检索结果-南通市图书馆

Chinese Journal of Integrative Medicine 2024年第4期30卷 379-384页

作者： XIN Li TAN Guo-yao ZHANG Qiang ZHANG Qun Good Clinical Practice Development Guangdong Provincial Key Laboratory of Bone and Joint Degeneration DiseasesThe Third Affiliated Hospital of Southern Medical UniversityGuangzhou(510630)China Department of Pharmacy Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou(510120)China

Phellodendron(PN)species,traditionally used in Chinese medicine for centuries,hold promise as a potential treatment for osteoporosis(OP)and osteoarthritis(OA)due to their bioactive *** bioactive compounds,including berberine and palmatine,exhibit anti-inflammatory,antioxidant,and bone-protective properties,contributing to their potential therapeutic benefits in promoting bone health and preventing bone ***,challenges such as the need for standardized preparation and dosing,limited clinical studies,and potential interactions with other medications hinder their clinical ***,the rich history of PN species in Chinese medicine provides a promising foundation for future investigation into their potential as alternative treatments for OP and *** research is needed to fully understand the underlying mechanisms of action and explore the clinical implications of PN for bone health.

关键词： Phellodendron species bone health osteoporosis osteoarthritis review

Effects of Lycium barbarum polysaccharide on cytokines in adolescents with subthreshold depression:a randomized controlled study

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第9期19卷 2036-2040页

作者： Xiaoyue Li Tao Liu Xuan Mo Runhua Wang Xueyan Kong Robin Shao Roger S.Mclntyre Kwok-Fai So Kangguang Lin Department of Affective Disorders The Affiliated Brain Hospital of Guangzhou Medical University(Guangzhou Huiai Hospital)GuangzhouGuangdong ProvinceChina Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Psychiatry The Fifth Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Mood Disorders Psychopharmacology Unit Poul Hansen Family Centre for DepressionUniversity Health NetworkTorontoONCanada Department of Psychiatry University of TorontoTorontoONCanada Brain and Cognition Discovery Foundation TorontoCanada Ministry of Education Joint International Research Laboratory of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Strong evidence has accumulated to show a correlation between depression symptoms and inflammatory ***,anti-inflammatory treatment has shown partial effectiveness in alleviating depression *** barbarum polysaccharide(LBP),derived from Goji berries,exhibits notable antioxidative and anti-inflammatory *** our recent double-blinded randomized placebo-controlled trial,we found that LBP significantly reduced depressive symptoms in adolescents with subthreshold *** is presumed that the antidepressant effect of LBP may be associated with its influence on inflammatory *** the double-blinded randomized controlled trial,we enrolled 29 adolescents with subthreshold depression and randomly divided them into an LBP group and a placebo *** the LBP group,adolescents were given 300 mg/d LBP.A 6-week follow up was completed by 24 adolescents,comprising 14 adolescents from the LBP group(15.36±2.06 years,3 men and 11 women)and 10 adolescents from the placebo group(14.9±1.6 years,2 men and 8 women).Our results showed that after 6 weeks of treatment,the interleukin-17A level in the LBP group was lower than that in the placebo *** analysis showed that LBP reduced the correlations and connectivity between inflammatory factors,which were associated with the improvement in depressive *** findings suggest that 6-week administration of LBP suppresses the immune response by reducing interleukin-17A level,thereby exerting an antidepressant effect.

关键词： adolescents cytokines efficacy Goji berry inflammatory responses interleukin-17A Lycium barbarum polysaccharide randomized controlled study subthreshold depression

Precipitates Generation Mechanism and Surface Quality Improvement for Aluminum Alloy 6061 in Diamond Cutting

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of technology(Materials science) 2024年第1期39卷 150-159页

作者：王海龙 DENG Wenping 王素娟 State Key Laboratory of Precision Electronic Manufacturing technology and Equipment Guangdong University of TechnologyGuangzhou 510006China Guangdong Provincial Key Laboratory of Micro-Nano Manufacturing technology and Equipment School of Electromechanical EngineeringGuangdong University of TechnologyGuangzhou 510006China

To improve the surface quality for aluminum alloy 6061(Al6061) in ultra-precision machining, we investigated the factors affecting the surface finish in single point diamond turning(SPDT)by studying influence of the precipitates generation of Al6061 on surface integrity and surface *** on the Johnson-Mehl-Avrami solid phase transformation kinetics equation, theoretical and experimental studies were conducted to build the relationship between the aging condition and the type, size and number of the precipitates for Al6061. Diamond cutting experiments were conducted to machine Al6061 samples under different aging conditions. The experimental results show that, the protruding on the chip surface is mainly Mg_(2)Si and the scratches on the machined surface mostly come from the iron-containing phase(α-, β-AlFeSi).Moreover, the generated Mg_(2)Si and α-, β-AlFeSi affect the surface integrity and the diamond turned surface roughness. Especially, the achieved surface roughness in SPDT is consistent with the variation of the number of AlFeSi and Mg_(2)Si with the medium size(more than 1 μm and less than 2 μm) in Al6061.

关键词： Al6061 precipitates aging treatment diamond cutting surface roughness

DNA Methylation Variation Is Identified in Monozygotic Twins Discordant for Congenital Heart Diseases

在线全文

学校读者我要写书评

暂无评论

Congenital Heart Disease 2024年第2期19卷 247-256页

作者： Shuliang Xia Huikang Tao Shixin Su Xinxin Chen Li Ma Jianru Li Bei Gao Xumei Liu Lei Pi Jinqing Feng Fengxiang Li Jia Li Zhiwei Zhang Guangdong Provincial People’s Hospital Southern Medical UniversityGuangzhou510100China Department of Cardiovascular Surgery Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatric Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of South China Structural Heart DiseaseGuangzhou510100China Clinical Physiology Laboratory Institute of PediatricsGuangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Key Laboratory of Research in Structural Birth Defect DiseaseGuangzhou510623China Department of Echocardiogram Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhou510623China Department of Pediatrics Washington University School of MedicineSt.LouisMO63130USA Clinical Biological Resource Bank of guangzhou Women and Children’s Medical Center Guangzhou Medical UniversityGuangzhou510623China

Aims:Multiple genes and environmental factors are known to be involved in congenital heart disease(CHD),but epigenetic variation has received little ***(MZ)twins with CHD provide a unique model for exploring this *** order to investigate the potential role of Deoxyribonucleic Acid(DNA)methyla-tion in CHD pathogenesis,the present study examined DNA methylation variation in MZ twins discordant for CHD,especially ventricular septal defect(VSD).Methods and Results:Using genome-wide DNA methylation profiles,we identified 4004 differentially methylated regions(DMRs)in 18 MZ twin pairs discordant for CHD,and 2826 genes were *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis revealed a list of CHD-associated *** further investigate the role of DNA methylation in VSD,data from 7 pairs of MZ twins with VSD were *** identified 1614 DMRs corresponding to 1443 genes associated with arrhythmogenic right ventricular cardiomyopathy,cyclic guanosine monopho-sphate-protein kinase G(cGMP-PKG)signaling pathway by KEGG analysis,and cell-cell adhesion,calcium ion transmembrane transport by GO analysis.A proportion of DMR-associated genes were involved in calcium signaling *** methylation changes of calcium signaling genes might be related to VSD ***:CHD is associated with differential DNA methylation in MZ *** may be etiologically linked to DNA methylation,and methylation of calcium signaling genes may be involved in the development of VSD.

关键词： Congenital heart disease monozygotic twins methylation modification epigenetics

Modification of separators with neodymium oxide/graphene composite to enhance lithium-sulfur battery performance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第9期42卷 1730-1739,I0004页

作者： Liyuan Zheng Zhijun Zhu Yutong Kuai Qiaotong Huang Mingkun Zhang Yi Wang Aiju Li School of Chemistry South China Normal UniversityGuangzhou510006China Department of Mechanic and Electronic Engineering Zhongkai University of Agriculture and EngineeringGuangzhou510225China

Lithium-sulfur(Li-S) batteries have generated significant attention due to their high theoretical specific capacity and energy density among a host of energy storage power ***,the lithium polysulfide dissolution shuttle that occurs within Li-S batteries will lead to capacity deterioration and inadequate cycling *** the paper,we proposed a measure to deal with the above problems by modifying the separator with Nd_(2)O_(3)/graphene composite in Li-S ***'s special chemical properties and structural qualities make it an excellent choice for Li-S ***,Nd_(2)O_(3) has a strong binding affinity with lithium polysulfide due to its low electronegativity,which exhibits Lewis' s acidity and forms strong interactions with lithium polysulfide,which is strongly Lewis *** utilizing these advantageous properties,Li-S batteries assembling Nd_(2)O_(3)-decorated reduced graphite oxide modified polypropylene separators(Nd_(2)O_(3)/RGO/PP) demonstrate outstanding electrochemical performance,including a mere 0.0525% capacity attenuation rate under 2C during 1000 cycles and with exceptional rate performance of 614 mAh/g even at *** study presents valuable knowledge for effectively modifying separators using rare earth oxides to incorporate graphene,ultimately promoting the practical application of Li-S batteries.

关键词： Lithium-sulfur battery Rare earths Neodymium oxide Graphene Modified separator

Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第8期16卷 2724-2734页

作者： Song Fei Wei-Dong Wu Han-Shuo Zhang Shao-Jie Liu Dan Li Bo Jin Department of Thoracic and Cardiovascular Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Department of Gastrointestinal Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Neuroendocrine tumors(NETs)arise from the body’s diffuse endocrine *** primary adenocarcinoma of the colon and NETs of the duodenum(D-NETs)is a rare occurrence in clinical *** classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been *** SUMMARY We report the details of a case involving female patient with coexisting primary adenocarcinoma of the colon and a D-NET diagnosed by imaging and surgical *** tumors were treated by surgery and four courses of *** patient achieved a favorable clinical *** Coexisting primary adenocarcinoma of the colon and D-NET were diagnosed by imaging,laboratory indicators,and surgical *** resection com-bined with chemotherapy was a safe,clinically effective,and cost-effective treat-ment.

关键词： Neuroendocrine tumor of the duodenum Multiple primary tumors Colorectal cancer Endoscopic resection Case report

Optical edge-to-screw singularity state conversions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第8期12卷 1689-1695页

作者： HAOLIN LIN JUNHUI JIA GUOHUA LIU YANWEN HU ZHEN LI ZHENQIANG CHEN SHENHE FU Department of Optoelectronic Engineering Jinan UniversityGuangzhou 510632China Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications Guangzhou 510632China Guangdong Provincial Engineering Research Center of Crystal and Laser technology Guangzhou 510632China

Optical singularity states,which significantly affect propagation properties of light in free space or optical medium,can be geometrically classified into screw and edge *** different types of singularity states do not exhibit direct connection,being decoupled from each other in the absence of external *** we demonstrate a novel optical process in which a higher-order edge singularity state initially nested in the propagating Gaussian light field gradually involves into a screw singularity with a new-born topological charge determined by order of the edge *** considered edge state comprises an equal superposition of oppositely charged vortex and antivortex *** theoretically and experimentally realize this edge-to-screw conversion process by introducing intrinsic vortex–antivortex *** also present a geometrical representation for mapping this dynamical process,based on the higher-order orbital Poincaré*** this framework,the edge-to-screw conversion is explained by a mapping of state evolution from the equator to the north or south pole of the Poincaré*** demonstration provides a novel approach for manipulating singularity state by the intrinsic vortex–antivortex *** presented phenomenon can be also generalized to other wave systems such as matter wave,water wave,and acoustic wave.

关键词： interaction Poincaré wave

Prediction of surface settlement caused by synchronous grouting during shield tunneling in coarse-grained soils:A combined FEM and machine learning approach

在线全文

学校读者我要写书评

暂无评论

Underground Space 2024年第3期16卷 206-223页

作者： Chao Liu Zepan Wang Hai Liu Jie Cui Xiangyun Huang Lixing Ma Shuang Zheng School of Civil Engineering Guangzhou UniversityGuangzhou 510006China Guangdong Engineering Research Center for Underground Infrastructural Protection in Coastal Clay Areas Guangzhou UniversityGuangzhou 510006China Earthquake Engineering Research&Test Center Guangzhou UniversityGuangzhou 510006China CSCEC4 Civil Engineering Co. Ltd.Shenzhen 518052China

This paper presents a surrogate modeling approach for predicting ground surface settlement caused by synchronous grouting during shield tunneling *** proposed method combines finite element simulations with machine learning algorithms and introduces an intelligent optimization algorithm to invert geological parameters and synchronous grouting variables,thereby predicting ground surface settlement without conducting numerous finite element *** surrogate models based on the random forest algorithm are *** first is a parameter inversion surrogate model that combines an artificial fish swarm algorithm with random forest,taking into account the actual number and distribution of complex soil *** second model predicts surface settlement during synchronous grouting by employing actual cover-diameter ratio,inverted soil parameters,and grouting *** avoid changes to input parameters caused by the number of overlying soil layers,the dataset of this model is generated by the finite element model of the homogeneous soil *** surrogate modeling approach is validated by the case history of a large-diameter shield tunnel in Beijing,providing an alternative to numerical computation that can efficiently predict surface settlement with acceptable accuracy.

关键词： Shield tunnel Machine learning Synchronous grouting Surrogate modeling Surface settlement

Adsorption and activation of peroxymonosulfate on BiOCl for carbamazepine degradation: The role of piezoelectric effect

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第10期35卷 421-424页

作者： Cunjun Li Wencong Liu Xianlei Chen Liang Li Shenyu Lan Mingshan Zhu Zhoushan Institute of Calibration and Testing for Quality and technology Supervision Zhoushan 316012China School of Environment Jinan UniversityGuangzhou 511443China Department of Environmental science and Engineering Xi'an Jiaotong UniversityXi'an 710049China

The adsorption of peroxymonosulfate(PMS)is crucial for PMS activation in the heterogeneous advanced oxidation ***,the investigation of PMS adsorption on the piezocatalysts still remains *** this work,bismuth oxychloride(BiO Cl)nanosheets were prepared as the piezocatalysts for PMS activation under ultrasonic vibration to remove carbamazepine(CBZ)in aqueous *** to92.5%of CBZ was degraded for 40 min in Bi OCl piezo-activated PMS system with the reaction rate constant of 0.0741 min-1,being 1.63 times that of the sum of BiOCl piezocatalysis,BiOCl-activated PMS,and vibration-activated *** adsorption on the surface of BiOCl was specifically studied by comparing the microscopic structure change of the fresh and used Bi *** results suggested that the piezoelectric field of Bi OCl was able to promote the tight adsorption of PMS on the surface,thus facilitating the fast activation of PMS through electrons transfer to produce reactive species(HO·,SO_(4)·-,O_(2)·-,1O_(2)).This work presents an in-depth understanding for the role of piezoelectric effect on the adsorption and activation of PMS.

关键词： Peroxymonosulfate adsorption Peroxymonosulfate activation Electron transfer Biocl piezoelectricity Carbamazepine degradation

Antimicrobial Resistance Analysis and Whole-Genome Sequencing of Salmonella Isolates from Environmental Sewage — guangzhou City, Guangdong Province, China, 2022–2023

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2024年第13期6卷 254-260页

作者： Bihui Su Guanghong Du Shuiping Hou Zongqiu Chen Xiaoying Wu Gang He Jun Yuan Chaojun Xie Tuberculosis Management and Treatment Department Guangzhou Chest HospitalGuangzhou CityGuangdong ProvinceChina School of Public Health Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina guangzhou Center for Disease Control and Prevention Guangzhou CityGuangdong ProvinceChina Office of the Director Huadu District Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina

What is already known about this topic?S.1,4,[5],12:i:-and *** are emerging serotypes of Salmonella that require close monitoring for antimicrobial resistance and containment of their *** is added by this report?The study aimed to identify antimicrobial resistance genes(ARGs)in S.1,4,[5],12:i:-and *** strains isolated from environmental sewage in guangzhou City,Guangdong Province,China.A phylogenetic tree was constructed using single nucleotide polymorphism data to assess genetic relatedness among strains,offering insights for Salmonella infection outbreak investigations in the *** are the implications for public health practice?It is crucial to implement strategies,such as integrating different networks,to control the spread of drugresistant *** technologies must be utilized to disinfect sewage and eliminate *** food safety and proper sewage disinfection are essential to curb the dissemination of Salmonella.

关键词： Whole offering integrating