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基于最小生成树NSGA-2算法的改进

计算机工程与应用 2007年第24期43卷 32-36,68页

作者：李密青郑金华湘潭大学信息工程学院湖南湘潭411105

多目标进化算法(MOEA)的一个关键就是保持解的分布度,提出了一种用最小生成树的边的权值来表示个体聚集距离的方法,并且对NSGA-2的交叉算子和变异率进行了改进。实验结果表明,与NSGA-2相比该方法(MST-NSGA-2)在解的分布度上有较大的提高... 详细信息

多目标进化算法(MOEA)的一个关键就是保持解的分布度,提出了一种用最小生成树的边的权值来表示个体聚集距离的方法,并且对NSGA-2的交叉算子和变异率进行了改进。实验结果表明,与NSGA-2相比该方法(MST-NSGA-2)在解的分布度上有较大的提高,并且有着良好的收敛性。

关键词：多目标进化算法聚集距离最小生成树非均匀算术交叉

Evaluation on Fishery Resources in Daxingshan Artificial Reef Area of Huidong County

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Asian Agricultural Research 2013年第12期5卷 80-85页

作者： Xue FENG Pimao CHEN Huiquan LI Jiezhang HONG South China Sea Fisheries Research Institute Chinese Academy of Fishery Sciences/Scientific Observing and Experimental Station of South China Sea Fishery Resources & EnvironmentsMinistry of Agriculture College of Marine Sciences Shanghai Ocean University Guangdong Provincial Oceanic and Fishery Environment Monitoring Center

In order to evaluate placement of artificial reefs in Huidong County and observe biological aggregating effect of fishery resources,background investigation and follow-up investigation were carried out for trawl fishing and gill-net fishing in Daxingshan artificial reef *** biological resource density index(D),Margalef species richness index(R),Shannon-Winener diversity index(H'),and Pileou evenness index(J')were used to study diversity of water biological population and resource *** fishing investigation indicated that after placement of reefs,there was significant increase in quantity of species of nekton,total resource density,species richness index,and diversity index in reef area,which were 1.321,2.07,1.012 and 1.084 times the value before placement of reefs ***-net fishing investigation indicated that after placement of reefs,the quantity of species of nekton,total resource density,species richness index,and diversity index in reef area were 2.571,7.976,2.399 and 2.667 times the value before placement of reefs *** reef placement,fishes and crabs become dominant *** showed that after reef placement,attraction effect of fishes is significant,community structure is obviously optimized,and water environment in reef area is significantly ***,it proved that the multiplication system through artificial reefs has been basically established in Daxingshan reef area of Huidong County.

关键词： Artificial reef Fish-aggregating effect Resource m

氟代柠檬酸对体外培养的神经胶质瘤细胞G422增殖的抑制效应

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Zoological Research 2008年第4期29卷 427-430页

作者：瞿家桂王正波董锦润马原野中国科学技术大学生命科学学院中国科学院昆明动物研究所灵长类认知实验室中国科学院昆明灵长类研究中心云南昆明650223 昆明Biomed International 云南昆明650223

为研究氟代柠檬酸(Fluorocitrate)对体外培养的神经胶质瘤细胞生长的影响,采用MTT法研究不同的氟代柠檬酸浓度(0.0025mmol/L,0.005mmol/L,0.01mmol/L,0.025mmol/L和0.1mmol/L)和作用时间(36h,48h和60h)对神经胶质瘤细胞G422增殖的影响。结果发现:(1)氟代柠檬酸可抑制G422细胞的增殖,并且其抑制作用随氟代柠檬酸浓度的增加而增强;(2)高浓度(0.01mmol/L,0.025mmol/L和0.1mmol/L)氟代柠檬酸对G422细胞的增殖抑制作用随作用时间的延长而增强;(3)低浓度(0.0025mmol/L和0.005mmol/L)氟代柠檬酸对G422细胞的增殖抑制作用不随作用时间的延长而改变。实验表明,氟代柠檬酸能够抑制神经胶质瘤细胞的增殖,其抑制能力随氟代柠檬酸浓度的增加和作用时间的延长而加强。

关键词：氟代柠檬酸神经胶质瘤细胞 MTT 增殖抑制效应

Metamaterial Absorbers in Terahertz Band

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Journal of Electronic Science and Technology 2013年第4期11卷 360-366页

作者： Qi-Ye Wen Huai-Wu Zhang Qing-Hui Yang Man-Man Mo the State Key Laboratory of Electronic Films and Integrated Devices University of Electronic Science and Technology of China

In recent years, a great deal of effort has been made to a create terahertz （THz） wave absorber based on metamaterials （MM）. Metamaterials absorbers have a variety of potential applications including thermal emitters, detector, stealth technology, phase imaging, etc. In this paper, we firstly introduce the basic structure and work principle of the THz MM absorbers, and a transmission line model is developed for devices analysis. To expand the application of THz absorbers, dual-band and broadband THz MM absorbers are designed, fabricated, and measured. At the end of this article, the future development trends of MM absorbers are discussed.

关键词： Absorbers broadband dual-band,metamaterials terahertz transmission line mode.

Delta EEG Activity in Left Orbitofrontal Cortex in Rats Related to Food Reward and Craving

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Zoological Research 2008年第3期29卷 260-264页

作者：付玉陈艳梅曾涛彭沿平田绍华马原野中国科学院昆明动物研究所灵长类认知实验室

The orbitofrontal cortex （OFC） is particularly important for the neural representation of reward value. Previous studies indicated that electroencephalogram （EEG） activity in the OFC was involved in drug administration and withdrawal. The present study investigated EEG activity in the OFC in rats during the development of food reward and craving. Two environments were used separately for control and food-related EEG recordings. In the food-related environment rats were first trained to eat chocolate peanuts; then they either had no access to this food, but could see and smell it （craving trials）, or had free access to this food （reward trials）. The EEG in the left OFC was recorded during these trials. We showed that, in the food-related environment the EEG activity peaking in the delta band （2-4 Hz） was significantly correlated with the stimulus, increasing during food reward and decreasing during food craving when compared with that in the control environment. Our data suggests that EEG activity in the OFC can be altered by food reward; moreover, delta rhythm in this region could be used as an index monitoring changed signal underlying this reward.

关键词： Orbitofrontal cortex EEG Reward Craving Delta band

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中药及复方的药动药效整合分析

中药及复方的药动药效整合分析

A Composite Service Provision Method Based on Novel Node Model in Mobile Ad Hoc Networks

药物临床评价与定量药理学国家级继续教育学习班

作者：谢海棠 Anhui Provincial Center for Drug Clinical Evaluation Chinese Journal of Clinical Pharmacology and Therapeutics

Overview概述TCM的概念Traditional Chinese medicine(TCM)-Ancient style of medicine based on ancient Chinese philosophical ideas which includes Traditional Chinese herbs. acupuncture,moxibustion,Tui-na therap and Qigong therapy中国传统医学(中医)风格的古代医学的基础上古老的中国哲学思想,其中包括中国传统的中草药、针灸、艾灸、推拿疗法和气功疗法。

关键词：

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China Communications 2014年第4期11卷 130-142页

作者： WU Xiaokun TIAN Yue WU Jiyan CHENG Bo CHEN Junlian State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications Beijing 100876 E R. China

Composite service provision in mobile ad hoc networks encounters great challenges and its success rate is not satisfactory because the nodes' locations are dynamic and the nodes maybe unavailable at any *** service is built through the service *** mobile ad hoc networks,the factors influencing the success rate of service composition are mainly the number of nodes and the time spent for the *** node's failure probability is proportional to the length of time the node exist in the *** order to improve the success rate of service composition,we take several ***,we split the service requirement into several segments and cluster the nodes,so that the nodes' waiting time for service composition can be ***,we propose a new node model of "one node contains multiple services" in mobile ad hoc *** this type of nodes model,the number of nodes required for service composition can be *** means can increase the success rate of service composition.

关键词： service provision service composition mobile ad hoe networks cluster requirement splitting

Influence of perfusate on liver viability during hypothermic machine perfusion

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World Journal of Gastroenterology 2015年第29期21卷 8848-8857页

作者： Jun-Jun Jia Jing Zhang Jian-Hui Li Xu-Dong Chen Li Jiang Yan-Fei Zhou Ning He Hai-Yang Xie Lin Zhou Shu-Sen Zheng Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital College of Medicine Zhejiang University Key Laboratory of Combined Multiorgan Transplantation Ministry of Public Health Zhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery First Affiliated Hospital Zhejiang University School of Medicine Department of Vascular Surgery First Affiliated Hospital Zhejiang University School of Medicine

AIM: To optimize the perfusates used for hypothermicmachine perfusion(HMP).METHODS: Sprague-Dawley rats were assigned randomly to three groups(n = 12 per group) that received either saline, University of Wisconsin coldstorage solution(UW) or histidine-tryptophan-ketoglutarate solution(HTK) as the perfusate. Each group was divided into two subgroups: static cold storage(SCS) and HMP(n = 6 per subgroup). The liver graft was retrieved according to the method described by Kamada. For the SCS group, the graft was directly placed into cold perfusate(0-4?℃) for 6 h after liver isolation while the portal vein of the graft was connected to the perfusion machine for the HMP group. Then the perfusates were collected at different time points for analysis of aspartate aminotransferase(AST), alanine transaminase(ALT) and lactate dehydrogenase(LDH) levels. Liver tissues were obtained for evaluation of histology, dry/wet weight(D/W) ratio, and malondialdehyde(MDA) and adenosine-triphosphate(ATP) levels. The portal vein pressure and velocity were monitored in real time in all HMP ***: Comparison of HMP and SCS: Regardless of the perfusate, HMP improved the architecture of donor graft in reducing the congestion around sinusoids and central vein and maintaining sinusoid lining in morphology; HMP improved liver function in terms of ALT, AST and LDH, especially during the 3-6 h period(SCS vs HMP using saline: ALT3, 225.00 ± 105.62 vs 49.50 ± 18.50, P = 0.047; LDH3, 1362.17 ± 563.30 vs 325.75 ± 147.43, P = 0.041; UW: LDH6, 2880.14 ± 948.46 vs 2135.00 ± 174.27, P = 0.049; HTK, AST6, 307.50 ± 52.95 vs 185.20 ± 20.46, P = 0.041); HMP decreased MDA level(saline, 2.79 ± 0.30 vs 1.09 ± 0.09, P = 0.008; UW, 3.01 ± 0.77 vs 1.23 ± 0.68, P = 0.005; HTK, 3.30 ± 0.52 vs 1.56 ± 0.22, P = 0.006). Comparison among HMP subgroups: HTK showed less portal vein resistance than UW and saline(vs saline, 3.41 ± 0.49 vs 5.00 ± 0.38, P < 0.001; vs UW, 3.41 ± 0.49 vs 4.52 ± 0.63, P = 0.007); UW redu

关键词： Hypothermic machine perfusion Staticcold storage Liver viability Wisconsin cold-storagesolution Histidine-tryptophan-ketoglutarate solution

Mesenchymal stem cells: Molecular characteristics and clinical applications

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World Journal of Stem Cells 2010年第4期2卷 67-80页

作者： Farbod Rastegar Deana Shenaq Eric R Wagner Stephanie H Kim Russell R Reid Hue H Luu Rex C Haydon Molecular Oncology Laboratory Department of Surgery The University of Chicago Medical Center Key Laboratory of Diagnostic Medicine Designated by Chinese Ministry of Education and the Affiliated Hospitals of Chongqing Medical University Chongqing 400016 China

Mesenchymal stem cells (MSCs) are non-hematopoietic stem cells with the capacity to differentiate into tissues of both mesenchymal and non-mesenchymal origin. MSCs can differentiate into osteoblastic, chondrogenic, and adipogenic lineages, although recent studies have demonstrated that MSCs are also able to differentiate into other lineages, including neuronal and cardiomyogenic lineages. Since their original isolation from the bone marrow, MSCs have been successfully harvested from many other tissues. Their ease of isolation and ex vivo expansion combined with their immunoprivileged nature has made these cells popular candidates for stem cell therapies. These cells have the potential to alter disease pathophysiology through many modalities including cytokine secretion, capacity to differentiate along various lineages, immune modulation and direct cell-cell interaction with diseased tissue. Here we first review basic features of MSC biology including MSC characteristics in culture, homing mechanisms, differentiation capabilities and immune modulation. We then highlight some in vivo and clinical evidence supporting the therapeutic roles of MSCs and their uses in orthopedic, autoimmune, and ischemic disorders.

关键词： Mesenchymal stem cells Bone marrow stem cell Mesenchymal stromal cell Autoimmune disease Cell-based therapy Autologous transplant Therapeutic application