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External mass transfer from/to a single sphere in a nonlinear uniaxial extensional creeping flow

Chinese Journal of Chemical Engineering 2022年第1期35卷 230-245页

作者： Anjun Liu Jie Chen Moshe Favelukis Meng Guo Meihong Yang Chao Yang Tao Zhang Min Wang Hao-yue Quan Qilu University of Technology(Shandong Academy of Sciences) Shandong Computer Science Center(National Supercomputer Center in Jinan)Jinan 250101China CAS Key Laboratory of Green Process and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China Department of Chemical Engineering Shenkar College of Engineering and DesignRamat-Gan5252626Israel Dynamic Machinery Institute of Inner Mongolia Inner MongoliaHohhot 010010China

This work systematically simulates the external mass transfer from/to a spherical drop and solid particle suspended in a nonlinear uniaxial extensional creeping *** mass transfer problem is governed by three dimensionless parameters:the viscosity ratio(λ),the Peclet number(Pe),and the nonlinear intensity of the flow(E).The existing mass transfer theory,valid for very large Peclet numbers only,is expanded,by numerical simulations,to include a much larger range of Peclet numbers(1≤Pe≤105).The simulation results show that the dimensionless mass transfer rate,expressed as the Sherwood number(5 h),agrees well with the theoretical results at the convection-dominated regime(Pe>103).Only when E>5/4,the simulated Sh for a solid sphere in the nonlinear uniaxial extensional flow is larger than theoretical results because the theory neglects the effect of the vortex formed outside the particle on the rate of mass *** correlations are proposed to predict the influence of the dimensionless governing parameters(λ,Pe,E)on the Sherwood number(Sh).The maximum deviations of all empirical correlations are less than 15%when compared to the numerical simulated results.

关键词： External mass transfer Nonlinear extensional flow Sphere Empirical correlation

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Effects of annealing temperature on microstructure and properties of tailor-rolled blank of medium-manganese steel

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Journal of Iron and Steel Research(International) 2020年第8期27卷 933-939页

作者： Ying Zhi Di-wen Ke Xiang-hua Liu Zhi-xin Feng State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina School of Materials Science and Engineering Northeastern UniversityShenyang 110819LiaoningChina

The microstructure and mechanical properties of tailor-rolled blank (TRB) of medium-manganese steel during annealing were investigated. The annealing process of austenite-reverted transformation of the experimental steel was formulated. The effects of different morphologies on properties with different annealing temperatures in different thickness zones of TRB were analyzed. In the thin zone, the morphology is blocky, and in the thick zone, the morphology is lamellar. At the same annealing temperature, the tensile strength of the thick zone is lower than that of the thin zone, and the elongation and product of strength and elongation (PSE) of the thick zone are higher than those of the thin zone. With the increase in annealing temperature, the tensile strength increases, while the yield strength, the elongation and the PSE all decrease in the same thickness zone. Because the stability of lamellar austenite is higher than that of blocky austenite, the comprehensive mechanical properties in the thick zone are good. At the annealing temperature of 640 ℃, the experimental steel has the best comprehensive mechanical properties, and the maximum PSE is more than 40.0 GPa% in different thickness zones. Particularly, PSE is up to 45.6 GPa% in the thickness zone of 2.0 mm.

关键词： Tailor-rolled blank Medium-manganese steel Annealing temperature Austenite-reverted transformation Product of strength and elongation

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Mechanism of Yiyi Fuzi Baijiang powder in treatment of ulcerative colitis on network pharmacology and m olecular docking

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TMR Pharmacology Research 2022年第2期2卷 20-27页

作者： Jing-Kang Mu Wen-Ya Feng Tao Yu First College of Clinical Medicine Shaanxi University of Chinese MedicineXianyang 712046China Department of Gastroenterology Shaanxi Hospital of Traditional Chinese MedicineXi’an 710003China

Objective:To explore the mechanism of Yiyi Fuzi Baijiang p owder in treatment of ulcerative colitis in Coix Lacryma-jobi based on network pharmacology and molecular docking ***:Search for Yiyi Fuzi Baijiang powder’s active ingredient by traditional Chinese medicine database and analysis platform system pharmacology,Genecards,Uniprot database and Cytoscape software were used to construct the active component-ulcerative colitis disease target network,and gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis was performed,Autodock Vina was used for molecular docking ***:Quercetin,luteolin,kaempferol,chrysin,macroanol B,β-sitosterol,stigmasterol,deltoan and rhizoctonine may play a role in the treatment of ulcerative *** pathway enrichment analysis showed that Yiyi Fuzi Baijiang p owder mainly involved i nterleukin-17 signaling pathway and cancer pathway,among which the key targets were PTGS2,HSP90AA1 and CASP3 and had a good binding activity with 10 main active ***:The treatment of ulcerative colitis by Yiyi Fuzi Baijiang p owder may be mainly through quercetin,luteolin,macroanol B,β-sitosterol and other chemical components involved in cancer pathway,i nterleukin-17 signaling pathway acting on PTGS2,HSP90AA1,CASP3 and other disease targets in response to inorganic substances,response to cytokines and other biological processes f actor receptor binding and other molecular functions to achieve the purpose of treating u lcerative colitis.

关键词： Yiyi Fuzi Baijiang powder ulcerative colitis network pharmacology signal pathway molecular docking

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Ultrafast multi-target control of tightly focused light fields

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Opto-Electronic Advances 2022年第3期5卷 76-87页

作者： Yanxiang Zhang Xiaofei Liu Han Lin Dan Wang Ensi Cao Shaoding Liu Zhongquan Nie Baohua Jia Key Lab of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi ProvinceCollege of Physics and OptoelectronicsTaiyuan University of TechnologyTaiyuan 030024China Department of Physics Harbin Institute of TechnologyHarbin 150001China Centre of Translational Atomaterials(CTAM) Faculty of ScienceEngineering and TechnologySwinburne University of TechnologyHawthornVIC 3122Australia

The control of ultrafast optical field is of great interest in developing ultrafast optics as well as the investigation on vari-ous light-matter interactions with ultrashort ***,conventional spatial encoding approaches have only lim-ited steerable targets usually neglecting the temporal effect,thus hindering their broad *** we present a new concept for realizing ultrafast modulation of multi-target focal fields based on the facile combination of time-depend-ent vectorial diffraction theory with fast Fourier *** is achieved by focusing femtosecond pulsed light carrying vectorial-vortex by a single objective lens under tight focusing *** is uncovered that the ultrafast temporal de-gree of freedom within a configurable temporal duration(~400 fs)plays a pivotal role in determining the rich and exotic features of the focused optical field at one time,namely,bright-dark alternation,periodic rotation,and longitudinal/trans-verse polarization *** underlying control mechanisms have been *** being of academic in-terest in diverse ultrafast spectral regimes,these peculiar behaviors of the space-time evolutionary beams may underpin prolific ultrafast-related applications such as multifunctional integrated optical chip,high-efficiency laser trapping,micro-structure rotation,super-resolution optical microscopy,precise optical measurement,and liveness tracking.

关键词： ultrafast optical field vectorial diffraction theory fast Fourier transform vectorial vortex beam space-time shaping

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Weak Expansive Soil Physical Properties Modification by Means of a Cement-Jute Fiber

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Fluid Dynamics & Materials Processing 2023年第8期19卷 2119-2130页

作者： Zisheng Yang Wendong Li Xuelei Cheng Ran Hai Shunqun Li School of Architectural and Civil Engineering Zhongyuan University of TechnologyZhengzhou450007China Yellow River Institute of Hydraulic Research Zhengzhou450003China School of Civil Engineering Tianjin Chengjian UniversityTianjin300384China

Sixteen groups of comprehensive tests have been conducted to investigate the modifications in the physical properties of a weak expansive soil due to the addition of a cement jute *** tests have been conducted to analyze the liquid plastic limit,the particle distribution and the free expansion *** results show that:(1)With an increase in the cement-jute fiber content,the free expansion rate of the modified expansive soil gradually decreases,however,such a rate rebounds when the fiber content exceeds 0.5%and the cement content exceeds 6%.(2)With an increase in the cement percentage,the particle unevenness coefficient(Cu)and curvature coefficient(Cc)of the modified expansive soil tend to grow *** Cc coefficient reaches 1.0 when the cement content is 6%.The unevenness coefficient of 16 soil samples is greater than 5.0,however,the Cu coefficient decreases when the cement content reaches 6%.(3)The plastic limit of soil increases as the cement content is made higher,while the liquid limit and plastic index decrease *** the content of the modified material is 2%+0.1%~2%+0.7%(Cement content+jute fiber content),the change of particle size distribution is most obvious.(4)When the contents of cement and jute fiber are is 6%and 0.5%,respectively,the modification induced in the physical properties of soil samples corresponds to the best case.

关键词： Cement jute fiber expansive soil expansion optimal dosage

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A HPLC-Q-TOF-MS-based Urinary Metabolomic Approach to Identification of Potential Biomarkers of Metabolic Syndrome

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2014年第2期34卷 276-283页

作者：于智睿宁宇于浩汤乃军 Department of Occupational and Environmental Health Tianjin Medical University Tianjin Entry-Exit Inspection and Quarantine Bureau Offshore Oil Centers for Disease Control and Prevention

Metabolic syndrome （MetS） is a serious threat to public health worldwide with an increased risk of developing type 2 diabetes, cardiovascular diseases and all-cause morbidity and mortality. In this study, a urinary metabolomic approach was performed on high performance liquid chromatography quadrupole time-of-flight mass spectrometry to discriminate 36 male MetS patients and 36 sex and age matched healthy controls. Pattern recognition analyses （principal component analysis and orthogonal projections to latent structures discriminate analysis） commonly demonstrated the difference between MetS patients and no-MetS subjects. This study found 8 metabolites that showed significant changes in patients with MetS, including branch-chain and aromatic amino acids （leucine, tyrosine, phenylalanine and tryptophan）, short-chain acylcanitine （tiglylcamitine）, tricarboxylic acid （TCA） cycle intermediate （cis-aconitic acid） and glucuronidated products （cortolone-3-glucuronide and tetrahydroaldoster- one-3-glucuronide）. The candidate biomarkers revealed in this study could be useful in providing clues for further research focusing on the in-depth investigation of the cause of and cure for MetS.

关键词： metabolic syndrome metabolomics HPLC-Q-TOF-MS urine biomarker

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Dynamic numerical simulation on grinding medium flow field for vibration mill under various vibrating amplitude–frequency combination conditions

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International Journal of Modeling, Simulation, and scientific Computing 2015年第1期6卷 65-77页

作者： Xiaolan Yang Jifeng Liu Xuan Zhang Shangwei Cheng College of Mechanical Engineering Nanjing Institute of Technology 210013 P.R.China

People gained limited progress on refinement of super-hard powder using the vibration mill for many *** to various amplitude–frequency combination working conditions of vibration mill prototype,simulation research on dynamic characteristic of grinding medium flow field based on PFC is proposed in the paper,and a dynamics model of grinding medium flow field in barrel is ***,trajectory image of medium flow,kinetic energy and strain energy and collision frequency can be *** simulation analysis shows that collision between media as well as between media and the barrel can cause the changes of kinetic energy and strain energy of grinding medium flow under various amplitude–frequency combination conditions,and an energy-lacking region exists in the *** experiments under various working conditions show that kinetic energy and strain energy of grinding medium flow have large increment and energy-lacking regions become smaller,and then energy consumption decreases on working condition of high-amplitude and *** conclusion has practical value to refine powder by high-intensity vibration mill with certain frequency.

关键词： Grinding medium flow field numerical simulation vibration intensity amplitude-frequency combination energy consumption

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Encapsulation of Immature Somatic Embryos of Coffea arabica *** in Vitro Preservation

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Phyton-International Journal of Experimental Botany 2021年第6期90卷 1741-1748页

作者： Eliana Arias-Pérez Carlos Alberto Lecona-Guzmán Federico Antonio Gutiérrez-Miceli Joaquín Adolfo Montes-Molina Nancy Ruiz-Lau Laboratorio de Biotecnología Vegetal Instituto Tecnológico de Tuxtla GutiérrezTecnológico Nacional de MéxicoTuxtla GutiérrezChiapas29050México CONACYT-Tecnológico Nacional de México/Instituto Tecnológico de Tuxtla Gutiérrez Tuxtla GutiérrezChiapas29050México

The present study aimed to develop a protocol for somatic embryogenesis and encapsulation of coffee embryos(Coffea arabica L.),for the conservation of genotypes with characteristics of commercial *** embryos were induced from leaf explants in Murashige and Skoog medium(MS)supplemented with 1 mg·L^(−1) of 2,4-dichlorophenoxiacetic acid(2,4-D)combined with 2 mg·L^(−1) of benzyladenine(BA).Somatic embryos(SE)at the globular stage were encapsulated in a sodium alginate matrix;two treatments were tested:MS+5 mg·L^(−1) BA+1 mg·L^(−1) NAA+3%(w/v)alginate,and MS+7 mg·L^(−1) BA+5.7 mg·L^(−1) indoleacetic acid(IAA)+3%(w/v)*** was complexed with 100 mM calcium chloride(CaCl_(2)).Viability of the encapsulated SE was determined by staining with 0.01%fluorescein diacetate(FDA)after 0,15,30,and 45 days of storage at 4℃.Embryo viability was 100%in both treatments.

关键词： Coffee explants embryo artificial seeds

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Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme

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Bioactive Materials 2023年第5期23卷 45-52页

作者： Yi Xiao Haomin Yi Jingzhi Zhu Suhua Chen Guofang Wang Yilong Liao Yuanyuan Lei Liyin Chen Xingcai Zhang Fangfu Ye School of Engineering and Applied Sciences Harvard UniversityCambridgeMA02138USA Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province Department of PharmacySchool of MedicineHunan Normal UniversityChangsha410013HunanChina Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhouZhejiang325000China Hunan Provincial Maternal and Child Health Care Hospital Changsha410008HunanChina Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing100190China School of Engineering Massachusetts Institute of TechnologyCambridgeMA02139USA

Toxicity assessment is a major problem in pharmaceutical candidates and industry chemicals ***,due to the lack of practical analytical methods for DNA adduct analysis,the safety evaluation of drug and industry chemicals was severely ***,we develop a DNAzyme-based method to detect DNA adduct damage for toxicity assessment of drugs and *** 18 structural variants of G4 DNAzyme,EA2 DNAzyme exhibits an obvious DNA damaging effect of styrene oxide(SO)due to its unstable *** covalent binding of SO to DNAzyme disrupts the Hoogsteen hydrogen bonding sites of G-plane guanines and affects the formation of the G4 *** damage chemicals reduce the peroxidase activity of the G4 DNAzyme to monitor the DNA adduct damage by disrupting the structural integrity of the G4 *** method for genotoxic assessment of pharmaceutical candidates and industrial chemicals can elucidate the complex chemical pathways leading to toxicity,predict toxic effects of chemicals,and evaluate possible risks to human health.

关键词： Toxicity assessment DNAzyme DNA adduct Damage Styrene oxide Pharmaceutical candidates

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Gastrointestinal digestive fate of whey protein isolate coated liposomes loading astaxanthin:Lipolysis,release,and bioaccessibility

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Food Bioscience 2022年第1期45卷 115-121页

作者： Li Pan Hua Li Lifen Hou Zhengang Chang Yuanyuan Li Xueqin Li College of Food Science and Engineering Henan University of TechnologyZhengzhouChina Department of International Trade Henan Jingu Industry Development Co.LtdZhengzhouChina School of Chemistry and Chemical Engineering Henan University of TechnologyZhengzhouChina

Whey protein isolate coated astaxanthin-loaded liposomes were prepared in this *** gastrointestinal digestive fate of whey protein isolate coated astaxanthin-loaded liposomes was evaluated in terms of particle size,size distribution,zeta potential,and morphology during in vitro digestion as a function of *** on the particle size and morphology of whey protein isolate coated astaxanthin-loaded liposomes showed that the majority of particles maintained spherical shape with a progressive increase of particle size after passage through the *** zeta potential on whey protein isolate coated astaxanthin-loaded liposomes became highly negative after *** compared in uncoated liposomes,the astaxanthin release in whey protein isolate coated liposomes was slower in simulated gastric fluid digestion,while was faster in simulated intestinal fluid *** in vitro digestion,the bioaccessibility of astaxanthin was improved significantly after whey protein isolate *** was also found that the whey protein isolate coating could protect liposomes against destruction and suppress the lateral mobility of pyrene,resulting in lower micropolarity and fluidity of liposomal membrane during the *** findings may guide the potential application of whey protein isolate coated liposomes for improving the bioaccessibility and stability of astaxanthin in nutraceuticals and pharmaceutics.

关键词： Astaxanthin Liposomes Whey protein isolate coating Release Lipolysis Bioaccessibility

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