检索结果-南通市图书馆

Induction of murine interleukin-1 beta expression by water-soluble components from Hericium erinaceum

Acta Pharmacologica Sinica 2006年第8期27卷 1058-1064页

作者： Chang-gue SON~2 Jang-woo SHIN~2 Jung-hyo CHO~2 Chong-kwan CHO~2 Cheol-heui YUN~3 Seung-hyun HAN~(4,5,6) ~2East-West Cancer Center,Dunsan Oriental Hospital of Daejon university,Daejon,301-724,Republic of korea ~3school of agricultural biotechnology,seoul national university,seoul 151-742,korea ~4Department of Oromaxillofacial Infection and Immunity and Dental Research Institute,school of Dentistry,seoul national university.seoul 110-749,korea ~5Laboratory Sciences Division,International Vaccine Institute.seoul 151-818.korea East-West Cancer Center Dunsan Oriental Hospital of Daejon University Daejon Republic of Korea school of agricultural biotechnology Seoul National University Seoul Korea Department of Oromaxillofacial Infection and Immunity and Dental Research Institute School of Dentistry Seoul National University Seoul Korea Laboratory Sciences Division International Vaccine Institute Seoul Korea

Aim:To investigate the inductive effect of water extract from Hericium erinaceum(WEHE)on interleukin-1β(IL-1β)***:A murine macrophagecell-line,RAW 264.7 was stimulated with 1 to 10 mg/L WEHE and inductions of IL-1β protein and its steady state mRNA were examined using a bioassay,Westernblotting,and reverse transcription-polymerase chain reaction(RT-PCR)*** inductive effect of WEHE on IL-1β gene expression was further investigatedby a chloramphenicol acetyltransferase(CAT)reporter gene assay using a tran-sient transfection with pIL-1(870 bp)-CAT where the expression of the CAT genewas regulated by a IL-1β *** electrophoretic mobility shift assay(EMSA)was also performed to examine transcription factors,nuclear factor-kappa B(NF-kB),activator protein 1(AP-1),nuclear factor interleukin-6(NF-IL6),and cAMPresponse element(CRE)/activating transcription factor(ATF).Results:WEHEinduced IL-1β production in both its mRNA and protein expression in a dose-dependent *** inductive effect of WEHE on IL-1β gene expression wasdue to the augmentation of the IL- 1β ***,EMSA showedthat WEHE markedly increased the binding activities of NF-kB,and to a lesserextent,those of AP-1 and NF-IL6 to their cognate DNA recognition sites,whereasCRE/ATF binding remained constant,all of which are known to be involved in theregulation of IL-1β gene ***:WEHE induces IL-1β expres-sion in macrophages at a transcriptional level by enhancing the activation oftranscription factors,NF-kB,NF-IL6,and AP-1.

关键词： Hericium erinaceum interleukin-1 lipopolysaccharide

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cause and consequence of landscape fragmentation and changing disturbance by socio-economic development in mountain landscape system of South korea

引用

Journal of Environmental Sciences 1999年第2期11卷 54-60页

作者： Sun Kee Hong Center for Education Research, seoul national university, seoul 151 742, korea

Through the statistics and the analysis of landscape map, changes of lands use regime and landscape structure during 20 years were investigated in the agriculture forestry complexed mountain landscape system of Yangdong Myon, Yangpyung Gun in the central korea. Landscape changes of this region was inter related to the recent socio economic development of rural life. Utilization of biomass and other traditional forest management were drastically abandoned in recent 10 years. Landscape analysis of maps showed that the area of secondary vegetation that had been sustained by human nature disturbance was decreased by using of plantation during this time. Those decreased areas were replaced to plantation for wood production and other purpose. Past area of woody species dominated in plantation also substituted to other species. Traditional human activity on secondary vegetation was disappeared. Consequently, the advanced management regimes such as new plantation and cultivation extending areas were increased in abandoned land.

关键词： human disturbance korea mountain landscape landscape fragmentation urbanization.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CO_2 exchange at air-sea interface in the Huanghai Sea

引用

Acta Oceanologica Sinica 2000年第1期19卷 79-89页

作者： Dong-Chan Oh Mi-Kyung Park Kyung-Ryul Kim (1. Department of Oceanography, seoul national university, seoul 151-742, korea) Department of Oceanography Seoul National University Seoul 151-742 South Korea

During the Huanghai Sea Circulation and Material Flux Expedition in Spring 1996, fco_2 in surface water and atmosphere was measured. The fco2 in surface water varied in a range from 220 to 360 uatm1) while atmospheric concentration was nearly constant at 360μatm, showing that the Huanghai Sea surface waters were undersaturated with respect to atmospheric Co during the time of investigation. A model was developed in this study in order to estimate the Co flux at the air-sea interface. The model incorporates the time-series variations of the distributions in SST (sea surface temperature), salinity, mixed-layer depth, atmospheric fco2, gas-transfer velocity, and CZCS chlorophyll concentration in the Huanghai Sea and was calibrated with the observed fco2 data. The primary parameter affecting fco2 in surface water is the variation of SST through time. The annual fluxes of Co are estimated as 0. 033 Gt C from the sea into the atmosphere and 0. 044 Gt C from the air into sea. The Huanghai Sea, thus behaves as a CO2 sink absorbing 0. 011 Gi C of CO2 a year. *** to about 0. 5 % of global oceanic absorption capacity.

关键词： Huanghai Sea CO2 exchange air-sea interface

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Millimeter-Wave Radio Telescope Project at seoul national university

引用

天文研究与技术 1999年第S1期 51-52页

作者： Koo Bon Chul (Department of Astronomy,seoul national university)

The Department of Astronomy at seoul national university is carrying out a project to build a radio observatory, the seoul Radio Astronomical Observatory (SRAO). The observatory will be constructed on our campus, which is located at sea level in seoul, korea, at (126°57.′3E, 37°27.′1N). The observatory will operate a 6 m millimeter radio telescope.

关键词： A Millimeter-Wave Radio Telescope Project at seoul national university Radio Wave

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

悖论的现代性与对新公有制社会选择的探求

引用

吉林大学社会科学学报 2005年第6期45卷 57-64页

作者：韩相震国立汉城大学社会学学科

悖论的现代性主要体现在民族国家、工人运动、官僚管理、科技、代议制民主、家庭、社会关系、功能差异性以及个人主义等都受到了严重的挑战和质疑。为了在东方传统与西方现代性之间构建起一种平衡,解决现代性所产生的问题,应走参与型公... 详细信息

悖论的现代性主要体现在民族国家、工人运动、官僚管理、科技、代议制民主、家庭、社会关系、功能差异性以及个人主义等都受到了严重的挑战和质疑。为了在东方传统与西方现代性之间构建起一种平衡,解决现代性所产生的问题,应走参与型公有制社会的道路,它既不以市场也不以国家为中心,而是以市民社会和参与运动为中心的独特的“新公有制社会”。新公有制社会的文化基础包括:涉及参与型社会力量的代理团体,涉及交流技术领域的互联网发展以及涉及社会规范的后传统再检验。在韩国,这些社会文化基础正在形成。

关键词：悖论的现代性新公有制社会市民社会公有制社会现代性社会选择悖论社会文化基础探求民族国家

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Toxicity and Carcinogenicity of Ozone in Combination with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and Dibutyl Phthalate in B6C3F1 Mice for 16 and 32 Weeks

引用

Biomedical and Environmental Sciences 2009年第3期22卷 216-222页

作者： MIN YOUNG KIM M YUNG CHO Laboratory of Toxicology College of Veterinary MedicineSeoul National University Biological Engineering Department Massachusetts Institute of Technology

Objective To evaluate the toxic and carcinogenic potential of ozone alone or in combination with 4-（N-methyl-N-nitrosamino）-1-（3-pyridyl）-1-butanone （NNK） and/or dibutyl phthalate （DBP）. Methods Male and female B6C3F1 mice were exposed, through inhalation, intravenous administration and diet, to 0.5 ppm of ozone, 1.0 mg/kg of NNK and 5000 ppm of DBP, individually and in combination for 16 and 32 weeks. Results No treatment-related death was seen, but significant differences in body and organ weights between control and treated mice were observed during the study. No incidence of lung tumor incidence was recorded in mice exposed to either ozone alone or combined treatment. Oviductal carcinomas were observed in female mice exposed to ozone or DBP alone for 16 weeks and ozone in combination with NNK and DBP for 32 weeks. Conclusion Although ozone alone and in conjunction with NNK and/or DBP does not induce lung cancer under our experimental conditions, they induce oviductal carcinomas in B6C3F1 mice.

关键词： Ozone NNK DBP Combined treatment Toxicity Carcinogenicity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

New Aspects of Extragalactic Globular Clusters

引用

天文研究与技术 1999年第S1期 159-165页

作者： Myung Gyoon Lee (Dept.of Astronomy,seoul national university,seoul 151-742,korea,mglee@astrog.snu.ac.kr)

I present a review on the new aspects of extragalactic globular clusters revealed from recent observations with ground-based telescopes and the Hubble Space *** globular clusters are ideal targets to study with large ... 详细信息

关键词： globular clusters-galaxies general-galaxies star clusters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SOME PERMUTING TRINOMIALS OVER FINITEFIELDS

引用

Acta Mathematica Scientia 1997年第3期17卷 250-254页

作者： June Bok Lee(Dept. of Math., Yonsei university, seoul, 120-749,korea)Young Ho Park (Dept. of Math., Kangwon national university, Chuncheon, 200-701,korea) Dept. of Math. Yonsei University Seoul 120-749 Korea Dept. of Math. Kangwon National University Chuncheon 200-701 Korea

Trinomial permutation polynomials of the form xr(ax2s + bxs + c) over Fq have been studied where 3|q-1 and s = (q-1)/3. We derive some necessary and sufficient conditions for these trinomials to be permutation polynomials, and construct some examples. Moreover, we discuss the relationship between permutation trinomials of the given type over a tower of finite fields.

关键词： Math SOME PERMUTING TRINOMIALS OVER FINITEFIELDS

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Instabilities in a Self-Gravitating Magnetized Gas Disk

引用

天文研究与技术 1999年第S1期 294-298页

作者： S. M. Lee, S. S. Hong ( Department of Astronomy, seoul national university, seoul 151-742, korea )

A linear stability analysis has been performed onto a self-gravitating magnetized gas disk boundxed by external pressure. The resulting dispersion relation is fully explained by three kinds of instability: a Parker-type instability driven by self-gravity, usual Jeans gravitational instability and convection. In the direction parallel to the magnetic fields, the magnetic tension completely suppresses the convection. If the adiabatic index γ is less than a certain critical value, the perturbations trigger the Parker as well as the Jeans instability in the disk. Consequently, the growth rate curve has two maxima: one at small wavenumber due to a combination of the Parker and Jeans instabilities, and the other at somewhat larger wavenumber mostly due to the Parker instability. In the horizontal direction perpendicular to the fields, the convection makes the growth rate increase monotonically upto a limiting value as the perturbation wavenumber gets large. However, at small wavenumbers, the Jeans instability becomes effective and develops a peak in the growth rate curve. Depending on the system parameters, the maximum growth rate of the convection may or may not be higher than the peak due to the Jeans-Parker instability. Therefore, a cooperative action of the Jeans and Parker instabilities can have chances to over-ride the convection and may develop large scale structures of cylindrical shape in non-linear stage. In thick disks the cylinder is expected to align its axis perpendicular to the field, while in thin ones parallel to it.

关键词： Instabilities in a Self-Gravitating Magnetized Gas Disk

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Studies on self-esteem of penile size in young koreanmilitary men

引用

Asian Journal of Andrology 2003年第3期5卷 185-189页

作者： Hwancheol Son Hanjoo Lee Jung-Sik Huh Soo Woong Kim Jae-Seung Paick Department of Urology Seoul Municipal Boramae Hospital Seoul Korea Department of Neuropsychiatry Seoul National University College of Medicine Seoul Korea Department of Urology Cheju National University College of Medicine Jeju Korea Department of Urology Seoul National University College of Medicine Seoul 110744 Korea

Aim: To investigate the flaccid and stretched penile sizes of young korean men and their complexes or pride about their penile size. Methods: After an explanation and agreement to the purpose and methods of this study, 123 korean men in their early 20's visiting the Jinhae Military General Hospital were included in the study. The flaccid penile length, flaccid mid-shaft circumference, stretched length and pre-pubic bone fat pad depth were measured in a warm comfortable environment. The accuracy the subjects assessed their penile size was investigated by asking them to rate their penile size, as 'very small', 'small', 'normal', 'large' or 'very large'. All subjects were asked to complete the Minnesota multiphasic personality inventory (MMPI) test. Results: The mean flaccid length, flaccid circumference, stretched length and fat pad depth of the 123 subjects were (6.9 ± 0.8) cm, (8.5 ±1.1) cm, (9.6 ± 0.8) cm and (1.1 ± 0.4) cm, respectively. The answer distribution on penile size was 1 (0.8 %) 'very small', 29 (23.6 %) 'small', 86 (69.9 %) 'normal', 6 (4.9 %) 'large' and 1 (0.8 %) 'very large'. Subjects who underestimated their penile size showed significantly higher scores on the hypochondriasis (Hs), depression (D) and psychasthenia (Pt) subscales of the MMPI than those in the Unbiased Group (P<0.05). Conclusion: In consultation, with a patient requesting penile augmentation, the urologist should consider the psychologic attitude of the patient to his penile size.

关键词： penile size penile length self esteem MMPI psychology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：