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Effect of modified biopsy forceps on the diagnosis of malignant biliary strictures:A randomized controlled trial

Chinese Medical Journal 2024年第18期137卷 2248-2250页

作者： Guochen Shang Yu Jin Zhen Ding Rong Lin Department of Gastroenterology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Endoscopy Center The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510010China

To the Editor:Malignant biliary strictures are typically associated with highly aggressive and diagnostically challenging diseases,including cholangiocarcinoma,pancreatic cancer,gallbladder cancer,liver cancer,and metastatic cancer.[1]Biliary biopsy during endoscopic retrograde cholangiopancreatography(ERCP)is the primary method for diagnosing biliary *** a biopsy through forceps sampling is a technically intricate procedure that involves maneuvering the biopsy forceps through the duodenal papilla to access the biliary ***.

关键词： biopsy biliary stricture

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A novel intelligent chromo capsule endoscope for the diagnosis of neoplastic lesions in the gastrointestinal tract

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Gastroenterology Report 2023年第1期11卷 291-299页

作者： Huiying Shi Suya Pang Fanhua Ming Tianyi Yangdai Shuxin Tian Rong Lin Department of Gastroenterology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiP.R.China Ankon Technologies Co. LtdWuhanHubeiP.R.China Department of Gastroenterology The First Affiliated Hospital of Medical CollegeShihezi UniversityShiheziXinjiangP.R.China

Background:Chromoendoscopy has not been fully integrated into capsule *** study aimded to develop and validate a novel intelligent chromo capsule endoscope(ICCE).Methods:The ICCE has two modes:a white-light imaging(WLI)mode and an intelligent chromo imaging(ICI)*** performance of the ICCE in observing colors,animal tissues,and early gastrointestinal(GI)neoplastic lesions in humans was *** captured by the ICCE were analysed using variance of Laplacian(VoL)values or image contrast ***:For color observation,conventional narrow-band imaging endoscopes and the ICI mode of the ICCE have similar spectral *** with the WLI mode,the ICI mode had significantly higher VoL values for animal tissues(2.15461.044 vs 3.80061.491,P=0.003),gastric precancerous lesions and early gastric cancers(2.24260.162 vs 6.64260.919,P<0.001),and colon tumors(3.89661.430 vs 11.88267.663,P<0.001),and significantly higher contrast for differentiating tumor and non-tumor areas(0.06960.046 vs 0.14460.076,P=0.005).More importantly,the sensitivity,specificity,and accuracy of the ICI mode for early GI tumors were 95.83%,91.67%,and 94.64%,respectively,which were significantly higher than the values of the WLI mode(78.33%[P<0.001],77.08%[P=0.01],and 77.98%[P<0.001],respectively).Conclusions:We successfully integrated ICI into the capsule *** ICCE is an innovative and useful tool for differential diagnosis based on contrast-enhanced images and thus has great potential as a superior diagnostic tool for early GI tumor detection.

关键词： capsule endoscopy chromoendoscopy intelligent chromo capsule endoscope white-light imaging intelligent chromo imaging

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