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Decentralized damage diagnostic technique for tall buildings using VARMAX model

Earthquake Engineering and Engineering Vibration 2022年第2期21卷 417-439页

作者： K.Lakshmi J.Prawin CSIR-Structural Engineering Research Centre CSIR RoadChennai 600113Tamil NaduIndia

Civil infrastructure,especially buildings,are becoming more slender,tall,and multipurpose,creating a need to continuously monitor their health to ensure the safety and security of human lives and assets.While the majority of structural health monitoring techniques use measurements from the entire structure,in this study,an output-only damage diagnostic technique using a decentralized concept(subdomain-based)for tall buildings and employing a vector form of the autoregressive moving average with exogenous input(VARMAX)model is proposed,which offers reduced instrumentation and data handling requirements.Unlike other decentralized approaches,this technique predicts more than one DOF at a time so the number of subdomains required for the diagnosis of the complete structure is minimized.The proposed subdomain-based damage diagnostic algorithm works with ambient loads and does not require any correlated numerical models since it is solely based on measured data.The proposed algorithm can identify the time instant of damage,spatial location(s)and characterize the damage intensity.Efforts have been made to account for confounding factors such as environmental and operational variabilities separate from measurement noise to avoid false positive alarms.The effectiveness of the proposed technique is illustrated using synthetic time history responses from a twenty-story framed structure under ambient loading and an experimental study on a ten-story framed structure.Both numerical and experimental investigations confirm the effectiveness of the method and its robustness to environmental/operational variabilities and measurement noise.

关键词： structural health monitoring subdomain high-rise buildings shear-type buildings VARMAX model environmental and operational variability measurement noise

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Phytochemical analysis and anticancer capacity of Shemamruthaa,a herbal formulation against DMBA-induced mammary carcinoma in rats

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Asian Pacific Journal of Tropical Medicine 2013年第12期6卷 925-933页

作者： Ayyakkannu Purushothaman Elumalai Nandhakumar Panchanatham Sachdanandam Department of Medical Biochemistry.Dr.ALM Post-Graduate Institute of Basic Medical Sciences University of MadrasTaramani CampusChennai-600113 .India

Objective:To investigate the bioactive-constituents of Shemamruthaa(SM),a herbal combination and its therapeutic effects on the mitochondrial functions with reference to lipid peroxidation(LPO),antioxidant status,citric acid cycle enzymes and electron transport chain enzymes in mammary tissues of 7,12-dimethylbenz(a)-anthracene(DMBA)induced mammary carcinoma in rat model.Methods:Adult Female Sprague-Dawley rats were used for the study and were divided into four groups.CroupⅠserved as control and CroupⅡrats were induced mammary carcinoma by administration of DMBA(25 mg/kg b.w.)orally.The normal and cancer-induced rats(GroupⅢ)were treated with SM(400 mg/kg b.w./day)orally by gastric incubation for 14days.CroupⅣrats served as SM-treated control animals.Results:Cancer-induced rats showed a considerably increased level of LPO with concomitant decreased levels of antioxidants,citric acid cycle enzymes,electron transport chain enzymes and cytochrome contents in the mammary tissue.Treatment with SM brought back the aforementioned biochemical parameters to near normal.Conclusions:From the results,it can be inferred that Shemamruthaa possesses significant anticancer effect through its role in attenuation of LPO,prevention of membrane damage and restoring membrane integrity.

关键词： Phyllanthus emblica Hibiscus rosa-sinensis Mammary carcinoma Trilinolein Flavonoids Mitochondrial oxidative stress

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Anti-diabetic effect of methanolic leaf extract of Pongamia pinnata on streptozotocin induced diabetic rats

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Journal of Coastal Life Medicine 2013年第2期 113-117页

作者： Selvaraju Kavipriya Narayanaswamy Tamilselvan Thirunavukkarasu Thirumalai Gangaipillai Arumugam Department of Biochemistry Adhiparasakthi college of Arts and ScienceKalavaiTamilnaduIndia Division of Biomolecules and Genetic Division VIT UniversityVelloreTamilnaduIndia P.G and Research Department of ZoologyVoorhees CollegeVellore-632001TamilnaduIndia

Objective:To study the anti-diabetic effect of methanolic leaf extract of Pongamia pinnata(P.pinnata)on streptozotocin induced diabetic rats.Methods:Anti-diabetic activity of P.pinnata leaf extract at dosage of 500 mg/kg and 1 g/kg body weight was evaluated.Results:The levels of glucose,triglycerides,total cholesterol and serum glutamic pyruvic transaminase were significantly increased in streptozotocin induced diabetic rats when compared to that of the normal rats.After supplemented with plant extract,significant lower blood glucose level was recorded.Conclusions:The methanolic leaf extract of P.pinnata has been potent anti-diabetic effect in male albino rats.

关键词： Pongamia pinnata Diabetes mellitus Medicinal plant Cholesterol

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