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Enzymes inhibitory property,antioxidant activity and phenolics profile of raw and roasted red sorghum grains in vitro

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Food Science and Human Wellness 2019年第2期8卷 142-148页

作者： Emmanuel Anyachukwu Irondi Bosede Mofoluwake Adegoke Emy Sofie Effion Selimat Oluwakemi Oyewo Emmanuel Oladeji Alamu Aline Augusti Boligon Department of Biochemistry Kwara State UniversityMaleteP.M.B.1530IlorinNigeria Department of Applied Sciences Osun State PolytechnicIreeOsun StateNigeria International Institute of Tropical Agriculture(IITA) Grosvenor HouseCroydonCR09 XPUnited Kingdom Phytochemical Research Laboratory Department of Industrial PharmacyFederal University of Santa MariaSanta MariaCEP 97105-900Brazil

Whole grain cereals are important dietary sources for management of metabolic diseases due to the bioactive components they ***,this study investigated enzymes(pancreatic lipase,-amylase,-glucosidase,xanthine oxidase and angiotensin 1-converting enzyme)inhibitory property,antioxidant activity and phenolics profile of raw and roasted red sorghum(Sorghum bicolor)grains in *** of flours of raw and roasted(150◦C and 180◦C,for 20 min)grains were assayed for enzymes inhibitory and antioxidant activities using spectrophotometric methods;while their phenolic constituents were characterized using *** raw grains exhibited strong enzymes inhibitory and antioxidant activities,and contained phenolic acids(gallic,chlorogenic,caffeic,ellagic and p-coumaric acids)and flavonoids(quercetin,luteolin and apigenin).However,whereas the enzymes inhibitory activity and levels of the phenolic compounds in the grains decreased significantly(p<0.05)with increasing roasting temperature,the antioxidant activity ***,roasting at high temperature may not be recommended for the optimum retention of the enzymes inhibitory property and phenolic compounds of red sorghum grains.

关键词： Antioxidant activity Enzymes inhibition Metabolic diseases Phenolic compounds Sorghum grains

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Prevalence of latent eosinophilia among occupational gardeners at Babcock university,Nigeria

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Asian Pacific Journal of Tropical Biomedicine 2016年第6期6卷 511-515页

作者： Ayodele Olushola Ilesanmi Ginnikachi Jennifer Ekwe Rosemary Isioma Ilesanmi Damilola Temitope Ogundele Jacob Kehinde Akintunde Oluwasogo Adewole Olalubi Department of Medical Laboratory Science Babcock University Department of Medical Microbiology Olabisi Onabanjo University Department of Chemical Geological & Physical SciencesChemistry UnitKwara State University Drug Metabolism and Molecular Environmental Toxicology Unit Biochemistry OptionDepartment of Bioscience and BiotechnologyCollege of Pure and Applied SciencesKwara State University School of Allied Health & Environmental Sciences Department of Allied HealthPublic Health UnitKwara State University

Objective: To determine the level of eosinophils present in the blood and sputum samples, presumably as a result of continual occupational exposure to allergens while on duty, as gardeners at Babcock university, ***: Haemocytometer and Olympus microscope were utilized to estimate eosinophils population in 44 blood samples and 21 sputum samples ***: Relationship between the occurrence of eosinophil in blood and the exposure period among Babcock university gardeners had a positive correlation(r = + 0.08,t = 4.55, P < 0.05). It was found that blood eosinophil count in these workers correlated with the length of exposure ***: The nature and the gardening activities are not a risk factor that significantly affect eosinophil level but duration of exposure to allergens. However, all safety precautionary kits and wears should be enforced and embraced by the concerned occupational gardeners so as to avert and subvert its pre-disposing deleterious effect on them.

关键词： Eosinophilia Occupational Exposure Gardeners Duration Allergens

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