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Revisiting thermal comfort and thermal sensation

Building Simulation 2024年第2期17卷 185-188页

作者： Zhiwei Lian Department of Architecture Shanghai Jiao Tong UniversityShanghai200240China

The thermal environment is closely intertwined with comfort,health,efficiency,and building energy *** Comfort stands as a crucial concept for evaluating the thermal environment,yet the prevailing evaluation metric is Thermal *** correspondence between genuine Thermal Comfort and Thermal Sensation is influenced by a variety of environmental factors.

关键词： thermal Comfort prevailing

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Nanophotonics in China： Overviews and highlights

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Frontiers of physics 2012年第6期7卷 601-631页

作者： Zhi-Yuan Li Laboratory of Optical Physics Institute of PhysicsChinese Academy of SciencesP.O.Box 603Beijing 100190China

The major purpose of this paper is to present a brief overview of the history and the current status of nanophotonics research in China, and to highlight some research results in the past years made by the Chinese nanophotonics communities. I will first briefly introduce the principles of nanophotonics and several of its major disciplines including photonic crystals, plasmonics and metamaterials, and related artificial acoustic structures. Then I will highlight some major progresses made by Chinese research groups in these areas with the selection made merely based on my personal taste. The aim is to let these results better known and appreciated by researchers in the Chinese communities of nanophotonics and related areas, and provide better opportunities of researchers in different areas to have more communications. I also hope that this brief introduction will help to make a better bridge to connect Chinese nanophotonics communities with the broader communities in the world.

关键词： nanophotonics photonic crystals plasmonics metamaterials phononic crystals

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PDK1 plays a critical role in regulating cardiac function in mice and human

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Chinese Medical Journal 2010年第17期123卷 2358-2363页

作者： DI Ruo-min FENG Qiu-ting CHANG Zai LUAN Qing ZHANG Yang-yang HUANG Jun LI xin-li YANG Zhong-zhou Department of Cardiology First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu 210029 China MOE Key Laboratory of Model Animal for Disease Study Model Animal Research Center of Nanjing University Nanjing Jiangsu 210061 China

Background PDK1 is an essential protein kinase that plays a critical role in mammalian development. Mouse lacking PDK1 leads to multiple abnormalities and embryonic lethality at E9.5. To elucidate the role of PDK1 in the heart, we investigated the cardiac phenotype of mice that lack PDK1 in the heart in different growth periods and the alteration of PDK1 signaling in human failing *** We employed Cre/loxP system to generate PDK1flox/flox： α-MHC-Cre mice, which specifically deleted PDK1 in cardiac muscle at birth, and tamoxifen-inducible heart-specific PDK1 knockout mice （PDK1flox/flox：MerCreMer mice）, in which PDK1 was deleted in myocardium in response to the treatment with tamoxifen. Transmural myocardial tissues from human failing hearts and normal hearts were sampled from the left ventricular apex to analyze the activity of PDK1/Akt signaling pathways by Western *** PDK1flox/flox： α-MHC-Cre mice died of heart failure at 5 and 10 weeks old. PDK1flox/flox-MerCreMer mice died of heart failure from 5 to 21 weeks after the initiation of tamoxifen treatment at 8 weeks old. We found that expression levels of PDK1 in human failing heart tissues were significantly decreased compared with control *** Our results suggest that PDK1 signaling network takes part in regulating cardiac viability and function in mice, and may be also involved in human heart failure disease.

关键词： PDK1 Akt heart failure

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