检索结果-南通市图书馆

Airway Management for Cervical Spinal Cord Injury

在线全文

cnki会议

学校读者我要写书评

暂无评论

Airway Management for Cervical Spinal Cord Injury

2008年第七次华东六省一市麻醉学学术会议暨浙江省麻醉学术年会

作者： Chuanyao tong~*,MD,Yingtian Wang,MD# ~*(presenting author)department of anesthesiology,Wake Forest university school of medicine,Winston-Salem,North Carolina,USA # department of anesthesiology,shanghai First People’s hospital,shanghai,china

Introduction:The incidence of cervical spine injury(cSCI)is about 2%in all blunt trauma,8-10%in patient of GCS<*** causes of SCI are MVA(40-50%),fall(20%,most in elderly),sports and recreation (7-15%),gunshot(2-5%),ia...

Introduction:The incidence of cervical spine injury(cSCI)is about 2%in all blunt trauma,8-10%in patient of GCS3)identification of high-risk recreational

关键词：

Regulated expression of TATA-binding protein-related factor 3(TRF3)during early embryogenesis

在线全文

cnki会议

学校读者我要写书评

暂无评论

Cell Research 2006年第07期16卷 8+611-621页

作者： Ye Yang~1 Jian Cao~1 Lu Huang~1 Hai Yan Fang~2 Hui Zhen Sheng~(1,2) ~1Laboratory of Stem Cell Biology,Institute of Biochemistry and Cell Biology,shanghai Institutes.for Biological Sciences,Chinese Academy of Sciences,shanghai 200031 china ~2Center for Developmental Biology,Xinhua hospital,school of medicine,shanghai jiao tong university,1665 Kong Jiang Road,shanghai 200092,china LaboratoryofStemCellBiology InstituteofBiochemistryandCellBiologyShanghaiInstitutesforBiologicalSciencesChineseAcademyofSciencesShanghai200031China CenterforDevelopmentalBiology XinhuaHospitalSchoolofMedicine

RNA polymerase（Pol）Ⅱ transcription persists in TATA-box-binding protein（TBP）-/-mutant mouse embryos,indicat-ing TBP-independent mechanisms for Pol Ⅱ transcription in early ***-related factor3（TRF3）has beenproposed to substitute for TBP in TBP-/-mouse *** examined the expression of TRF3 in maturing oocytes andearly embryos and found that TRF3 was co-expressed with TBP in the meiotic oocytes and early embryos from the lateone-cell stage *** amounts of TBP and TRF3 changed dynamically and correlated well with *** immunoprecipitation（CHIP）assay revealed that different gene promoters in mouse embryonic stem（ES）cells recruited TRF3 and TBP *** analyses of TRF3 and TBP during cell cycle showed thatboth factors proceeded through cell cycle in a similar pace,except that TRF3 was slightly delayed than TBP in enteringthe nucleus when cells were exiting the *** from expression and biochemical analyses therefore support thehypothesis that TRF3 plays a role in early mouse *** addition,results from co-localization study suggestthat TRF3 may be also involved in Pol I transcription.

关键词： TBP TRF3 oocyte embryo ES cell NIH3T3 cell

成人阻塞性睡眠呼吸暂停诊断和外科治疗指南(2024)计划书

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中华耳鼻咽喉头颈外科杂志 2024年第2期59卷 114-121页

作者：中华耳鼻咽喉头颈外科杂志编辑委员会咽喉组中华医学会耳鼻咽喉头颈外科学分会咽喉学组、嗓音学组上海交通大学医学院附属第六人民医院上海市睡眠呼吸障碍疾病重点实验室殷善开中华耳鼻咽喉头颈外科杂志编辑委员会咽喉组中华医学会耳鼻咽喉头颈外科学分会咽喉学组、嗓音学组上海交通大学医学院附属第六人民医院上海市睡眠呼吸障碍疾病重点实验室上海市睡眠呼吸障碍疾病重点实验室

阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)是一种常见的慢性睡眠呼吸障碍疾病,可引起全身系统性损伤,导致沉重的社会经济负担。在OSA诊断(包括筛查)领域尚存在诸多未明确的问题,包括各种筛查诊断工具在OSA早发现及早诊断中的作... 详细信息

阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)是一种常见的慢性睡眠呼吸障碍疾病,可引起全身系统性损伤,导致沉重的社会经济负担。在OSA诊断(包括筛查)领域尚存在诸多未明确的问题,包括各种筛查诊断工具在OSA早发现及早诊断中的作用,对部分特殊人群进行早期OSA筛查及规范诊断的必要性,以及合适筛查工具的确定等。随着新的筛查、诊断技术的不断涌现和国际新标准的相继出台,目前的OSA诊断指南需要进一步的完善和更新。外科手术是OSA重要治疗方法,而这方面国内鲜有可用于指导临床实践的高质量指南共识。因此,结合国内外的循证证据构建规范化OSA诊断和外科治疗指南对于更好地指导当前OSA的临床实践至关重要。指南制订工作组将参考《世界卫生组织指南制订手册》,注册并撰写《成人阻塞性睡眠呼吸暂停诊断和外科治疗指南(2024)》计划书。本计划书主要介绍该指南制订的背景、意义、目的、人员组成,目标人群、干预措施、对比措施和结局指标(population、intervention、control、outcome,PICO)问题的确定,证据的获取及评价,以及推荐意见的形成等指南制订过程和具体方法。本计划书旨在为科学和循证制订本指南提供纲领性及指导性的实施方案。

关键词：阻塞性睡眠呼吸暂停诊断指南计划书目标人群筛查工具外科手术制订过程临床实践

维普期刊数据库

Acinic cell carcinoma of the parotid gland:MR features

在线全文

学校读者我要写书评

暂无评论

Acinic cell carcinoma of the parotid gland:MR features

The 9th Asian Congress of Oral and Maxillofacial Radiology

作者： Shi Huimin Wang Shaoying department of Radiology Ninth People’s hospital school of medicine shanghai jiao tong university

＜正＞Aims:To evaluate the diagnostic value of MR imaging feature and conventional contrast -enhanced MR imaging appearance in acinic cell carcinoma of the parotid gland. Methods:We retrospectively reviewed pre- and p...

关键词：

Antepartum hemorrhage from previous-cesarean-sectioned uterus as a potential sign of uterine artery pseudoaneurysm

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Zhejiang university-Science B(Biomedicine & Biotechnology) 2017年第5期18卷 441-444页

作者： Ning ZHANG Wei-hua LOU Xue-bin ZHANG Jian-hua LIN Wen DI department of Obstetrics and Gynecology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200126China department of lnterventional Oncology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200126China

目的:子宫动脉瘤多被认为与产程中创伤性操作相关,但近年陆续有报道显示子宫动脉瘤可发生于自然分娩过程中。本文将为自然分娩过程中子宫动脉瘤的发生和紧急处理等提供参考指导。创新点:产前出血可能是子宫动脉瘤发生的潜在危险信号。方... 详细信息

目的:子宫动脉瘤多被认为与产程中创伤性操作相关,但近年陆续有报道显示子宫动脉瘤可发生于自然分娩过程中。本文将为自然分娩过程中子宫动脉瘤的发生和紧急处理等提供参考指导。创新点:产前出血可能是子宫动脉瘤发生的潜在危险信号。方法:病例报道和文献汇纳分析。患者女,37岁,疤痕子宫,临产入院,产前出血,经阴顺产后12 h,突发阴道大量出血,常规对症处理(按摩子宫、阴道填塞、缩宫素静滴和欣母佩宫颈注射等)未能有效缓解,40 min内出血达1800 ml。床边B超未提示动脉瘤特征,数字减影血管造影(DSA)显示左侧子宫动脉瘤,即刻予动脉栓塞成功止血。患者产后4 d无并发症出院,随访无后遗症。结论:临床医师需要加强对子宫动脉瘤发生的警惕认识和急救处理水平。子宫动脉瘤和产程中的有创性操作无必然相关性,疤痕子宫的产前出血可能是子宫动脉瘤发生的潜在危险信号,产后随访应提高对晚期出血发生的警惕性。鉴于B超在诊断动脉瘤方面的有限性,高度怀疑动脉瘤时应尽快行血管造影明确诊断,及时栓塞处理。

关键词：子宫动脉瘤经阴分娩早期产后出血动脉栓塞

维普期刊数据库

Nuclear reprogramming: the zygotic transcription program is established through an“erase-and-rebuild” strategy

在线全文

学校读者我要写书评

暂无评论

Cell Research 2007年第2期17卷 117-134页

作者： Feng Sun~(1,*) Haiyan Fang~(2,*) Ruizhen Li~(2,*) Tianlong Gao~1 Junke Zheng~2 Xuejin Chen~2 Wenqin Ying~2 Hui Z Sheng~2 ~1Program for Graduation Studies,shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,shanghai 200031,china ~2Center for Developmental Biology,Xinhua hospital,school of medicine,shanghai jiao tong university,1665 Long Jiang Road,shanghai 200092,china ProgramforGraduationStudies ShanghaiInstitutesforBiologicalSciencesChineseAcademyofSciencesShanghai200031China CenterforDevelopmentalBiology XinhuaHospitalSchoolofMedicineShanghaiJiaoTongUniversity1665KongJian

Oocytes display a maternal-specific gene expression profile,which is switched to a zygotic profile when a haploidset of chromatin is passed on to the fertilized egg that develops into an *** mechanism underlying this tran-scription reprogramming is currently *** we demonstrate that by the time when transcription is shut downin germinal vesicle oocytes,a range of general transcription factors and transcriptional regulators are dissociated fromthe *** global dissociation of chromatin factors(CFs)disrupts physical contacts between the chromatin andCFs and leads to erasure of the maternal transcription program at the functional *** transcription factors andregulators remain separated from chromatin for a prolonged period,and become re-associated with chromatin shortlyafter pronuclear *** is followed temporally by the re-establishment of nuclear functions such as DNA rep-lication and *** propose that the maternal transcription program is erased during oogenesis to generatea relatively naive chromatin and the zygotic transcription program is rebuilt de novo after *** process istermed as the"erase-and-rebuild"process,which is used to reset the transcription program,and most likely other nuclearprocesses as well,from a maternal one to that of the *** further show in the accompanying paper(Gao T,et al.,Cell Res 2007:17:135-150.)that the same strategy is also employed to reprogram transcriptional profiles in somatic cellnuclear transfer and parthenogenesis,suggesting that this model is universally applicable to all forms of transcriptionalreprogramming during early *** of CFs from chromatin also offers an explanation for thephenomenon of transcription silence during the maternal to zygotic transition.

关键词： nuclear reprogramming transcription transcription silence chromatin factors embryogenesis fertilization oogenesis

OCULAR COMPLICATIONS IN ATOPIC DERMATITIS

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of shanghai Second Medical university(Foreign Language Edition) 2008年第1期20卷 54-59页

作者：沈玺徐格致焦秦李霞施若菲 department of Ophthalmology Ruijin Hospital School of Medicine Shanghai Jiaotong University department of Ophthalmology Eye Ear Nose and Throat Hospital School of Medicine Fudan University department of Dermatology Ruijin Hospital School of Medicine Shanghai Jiaotong University

Objective To describe the ocular complications of 62 patients with active atopic dermatitis (AD) during the period of 2003 2006. Methods Routine ophthalmic examinations, including slit-lamp microscope, indirect ophthalmoscope or Goldmann three-mirror lens, A-scan and B-scan ultrasound, ultrasound biomicroscope (UBM) and corneal topography, as well as tear film break-up time (BUT) and Schirmer tests were carried out. Results Cataract (28 eyes), keratoconjunctivitis (42 eyes), superficial punctate keratopathy (45 eyes) and tear function abnormality (76 eyes) were major ocular complications in AD patients. Retinal detachment (6 eyes) was the most severe ocular complication in the AD patients. Conclusion Ocular complications are common in AD patients and a very careful examination of eyes is essential in treating AD patients. If the eyes can be examed carefully and in time, some operations and severe complications can be avoidable, especially for the patients with retinal breaks or retinal detachment.

关键词： atopic dermatitis keratoconjunctivitis cataract retinal detachment ocularcomplications

维普期刊数据库

Granulocyte-macrophage colony-stimulating factor DNA prime-protein boost strategy to enhance efficacy of a recombinant pertussis DNA vac-cine

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2006年第11期27卷 1487-1494页

作者： Qing-tian LI~(2,3,5)Yong-zhang ZHU~(2,3,5)Jia-you CHU~(2,6)Ke DONG~3 Ping HE~3 Chun-yan FENG~3 Bao-yu HU~3 Shu-min ZHANG~4 Xiao-kui GUO~(3,6)2 Institute of Medical Biology,Peking Union Medical College and Chinese Academy of Medical Sciences,Kunming 650118,china 3 department of Medical Microbiology and Parasitology,shanghai jiao tong university school of medicine,shanghai 200025,china 4 Chinese National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050,china InstituteofMedicalBiology PekingUnionMedicalCollegeandChineseAcademyofMedicalSciencesKunming650118China departmentofMedicalMicrobiologyandParasitology ShanghaiJiaoTongUniversitySchoolofMedicineShanghai200025China

Aim:To investigate a new strategy to enhance the efficacy of a recombinantpertussis DNA *** strategy is co-injection with cytokine plasmids asprime,and boosted with purified homologous ***:A recombinantpertussis DNA vaccine containing the pertussis toxin subunit 1(PTS 1),fragmentsof the filamentous hemagglutinin(FHA)gene and pertactin(PRN)gene encodingfilamentous hemagglutinin and pertactin were ***/c mice were im-munized with several DNA vaccines and antigen-specific antibodies anti-PTS1,anti-PRN,anti-FHA,cytokines interleukin(IL)-10,IL-4,IFN-γ,TNF-α,and spleno-cyte-proliferation assay were used to describe immune ***:Therecombinant DNA vaccine could elicit similar immune responses in mice as that ofseparate plasmids encoding the 3 fragments,*** immunized withDNA and boosted with the corresponding protein elicited more antibodies thanthose that received DNA as *** particular,when the mice were co-immu-nized with murine granulocyte-macrophage colony-stimulating factor plasmidsand boosted with proteins,all 4 cytokines and the 3 antigen-specific antibodieswere significantly increased compared to the pVAX1 ***-PTS1,anti-FHA,IL-4 and TNF-α elicited in the colony stimulating factor(CSF)prime-proteinboost group showed significant increase compared to all the other ***:This prime and boost strategy has proven to be very useful in im-proving the immunogenicity of DNA vaccines against pertussis.

关键词： granulocyte-macrophage colony-stimulating factor pertussis DNA vaccines

MATERNAL CHRONIC STRESS AND FETAL SEX RATIO

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

MATERNAL CHRONIC STRESS AND FETAL SEX RATIO

中华医学会第十七次全国儿科学术大会

作者： Lisu Huang~1,Jun Zhang~1,Xiaodan Yu~1,JianXu~1,Fei Li~1,Jiangfeng Ye~1 1.1.MOE and shanghai Key Laboratory of Children’s Environmental Health,Xinhua hospital,shanghai jiaotong university school of medicine,shanghai,china 2.2.department of Pediatrics,Xinhua hospital,shanghai jiaotong university school of medicine,shanghai, china 3.3.department of Developmental and Behavioral Pediatrics,shanghai Children’s Medical Center affiliated to shanghai jiao tong university school of medicine,shanghai,china

BACKGROUND Over the past 60 years,the secondary sex ratio in the U.S,particularly in White women,experienced a slight but obvious *** research suggests that maternal exposure to acute stress may cause a decline of sex ratio at ***,the studies concerned the effect of maternal chronic stress on sex ratio is both limited and inconsistent. METHODS The *** live birth and infant death dataset and fetal death dataset(1995 - 2004)

关键词：