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Leaf thermal tolerance and sensitivity of temperate tree species are correlated with leaf physiological and functional drought resistance traits

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Journal of Forestry Research 2023年第1期34卷 63-76页

作者： Ines Katharina Münchinger Peter Hajek Berivan Akdogan Astor Torano Caicoya Norbert Kunert Department of Integrative Biology and Biodiversity Research Institute of BotanyUniversity of Natural Resources and Life Sciences ViennaGregor-Mendel Str.331190 ViennaAustria Geobotany University of FreiburgSchanzlestr.179104 FreiburgGermany TUM School of Live SciencesChair of Forest Growth and Yield ScienceTechnical University of MunichGermanyHans-Carl-Von-Carlowitz 285354 FreisingGermany

Climate change is causing more frequent and severe climatic events,such as extreme heat and co-occurring drought,potentially accelerating tree *** tree species will cope better with those extreme events is still being *** study focuses on heat as a physiological stress factor and interspecifi c variation of thermal tolerance and sensitivity traits in 15 temperate coniferous and broad-leaved tree *** investigate(1)whether thermal tolerance and sensitivity traits correlate with a droughtrelated physiological trait,particularly the leaf turgor loss point(πtlp,wilting point),and(2)how thermal tolerance and sensitivity traits co-vary within diff erent tree-functional types classifi ed by morphological and physiological traits of the leaf,i.e.,leaf mass per area(LMA)and percentage loss of area(PLA).The study was carried out in the Traunstein Forest Dynamics Plot of the ForestGEO network in *** temperature response of the maximum quantum yield of photosystem II(F_(v)/F_(m))on leaf discs was determined,from which various physiological leaf traits were estimated,one of which is the breaking point temperature(T_(5)),the temperature at which F_(v)/F_(m)declines by 5%.Additionally,the temperature of 50%(T_(50))and 95%(T_(95))decline in F_(v)/F_(m)was *** decline width between T_(50)and T 5(DW T_(50)−T_(5))was taken as an indicator of the species’thermal *** breaking point temperature ranged from 35.4±3.0 to 47.9±3.9℃among the investigated tree species and T 50 ranged between 46.1±0.4 and 53.6±0.7℃.A large interspecifi c variation of thermal tolerance and sensitivity was *** ash(Fraxinus excelsior L.)was the most heat-sensitive species,while Wild cherry(Prunus avium L.)was the least heat-sensitive *** with a more negativeπtlp tended to have a higher breaking point temperature than species with a less negativeπtlp.A lower thermal sensitivity characterized species with a higher LMA,and high PLA was

关键词： Water stress Heat stress Physiological limitations Climate change ForestGEO

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Targeting the cell cycle in esophageal adenocarcinoma:An adjunct to anticancer treatment

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World Journal of Gastroenterology 2011年第16期17卷 2063-2069页

作者： Martyn dibb Yeng S Ang Department of Gastroenterology Royal Albert Edward Infirmary School of Translational Medicine Faculty of Medical and Human SciencesThe University of Manchester

Esophageal adenocarcinoma is a major cause of cancer death in men in the developed *** poor outcomes with conventional therapies that predominantly target apoptosis pathways have lead to increasing interest in treatments that target the cell cycle.A large international effort has led to the development of a large number of inhibitors,which target cell cycle kinases,including cyclin-dependent kinases,Aurora kinases and polo-like *** phase Ⅰ/Ⅱ trials in solid tumors have often demonstrated only modest clinical benefits of *** may relate in part to a failure to identify the patient populations that will gain the most clinical *** compounds lacking the side effect profile of first-generation compounds may show utility as adjunctive treatments targeted to an individual's predicted response to treatment.

关键词：细胞周期蛋白激酶辅助治疗细胞周期蛋白依赖性激酶腺癌食道抗癌定位 Aurora

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