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Impact of Spinal Manipulative Therapy on Brain Function and Pain Alleviation in Lumbar disc Herniation:A resting-State fMrI Study

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Chinese Journal of Integrative Medicine 2025年第2期31卷 108-117页

作者： ZHOU Xing-chen WU Shuang WANG Kai-zheng CHEN Long-hao WEI Zi-cheng LI Tao HUA Zi-han XIA Qiong LYU Zhi-zhen LYU Li-jiang department of Spine The Third Affiliated Hospital of Zhejiang Chinese Medicine UniversityHangzhou(310053)China department of Spine The Third School of Clinical MedicineZhejiang Chinese Medicine UniversityHangzhou(310053)China research Institute of Tuina(Spinal disease) Zhejiang Chinese Medicine UniversityHangzhou(310053)China

Objective:To elucidate how spinal manipulative therapy(SMT)exerts its analgesic effects through regulating brain function in lumbar disc herniation(LdH)patients by utilizing resting-state functional magnetic resonance imaging(rs-f MrI).Methods:From September 2021 to September 2023,we enrolled LdH patients(LdH group,n=31)and age-and sex-matched healthy controls(HCs,n=28).LdH group underwent rs-f MrI at 2 distinct time points(TPs):prior to the initiation of SMT(TP1)and subsequent to the completion of the SMT sessions(TP2).SMT was administered once every other day for 30 min per session,totally 14 treatment sessions over a span of 4 *** did not receive SMT treatment and underwent only one f MrI ***,participants in LdH group completed clinical questionnaires on pain using the Visual Analog Scale(VAS)and the Japanese Orthopedic Association(JOA)score,whereas HCs did not undergo clinical scale *** effects on the brain were jointly characterized using the amplitude of low-frequency fluctuations(ALFF)and regional homogeneity(re Ho).Correlation analyses were conducted between specific brain regions and clinical ***:Following SMT treatment,pain symptoms in LdH patients were notably alleviated and accompanied by evident activation of effects in the *** comparison to TP1,TP2 exhibited the most significant increase in ALFF values for Temporal_Sup_r and the most notable decrease in ALFF values for Paracentral_Lobule_L(voxelwise Prs>30;Fdr correction).Additionally,the most substantial enhancement in re Ho values was observed for the Cuneus_r,while the most prominent reduction was noted for the Olfactory_r(voxelwise Prs>30;Fdr correction).Moreover,a comparative analysis revealed that,in contrast to HCs,LdH patients at TP1 exhibited the most significant increase in ALFF values for Temporal_Pole_Sup_L and the most notable decrease in ALFF values for Frontal_Mid_L(voxelwise Prs>30;Fdr correction).Fur

关键词： functional magnetic resonance imaging lumbar disc herniation spinal manipulative therapy pain

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Nanosheet-doped Polymer Composites with High Intrinsic Piezoelectric Properties for Energy Harvesting

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Energy & Environmental Materials 2025年第01期8卷 125-136页

作者： Kaihang Zhang Jiaqi Lu Xinyu Cai Muhammad Naeem Shah Jianhui Wu Jie Li Yifan Wu Chi Zhang Liangquan Xu Haoze Kuang dinku Hazarika Binghan Zhou Zhuo Chen Zhen Cao Hao Jin Shurong dong Yuhui Huang Qilong Zhang Yongjun Wu Luigi Giuseppe Occhipinti Tawfique Hasan Jikui Luo College of Information Science and Electronic Engineering Zhejiang University International Campus Zhejiang University 2nd Affiliated Hospital School of Medicine Zhejiang University Cambridge Graphene Centre Department of Engineering University of Cambridge School of Materials Science and Engineering Zhejiang University Key Lab of CS&AUS of zhejiang province Zhejiang University

Few-layer nanosheets(NSs) of hexagonal boron nitride(h-BN) and molybdenum disulfide(MoS2) display notable piezoelectric ***,their integration into polymers typically yields non-piezoelectric composites due to NSs' random *** introduce a facile method for fabricating intrinsic piezoelectric composites incorporated with NSs without electric *** innovative process aligns NSs within polyvinyl alcohol polymer,leveraging ice-water interfacial tension,water crystallization thrust,and directional cross-linking during freezing.

关键词： nanoscale alignment process piezoelectric composite piezoelectric transducers and sensors vertically aligned NSs

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AI-Enhanced Secure data Aggregation for Smart Grids with Privacy Preservation

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Computers, Materials & Continua 2025年第1期82卷 799-816页

作者： Congcong Wang Chen Wang Wenying Zheng Wei Gu School of Software Nanjing University of Information Science and TechnologyNanjing210044China School of Information Science and Engineering Zhejiang Sci-Tech UniversityHangzhou310018China State Key Laboratory of Public Big data Guizhou UniversityGuiyang550025China School of Computer Science and Technology(School of Artificial Intelligence) Zhejiang Sci-Tech UniversityHangzhou310018China School of Computer Science(School of Cyber Science and Engineering) Nanjing University of Information Science and TechnologyNanjing210044China

As smart grid technology rapidly advances,the vast amount of user data collected by smart meter presents significant challenges in data security and privacy *** research emphasizes data security and user privacy concerns within smart ***,existing methods struggle with efficiency and security when processing large-scale *** efficient data processing with stringent privacy protection during data aggregation in smart grids remains an urgent *** paper proposes an AI-based multi-type data aggregation method designed to enhance aggregation efficiency and security by standardizing and normalizing various data *** approach optimizes data preprocessing,integrates Long Short-Term Memory(LSTM)networks for handling time-series data,and employs homomorphic encryption to safeguard user *** also explores the application of Boneh Lynn Shacham(BLS)signatures for user *** proposed scheme’s efficiency,security,and privacy protection capabilities are validated through rigorous security proofs and experimental analysis.

关键词： Smart grid data security privacy protection artificial intelligence data aggregation

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N-doped Cu_(2)O with the tunable Cu^(0)and Cu^(+)sites for selective CO_(2)electrochemical reduction to ethylene

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Journal of Environmental Sciences 2025年第4期150卷 246-253页

作者： Yao Shen Liuqing Qian Qianqian Xu Shilun Wang Yong Chen Hengxia Lu Yu Zhou Jiexu Ye Jingkai Zhao Xiang Gao Shihan Zhang College of Environment Zhejiang University of TechnologyHangzhou 310014China Institute of Energy and Sustainable development Zhejiang University of TechnologyHangzhou 310014China

The electrochemical carbon dioxide reduction reaction(CO_(2)rr)to high value-added fuels or chemicals driven by the renewable energy is promising to alleviate global ***,the selective CO_(2)reduction to C_(2)products remains ***-based catalyst with the specific Cu^(0)and Cu^(+)sites is important to generate C_(2)*** work used nitrogen(N)to tune amounts of Cu^(0)and Cu^(+)sites in Cu_(2)O catalysts and improve C_(2)-product *** controllable Cu^(0)/Cu^(+)ratio of Cu_(2)O catalyst from 0.16 to 15.19 was achieved by adjusting the N doping amount using NH3/Ar plasma *** major theme of this work was clarifying a volcano curve of the ethylene Faraday efficiency as a function of the Cu^(0)/Cu^(+)*** optimal Cu^(0)/Cu^(+)ratio was determined as 0.43 for selective electroreduction CO_(2)to ethylene.X-ray spectroscopy and density functional theory(dFT)calculations were employed to elucidate that the strong interaction between N and Cu increased the binding energy of N–Cu bond and stabilize Cu^(+),resulting in a 92.3%reduction in the potential energy change for^(∗)CO-^(∗)CO *** study is inspiring in designing high performance electrocatalysts for CO_(2)conversion.

关键词： CO_(2)electroreduction Cu^(0)/Cu^(+)ratio Nitrogen doping Ethylene Theoretical calculation

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Volatile flavor analysis of flesh oil and liver oil from doederleinia berycoides based on HS-GC-IMS,HS-SPME-GC-MS and lipidomics

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Grain & Oil Science and Technology 2025年第1期8卷 1-12页

作者： Feifan Wu Kewei Lin Jixiang Zhang Xinyang Li Xiaoguo Ying Shanggui deng Alessandra Guidi Gengsheng Xiao Feng Wang Lukai Ma Food Science and Pharmacy Zhejiang Ocean UniversityZhoushan 316022China College of Light Industry and Food Zhongkai University of Agriculture and Engineering/Key Laboratory of Green Processing and Intelligent Manufacturing of Lingnan Specialty FoodMinistry of Agriculture and Rural Affairs/Guangdong Provincial Key Laboratory of Lingnan Specialty Food Science and TechnologyGuangzhouChina department of Agriculture Food and Environment(DAFE)Pisa UniversityVia Del Borghetto8056124PisaItaly

Edible oils derived from aquatic products are rich in lipids beneficial to human ***,the volatile flavor characteristics of flesh oil and liver oil from doederleinia berycoides remain *** this study,flesh oil and liver oil were extracted from doederleinia berycoides,revealing different fatty acid compositions and *** analysis identified a total of 124 differential lipids between the flesh oil and liver oil,including 42 glycerophospholipids(GPs),33 glycerolipids(GLs),23 free fatty acids(FAs),13 sphingolipids(SPs),10 sterols(STs),and 3 prenol lipids(Prs).Analysis using HS-GC-IMS identified 12 key volatile compounds that significantly contributed to the distinct volatile flavors of the flesh and liver *** volatile flavors originated from these volatile compounds,which had different relative Odor Activity Values(rOAVs).Further results from HSSPME-GC-MS showed that the volatile flavors of the flesh oil and liver oil were respectively attributed to 64 and 35 volatile compounds,each with unique key volatile compounds exhibiting different *** were significant positive or negative correlations between 18 key differential lipids and 24 volatile compounds in both flesh oil and liver ***,the complex lipid profiles are responsible for the unique volatile flavors of flesh oil and liver oil,and the differential lipids play a central role in their volatile flavor *** findings provide a foundation for understanding the volatile flavor differences in fish oils and hold promise for further exploration of the molecular mechanisms underlying oil volatile flavors.

关键词： Flesh oil Liver oil Lipids Volatile compounds Volatile flavors

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HAG1 regulates Arsenic Allocation and Accumulation in rice Grains

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rice science 2025年第1期32卷 1-5,I0001-I0009页

作者： YANG Huan YU Jing XIE Manyi XU Ping CAO Zhenzhen CHEN Mingxue CAO Zhaoyun rice Product Quality Inspection and Supervision Center Ministry of Agriculture and Rural AffairsChina National Rice Research InstituteHangzhou 310006China

rice is a well-recognized accumulator of arsenic(As),which poses a threat to food security and human *** rice varieties vary widely in their As accumulation and tolerance,yet the underlying genetic basis remains *** this study,we isolated a rice mutant hag1,which displayed high accumulation of As in rice grains and increased sensitivity to As *** genetic investigation,we identified the ATP-binding cassette(ABC)transporter OsABCC1,involved in sequestering As in vacuoles,as the causal gene responsible for As allocation and tolerance in *** physiological analysis revealed that As stress caused more severe oxidative damage in hag1 compared with the wild type(WT).The hag1 mutant displayed different accumulation patterns depending on the levels of As *** discovered that under low As concentration,hag1 synthesized more thiol compounds and exhibited lower As translocation than the WT;however,at high As levels,hag1 produced fewer thiol compounds and increased As transfer *** analysis of the node nearest to the panicles revealed that OsABCC1 was down-regulated in hag1,resulting in increased As translocation and accumulation in rice ***,natural variations in the promoter of OsABCC1 may confer differential gene expression and distinct As accumulations in grains between japonica and indica rice varieties,providing insights for breeding low-As rice varieties.

关键词： breeding grains insight

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The coordinated interaction or regulation between floral pigments and volatile organic compounds

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Horticultural Plant Journal 2025年第2期11卷 463-485页

作者： Yueqing Li Tingting Bao Jia Zhang Hongjie Li Xiaotong Shan Huijun Yan Shadrack Kimani Liangsheng Zhang Xiang Gao Key Laboratory of Molecular Epigenetics of MOE Northeast Normal UniversityChangchunJilin130024China Genomics and Genetic Engineering Laboratory of Ornamental Plants College of Agriculture and BiotechnologyZhejiang UniversityHangzhouZhejiang310058China Flower research Institute of Yunnan Academy of Agricultural Sciences KunmingYunnan650205China School of Pure and Applied Sciences Karatina UniversityKaratina 10101Kenya

Floral color and scent are crucial for plant-environment interactions,especially in reproduction by attracting pollinators for *** also have wide applications in cosmetic,pharmaceutical,and nutraceutical *** pigments are typically classified as chlorophylls,flavonoids,carotenoids,and betalains,while volatile organic compounds(VOCs)are grouped as terpenes,phenylpropanoids/benzenoids,and fatty acid *** progresses have been made in understanding the biosynthesis and regulation of these floral pigments and *** differences in their biosynthetic pathways,floral pigments and VOCs are biochemically connected and exhibit synergistic interactions during flower development and in response to biotic and abiotic stresses,suggesting the existence of pleiotropic regulators or complex mechanisms co-regulating their *** this review,we summarize and outline the metabolite pathways mainly integrating flavonoids,carotenoids,terpenes,and phenylpropanoids/*** also provide a series of scenarios illustrating the coordinated regulation of floral color and ***,we suggest areas for future *** hope this review will spark interest in this research direction and stimulate further studies.

关键词： Color and scent Co-regulation Pleiotropic regulators Promoter analysis Specialized metabolites

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Preparation and study of novel mid-to-low-temperature phase-change molten salts

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Science China(Technological Sciences) 2025年第2期68卷 53-64页

作者： Chenxing rEN Yifan WANG Xin HE Chenghang ZHENG Xiang GAO State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou 310027China Institute of Carbon Neutrality Zhejiang UniversityHangzhou 310027China Baima Lake Laboratory Zhejiang UniversityHangzhou 310051China

Molten salts is a promising medium for heat storage and heat transfer due to their advantages of low cost,low steam pressure,high energy storage density and wide temperature *** this paper,a new phase change mixture of molten salts with KNO_(3),NaNO_(3),ZnCl_(2),NaF,Na_(2)CO_(3),NaCl,and MgO as materials has been prepared through a plenty of *** experimental results show that the melting point of some molten salts can be reduced to 202.9℃,and the decomposition temperature can reach 701.3℃.In addition,its thermophysical properties,including specific heat,viscosity and thermal stability,were measured and *** average specific heat of some molten salts is as high as 2.53 J/(g K),and the average thermal conductivity is as high as 0.77 W/(m K).In the 4-day short-term thermal stability test,the fluctuation of each parameter is minimal,and the overall thermal physical property is relatively *** with the traditional phase change molten salt,the new hybrid molten salt has a significantly lower melting point,a further improvement in the decomposition temperature,specific heat and other comprehensive thermophysical properties,and a better overall economy,which has important application value in heat transfer and energy storage.

关键词： molten salts renewable energy consumption heat transfer and heat storage thermal stability

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Numerical Analysis of the Influence of Liquid Cooling Flow Space on the Assessment of Thermal Management of PEMFC

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Energy Engineering 2025年第3期122卷 1025-1051页

作者： Abubakar Unguwanrimi Yakubu Jiahao Zhao Qi Jiang Xuanhong Ye Junyi Liu Qinglong Yu Shusheng Xiong College of Energy Engineering Zhejiang UniversityHangzhou310027China College of Agriculture and Environmental Science Kaduna State UniversityKaduna800283Nigeria Longquan Industrial Innovation research Institute Longquan323700China Provincial Key Laboratory of New Energy Vehicles Thermal Management Longquan323700China

This study uses numerical simulations of liquid cooling flow fields to investigate polymer exchange membrane fuel cell(PEMFC)thermal *** research shows that the optimum cooling channel design significantly reduces the fuel cell’s temperature differential,improving overall ***,the simulations show a reduction in the maximum temperature by up to 15%compared to traditional ***,according to analysis,the Nusselt number rises by 20%with the implementation of serpentine flow patterns,leading to enhanced heat transfer *** findings demonstrate that effective cooling strategies can lead to a 10% increase in fuel cell performance under varying operational conditions,including pressures of 2 bar and relative humidity levels of 30%,60%,and 80%.These results underscore the importance of cooling flow design in optimizing PEMFC performance.

关键词： Thermal management flow field design heat transfer coolant channels electrochemical reaction

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Great influence of demagnetization history on internal interaction and magnetization process of mischmetal-based magnets

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Science China(Physics,Mechanics & Astronomy) 2025年第2期68卷 183-192页

作者： dan Liu Jiefu Xiong Lichen Wang Xinqi Zheng Xin Ming Jiaying Jin Jiazheng Hao He Bai Zhenxing Li Tongyun Zhao Fengxia Hu Jirong Sun Jun Shen Baogen Shen department of Physics Beijing Technology and Business UniversityBeijing 10048China Ningbo Institute of Materials Technology&Engineering Chinese Academy of SciencesNingbo 31521China School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China Spallation Neutron Source Science Center Dongguan 523803China School of Mechanical Engineering Beijing Institute of Technology Beijing 100081China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 101408China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China

The magnetization process and corresponding magnetization curve are usually used to analyze the coercivity mechanism of NdFe-B based sintered ***,different demagnetization histories will seriously influence the magnetization curve,leading to an inaccurate understanding and analysis of magnetization *** this work,we investigated the magnetization behavior of multi-main phase(MMP)magnets with thermal demagnetized and alternating current demagnetized *** curves of initial magnetization process and demagnetization process of thermal demagnetized magnets reflect the movement of domain walls inside the grains and the magnetization interaction between the grains,*** is noted that the former process cannot represent the magnetization reversal of the entire magnet,which is not appropriate to analyze coercivity mechanism *** the recoil curves of both two processes of AC demagnetized magnets can illustrate the magnetization reversal of the entire grains and the interaction between ***-optical Kerr microscope shows that the grains of thermal demagnetized magnets are in multi-domain states,and the grains of AC demagnetized magnets are almost in singledomain *** walls of thermal demagnetized magnets move easily within the grains,which is more conducive to magnetization saturation in industrial *** addition,the minorloops of thermal demagnetized magnets can independently represent the transition of grains from multi-domain to single-domain and the demagnetization of single-domain grains,which is equivalent to characterizing the internal interactions by recoil *** investigation of magnetization characteristics of MMP sintered magnets starting from different demagnetized states is helpful to further understand the internal interaction and magnetic hardening mechanism.

关键词： permanent magnet demagnetization history magnetization reversal misch-metal rare earth

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