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Two-Staged Method for Ice Channel Identification Based on Image Segmentation and Corner Point Regression

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china Ocean Engineering 2024年第2期38卷 313-325页

作者： DONG Wen-bo ZHOU Li DING Shi-feng WANG Ai-ming CAI Jin-yan School of Naval Architecture and Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Naval Architecture Ocean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China

Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of *** the Arctic,merchant ships with low ice class often navigate in channels opened up by *** in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large *** ship may get stuck if steered into ice fields off the *** this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable *** this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point *** first stage employs the image segmentation method to extract channel *** the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression *** training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel *** evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.

关键词： ice channel ship navigation identification image segmentation corner point regression

Dynamic Analysis of A Deepwater Drilling Riser with A New Hang-off System

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china Ocean Engineering 2024年第1期38卷 29-41页

作者： LI Yan-wei LIU Xiu-quan WANG Jin-long CHEN Guo-ming CHANG Yuan-jiang SHENG Lei-xiang Centre for Offshore Engineering and Safety technology China University of PetroleumQingdao 266580China national Engineering Laboratory of Offshore Geophysical and Exploration Equipment China University of PetroleumQingdao 266580China china CNOOC research Institute Co. Ltd.Beijing 100028China

The safety of risers in hang-off states is a vital challenge in offshore oil and gas engineering.A new hang-off system installed on top of risers is proposed for improving the security of *** approach leads to a challenging problem:coupling the dynamics of risers with a new hang-off system combined with multiple structures and complex *** accurately analyze the dynamic responses of the coupled system,a coupled dynamic model is established based on the Euler-Bernoulli beam-column theory and penalty function method.A comprehensive analysis method is proposed for coupled dynamic analysis by combining the finite element method and the Newmarkβ*** analysis program is also developed in MATLAB for dynamic *** simulation results show that the dynamic performances of the risers at the top part are significantly improved by the new hang-off system,especially the novel design,which includes the centralizer and articulation *** bending moment and lateral deformation of the risers at the top part decrease,while the hang-off joint experiences a great bending moment at the bottom of the lateral restraint area which requires particular attention in design and *** platform navigation speed range under the safety limits of risers expands with the new hang-off system in use.

关键词： deepwater drilling riser new hang-off system dynamic analysis finite element method penalty function method

A Distortion Self-Calibration Method for Binocular high Dynamic Light Adjusting and Imaging System Based on Digital Micromirror Device

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IEEE/CAA Journal of Automatica Sinica 2024年第9期11卷 2036-2038页

作者： Pei Wu Yanjie Wang Honghai Sun Zhuoman Wen University of Chinese Academy of Sciences Beijing 100049and NIO Inc.Shanghai 200000China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China

Dear Editor,In order to realize the pixel level light adjusting control of the binocular high dynamic light adjusting and imaging system, this letter proposed a novel self-calibration method. By analyzing the optical design of the system, the causes of the distortion are given and a distortion model is established. Then, a quick and accurate self-calibration method is designed. The experiments indicate that the method can calibrate the two image sensors of the system at the same time,the average pixel deviation of the calibrated system is less than 0.5pixels and the maximum deviation is less than 1 pixel.

关键词： Dynamic system deviation

highly efficient room temperature phosphorescent liquid crystalline polymer optical waveguides for advanced optoelectronics

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Science china Chemistry 2024年第10期67卷 3450-3457页

作者： Jie Li Yan Guan Wei Xia Jin-Kang Chen Jiang Huang Yi Chen Qi Lin Er-Qiang Chen He-Lou Xie Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education and Key Laboratory of Advanced Functional Polymer Materials of CollegesUniversities of Hunan Province and College of ChemistryXiangtan UniversityXiangtan 411105China School of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China Beijing national Laboratory for Molecular Sciences Key Laboratory of Polymer Chemistry and Physics of Ministry of EducationCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

Active organic optical waveguide materials(OOWMs)incorporating room temperature phosphorescence(RTP)hold significant promise for diverse applications in photonic and optoelectronic *** this potential,realizing active RTP optical waveguides with large-sized ordered structures and minimal light loss remains a formidable *** address this issue,we present a groundbreaking thermoplastic active OOWM with low light loss,leveraging room temperature phosphorescent liquid crystalline polymer(LCP).This innovative material can be easily synthesized through the copolymerization of phosphorescent and liquid crystalline *** resulting RTP copolymer exhibits a nematic liquid crystal phase with a phosphorescence lifetime of approximately 0.15 ms and an afterglow duration of around 1 *** the excellent processability of LCP,we successfully produce meter-scale fibers via melt *** RTP LCP fibers,characterized by a high orientation of mesogens along the fiber axis,demonstrate superior light confinement and efficient light conduction compared to unoriented samples,resulting in a low optical loss coefficient of 0.13 dB/***,the thermal responsiveness of the RTP LCP optical waveguide enables its use as a photo *** pioneering work paves the way for the design of new OOWMs tailored for advanced photonics and optoelectronics devices.

关键词： room temperature phosphorescence liquid crystalline polymer active optical waveguide

high-Efficiency Dynamic Scanning Strategy for Powder Bed Fusion by Controlling Temperature Field of the Heat-Affected Zone

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 203-214页

作者： Xiaokang Huang Xiaoyong Tian Qi Zhong Shunwen He Cunbao Huo Yi Cao Zhiqiang Tong Dichen Li State Key Laboratory of Manufacturing Systems Engineering Xi’an Jiaotong UniversityXian 710049China

Improvement of fabrication efficiency and part performance was the main challenge for the large-scale powder bed fusion(PBF)*** this study,a dynamic monitoring and feedback system of powder bed temperature field using an infrared thermal imager has been established and integrated into a four-laser PBF equipment with a working area of 2000 mm×2000 *** heat-affected zone(HAZ)temperature field has been controlled by adjusting the scanning speed ***,the relationship among spot size,HAZ temperature,and part performance has been *** fluctuation of the HAZ temperature in four-laser scanning areas was decreased from 30.85℃to 17.41℃.Thus,the consistency of the sintering performance of the produced large component has been *** on the controllable temperature field,a dynamically adjusting strategy for laser spot size was proposed,by which the fabrication efficiency was improved up to 65.38%.The current research results were of great significance to the further industrial applications of large-scale PBF equipment.

关键词： Powder bed fusion Efficiency Large-scale Spot size Heat-affected zone(HAZ)

Magnetic field imaging with radio-frequency optically pumped magnetometers [Invited]

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Chinese Optics Letters 2024年第6期22卷 38-45页

作者： Xiyu Liu Junlong Han Wei Xiao Teng Wu Xiang Peng Hong Guo School of Electronics Peking UniversityBeijing 100871China

high-sensitivity radio-frequency optically pumped magnetometers (RF-OPMs), working without cryogenic condition, play a critical role in magnetic field imaging(MFI) at low frequencies(e.g., 100 Hz to 1 MHz). We introduce the principle of operation and recent developments of RF-OPMs and focus on reviewing the MFI applications in magnetic induction tomography, ultralow-field magnetic resonance imaging, and magnetic particle imaging. For the applications of RF-OPMs, ranging from industrial monitoring to medical imaging and security screening, the unshielded and portable RF-OPMs(and RF-OPM array)techniques are still under the further development for detecting and scanning over the target object for accomplishing the final three-dimensional imaging, and thus extremely require the abilities of active compensation of the ambient magnetic field and sensor miniaturization in the future.

关键词： magnetic field imaging radio frequency optically pumped magnetometer

Identification of Motor Nuclei in the Medulla Oblongata of Carp for Biological Control

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Journal of Bionic Engineering 2024年第2期21卷 842-851页

作者： Yang Zhao Yong Peng Yudong Wen Lingjun Han Yanhong Yan Xueying Dong Hui Zhang Zheng Zhao Xiaoyue Liu School of Electrical Engineering Yanshan UniversityQinhuangdao066004China School of Mechanical Engineering Yanshan UniversityQinhuangdao066004China Key Laboratory of national Defense of Mechanical Structure and Material Science Under Extreme Conditions Yanshan UniversityQinhuangdao066004China Institute of Marine Science and Engineering Yanshan UniversityQinhuangdao066004China Shijiazhuang University Shijiazhuang050035China

Brain-controlled technology is the key technology in biological control,and the corresponding relationship between animal brain nuclei and motor behavior is the *** purpose of this study was to explore the motor nuclei of the medulla oblongata in *** carps were subjected to electrical stimulation and chemical stimulation experiments,respectively,in the water-free state,and the effective chemical stimulation sites were injected with the pontamine sky blue *** brain tissue sections were obtained by paraffin tissue section technology and the neutral red staining *** comparing the positions of the brain nuclei shown in earlier studies,the motor nerve nuclei in the medulla oblongata were *** brain electrode was implanted into the motor nucleus of the medulla oblongata,and the underwater control experiment and behavioral tests were carried out with different electrical stimulation *** results showed that the abducens nucleus(NVI)was the motor nucleus that controls the ipsilateral steering,and the facial nucleus(NVII)was the motor nucleus that controls the forward *** adjusting the stimulation voltage and the stimulation pulse number,the carp can be stably controlled to achieve a left–right steering motion of 30°–180°and a forward motion of more than 80 cm/*** study indicated that the quantitative control of the steering and forward behavior of the carp can be achieved by electrical stimulation of the NVI and NVII,which provided a certain experimental basis for the accurate control of the carp robot.

关键词： Biological control Carp Medulla oblongata motor nucleus Electrical stimulation technique Chemical stimulation technique

CD87-targeted BiTE and CAR-T cells potently inhibit invasive nonfunctional pituitary adenomas

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Science china(Life Sciences) 2024年第10期67卷 2169-2185页

作者： Yuan Ren Xinjie Bao Ming Feng Bing Xing Wei Lian Yong Yao Renzhi Wang Department of Neurosurgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Recently,bispecific T-cell engagers(BiTEs)and chimeric antigen receptor-modified T cells(CAR-Ts)have been shown to have high therapeutic efficacy in hematological ***87 is highly expressed in solid tumors with an oncogenic *** assess their cytotoxic effects on invasive nonfunctioning pituitary adenomas(iNFPAs),we first examined CD87 expression and its effects on the metabolism of iNFPA *** generated CD87-specific BiTE and CAR/IL-12 T cells,and their cytotoxic effects on iNFPAs cells and in mouse models were ***87 had high expression in i NFPA tissue and cell samples but was undetected in noncancerous brain ***87×CD3 BiTE and CD87 CAR/IL-12 T-cells showed antigenic specificity and exerted satisfactory cytotoxic effects,decreasing tumor cell proliferation in vitro and reducing existing tumors in experimental ***,the above findings suggest that CD87 is a promising target for the immunotherapeutic management of iNFPAs using anti-CD87 BiTE and CD87-specific CAR/IL-12 T cells.

关键词： CD87 chimeric antigen receptor T cells invasive non-functional pituitary adenomas bispecific T cell engager Warburg effect

Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1

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Science china(Life Sciences) 2024年第6期67卷 1212-1225页

作者： Zhijie Hu Mengxia Li Yufeng Chen Liutao Chen Yuting Han Chengyong Chen Xin Lu Nan You Yawen Lou Yingye Huang Zhanfeng Huo Chao Liu Cheng Liang Susu Liu Ke Deng Liangfu Chen Shangwu Chen Guohui Wan Xiaojian Wu Yonggui Fu Anlong Xu State Key Laboratory of Biocontrol Guangdong Province Key Laboratory of Pharmaceutical Functional GenesDepartment of BiochemistrySchool of Life SciencesSun Yat-sen UniversityGuangzhou 510275China Department of General Surgery(Colorectal Surgery)&Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases&Biomedical Innovation Center The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655China national-Local Joint Engineering Laboratory of Druggability and New Drug Evaluation National Engineering Research Center for New Drug and Druggability(cultivation)Guangdong Province Key Laboratory of New Drug Design and EvaluationSchool of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhou 510006China School of Life Sciences Beijing University of Chinese MedicineBeijing 100029China

Generally shortened 3′UTR due to alternative polyadenylation(APA)is widely observed in cancer,but its regulation mechanisms for cancer are not well ***,with profiling of APA in colorectal cancer tissues and poly(A)signal editing,we firstly identified that the shortened 3′UTR of CTNNIBP1 in colorectal cancer promotes cell proliferation and *** found that liquid-liquid phase separation(LLPS)of PABPN1 is reduced albeit with higher expression in cancer,and the reduction of LLPS leads to the shortened 3′UTR of CTNNBIP1and promotes cell proliferation and ***,the splicing factor SNRPD2 upregulated in colorectal cancer,can interact with glutamic-proline(EP)domain of PABPN1,and then disrupt LLPS of PABPN1,which attenuates the repression effect of PABPN1 on the proximal poly(A)*** results firstly reveal a new regulation mechanism of APA by disruption of LLPS of PABPN1,suggesting that regulation of APA by interfering LLPS of 3′end processing factor may have the potential as a new way for the treatment of cancer.

关键词： alternative polyadenylation colorectal cancer CTNNBIP1 PABPN1 liquid-liquid phase separation SNRPD2