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Mechanical Properties of Railway High-strength Manufactured Sand Concrete: Typical Lithology, Stone Powder Content and Strength Grade

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Journal of Wuhan University of Technology(Materials science) 2025年第1期40卷 194-203页

作者： WANG Zhen LI Huajian HUANG Fali YANG Zhiqiang WEN Jiaxin SHI Henan Railway Engineering Research Institute China Academy of Railway Science Corporation LimitedBeijing 100081China State Key Laboratory for Track Technology of High-Speed Railway Beijing 100081China

In order to achieve the large-scale application of manufactured sand in railway high-strength concrete structure,a series of high-strength manufactured sand concrete(HMC)are prepared by taking the manufactured sand lithology(tuff,limestone,basalt,granite),stone powder content(0,5%,10%,15%)and concrete strength grade(C60,C80,C100)as *** evolution of mechanical properties of HMC and the correlation between cubic compressive strength and other mechanical properties are *** to river sand,manufactured sand enhances the cubic compressive strength,axial compressive strength and elastic modulus of concrete,while its potential microcracks weaken the flexural strength and splitting tensile strength of *** powder content displays both positive and negative effects on mechanical properties of HMC,and the stone powder content is suggested to be less than 10%.The empirical formulas between cubic compressive strength and other mechanical properties are proposed.

关键词： manufactured sand concrete railway mechanical property lithology stone powder content

Macro-mechanics and Microstructure of Nanomaterial-modified Geopolymer Concrete: A Comprehensive Review

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Journal of Wuhan University of Technology(Materials science) 2025年第1期40卷 204-214页

作者： WANG Tao FAN Xiangqian GAO Changsheng QU Chiyu The National Key Laboratory of Water Disaster Prevention Nanjing Hydraulic Research InstituteNanjing 210024China Southern Marine science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China School of Water Conservancy and Transportation Zhengzhou UniversityZhengzhou 450001China

We have described in detail the effects of nano-SiO_(2),nano-CaCO_(3),carbon nanotubes,and nano-Al_(2)O_(3) on geopolymer concrete from the perspectives of macro mechanics and *** existing research results show that the mechanism of nano-materials on geopolymer concrete mainly includes the filling effect,nucleation effect,and bridging effect,the appropriate amount of nano-materials can be used as fillers to reduce the porosity of geopolymer concrete,and can also react with Ca(OH)2 to produce C-S-H gel,thereby improving the mechanical properties of geopolymer *** optimum content of nano-SiO_(2) is between 1.0%and 2.0%.The optimum content of nano-CaCO_(3) is between 2.0%and 3.0%.The optimum content of carbon nanotubes is between 0.1%and 0.2%.The optimum content of nano-Al_(2)O_(3) is between 1.0%and 2.0%.The main problems existing in the research and application of nanomaterial-modified geopolymer concrete are summarized,which lays a foundation for the further application of nanomaterial in geopolymer concrete.

关键词： nanomaterials low carbon geopolymer concrete macro-mechanics microstructure

A “spore-like” oral nanodrug delivery platform for precision targeted therapy of inflammatory bowel disease

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Chinese Chemical Letters 2025年第03期 417-423页

作者： Junfei Yang Ke Wang Shuxin Sun Tianqi Pei Junxiu Li Xunwei Gong Cuixia Zheng Yun Zhang Qingling Song Lei Wang School of Pharmaceutical sciences Zhengzhou University Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases Henan University Huaihe HospitalTranslational Medicine Center

Colon-targeted oral drug delivery systems are one of the most promising therapeutic strategies for alleviating and curing inflammatory bowel disease(IBD), but they still face challenges in successfully passing through the harsh gastrointestinal environment and intestinal mucus barrier. To overcome the gastrointestinal barriers for oral drug delivery mentioned above, a “spore-like” oral nanodrug delivery platform(Cur/COS/SC NPs) has been developed. Firstly, chitooligosaccharides(COS) are encapsulated on the surface of Curcumin nanoparticles(Cur NPs) to form carrier-free nanoparticles(Cur/COS NPs). Subsequently,inspired by the natural high resistance of spore coat(SC), SC is chosen as the “protective umbrella” to encapsulate Cur/COS NPs for precision targeted therapy of IBD. After oral administration, SC can effectively protect NPs through the rugged gastrointestinal environment and exhibit excellent intestinal mucus penetration characteristics. Moreover, the negatively-charged Cur/COS/SC NPs specifically target positivelycharged inflamed colon via electrostatic interactions. It is demonstrated that Cur/COS/SC NPs can promote the expression of tight junction proteins, inhibit aberrant activation of the Toll-like receptor 4/myeloid differentiation primary response gene 88/nuclear factor-κ B(TLR4/MyD88/NF-κ B) signaling pathway, and downregulate the levels of pro-inflammatory factors, exhibiting excellent anti-inflammatory effects. Notably, it is found that Cur/COS/SC NPs can significantly increase the richness and diversity of gut microbiota, and restore the homeostasis of gut microbiota by inhibiting pathogenic bacteria and promoting probiotics. Hence, Cur/COS/SC NPs provide a safe, efficient, and feasible new strategy for IBD treatment.

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Low-dimensional antimicrobial nanomaterials in anti-infection treatment and wound healing

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Chinese Chemical Letters 2025年第03期 123-131页

作者： Yunfen Gao Liying Wang Chufan Zhou Yi Zhao Hai Huang Jun Wu School of Biomedical Engineering Shenzhen Campus of Sun Yat-sen University Department of Hematology The Seventh Affiliated HospitalSun Yat-sen University School of Life sciences and Bio-pharmaceutics Guangdong Pharmaceutics University Department of Urology Sun Yat-sen Memorial HospitalSun Yat-sen University Bioscience and Biomedical Engineering Thrust The Hong Kong University of Science and Technology (Guangzhou) Division of Life science The Hong Kong University of Science and Technology

Bacterial infections have always been a major threat to human health. Skin wounds are frequently exposed to the external environment, and they may become contaminated by bacteria derived from the surrounding skin, the local environment, and the patient's own endogenous sources. Contaminated wounds may enter a state of chronic inflammation that impedes healing. Urgent development of antibacterial wound dressings capable of effectively combating bacteria and overcoming resistance is necessary. Nanotechnology and nanomaterials present promising potential as innovative strategies for antimicrobial wound dressings, owing to their robust antibacterial characteristics and the inherent advantage of avoiding antibiotic resistance. Therefore, this review provides a concise overview of the antimicrobial mechanisms exhibited by low-dimensional nanomaterials. It further categorizes common low-dimensional antimicrobial nanomaterials into zero-dimensional(0D), one-dimensional(1D) and two-dimensional(2D)nanomaterials based on their structural characteristics, and gives a detailed compendium of the latest research advances and applications of different low-dimensional antimicrobial nanomaterials in wound healing, which could be helpful for the development of more effective wound dressings.

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Lactobacillus acidophilus FCQHC4L1 strengthens the intestinal mucus barrier and inhibits endoplasmic reticulum stress

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Food science and Human Wellness 2025年第1期14卷 78-90页

作者： Yuli Qi Leilei Yu Fengwei Tian Wei Chen Xiaoming Liu Qixiao Zhai State Key Laboratory of Food science and Technology Jiangnan UniversityWuxi 214122China School of Food science and Technology Jiangnan UniversityWuxi 214122China National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China

Mucin 2(MUC2)is a critical component of the intestinal mucus *** acid bacteria(LAB)strains can improve mucosal *** this study,we determined the expression of Muc2 induced by dead bacteria and cell-free conditioned medium(CM)of 50 LAB strains in the human goblet cell line,*** bacteria or CM of LAB affected the Muc2 expression in a species-and strain-specific manner under ***,LAB strains with different regulatory abilities were selected,gavaged into mice,and exposed to dextran sodium sulfate(DSS)after 1 *** LAB strains inhibited intestinal injury to different degrees,with Lactobacillus acidophilus FCQHC4L1 exerting the most potent ***4L1 significantly decreased the secretion of pro-inflammatory factors,promoted the expression and secretion of mucin,and inhibited colitis *** strain also regulated the gut microbiota and increased the secretion of butyric ***,CM of FCQHC4L1 inhibited endoplasmic reticulum(ER)stress and ameliorated the abnormal expression of MUC2 by suppressing the activation of the GRP78/ATF6 and GRP78/IRE1/XBP1 signaling *** results highlight the potential of FCQHC4L1 as a therapeutic agent for strengthening the mucus barrier and improving the gut health.

关键词： Mucin Probiotic Lactobacillus acidophilus Gut microbiota Endoplasmic reticulum(ER)stress

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Testing the quantum effects near the event horizon with respect to the black hole shadow

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Chinese Physics C 2022年第8期46卷 220-229页

作者： Zhaoyi Xu Meirong Tang College of Physics Guizhou UniversityGuiyang 550025China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China

In recent years,the study of quantum effects near the event horizon of a black hole(BH)has attracted extensive *** has become one of the important methods to explore BH quantum properties using the related properties of a quantum deformed *** this work,we study the effect of a quantum deformed BH on the BH shadow in two-dimensional Dilaton *** this model,quantum effects are reflected by the quantum correction parameter *** calculation,we find that:(1)the shape of the shadow boundary of a rotating BH is determined by the BH spin a,the quantum correction parameter m,and the BH type parameter n;(2)when the spin a=0,the shape of the BH shadow is a perfect circle;when a≠0,the shape is distorted;if the quantum correction parameter m=0,their shapes reduce to the cases of a Schwarzschild BH and Kerr BH,respectively;(3)the degree of distortion of the BH shadow is different for various quantum correction parameters m;with an increase in the parameter m,the boundary of the BH shadow expands;(4)the size of the BH shadow varies greatly with respect to various quantum deformed BHs(n),and the change in BH shadow shape caused by parameter n is similar to that caused by parameter m,which indicates that there is a"degenerate phenomenon"between the two *** the value of m in actual physics should be very small,the current observations of the event horizon telescope(EHT)cannot distinguish quantum effects from the BH *** future BH shadow measurements,it will be possible to distinguish quantum deformed BHs,which will help to better understand the quantum effects of BHs.

关键词： BH shadow quantum deformed BHs quantum effect event horizon telescope

Multiple Tin Compounds Modified Carbon Fibers to Construct Heterogeneous Interfaces for Corrosion Prevention and Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第1期17卷 507-527页

作者： Zhiqiang Guo Di Lan Zirui Jia Zhenguo Gao Xuetao Shi Mukun He Hua Guo Guanglei Wu Pengfei Yin College of science Sichuan Agricultural UniversityYa’an 625014People’s Republic of China School of Materials science and Engineering Hubei University of Automotive TechnologyShiyan 442002People’s Republic of China Institute of Materials for Energy and Environment State Key Laboratory of Bio‑Fibers and Eco‑TextilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071People’s Republic of China Shaanxi Key Laboratory of Macromolecular science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China

Currently,the demand for electromagnetic wave(EMW)absorbing materials with specific functions and capable of withstanding harsh environments is becoming increasingly ***-component interface engineering is considered an effective means to achieve high-efficiency EMW ***,interface modulation engineering has not been fully discussed and has great potential in the field of EMW *** this study,multi-component tin compound fiber composites based on carbon fiber(CF)substrate were prepared by electrospinning,hydrothermal synthesis,and high-temperature thermal *** utilizing the different properties of different substances,rich heterogeneous interfaces are *** effectively promotes charge transfer and enhances interfacial polarization and conduction *** prepared SnS/SnS_(2)/SnO_(2)/CF composites with abundant heterogeneous interfaces have and exhibit excellent EMW absorption properties at a loading of 50 wt%in epoxy *** minimum reflection loss(RL)is−46.74 dB and the maximum effective absorption bandwidth is 5.28 ***,SnS/SnS_(2)/SnO_(2)/CF epoxy composite coatings exhibited long-term corrosion resistance on Q235 steel ***,this study provides an effective strategy for the design of high-efficiency EMW absorbing materials in complex and harsh environments.

关键词： Electrostatic spinning Component regulation Heterogeneous interfaces Electromagnetic wave absorption Corrosion protection

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

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Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-Qing Chen Yong-Qi Li Yu-Long Wang Mei-Chen Liu Yun-Bo Ruan Yang Zhang Shu-Juan Liu Qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

Molecular Mechanism Behind the Capture of Fluorinated Gases by Metal–Organic Frameworks

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Nano-Micro Letters 2025年第5期17卷 407-462页

作者： Qian Wang Yong Hu Yifan Gu College of Environmental science and Engineering State Key Laboratory of Pollution Control and Resource ReuseTongji UniversitySiping Rd 1239Shanghai 200092People’s Republic of China Department of Polymeric Materials School of Materials Science and EngineeringTongji UniversityCaoan Road 4800Shanghai 201804People’s Republic of China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092People’s Republic of China Key Laboratory of Cities’Mitigation and Adaptation to Climate Change China Meteorological Administration(CMA)Tongji UniversityShanghai 200092People’s Republic of China

Fluorinated gases(F-gases)play a vital role in the chemical industry and in the fields of air conditioning,refrigeration,health care,and organic ***,the direct emission of waste gases containing F-gases into the atmosphere contributes to greenhouse effects and generates toxic *** porous materials for the energy-efficient capture,separation,and recovery of F-gases is highly ***,as a highly designable porous adsorbents,metal–organic frameworks(MOFs)exhibit excellent selective sorption performance toward F-gases,especially for the recognition and separation of different F-gases with highly similar properties,showing their great potential in F-gases control and *** this review,we discuss the capture and separation of F-gases and their azeotropic,near-azeotropic,and isomeric mixtures in various application scenarios by MOFs,specifically classify and analyze molecular interaction between F-gases and MOFs,and interpret the mechanisms underlying their high performance regarding both adsorption capacity and selectivity,providing a repertoire for future materials *** faced in the transformation research roadmap of MOFs adsorbent separation technologies toward F-gases are also discussed,and areas for future research endeavors are highlighted.

关键词： Fluorinated gas Metal–organic framework Adsorption Separation Molecular interaction