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Effects of cytoreductive surgery combined with hyperthermic perfusion chemotherapy on prognosis of patients with advanced gallbladder cancer

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2413-2422页

作者： Jin-Xiu Wu Rong Hua Xiang-Ji Luo Feng Xie Li Yao Department of Hepatobiliary-Pancreatic Surgery Punan Branch of Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200125China Department of Biliary-Pancreatic Surgery Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Biliary Tract Surgery Eastern Hepatobiliary Surgery HospitalSecondary Military Medical UniversityShanghai 200438China

BACKGROUND Gallbladder cancer(GC)is a common malignant tumor and one of the leading causes of cancer-related death *** is typically highly invasive,difficult to detect in the early stages,and has poor treatment outcomes,resulting in high mortality *** available treatment options for GC are relatively *** emerging treatment modality is hyperthermic intraperitoneal chemotherapy(HIPEC).HIPEC involves delivering heated chemotherapy directly into the abdominal *** combines the strategies of surgical tumor resection and localized chemotherapy administration under hyperthermic conditions,aiming to enhance the concentration and effectiveness of drugs within the local tumor site while minimizing systemic *** To determine the effects of cytoreductive surgery(CRS)combined with HIPEC on the short-term prognosis of patients with advanced *** Data from 80 patients treated at the Punan Branch of Renji Hospital,Shanghai Jiao Tong University School of Medicine between January 2018 and January 2020 were retrospectively *** control group comprised 44 patients treated with CRS,and the research group comprised 36 patients treated with CRS combined RESULTS The baseline data of the research and control groups were similar(P>0.05).Six days after surgery,the alanine aminotransferase,aspartate aminotransferase,total bilirubin,and direct bilirubin levels significantly decreased compared to the preoperative levels in both groups(P0.05).Similarly,the postoperative creatinine and blood urea nitrogen levels were significantly lower than the preoperative levels in both groups(P0.05).Furthermore,the research group had fewer postoperative adverse reactions than the control group(P=0.027).Finally,a multivariate Cox analysis identified the tumor stage,distant metastasis,and the treat

关键词： Gallbladder diseases Chemotherapy,Cancer,Regional Perfusion Gallbladder neoplasms Prognosis Regression analysis Survival rate

Building Morphological Characteristics and Their Effect on the Wind in Beijing

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Advances in Atmospheric sciences 2009年第6期26卷 1115-1124页

作者：苗世光李萍阳王晓云 Institute of Urban Meteorology China Meteorological Administration National Meteorological Center China Meteorological Administration Department of Integrated Observations China Meteorological Administration

An urban boundary layer model （UBLM） is improved by incorporating the effect of buildings with a sectional drag coefficient and a height-distributed canopy drag length scale. The improved UBLM is applied to simulate the wind fields over three typical urban blocks over the Beijing area with different height-towidth ratios. For comparisons, the wind fields over the same blocks are simulated by an urban sub-domain scale model resolving the buildings explicitly. The wind fields simulated from the two different methods are in good agreement. Then, two-dimensional building morphological characteristics and urban canopy parameters for Beijing are derived from detailed building height data. Finally, experiements are conducted to investigate the effect of buildings on the wind field in Beijing using the improved UBLM.

关键词： building morphological characteristics urban boundary layer model urban canopy model

Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome:a 15-year follow-up from a prospective cohort study

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Bone Research 2020年第1期8卷 107-114页

作者： Peixun Zhang Jia Li Huixin Liu Na Han Jiabao Ju Yuhui Kou Lei Chen Mengxi Jiang Feng Pan Yali Zheng Zhancheng Gao Baoguo Jiang Department of Orthopedics and Trauma Peking University People’s HospitalBeijingChina Department of Respiratory Medicine Peking University People’s HospitalBeijingChina Department of Clinical Epidemiology and Biostatistics Peking University People’s HospitalBeijingChina Department of Central Laboratory Peking University People’s HospitalBeijingChina Department of Education Peking University People’s HospitalBeijingChina Department of Radiology Peking University People’s HospitalBeijingChina

The most severe sequelae after rehabilitation from SARS are femoral head necrosis and pulmonary fibrosis. We performed a 15-year follow-up on the lung and bone conditions of SARS patients. We evaluated the recovery from lung damage and femoral head necrosis in an observational cohort study of SARS patients using pulmonary CT scans, hip joint MRI examinations, pulmonary function tests and hip joint function questionnaires. Eighty medical staff contracted SARS in 2003. Two patients died of SARS, and78 were enrolled in this study from August 2003 to March 2018. Seventy-one patients completed the 15-year follow-up. The percentage of pulmonary lesions on CT scans diminished from 2003(9.40 ± 7.83)% to 2004(3.20 ± 4.78)%(P < 0.001) and remained stable thereafter until 2018(4.60 ± 6.37)%. Between 2006 and 2018, the proportion of patients with interstitial changes who had improved pulmonary function was lower than that of patients without lesions, as demonstrated by the one-second ratio(FEV1/FVC%, t = 2.21, P = 0.04) and mid-flow of maximum expiration(FEF25%–75%, t = 2.76, P = 0.01). The volume of femoral head necrosis decreased significantly from 2003(38.83 ± 21.01)% to 2005(30.38 ± 20.23)%(P = 0.000 2), then declined slowly from 2005 to 2013(28.99 ± 20.59)% and plateaued until 2018(25.52 ± 15.51)%. Pulmonary interstitial damage and functional decline caused by SARS mostly recovered, with a greater extent of recovery within 2 years after rehabilitation. Femoral head necrosis induced by large doses of steroid pulse therapy in SARS patients was not progressive and was partially reversible.

关键词： doses consequences slowly

Real-time ultrasound-guided external intracerebral hemorrhage drain placement

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Military Medical Research 2021年第1期8卷 138-140页

作者： Cong Feng Sai Huang Li Chen Xuan Zhou Li-Li Wang Fa-Qin Lv Tan-Shi Li Department of Emergency the First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Hematology the First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Ultrasound Hainan HospitalChinese PLA General HospitalSanya 572000China

We report a new minimally invasive technique utilizing interventional ultrasound for precise external intracerebral hemorrhage drain(EICHD) placement in pigs.

关键词： Ultrasound guidance Intracerebral hemorrhage External drain

Physical dispersion state and fluorescent property of Eu-complex in the Eu-complex/silicon rubber composites

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Journal of Rare Earths 2008年第5期26卷 626-632页

作者：温世鹏胡水张小萍张立群刘力 Key Laboratory of Beijing City on Preparation and Processing of Novel Polymer Materials Beijing University of Chemical Technology Key Laboratory for Nanomaterials Ministry of Education Beijing University of Chemical Technology

The fluorescent complex Eu（TTA）2（Phen）（MA）（HTTA=2-Thenoyltrifluoroacetone, Phen=1,10-phenanthroline, MA=Maleic an- hydrider） was synthesized and characterized with elemental analysis, infrared spectrum （IR）, scanning electron microscope （SEM）, X-ray Diffraction（XRD）, differential scanning calorimetry（DSC）, and fluorescent measurement. To explore the effect of different physical dispersion state of Eu-complex on the fluorescent property of the Eu-complex/silicon rubber composites, various quantifies of Eu（TTA）2（phen）（MA） were mixed with silicon rubber （SIR） and peroxide to form uncured composites. These composites were vulcanized to obtain cured Eu-complex/SiR composites at 250 ℃, which was higher than the melting-point of Eu-complex. The SEM, XRD, DSC, and the fluorescent measurement of these composites showed that both the complex molecules dispersed in the silicon rubber during the melting process and the parent Eu-complex particles had positive effects on fluorescent property, whereas the re-crystallized Eu-complex particles and the aggregating complexes formed during the melting-process had negative effects on fluorescent property. For the uncured composites, their fluorescent intensities almost did not change with the increasing amount of Eu-complex. Furthermore, for the composites with small content of Eu-complex, their fluorescent intensities decreased significantly after curing, and this difference in fluorescent intensity became smaller as the content of Eu-complex increases.

关键词： polymer-matrix composites melting blending physical dispersion state fluorescent property rare earths

Predictors and outcomes of photodynamic therapy on circumscribed choroidal hemangiomas in Chinese patients

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Chinese Medical Journal 2014年第15期127卷 2874-2876页

作者： Wang Mingyang Zhang Xinyuan Wang Yanhong Wang Guanglu Beijing Institute of Ophthalmology Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Key Laboratory of Ophthalmology and Visual sciences Beijing 100730China Department of Epidemiology & Biostatistics School of Basic Medicine Peking Union Medical College & Institute of Basic Medical Sciences Chinese Academy of Medical Sciences Beijing 100005 China

Choroidal hemangiomas （CHs） are relatively rare,benign,vascular,hamartomatous *** are categorized to circumscribed choroidal hemangiomas （CCHs） or diffuse choroidal hemangiomas （DCHs） clinically and *** circumscribed CHs （CCHs） are often asymptomatic,they can affect visual acuity （VA） if they are situated beneath the fovea,where they can cause accumulation of secondary subretinal fluid and/or cystic retinal *** to its minimal invasiveness and negligible toxicity to the normal retina,photodynamic therapy （PDT） with verteporfin has been applied widely in the treatment of CCH.1 Treatment strategies for CCHs should take into account tumor size,anatomic location,VA,and presence/absence of *** present study was conducted to identify potential predictors of successful PDT treatment other than those previously *** also present alternative treatment modalities for larger,more complicated ***：circumscribed choroidalhemangiomas; photodynamic therapy; tumor height; predictors and outcomes;success rate;fluorescence angiography; indocyanine green angiography

关键词： circumscribed choroidalhemangiomas photodynamic therapy tumor height predictors and outcomes success rate fluorescence angiography indocyanine green angiography

Cooperative Routing for Maximizing Network Performance of Wireless Networks

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Chinese Journal of Aeronautics 2011年第2期24卷 219-223页

作者： LIU Kai ZHANG Wansheng WANG Li LIU Feng School of Electronics and Information Engineering Beihang University Beijing 100191 China Flight Inspection Center General Administration of Civil Aviation of China Beijing 101312 China

To greatly increase spectral efficiency and improve network performance in wireless networks,a novel cooperative routing algorithm,namely maximum throughput cooperative routing（MTCR） algorithm,is *** to cooperative link model,throughput analysis is presented to evaluate performance improvement in the process of exploiting cooperative commu-nication from physical layer to higher *** the throughput improvement as performance metric,a cooperative relay se-lection scheme is ***,based on the route constructed by adaptive forwarding cluster routing（AFCR） algorithm,each node on the route selects the optimum cooperative node from all the potential cooperative nodes to construct the coopera-tive link with maximum throughput so that cooperative route with maximum network throughput from source to destination can be set *** results show that compared with the noncooperative routing algorithm and minimum power selection de-code-and-forward（MPSDF） routing algorithm,the proposed algorithm can obviously improve network throughput in the pres-ence of low transmission power,large number of nodes and high spectral efficiency.

关键词： cooperative routing cooperative relay throughput cooperative communication wireless networks

Recent advances in small incision lenticule extraction(SMILE)-derived refractive lenticule preservation and clinical reuse

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Engineered Regeneration 2023年第2期4卷 103-121页

作者： Xiaojun Hu Ruoyan Wei Chang Liu Yunzhe Wang Danjuan Yang Ling Sun Fei Xia Shengtao Liu Meiyan Li Xingtao Zhou Eye Institute and Department of Ophthalmology Eye&ENT HospitalFudan UniversityShanghai 200031China Key Laboratory of Myopia NHC Key Laboratory of Myopia(Fudan University)Chinese Academy of Medical SciencesShanghai 200031China Shanghai Research Center of Ophthalmology and Optometry China Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care China

Small incision lenticule extraction(SMILE)has become one of the mainstream refractive surgeries in recent years,with satisfactory efficacy,safety,and ***-derived refractive lenticule,the byproduct of the surgery,holds great potential in clinical practice given its easy access and good *** studies have been published to describe its applications in refractive correction,corneal ectasia diseases,and corneal *** feasibility and safety were validated in both animal models and clinical ***,the preservation method is also crucial for its further promotion and *** techniques are also evaluated and applied in lenticule *** covered the recent advances in the preservation of corneal stromal lenticules and their clinical reuse in this review.

关键词： Small incision lenticule extraction Refractive lenticule Preservation Clinical reuse

一种用于机器人电池电量预测的Sarsa强化学习混合集成方法

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Journal of Central South University 2023年第11期30卷 3867-3880页

作者：彭飞刘辉郑力 Department of Industrial Engineering Tsinghua UniversityBeijing 100084China CRRC Academy Co. Ltd.Beijing 100070China Institute of Artificial Intelligence&Robotics(IAIR) Key Laboratory of Traffic Safety on Track of Ministry of EducationSchool of Traffic and Transportation EngineeringCentral South UniversityChangsha 410075China

建设数据高效互联的轨道交通车间已成为当前轨道交通装备行业转型发展的必然趋势。越来越多样化的移动运输机器人设备成为智能工厂数字化转型过程中的关键。准确预测机器人的电池电量可以指导控制中心提前采取科学合理的指令,确保物流... 详细信息

建设数据高效互联的轨道交通车间已成为当前轨道交通装备行业转型发展的必然趋势。越来越多样化的移动运输机器人设备成为智能工厂数字化转型过程中的关键。准确预测机器人的电池电量可以指导控制中心提前采取科学合理的指令,确保物流运输链高效稳定运行。在本研究中,我们提出了一种基于状态-动作-奖励-状态-动作(Sarsa)强化学习算法的多学习器混合集成方法。首先,采用最大重叠离散小波变换(MODWT)对所测量的机器人原始电源电压数据进行预处理,可以显著降低时间序列数据的非平稳性和波动性。其次,利用门控循环单元(GRU)、深度置信网络(DBN)和长短期记忆(LSTM)对分解后得到的子序列进行预测建模。最后,使用Sarsa强化学习集成策略对上述三个基础预测器进行加权组合。所提出的Sarsa混合集成模型的性能在三个真实移动机器人功率数据集上得到验证。实验结果表明,运输机器人电池动力混合预测模型在鲁棒性、准确性和适应性方面具有竞争力。

关键词：机器人电源管理运输机器人时间序列预测深度学习 Sarsa强化学习集成模型