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A role for complement blockade in kidney transplantation

Cellular & Molecular Immunology 2022年第7期19卷 755-757页

作者： Diana Karpman zivile bekassy Anne Grunenwald Lubka TRoumenina Department of Pediatrics Clinical Sciences LundLund UniversityLundSweden Centre de Recherche des Cordeliers INSERMSorbonne UniversitéUniversitéde ParisF-75006 ParisFrance

Kidney transplantation is a life-saving procedure for patients with end-stage renal failure,but unfortunately,only a limited number of patients benefit from this procedure due to organ ***,even after transplantation,the graft can be lost due to antibody-mediated rejection(AMR).A recent study by Schmitz et *** Nature Communications[1]provides new hope to prevent AMR and prolong renal allograft *** authors inhibited the innate immune complement cascade at the level of its central component C3 and successfully prevented the tissue injury mediated by donor-specific antibodies(DSAs)in a primate model.

关键词： Kidney inhibited donor

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Endothelial parameters in central and peripheral cornea in patients wearing contact lenses

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International Journal of Ophthalmology(English edition) 2018年第11期11卷 1768-1773页

作者： Saulius Galgauskas Justina Ignataviciute zivile Vieversyte Rimvydas Asoklis Vilnius University Center of eye diseases Faculty of Medicine Vilnius University

AIM： To measure the parameters of endothelium in the central and peripheral parts of the cornea and evaluate the influence of wearing the hard and soft contact lenses on the mentioned ***： A specular microscope was used to measure the corneal endothelium parameters in both eyes of 139 Caucasians（a total of 278）. All participants were divided into three groups： soft lens wearers, hard lens wearers and a control group. Factors, such as age, smoking, types of lens material, duration of lens wear and lens air permeability were assessed to determine their impact on the morphometric parameters of the ***： A lower percentage of hexagon-like cells and higher cell variation than in other groups were determined in hard contact lens wearers. The difference in density of endotheliocytes between the groups was not observed. The measurements of the morphometric parameters in soft contact lens wearers did not depend neither on the duration of lens wear, nor on air permeability. The relation between the patients＇ age and the variation of endothelium parameters was determined in the group of hard contact lens ***： Wearing hard contact lenses provokes pleomorphism and polymegethism of the corneal endothelium, while soft contact lenses do not impact any parameters of the endothelium, most likely due to higher air permeability.

关键词： corneal endothelium morphometry endothelial changes contact lenses

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TYPES OF TISSUES IN THE EXOSKELETON OF THE EARLY SILURIAN VERTEBRATES FROM TUVA AND SOUTH SIBERIA

TYPES OF TISSUES IN THE EXOSKELETON OF THE EARLY SILURIAN VE...

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第二届国际古生物学大会

作者： Valentina KARATAJUTE-TALIMAA Moya Meredith SMITH zivile ZIGAITE Institute of Geology and Geography T. Sevcenkos 13 Vilnius Lithuania Dental Institute KCL-Craniofacial Development Floor 27 Guy’s Tower London SE1 9RT UK Department of Geology and Mineralogy Vilnius University M.K.Ciurlionio 21/27 Vilnius Lithuania.University of Sciences and Technology of Lille Laboratory of Palaeozoic Palaeontology and Palaeogeography CNRS UMR 8014 F-59655 Villeneuve d’Ascq cedex France

Early vertebrates are common in Lower Silurian (Llandovery & Wenlock) of Tuva and South Siberia. The microremains appear in wide range of facies of Siberian Platform, including bar belt, restricted shallow shelf, brasckish lagoon and coastal belt facies (Karatajute-Talimaa & Predtechenskyj, 1995) as well as in shallow water facies of Tuva.

关键词： vertebrates Early Silurian hard tissues

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