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Neural Regeneration Research 2025年第1期20卷 188-190页

作者： Shiho Ito Takeshi Kawauchi Department of Adaptive and Maladaptive Responses in health and Disease Graduate School of MedicineKyoto UniversityKyotoJapan Department of Physiology Keio University School of MedicineTokyoJapan

Cell adhesion plays pivotal roles in the morphogenesis of multicellular *** cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junctions),and macula adhaerens(desmosomes).Although these adhesion complexes are basically observed only in epithelial cells,cadherins,which are the major cell adhesion molecules of adherens junctions,are expressed in both epithelial and non-epithelial tissues,including neural tissues(Kawauchi,2012).The cadherin superfamily consists of more than 100 members,but classic cadherins.

关键词： cerebral skeletal cooperation

Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration

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Neural Regeneration Research 2025年第3期20卷 797-798页

作者： Takayuki Nakagomi Institute for Advanced Medical Sciences Hyogo Medical UniversityNishinomiyaJapan Department of Therapeutic Progress in Brain Diseases Hyogo Medical UniversityNishinomiyaJapan

Brain injuries like ischemic stroke induce endogenous stem cell production. Although the precise traits of stem cells in pathological brains remain unclear, we previously demonstrated that injury/ischemia-induced stem... 详细信息

关键词： ischemia injuries

Monogenic gene therapy for glaucoma and optic nerve injury

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Neural Regeneration Research 2025年第3期20卷 815-816页

作者： Chikako harada Xiaoli Guo Takayuki harada Visual Research Project Tokyo Metropolitan Institute of Medical ScienceTokyoJapan

The prevalence of glaucoma, the second leading cause of global blindness, is increasing due to aging populations. In glaucoma, degeneration of the optic nerve and retinal ganglion cells(RGCs) causes visual field defec... 详细信息

关键词： visual glaucoma degeneration

Asking one mechanism in glial cells during neuroinflammation

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Neural Regeneration Research 2025年第4期20卷 1077-1078页

作者： Xiaoli Guo Chikako harada Takayuki harada Visual Research Project Tokyo Metropolitan Institute of Medical ScienceTokyoJapan

Multiple sclerosis(MS),which is characterized by inflammatory demyelination in the central nervous system(CNS),is the most common neurological disease in the young adult *** autoimmune encephalomyelitis(EAE),an animal model of MS,is often used in preclinical *** data indicate that in addition to immune cells such as T cells and dendritic cells,CNS resident microglia and astrocytes play important roles in demyelinating neuroinflammation(healy et al.,2022).In particular,microglia are key immune-competent cells that can respond to environmental *** depletion of transforming growth factor-β-activated kinase 1,a mitogen-associated protein kinase kinase kinase,in microglia is reported to reduce CNS inflammation and diminish axonal and myelin damage *** suggests that elucidating the mechanisms of microglia-specific responses during pathologies may help in the development of treatments that reduce EAE/MS disease severity(Goldmann et al.,2013).

关键词： inflammation clinical

Upconversion time-stretch infrared spectroscopy

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Light(Science & Applications) 2023年第3期12卷 465-474页

作者： Kazuki hashimoto Takuma Nakamura Takahiro Kageyama Venkata Ramaiah Badarla hiroyuki Shimada Ryoich horisaki Takuro Ideguchi Institute for Photon Science and Technology The University of TokyoTokyo113-0033Japan Department of Physics The University of TokyoTokyo113-0033Japan Graduate School of Information Science and Technology The University of TokyoTokyo113-8656Japan

high-speed measurement confronts the extreme speed limit when the signal becomes comparable to the noise *** the context of broadband mid-infrared spectroscopy,state-of-the-art ultrafast Fourier-transform infrared spectrometers,in particular dual-comb spectrometers,have improved the measurement rate up to a few MSpectra s^(-1),which is limited by the signal-to-noise ***-stretch infrared spectroscopy,an emerging ultrafast frequency-swept mid-infrared spectroscopy technique,has shown a record-high rate of 80 MSpectra s^(-1) with an intrinsically higher signal-to-noise ratio than Fourier-transform spectroscopy by more than the square-root of the number of spectral ***,it can measure no more than~30 spectral elements with a low resolution of several ***,we significantly increase the measurable number of spectral elements to more than 1000 by incorporating a nonlinear upconversion *** one-to-one mapping of a broadband spectrum from the mid-infrared to the near-infrared telecommunication region enables low-loss time-stretching with a single-mode optical fiber and low-noise signal detection with a high-bandwidth *** demonstrate high-resolution mid-infrared spectroscopy of gas-phase methane molecules with a high resolution of 0.017 cm^(-1).This unprecedentedly high-speed vibrational spectroscopy technique would satisfy various unmet needs in experimental molecular science,e.g.,measuring ultrafast dynamics of rreversible phenomena,statistically analyzing a large amount of heterogeneous spectral data,or taking broadband hyperspectral images at a high frame rate.

关键词： spectroscopy noise resolution

Recommender system for discovery of inorganic compounds

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npj Computational Materials 2022年第1期8卷 2084-2090页

作者： hiroyuki hayashi Atsuto Seko Isao Tanaka Department of Materials Science and Engineering Kyoto UniversityKyotoJapan Nano Research Laboratory Japan Fine Ceramics Center(JFCC)NagoyaJapan

A recommender system based on experimental databases is useful for the efficient discovery of inorganic ***,we review studies on the discovery of as-yet-unknown compounds using recommender *** first method used compositional descriptors made up of elemental *** compositions registered in the inorganic crystal structure database(ICSD)were supplied to machine learning for binary *** other method did not use any descriptors,but a tensor decomposition technique was *** predictive performance for currently unknown chemically relevant compositions(CRCs)was determined by examining their presence in other *** to the recommendation,synthesis experiments of two pseudo-ternary compounds with currently unknown structures were ***,a synthesis-condition recommender system was constructed by machine learning of a parallel experimental data-set collected in-house using a polymerized complex *** scores for unexperimented conditions were then *** experiments under the targeted conditions found two yet-unknown pseudo-binary oxides.

关键词： method. inorganic system

Deformable Textile‑Structured Triboelectric Nanogenerator Knitted with Multifunctional Sensing Fibers for Biomechanical Energy harvesting

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Advanced Fiber Materials 2022年第6期4卷 1486-1499页

作者： Li Dong Mingxu Wang Jiajia Wu Chunhong Zhu Jian Shi hideaki Morikawa Graduate School of Medicine Science and TechnologyShinshu University3‑15‑1 TokidaUedaNagano 386‑8567Japan Institute for Fiber Engineering(IFES) Interdisciplinary Cluster for Cutting Edge Research(ICCER)Shinshu University3‑15‑1 TokidaUedaNagano 386‑8567Japan Faculty of Textile Science and Technology Shinshu University3‑15‑1 TokidaUedaNagano 386‑8567Japan Faculty of Systems Science and Technology Akita Prefectural University84‑4 Aza Ebinokuchi TsuchiyaYurihonjoAkita 015‑0055Japan

Fibers and textiles that harvest mechanical energy via the triboelectric effect are promising candidates as power supplies for wearable ***,triboelectric fibers and textiles are often hindered by problems such as complex fabrication processes,limited length,performances below the state-of-the-art of 2D planar configurations,***,we demonstrated a scalable fabrication of core-sheath-structured elastomer triboelectric fibers that combine silicone hollow tubes with ***-electrodes were fabricated via a facile freeze–thawing process of blending polyvinyl alcohol(PVA),gelatin,glycerin,poly(3,4-ethylene dioxythiophene):poly(styrene sulfonate)(PEDOT:PSS),and sodium chloride(NaCl).Such fibers can also be knitted into deformable triboelectric nanogenerator textiles with high electrical outputs up to 106 V and 0.8μA,which could work as reliable power supplies for small ***,we demonstrated fabric materials recognition,Morse code communication,and human-motion-recognition capabilities,making such triboelectric fiber platform an exciting avenue for multifunctional wearable systems and human–machine interaction.

关键词： Triboelectric fiber Deformable triboelectric nanogenerator textile Multifunctional sensing Wearable electronics

Temporal and spatial anti-aliasing for rendering reflections on water waves

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Computational Visual Media 2021年第2期7卷 201-215页

作者： Namo Podee Nelson Max Kei Iwasaki Yoshinori Dobashi hokkaido University Sapporo060-0814Japan University of California Davis95616USA Wakayama University Wakayama640-8441Japan

The reflection of a bright light source on a dynamic surface such as water with waves can be difficult to render well in real time due to reflection aliasing and *** this paper,we propose a solution to this problem by approximating the reflection direction distribution for the water surface as an elliptical Gaussian *** we analytically integrate the reflection contribution throughout the rendering interval *** method can render in real time an animation of the time integrated reflection of a spherical light source on highly dynamic waves with reduced aliasing and flickering.

关键词： real-time rendering anti-aliasing reflection water surface water waves elliptical Gaussian

Solvent-Resistant Wearable Triboelectric Nanogenerator for Energy-harvesting and Self-Powered Sensors

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Energy & Environmental Materials 2024年第5期7卷 376-386页

作者： Yongtao Yu Yuelin Yu hongyi Wu Tianshuo Gao Yi Zhang Jiajia Wu Jiawei Yan Jian Shi hideaki Morikawa Chunhong Zhu Graduate School of Medicine Science and TechnologyShinshu University3-15-1 TokidaUedaNagano 386-8567Japan Institute for Fiber Engineering(IFES) Interdisciplinary Cluster for Cutting Edge Research(ICCER)Shinshu University3-15-1 TokidaUedaNagano 386-8567Japan Faculty of Textile Science and Technology Shinshu University3-15-1 TokidaUedaNagano 386-8567Japan

Wearable triboelectric nanogenerators(TENGs)have attracted attention owing to their ability to harvest energy from the surrounding environment without ***,polyetherimide-Al_(2)O_(3)(PAl)and polyvinylidene fluoride-co-hexafluoropropylene(PVDF-hFP,Ph)nanofiber membranes were used as tribo-positive and tribo-negative materials,*** acid-doped polyaniline(PANI)/cotton fabric(PPCF)and ethylenediamine(EDA)-crosslinked PAl(EPAl)nanofiber membranes were used as triboelectrode and triboencapsulation materials,*** result showed that when the PAl-Ph-based TENG was shaped as a circle with a radius of 1 cm,under the pressure of 50 N,and the frequency of 0.5 hz,the open-circuit voltage(V_(oc))and short-circuit current(I_(sc))reached the highest value of 66.6 V and-93.4 to 110.1 nA,***,the Ph-based TENG could be used as a fabric sensor to detect fabric composition and as a sensor-inductive switch for light bulbs or beeping warning *** the PAl-Ph-based TENG was shaped as a 5×5 cm^(2)rectangle,a 33 pF capacitor could be charged to 15 V in 28 ***,compared to PAl nanofiber membranes,EPAl nanofiber membranes exhibited good dyeing properties and excellent solvent *** PPCF exhibitedhange after washing,bending,and stretching.

关键词： energy-harvesting power supply sensors solvent-resistant wearable triboelectric nanogenerator

Comparison of the effects of submerged laser peening,cavitation peening and shot peening on the improvement of the fatigue strength of magnesium alloy AZ31

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Journal of Magnesium and Alloys 2023年第5期11卷 1592-1607页

作者： hitoshi Soyama Chieko Kuji Yiliang Liao Department of Finemechanics Tohoku University6-6-01 AobaAramakiAoba-kuSendai 980-8579Japan Department of Industrial and Manufacturing Systems Engineering Iowa State University2529 Union Dr.AmesIA 50011United States of America

To investigate the improvement in the fatigue strength of magnesium alloy by peening methods,magnesium alloy AZ31 was treated by submerged laser peening(SLP),cavitation peening(CP),and shot peening(SP),and the fatigue properties were evaluated by a plane bending fatigue *** the case of SLP,both the impact induced by laser ablation(LA)and that caused by laser cavitation(LC),which developed after LA,were *** the present study,the fatigue life at a constant bending stress was examined to determine the suitable *** was found that the fatigue strengths at N=10^(7)for the SLP,CP,and SP specimens treated by each optimum condition were 56%,18%,and 16%higher,respectively,than that of the non-peened(NP)specimen,which was 97 *** key factors in the improvement of fatigue strength by peening methods were work hardening and the introduction of compressive residual stress.

关键词： Magnesium alloy Fatigue strength Laser peening Cavitation peening Shot peening