nephroprotective mechanisms of OA and UA,primarily involving inhibiting oxidative stress,endoplasmic reticulum stress,glycative stress,dyslipidemia,inflammation,apoptosis,pyroptosis,and renal fibrosis,promoting diuresis,as well as fine-tuning autophagy.

关键词： oleanolic acid ursolic acid natural sources nephroprotective nephrotoxicity

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A Machine Learning Made Catalog of FR-Ⅱ Radio Galaxies from the FIRST Survey

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Research in Astronomy and Astrophysics 2024年第3期24卷 266-282页

作者： Bao-Qiang Lao Xiao-Long Yang Sumit Jaiswal Prashanth Mohan Xiao-Hui Sun Sheng-Li Qin Ru-Shuang Zhao School of Physics and Astronomy Yunnan UniversityKunming 650091.China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030.China School of Physics and Electronic science Guizhou Normal UniversityGuiyang 550001China

We present an independent catalog(FRIIRGcat)of 45,241 Fanaroff–Riley TypeⅡ(FR-Ⅱ)radio galaxies compiled from the Very Large Array Faint Images of the Radio Sky at Twenty-centimeters(FIRST)survey and employed the deep learning *** them,optical and/or infrared counterparts are identified for 41,425 FR-Ⅱ*** catalog spans luminosities 2.63×10^(22)≤L_(rad)≤6.76×10^(29)W Hz^(-1)and redshifts up to z=*** spectroscopic classification indicates that there are 1431 low-excitation radio galaxies and 260 high-excitation radio *** the spectroscopically identified sources,black hole masses are estimated for 4837 FR-Is,which are in 10^(7.5)■M_(BH)■10^(9.5)M_(⊙).Interestingly,this catalog reveals a couple of giant radio galaxies(GRGs),which are already in the existing GRG catalog,confirming the efficiency of this FR-I ***,284new GRGs are unveiled in this new FR-I sample;they have the largest projected sizes ranging from 701 to1209 kpc and are located at redshifts 0.31

关键词： radio continuum galaxies-galaxies active-galaxies jets-galaxies statistics

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System Reliability Analysis of Reservoir Landslides: Insights from Long-Term Reservoir Operation

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Journal of Earth science 2024年第05期 1583-1593页

作者： Kang Liao Yiping Wu Fasheng Miao Faculty of Geosciences and Engineering Southwest Jiaotong University Faculty of Engineering China University of Geosciences

The reservoir operation awakens numerous landslides with multiple sliding surfaces known as reservoir landslides, and the systematic stability analysis for such landslides is becoming increasingly urgent. Taking the Majiagou landslide as an example, this paper analyses the comprehensive performance of the landslide from a probabilistic point of view. Under a reservoir operation cycle, a series of numerical analyses are carried out to simulate the migration of the seepage field, then the dynamic stability of the landslide is quantified accordingly. Subsequently, the wetting-drying cycles test is used to model the weakening of strength parameters in hydro-fluctuation belt under the long-term reservoir operation. Considering the weakening effect of long-term reservoir operation on the hydrofluctuation belt, the system reliability is evaluated using the Ditlevsen ' s bounds. The results suggest that the reservoir operation can affect the stability of the landslide by changing the seepage field. The system failure probability gradually rises as the number of wetting-drying cycles increases. Compared with conventional probabilistic analysis that calculates the failure probability of each sliding surface mechanically, analyzing the landslide in terms of system reliability can effectively narrow the failure probability range, which provides an insightful idea for evaluating the systematic stability of analogous reservoir landslides.

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The significance of long non-coding RNAs in the pathogenesis,diagnosis and treatment of inflammatory bowel disease

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Precision Clinical Medicine 2024年第1期7卷 34-53页

作者： Fei Jiang Min Wu Rongpeng Li Jiangsu province Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells School of Life SciencesJiangsu Normal UniversityXuzhou 221000China Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221000China Drug Discovery Section Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325000China Department of Neurology Medical College of WisconsinMilwaukeeWI 53226USA

Inflammatory bowel diseases(IBD)are a group of chronic relapsing gastrointestinal inflammatory diseases with significant global *** the pathomechanism of IBD has been extensively investigated,several aspects of its pathogenesis remain *** non-coding RNAs(lncRNAs)are transcripts with more than 200 nucleotides in length that have potential protein-coding *** play important roles in biological processes such as epigenetic modification,transcriptional regulation and posttranscriptional *** this review,we summarize recent advances in research on IBD-related lncRNAs from the perspective of the overall intestinal microenvironment,as well as their potential roles as immune regulators,diagnostic biomarkers and therapeutic targets or agents for IBD.

关键词： lncRNAs inflammatory bowel diseases intestinal barrier intestinal microenvironment immune regulator diagnostic biomarker therapeutic target

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Application of Natural Medicinal Plants Active Ingredients in Oral Squamous Cell Carcinoma

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Chinese Journal of Integrative Medicine 2024年第9期30卷 852-864页

作者： REN Qun-li LI Xiao-lan TIAN Tian LI Shuang SHI Rong-yi WANG Qian ZHU Yuan WANG Miao HU Huan LIU Jian-guo School of Stomatology Zunyi Medical UniversityZunyiGuizhou Province563000China Microbial Resources and Drug Development Key Laboratory of guizhou Tertiary Institution Zunyi Medical UniversityZunyiGuizhou Province563000China School of Basic Medicine Zunyi Medical UniversityZunyiGuizhou Province563000China

Oral squamous cell carcinoma(OSCC)is the most common malignant cancer of the head and neck,with high morbidity and mortality,ranking as the sixth most common cancer in the *** treatment of OSCC is mainly radiotherapy,chemotherapy and surgery,however,the prognosis of patients is still poor and the recurrence rate is *** paper reviews the range of effects of natural medicinal plant active ingredients(NMPAIs)on OSCC cancer,including the types of NMPAIs,anti-cancer mechanisms,involved signaling pathways,and clinical *** NMPAIs include terpenoids,phenols,flavonoids,glycosides,alkaloids,coumarins,and volatile *** active ingredients inhibit proliferation,induce apoptosis and autophagy,inhibit migration and invasion of OSCC cells,and regulate cancer immunity to exert anti-cancer *** mechanism involves signaling pathways such as mitogen-activated protein kinase,phosphatidylinositol 3 kinase/protein kinase B,nuclear factor kappa B,miR-22/WNT1/β-catenin and Nrf2/***,NMPAIs can inhibit the growth of OSCC,and the combined drug is more *** medicinal plants are promising candidates for the treatment of OSCC.

关键词： natural medicinal plant active ingredients oral squamous cell carcinoma mechanism signaling pathway review

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