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Timing theory continuous nursing,resistance training:Rehabilitation and mental health of caregivers and stroke patients with traumatic fractures

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World Journal of Clinical Cases 2022年第5期10卷 1508-1516页

作者： Ya-Li Shen zong-qun zhang Li-Juan Zhu Jing-Hua Liu Department of Orthopedics Chengde Central HospitalChengde 067000Hebei ProvinceChina Department of Neurology Chengde Central HospitalChengde 067000Hebei ProvinceChina Department of Nursing Chengde Central HospitalChengde 067000Hebei ProvinceChina

BACKGROUND Stroke is the leading cause of adult lifelong disability worldwide.A stroke is an acute cerebrovascular disease with a variety of causes and corresponding clinical *** 75%of surviving stroke patients experience impaired nerve function,and some suffer from traumatic fractures,which can lead to special care *** To determine the effect of timing theory continuous care,with resistance training,on the rehabilitation and mental health of caregivers and stroke patients with traumatic *** Between January 2017 to March 2021,we selected 100 hospital admissions with post-stroke hemiplegia complicated with a traumatic *** participant groups were created:(1)Control group:given resistance training;and(2)Observation group:given timing theory continuous care combined with resistance *** degree of satisfaction and differences in bone and phosphorus metabolism indexes between the two groups were *** self-perceived burden scale(SPBS)and caregiver burden questionnaire were used to evaluate the psychological health of patients and *** Harris hip function score,ability of daily living(ADL)scale,and global quality of life questionnaire(GQOL-74)were used to evaluate hip function,ability of daily living,and quality of *** Data were collected prior to and after *** phosphatase(ALP),osteocalcin,and vitamin D3 in the observation group and control group increased after intervention(P0.05).The SPBS score of the observation group was lower and the ADL score was higher than the control *** burden score was lower and the Harris hip function and GQOL-74 scores were higher than that of the control group(P<0.05).The observa

关键词： Timing theory continuous nursing Resistance training Stroke Traumatic fracture Mental health

Protective Effects of Phellodendron Species on Bone Health: A Novel Perspective on Their Potentials in Treating Osteoporosis and Osteoarthritis

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Chinese Journal of Integrative Medicine 2024年第4期30卷 379-384页

作者： XIN Li TAN Guo-yao zhang Qiang zhang qun Good Clinical Practice Development Guangdong Provincial Key Laboratory of Bone and Joint Degeneration DiseasesThe Third Affiliated Hospital of Southern Medical UniversityGuangzhou(510630)China Department of Pharmacy Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou(510120)China

Phellodendron(PN)species,traditionally used in Chinese medicine for centuries,hold promise as a potential treatment for osteoporosis(OP)and osteoarthritis(OA)due to their bioactive *** bioactive compounds,including berberine and palmatine,exhibit anti-inflammatory,antioxidant,and bone-protective properties,contributing to their potential therapeutic benefits in promoting bone health and preventing bone ***,challenges such as the need for standardized preparation and dosing,limited clinical studies,and potential interactions with other medications hinder their clinical ***,the rich history of PN species in Chinese medicine provides a promising foundation for future investigation into their potential as alternative treatments for OP and *** research is needed to fully understand the underlying mechanisms of action and explore the clinical implications of PN for bone health.

关键词： Phellodendron species bone health osteoporosis osteoarthritis review

Prediction of the thermal conductivity of Mg–Al–La alloys by CALPHAD method

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International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 129-137页

作者： Hongxia Li Wenjun Xu Yufei zhang Shenglan Yang Lijun zhang Bin Liu qun Luo Qian Li State Key Laboratory of Advanced Special Steels&Shanghai Key Laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai UniversityShanghai 200444China National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China National Key Laboratory of Advanced Casting Technologies Chongqing UniversityChongqing 400044China

Mg-Al alloys have excellent strength and ductility but relatively low thermal conductivity due to Al *** accurate prediction of thermal conductivity is a prerequisite for designing Mg-Al alloys with high thermal ***,databases for predicting temperature-and composition-dependent thermal conductivities must be *** this study,Mg-Al-La alloys with different contents of Al2La,Al3La,and Al11La3phases and solid solubility of Al in the α-Mg phase were *** influence of the second phase(s) and Al solid solubility on thermal conductivity was *** results revealed a second phase transformation from Al_(2)La to Al_(3)La and further to Al_(11)La_(3)with the increasing Al content at a constant La *** degree of the negative effect of the second phase(s) on thermal diffusivity followed the sequence of Al2La>Al3La>Al_(11)La_(3).Compared with the second phase,an increase in the solid solubility of Al in α-Mg remarkably reduced the thermal *** the basis of the experimental data,a database of the reciprocal thermal diffusivity of the Mg-Al-La system was established by calculation of the phase diagram (CALPHAD)*** a standard error of±1.2 W/(m·K),the predicted results were in good agreement with the experimental *** established database can be used to design Mg-Al alloys with high thermal conductivity and provide valuable guidance for expanding their application prospects.

关键词： magnesium alloy thermal conductivity thermodynamic calculations materials computation

SCREEN:predicting single-cell gene expression perturbation responses via optimal transport

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Frontiers of Computer Science 2024年第3期18卷 255-257页

作者： Haixin WANG Yunhan WANG qun JIANG Yan zhang Shengquan CHEN Cadre Medical Department The 1st Clinical CenterChinese PLA General HospitalBeijing 100853China School of Statistics Renmin University of ChinaBeijing 100872China Ministry of Education Key Laboratory of Bioinformatics Bioinformatics Division of BNRISTDepartment of AutomationTsinghua UniversityBeijing 100084China School of Mathematical Sciences and LPMC Nankai UniversityTianjin 300071China

1 Introduction Recent advances in single-cell RNA sequencing(scRNA-seq)have enabled the study of how individual cells respond to various external perturbations such as drug stimulation at gene expression level[1].Precisely inferring perturbation responses allows us to explore how and why individual tumor cells evade cancer treatment,greatly advancing personalized medicine research and deepening our understanding of biological mechanisms[2].However,considering the high costs of sequencing and the complexity of obtaining perturbed samples,utilizing computational methods to predict cellular responses to perturbations holds great potential[2].

关键词： stimulation perturbation deepening

Description of martensitic transformation kinetics in Fe-C-X(X = Ni,Cr,Mn,Si) system by a modified model

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1026-1036页

作者： Xiyuan Geng Hongcan Chen Jingjing Wang Yu zhang qun Luo Qian Li State Key Laboratory of Advanced Special Steels&Shanghai Key Laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Ansteel Beijing Research Institute Co. LtdBeijing 102211China National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China National Key Laboratory of Advanced Casting Technologies Chongqing UniversityChongqing 400044China

Controlling the content of athermal martensite and retained austenite is important to improving the mechanical properties of high-strength steels,but a mechanism for the accurate description of martensitic transformation during the cooling process must be *** present,frequently used semi-empirical kinetics models suffer from huge errors at the beginning of transformation,and most of them fail to exhibit the sigmoidal shape characteristic of transformation *** describe the martensitic transformation process accurately,based on the Magee model,we introduced the changes in the nucleation activation energy of martensite with temperature,which led to the varying nucleation rates of this model during martensitic *** to the calculation results,the relative error of the modified model for the martensitic transformation kinetics curves of Fe-C-X(X = Ni,Cr,Mn,Si) alloys reached 9.5% compared with those measured via the thermal expansion *** relative error was approximately reduced by two-thirds compared with that of the Magee *** incorporation of nucleation activation energy into the kinetics model contributes to the improvement of its precision.

关键词： Fe-C-X system martensitic transformation kinetics curve semi-empirical model nucleation activation energy

Centroid Hom-associative Algebras and Centroid Hom-Lie Algebras

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Acta Mathematica Sinica,English Series 2024年第4期40卷 935-961页

作者： Yu Xiu BAI Leonid A.BOKUT Yu qun CHEN Ze Rui zhang Department of Mathematics Teaching Guangzhou Civil Aviation CollegeGuangzhou 510403P.R.China Sobolev Institute of Mathematics Novosibirsk 630090Russia Novosibirsk State University Novosibirsk 630090Russia School of Mathematical Sciences South China Normal UniversityGuangzhou 510631P.R.China

In this article,we construct free centroid hom-associative algebras and free centroid hom-Lie *** also construct some other relatively free centroid hom-associative algebras by applying the Gr?bner-Shirshov basis theory for(unital)centroid hom-associative ***,we prove that the"Poincaré-Birkhoff-Witt theorem"holds for certain type of centroid hom-Lie algebras over a field of characteristic 0,namely,every centroid hom-Lie algebra such that the eigenvectors of the mapβlinearly generates the whole algebra can be embedded into its universal enveloping centroid hom-associative algebra,and the linear basis of the universal enveloping algebra does not depend on the multiplication table of the centroid hom-Lie algebra under consideration.

关键词： Centroid hom-Lie algebra centroid hom-associative algebra Gr?bner-Shirshov basis

Combined Effect of Temperature and Cadmium on Molecular Responses of Hsp70 and P-gp Genes in Crassostrea gigas

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Journal of Ocean University of China 2024年第4期23卷 1115-1120页

作者： HU Fanguang SUN Ming LIU Guangbin JING Yuanyuan CHEN qun zhang Tianwen Marine Science Research Institute of Shandong Province Qingdao 266104China

To evaluate the combined effect of temperature and cadmium on the molecular responses of heat shock protein 70(hsp70)and P-glycoprotein(P-gp)in mantle,digestive gland and gills of Crassostrea gigas,oysters were exposed to combinations of five temperature levels(10,15,20,25,and 30℃)and 10μg L^(-1)cadmium for 21 *** were sampled for mRNA quantification by qPCR,and the results showed that the P-gp gene expression changed significantly after treatment at different temperatures and different treatment *** P-gp gene expression was the highest in the digestive *** with the control group,the P-gp gene expression in cadmium treatment groups at all the different temperatures were significantly higher than the control *** control oysters(kept at 10℃during the whole experiment without cadmium)expressed low levels of hsp70,but the groups treated with cadmium displayed somewhat higher *** present study demonstrated hsp70 and P-gp played an important role in the detoxification of Cd in ***,and confirmed temperature should be considered for the assessment of Cd-induced toxicity in oysters.

关键词： temperature cadmium P-gp hsp70 Crassostrea gigas

Wheat FHB resistance assessment using hyperspectral feature band image fusion and deep learning

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 240-249页

作者： Kun Liang Zhizhou Ren Jinpeng Song Rui Yuan qun zhang College of Artificial Intelligence Nanjing Agricultural UniversityNanjing 210031China Jiangsu Province Engineering Lab for Modern Facility Agriculture Technology&Equipment Nanjing 210031China

The breeding and selection of resistant varieties is an effective way to minimize wheat Fusarium head blight(FHB)hazards,so it is important to identify and evaluate resistant *** traditional resistance phenotype identification is still largely dependent on time-consuming manual *** this paper,the method for evaluating FHB resistance in wheat ears was optimized based on the fusion feature wavelength images of the hyperspectral imaging system and the Faster R-CNN *** spectral data from 400-1000 nm were preprocessed by the multiple scattering correction(MSC)*** feature wavelengths(553 nm,682 nm and 714 nm)were selected by analyzing the X-loading weights(XLW)according to the absolute value of the peaks and troughs in different principal component(PC)load coefficient ***,the different fusion methods of the three feature wavelengths were explored with different weight *** R-CNN was trained on the fusion and RGB datasets with VGG16,AlexNet,ZFNet,and ResNet-50 networks ***,the other detection models SSD,YOLOv5,YOLOv7,CenterNet,and RetinaNet were used to compare with the Faster R-CNN *** a result,the Faster R-CNN with VGG16 was best with the mAP(mean Average Precision)ranged from 97.7%to 98.8%.The model showed the best performance for the Fusion Image-1 ***,the Faster R-CNN model with VGG16 achieved an average detection accuracy of 99.00%,which was 23.89%,1.21%,0.75%,0.62%,and 8.46%higher than SSD,YOLOv5,YOLOv7,CenterNet,and RetinaNet ***,it was demonstrated that the Faster R-CNN model based on the hyperspectral feature image fusion dataset proposed in this paper was feasible for rapid evaluation of wheat FHB *** study provided an important detection method for ensuring wheat food security.

关键词： Fusarium head blight resistance evaluation hyperspectral feature band image fusion deep learning Faster R-CNN

Re-evaluating the nano-sized inorganic protective layer on Cu current collector for anode free lithium metal batteries

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Chinese Chemical Letters 2024年第7期35卷 452-455页

作者： Shuo zhang Haitao Liao Zhi-qun Liu Chong Yan Jia-Qi Huang School of Materials Science&Engineering Beijing Institute of TechnologyBeijing 100081China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China Wuxi Yiwen Microelectronics Technology Co. Ltd.Wuxi 214000China Shanxi Research Institute for Clean Energy Tsinghua UniversityTaiyuan 030032China

Anode free lithium metal batteries(AF-LMBs)have conspicuous advantages both in energy density and the compatibility of battery manufacturing ***,the limited cycle life of AF-LMBs is a crucial factor hindering its practical *** or nitride artificial inorganic solid electrolyte interphase(SEI)has been found as an effective method to prolong the lifespan of ***,by investigating the impact of nano-sized inorganic gradient layers(LiF or Li3N)on initial Li deposition behavior,we notice that the Li^(+) diffusion barrier and the deposition morphology are highly depended on the thickness of inorganic *** protective layers cause larger overpotential as well as more aggregated Li^(+) *** study reveals that the ideal SEI should be synthesized thin and uniformly enough and uncontrollable artificial SEI can cause damage to the lifespan of AF-LMBs.

关键词： Anode free lithium metal battery Solid electrolyte interphase Nano-sized protective layer Lithium fluoride Li deposition behavior