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Clinical Predictors of Outcome in Patients with Anti-neutrophil Cytoplasmic Autoantibody-related Renal Vasculitis： Experiences from a Single-center

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Chinese Medical Journal 2017年第8期130卷 899-905页

作者： Lei Pu Gui-Sen Li yu-Rong zou Ping Zhang Li Wang Renal Division and Institute of Nephrology Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China School of Medicine University of Electronic Science and Technology of China Chengdu Sichuan 610072 China

Background： Primary anti-neutrophil cytoplasmic antibody-associated vasculitis （AAV） is a chronic autoimmune disease associated with multisystem dysfunction. Renal involvement is common and closely associated with outcome. The purpose of this study was to investigate the clinical determinants of mortality of patients with AAV-related renal injury in the first 2 years after diagnosis in a single West Chinese center. Methods： Demographic and laboratory parameters of 123 consecutive patients with AAV-related renal injury diagnosed in Renal Division and Institute ofNephrology, Sichuan Provincial People＇s Hospital between 2004 and 2012 were collected retrospectively. All patients were followed up for 2 years after diagnosis. Survivors were compared with nonsurvivors to identify the clinical baseline variables associated with mortality. Multivariate Cox regression model was used to determine the independent predictors of mortality. Results： Of the 123 patients, 46 （37.4%） died by the end of 2 years after diagnosis, with 41 （33.3%） patients dying within the first 12 months. In comparison with the survivors, Birmingham Vasculitis Activity Score （BVAS）, the incidence of pulmonary hemorrhage and digestive system （DS） involvement, serum creatinine, and erythrocyte sedimentation rate were significantly higher in nonsurvivors, whereas lymphocyte counts, hemoglobin, and complement 3 （C3） were significantly lower. Renal replacement therapy was more common in nonsurvivors. High BVAS （hazard ratio [HR] = 1.058, 95% confidence interval [CI]： 1.002-1. I17; P = 0.042）, pulmonary hemorrhage （MR = 1.970, 95% CI： 1.033-3.757; P = 0.04）, DS involvement （HR = 2.911,95% （7：1.212-6.911 ： P = 0.017）4 and serum creatinine 〉400 μmol/L （MR = 2.910, 95% CI： 1.271-6.664, P = 0.012） were independent predictors of death in patients with AAV-related renal injury. Conclusions： Patients with AAV-related renal injury have high early mortality. Those with high BVAS （particularly with pulmonary or DS invol

关键词： Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis Mortality Predictors Renal Involvement

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Knowledge Tracking Model Based on Learning Process

Knowledge Tracking Model Based on Learning Process

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作者： yu zou Xiaodong Yan Wei Li School of Information Engineering Minzu University of China National Language Resource Monitoring & Research Center Minority Languages Branch

Knowledge tracking model has been a research hotspot in the field of educational data mining for a long time. Knowledge tracking can automatically discover students’ weak knowledge points, which helps to improve students’ self-motivation in learning and realize personalized guidance. The existing KT model has some shortcomings, such as the limitation of the calculation of knowledge growth, and the imperfect forgetting mechanism of the model. To this end, we proposed a new knowledge tracking model based on learning process（LPKT）, LPKT applies the idea of Memory Augmented Neural Network（MANN）.When we model the learning process of students, two additional important factors are considered. One is to consider the current state of knowledge of the students when updating the dynamic matrix of the neural network, and the other is to improve the forgetting mechanism of the model. In this paper we verified the effectiveness and superiority of LPKT through comparative experiments, and proved that the model can improve the effect of knowledge tracking and make the process of deep knowledge tracking easier to understand.

关键词： Knowledge Tracking Deep Learning Memory Augmented Neural Network

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Management with the insufficient proximal landing zone for endovascular repair in aortic dissection

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Chinese Medical Journal 2011年第19期124卷 3003-3007页

作者： MA Hao YANG Hong-yu zou Jun-jie ZHANG Xi-wei Department of General Surgery the First Affiliated HospitalNanjing Medical University Department of General Surgery Jiangsu Province Hospital Nanjing Jiangsu 210029 China

Background Sufficient length of the proximal landing zone （PLZ） is the key for a successful thoracic endovascular aortic repair （TEVAR） of an aortic lesion. The aim of this research was to investigate the safety, feasibility, efficacy, and problems of endovascular repair for aortic dissection with insufficient *** The clinical data between August 2005 and February 2010 from patients with insufficient PLZ for endovascular repair of aortic dissection were retrospectively reviewed. According to the classification proposed by Ishimaru, aortic zone 0 was involved in 3 cases, zone 1 in 10 cases, and zone 2 in 11 cases. A hybrid surgical procedure of supraortic debranching and revascularization, directly coverage the orifice of left subclavian artery, or a left common carotid artery chimney graft technique were performed to obtain an adequate proximal aortic landing *** There was no significant difference in risk factors and diameter of the PLZ between Zone 0, Zone 1, and Zone 2. But the length of the PLZ was significantly different in the three groups （P 〈0.01）. There was no significant difference in technical and clinical success rate between the *** The procedure for extending an insufficient PLZ for endovascular repair for aortic arch pathology is feasible and relatively safe. The applicability of TEVAR in such aortic disorders may be expanded.

关键词： endovascular procedures aortic dissection proximal landing zone aorta, thoracic

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论我国体育保险经纪人市场的培育与发展

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体育与科学 2006年第5期27卷 27-30页

作者：邹瑜宜春学院体育学院宜春336000

体育保险经纪人是体育保险市场发展到一定阶段的产物。我国目前已成立了体育保险经纪公司,但体育保险市场经纪人的生存空间有限,制约着体育保险经纪人作用的发挥和体育保险经纪人市场的培育和发展,面对入世承诺的逐步兑现和2008年北京... 详细信息

体育保险经纪人是体育保险市场发展到一定阶段的产物。我国目前已成立了体育保险经纪公司,但体育保险市场经纪人的生存空间有限,制约着体育保险经纪人作用的发挥和体育保险经纪人市场的培育和发展,面对入世承诺的逐步兑现和2008年北京奥运会比赛的临近,加快我国体育保险经纪人市场的培育与发展具有十分重要的意义,文章在分析体育保险经纪人的概念与业务范围的基础上,找出了我国体育保险经纪人市场目前存在的主要问题,并提出了相应的对策和建议。

关键词：体育保险市场保险经纪人

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试析唐纳兰的限定摹状词理论

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自然辩证法研究 2008年第4期24卷 35-38页

作者：邹渝西南大学逻辑智能研究所重庆400715

唐纳兰关于限定摹状词区分为归属性用法和指称性用法的观点基本合理,但他对罗素和斯特劳森的摹状词指称理论的批评有失偏颇,因为罗素主要是从语义学的角度谈论摹状词的指称,斯特劳森则首次区分了语词的指称性使用和归属性使用,指出了从... 详细信息

唐纳兰关于限定摹状词区分为归属性用法和指称性用法的观点基本合理,但他对罗素和斯特劳森的摹状词指称理论的批评有失偏颇,因为罗素主要是从语义学的角度谈论摹状词的指称,斯特劳森则首次区分了语词的指称性使用和归属性使用,指出了从语用学层面研究语词的新思路。唐纳兰关于限定摹状词的两种用法的观点,实际上是对罗素和斯特劳森观点的发展,特别是对斯特劳森的工作的进一步深化和发展。他是在罗素和斯特劳森的基础上提出了更为丰富的摹状词指称理论。

关键词：限定摹状词指称性用法归属性用法

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COLING/ACL 2006会议报道

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中文信息学报 2007年第1期21卷 127-128页

作者：邹煜中国传媒大学应用语言学系北京100024

第21届国际计算语言学学术会议和第44届计算语言学协会年会联合会议(COLING-ACL 2006)于2006年7月15～23日在悉尼成功举行,与其同期举行的还有16个卫星会议.这是两个计算语言学领域的顶级国际会议在40多年的历史中第三次联合召开,也是... 详细信息

第21届国际计算语言学学术会议和第44届计算语言学协会年会联合会议(COLING-ACL 2006)于2006年7月15～23日在悉尼成功举行,与其同期举行的还有16个卫星会议.这是两个计算语言学领域的顶级国际会议在40多年的历史中第三次联合召开,也是这类会议首次在南半球召开.

关键词：会议报道计算语言学国际会议学术会议南半球

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3DPhenoFish:Application for two-and three-dimensional fish morphological phenotype extraction from point cloud analysis

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Zoological Research 2021年第4期42卷 492-501页

作者： yu-Hang Liao Chao-Wei Zhou Wei-Zhen Liu Jing-Yi Jin Dong-Ye Li Fei Liu Ding-Ding Fan yu zou Zen-Bo Mu Jian Shen Chun-Na Liu Shi-Jun Xiao Xiao-Hui yuan Hai-Ping Liu Department of Computer Science Wuhan University of TechnologyWuhanHubei 430070China Institute of Fisheries Science Tibet Academy of Agricultural and Animal Husbandry SciencesLhasaTibet 850000China Key Laboratory of Freshwater Fish Reproduction and Development(Ministry of Education) College of FisheriesSouthwest UniversityChongqing 402460China Jiaxing Key Laboratory for New Germplasm Breeding of Economic Mycology JiaxingZhejiang 314000China Huadian Tibet Energy Co. LtdLhasaTibet 851415China China Institute of Water Resources and Hydropower Research Beijing 100038China

Fish morphological phenotypes are important resources in artificial breeding,functional gene mapping,and population-based studies in aquaculture and *** morphological measurement of phenotypes is rather expensive in terms of time and *** importantly,manual measurement is highly dependent on operational experience,which can lead to subjective phenotyping ***,we developed 3DPhenoFish software to extract fish morphological phenotypes from three-dimensional(3D)point cloud *** for background elimination,coordinate normalization,image segmentation,key point recognition,and phenotype extraction were developed and integrated into an intuitive user ***,18 key points and traditional 2D morphological traits,along with 3D phenotypes,including area and volume,can be automatically obtained in a visualized *** fine-tuning of key points and customized definitions of phenotypes are also allowed in the *** 3DPhenoFish,we performed high-throughput phenotyping for four endemic Schizothoracinae species,including Schizopygopsis younghusbandi,Oxygymnocypris stewartii,Ptychobarbus dipogon,and Schizothorax *** indicated that the morphological phenotypes from 3DPhenoFish exhibited high linear correlation(>0.94)with manual measurements and offered informative traits to discriminate samples of different species and even for different populations of the same *** summary,we developed an efficient,accurate,and customizable tool,3DPhenoFish,to extract morphological phenotypes from point cloud data,which should help overcome traditional challenges in manual measurements.3DPhenoFish can be used for research on morphological phenotypes in fish,including functional gene mapping,artificial selection,and conservation studies.3DPhenoFish is an open-source software and can be downloaded for free at https://***/lyh24k/3DPhenoFish/tree/master.

关键词： Fish Phenomics Morphology Point cloud 3D scanning

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玻璃钢管道相贯线机器人铣削轨迹规划

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中国机械工程 2018年第24期29卷 2980-2987页

作者：尤波邹宇许家忠哈尔滨理工大学自动化学院哈尔滨150080

针对目前玻璃钢管相贯线开孔工艺中存在的管道型号繁多、手工不易加工以及普通铣削机床适应性较差等问题,利用机器人的高度灵活性、适用范围广和自动化程度高等柔性特征,研究了机器人铣削玻璃钢管道相贯线的轨迹规划。迹建立了管道相贯... 详细信息

针对目前玻璃钢管相贯线开孔工艺中存在的管道型号繁多、手工不易加工以及普通铣削机床适应性较差等问题,利用机器人的高度灵活性、适用范围广和自动化程度高等柔性特征,研究了机器人铣削玻璃钢管道相贯线的轨迹规划。迹建立了管道相贯线的坡口模型,计算出每个轨迹点的铣削厚度;基于机器人逆运动学,对机器人的空间连续运动轨迹进行了规划;设计了机器人铣削工作站运行该轨迹;最后对工作站的铣削性能进行了实验验证。实验结果表明,坡口表面光滑平整,该机器人工作站连续性好,自动化程度高,能够很好地完成玻璃钢管相贯线的铣削工作。

关键词：玻璃钢管道相贯线铣削机器人坡口模型

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伏特效应放射性同位素电池的原理和进展

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核技术 2006年第6期29卷 432-437页

作者：邹宇黄宁康辐射物理及技术教育部重点实验室四川大学原子核技术研究所成都610064

本文介绍伏特效应放射性同位素电池的工作原理及电池类型。重点介绍了适用于心脏起搏器、微机电系统(MEMs)等的辐射伏特效应放射性同位素微电池,并对这种电池的应用前景作了展望。

关键词：衰变能放射性同位素电池伏特效应

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Hydrogel-exosome system in tissue engineering:A promising therapeutic strategy

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Bioactive Materials 2024年第8期38卷 1-30页

作者： Ming-Hui Fan Jin-Kui Pi Chen-yu zou Yan-Lin Jiang Qian-Jin Li Xiu-Zhen Zhang Fei Xing Rong Nie Chen Han Hui-Qi Xie Department of Orthopedic Surgery and Orthopedic Research Institute Laboratory of Stem Cell and Tissue EngineeringState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduSichuan610041PR China Core Facilities West China HospitalSichuan UniversityChengduSichuan610041PR China Frontier Medical Center Tianfu Jincheng LaboratoryChengduSichuan610212PR China

Characterized by their pivotal roles in cell-to-cell communication,cell proliferation,and immune regulation during tissue repair,exosomes have emerged as a promising avenue for“cell-free therapy”in clinical ***,possessing commendable biocompatibility,degradability,adjustability,and physical properties akin to biological tissues,have also found extensive utility in tissue engineering and regenerative *** synergistic combination of exosomes and hydrogels holds the potential not only to enhance the efficiency of exosomes but also to collaboratively advance the tissue repair *** review has summarized the advancements made over the past decade in the research of hydrogel-exosome systems for regenerating various tissues including skin,bone,cartilage,nerves and tendons,with a focus on the methods for encapsulating and releasing exosomes within the *** has also critically examined the gaps and limitations in current research,whilst proposed future directions and potential applications of this innovative approach.

关键词： Exosome Hydrogel Tissue engineering Regenerative medicine

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