检索结果-南通市图书馆

Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents

World Journal of Gastroenterology 2013年第46期19卷 8638-8646页

作者： Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E kowalski Myriam Martel Viviane Adam Division of Gastroenterology and Hepatology University of Vermont Division of Gastroenterology McGill University Health Center McGill University Department of Epidemiology and Biostatistics and Occupational Health McGill University Health Center Division of Gastroenterology and Hepatology Dartmouth Hitchcock Medical Center Lebanon Division of Gastroenterology Tufts University School of Medicine Boston Division of Gastroenterology Duke University Medical Center Durham Division of Gastroenterology and Hepatology Thomas Jefferson University Hospital

AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary ***:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French *** patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university *** endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 *** analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive ***:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for *** to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=*** to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of *** an initially planned 120 patients,only 85 patients were ***:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life.

关键词： Randomized Biliary Obstruction Stent Plastic Metal Palliative Common bile duct

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：