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A Novel Probabilistic Saturating Counter Design for Secure Branch Predictor

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Journal of Computer Science & Technology 2021年第5期36卷 1022-1036页

作者： Lu-Tan Zhao rui Hou Kai Wang Yu-Lan Su Pei-Nan Li Dan meng State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences Beijing 100093China School of Cyber Security University of Chinese Academy of SciencesBeijing 100093China Department of Computer Science and Technology Harbin Institute of TechnologyHarbin 150001China

In a modern processor,branch prediction is crucial in effectively exploiting the instruction-level parallelism for high-performance ***,recently exposed vulnerabilities reveal the urgency to improve the security of branch *** vital cause of the branch predictor vulnerabilities is that the update strategy of the saturating counter is *** a fundamental building block in a modern branch predictor,previous studies have paid too much attention to the performance and hardware cost and ignored the security of saturating *** leaves attackers with the opportunities to perform side-channel attacks on the branch *** paper focuses on the saturating counter to explore a secure and lightweight design to mitigate branch predictor side-channel *** of applying the isolation mechanism to branch predictor resources,we propose a novel probabilistic saturating counter design to confuse the attacker's perception of the victim's *** changes the conventional deterministic state transition function to a probabilistic state transition *** a branch is committed,the conventional saturating counter needs to be updated about whether the prediction results are correct or *** for the probabilistic saturating counter,the branch predictor determines whether the update is performed based on the update *** probabilistic saturating counter dramatically reduces the ability of the attacker to spy the saturating counter's *** analyses using a cycle-accurate simulator suggest that the proposed mechanism incurs 2.4%performance overhead and hardware cost while providing strong protection.

关键词： branch predictor side-channel attack saturating counter

An Experimental Study on the Gait Patterns and Kinematics of Chinese Mitten Crabs

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Journal of Bionic Engineering 2013年第3期10卷 305-315页

作者： Jianqiao Li Xiaodong Zhang meng Zou rui Zhang Benard Chirende ruiyang Shi Cangang Wei Key Laboratory of Bionic Engineering (Ministry of Education China) Jilin University Changehun 130022 P. R. China Agricultural Research Council Institute for Agricultural Engineering Private Bag X 519 Silverton 0127 Pretoria South Africa

Despite the many studies on eight-legged animals and the importance of their mechanics of terrestrial locomotion, the mechanical energy of crabs in voluntary locomotion on uneven, unpredictable terrain surfaces has received little attention thus far. In this paper, motion video images of Chinese mitten crab （Eriocheir sinensis Milne-Edwards） locomotion on five types of terrains were recorded using a high-speed three-dimensional （3D） recording video system. The typical variables of locomotion such as gait patterns, duty factor, mechanical energy of the mass center, mass-specific write of the total mechanical power of the mass center, and percentage recovery, were analyzed. Results show that the Chinese mitten crab uses random gaits instead of the alternating tetrapod gait with the increasing terrain roughness. The duty factors of the rows of the leading legs are greater for all terrains than those of the rows of the trailing legs. On smooth terrain, the duty factors of the rows of the trailing legs are greater than that on rough terrains. Kinematic measurements and calculations reveal that similar to mammals, birds, and arthropods, the Chinese mitten crab uses two fundamental gaits to save mechanical energy： the inverted pendulum gait and the bouncing gait. The bouncing gait is the main pattern of mechanical energy conservation. The low probability of injury and energy expenditure due to adaptations to various terrains induce the Chinese mitten crab to modify the mass-specific rate of the total mechanical power of the mass center. The statistical results of percentage recovery also reveal that the Chinese mitten crab has lower energy recovery efficiency over rough terrains compared with smooth terrains.

关键词： biomechanics Chinese mitten crab gait patterns kinematics

Role of BDNF in the taste system

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Frontiers in Biology 2014年第6期9卷 481-488页

作者： Lingbin meng Xiaolei CHEN Rongqiang YANG rui JI Department of Anatomical Sciences and Neurobiology University of Louisville School of Medicine Louisville KY 40202 USA Department of Chemistry Dartmouth College Hanover NH 03755~ USA Department of Biochemistry and Molecular biology University of Louisville School of Medicine Louisville KY 40202 USA

Neurotrophins are a family of proteins that regulate neural survival, development, function and plasticity in the central and the peripheral nervous system. There are four neurotrophins： NGF, BDNF, NT-3 and NT-4. Among them, BDNF is mostly studied in the taste system due to its high expression. Recent studies have shown BDNF play an important role in the developmental and mature taste system, by regulating survival of taste cells and geniculate ganglion neurons, and maintaining and guiding taste nerve innervations. These studies imply BDNF has great potentialities for therapeutic usage to enhance sensory regeneration following nerve injury, with aging, and in some neurodegenerative diseases.

关键词： brain-derived neurotrophic factor (BDNF) taste bud geniculate ganglion chorda tympani nerve

Hovenia acerba *** and seeds extracts ameliorate alcoholic liver injury by activating the Nrf2/HO-1 signalling pathway in LO2 cells and mice

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Food Bioscience 2023年第1期51卷 235-247页

作者： rui-fei Cheng meng-ke Sun Qi-rui Hu Zeyuan Deng Bing Zhang Hongyan Li State Key Laboratory of Food Science and Technology College of Food ScienceNanchang UniversityNanchangJiangxi330047China

Hovenia acerba Lindl.(HA)was formerly used as a treatment for alcohol *** explore the mechanism of hepatoprotective effect of HA,the chemical components of Hovenia acerba *** extract(HAPE)and Hovenia acerba *** extract(HASE)were compared by ***,the alcohol damage model of human normal hepatocytes(LO2)and male Kunming mice were used to measure their effects on alcoholic liver *** showed that HASE had 32 kinds of phenolic compounds,and the main components were caffeic acid,vitexin-2′′-O-glucoside,ferulic acid hexoside,quercetin and its glycosides;HAPE had 24 kinds of phenolic compounds,and the main components were caffeic acid,kaempferol and *** phenolic content of HASE(151.73±12.66 mg gallic acid equivalent per gram of dry weight)(mg GAE/g DW)was higher than that of HAPE(17.89±1.59 mg GAE/g DW).HASE and HAPE could increase the LO2 cell viability in the alcohol damage ***,the levels of triacylglycerol(TG),total cholesterol(TC),alanine aminotransferase(ALT),and aspartate aminotransferase(AST)were decreased,the activities of superoxide dismutase(SOD)and catalase(CAT)were increased,and the concentration of malondialdehyde(MDA)was decreased in both HASE and HAPE treated cell and mice *** also showed that the concentration of reduced glutathione(GSH)and the activity of glutathione peroxidase(GSH-Px)were increased in *** and HAPE raised the mRNA expressions of nuclear factor erythroid-2 related factor 2(Nrf2)and activated antioxidant-related genes:heme oxygenase-1(HO-1),NADPH quinone acceptor oxidoreductase 1(NQO1),and glutamate-cysteine ligase modifier subunit(GCLM),and enhanced the expression of Nrf2 and HO-1 *** and HAPE could also increase antioxidant activity by enhancing Nrf2-mediated inducible expression of HO-1 to protect hepatocytes from ***,HASE showed better liver protective effect than *** study demonstrated the protective benefits o

关键词： Hovenia acerba Lindl.peduncles extract(HAPE) Hovenia acerba Lindl.seeds extract(HASE) Alcoholic liver disease(ALD) Oxidative stress

Simulation research on online marketing strategies of branded agricultural products based on the difference in opinion leader attitudes

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Information Processing in Agriculture 2021年第4期8卷 528-536页

作者： meng-jie Liao Jian Zhang rui-mei Wang Lin Qi College of Economics and Management Beijing Information Science and Technology UniversityBeijing 100192China Laboratory of Big Data Decision Making for Green Development Beijing 100192China College of Economics and Management China Agricultural UniversityBeijing 100083China

By virtue of the low-cost and high-efficiency internet traffic monetizing ability,key opinion leaders(KOL)have achieved great success on social media platforms in terms of agricultural brand e-commerce ***,opinion leaders tend to adopt different promotion strategies according to their preference to *** to optimize online marketing strategies based on the difference in opinion leaders’attitudes remains a problem demanding prompt solution for agricultural product brand *** study takes agricultural product brand enterprises and opinion leaders with limited rationality as the research *** the premise of considering the difference in opinion leaders’attitudes towards brands,the paper combines the evolutionary game theory to construct agricultural product brands’online promotion strategy evolutionary model,adopts visualization system to simulate the evolutionary process of brand online promotion strategies,verifies model validity and explores the influencing mechanism of punishment on opinion leaders’negative *** of multi-agent-based simulation demonstrate that investment in brand promotion,irrelevant to opinion leaders’attitudes towards brands,pertains to the absolute advantage strategy of agricultural product brand *** intensity of punishment against opinion leaders following negative promotion may change opinion leaders’promotion strategies for agricultural product ***,the present study provides an idea and reference to the management decisions of agricultural product brand enterprises’online brand promotion strategies.

关键词： Agricultural product brand Opinion leader Online promotion strategy Evolutionary game Multi-Agent-Based simulation

Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis

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Military Medical Research 2021年第1期8卷 48-61页

作者： meng-meng Yang Lu Wang Yu Zhang rui Yuan Yan Zhao Jie Hu Fei-Hu Zhou Hong-Jun Kang Department of Critical Care Medicine The First Medical CentreChinese PLA General HospitalNo.28Fuxing RoadHaidian DistrictBeijing 100853China Medical School of Chinese PLA BeijingChina

Background: Heat stroke(HS) is a serious, life-threatening disease. However, there is no scoring system for HS so far. This research is to establish a scoring system that can quantitatively assess the severity of exertional heat stroke(EHS).Methods: Data were collected from a total of 170 exertional heat stroke(EHS) patients between 2005 and 2016 from 52 hospitals in China. Univariate statistical methods and comparison of the area under the receiver operating characteristic(ROC) curve(AUC) were used to screen exertional heat stroke score(EHSS) parameters, including but not limited body temperature(T), Glasgow Coma Scale(GCS) and others. By comparing the sizes of the AUCs of the APACHE II, SOFA and EHSS assessments, the effectiveness of EHSS in evaluating the prognosis of EHS patients was ***: Through screening with a series of methods, as described above, the present study determined 12 parameters – body temperature(T), GCS, p H, lactate(Lac), platelet count(PLT), prothrombin time(PT), fibrinogen(Fib), troponin I(Tn I), aspartate aminotransferase(AST), total bilirubin(TBIL), creatinine(Cr) and acute gastrointestinal injury(AGI) classification – as EHSS parameters. It is a 0–47 point system designed to reflect increasing severity of heat stroke. Low(EHSS35) showed 100% survival and 100% mortality, respectively. We found that AUCEHSS>AUCSOFA>AUCAPACHE ***: A total of 12 parameters – T, GCS, p H, Lac, PLT, PT, Fib, Tn I, AST, TBIL, Cr and gastrointestinal AGI classification – are the EHSS parameters with the best effectiveness in evaluating the prognosis of EHS patients. As EHSS score increases, the mortality rate of EHS patients gradually increases.

关键词： Exertional heat stroke Scoring system Prognosis Effectiveness of evaluation

The analysis of electrical performances of nanowires silicon solar cells

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Science China(Technological Sciences) 2011年第12期54卷 3341-3346页

作者： LI HaoFeng JIA rui DING WuChang CHEN Chen meng YanLong LIU XinYu Institute of Microelectronics Chinese Academy of Sciences Beijing 100029 China

A theoretical model of silicon solar cells with ultra-small textured surface has been established based on depletion approximation and drift diffusion theory. The ultra-small textured surface achieves the low reflectance by multiple reflections among the silicon nanowires （NWs）. The electrical performances of the solar cells, including open circuit voltage （Voc）, short circuit current （lsc） and conversion efficiency （η）, are analyzed by the theoretical model. The results show that the low reflectance is not the only pursuit in manufacturing the Si NWs solar cells. Other factors including optimizing the surface passivation, improving the silicon wafers quality and designing the proper nanowire length should be considered together with NWs structure.

关键词： ultra-small textured surface solar cell electrical properties

Analysis of Phthalate Esters in Air, Soil and Plants in Plastic Film Greenhouse

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Chinese Chemical Letters 2002年第6期13卷 557-560页

作者： Xi Kui WANG Wei Lin GUO Ping rui meng Jia An GAN College of Chemistry and Environmental Science University of JinanJinan 250022

The phthalate esters such as DMP, DEP, DBP and DEHP in air, soil and plant samples in plastic film greenhouse were clean up with fine silica gel column and determined with HPLC. It was found that the concentrations of PEs in air and soil samples in plastic film greenhouse are much higher than those of contrast samples. But concentrations of PEs in plants in plastic film greenhouse are not remarkably affected by the pollution of air and soil.

关键词： Phthalate esters plastic film greenhouse analysis.

Review on analytical technologies and applications in metabolomics

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BIOCELL 2024年第1期48卷 65-78页

作者： XIN meng YAN LIU SHUJUN XU LIANRONG YANG rui YIN School of Pharmacy Heilongjiang University of Chinese MedicineHarbinChina

Over the past decade,the swift advancement of metabolomics can be credited to significant progress in technologies such as mass spectrometry,nuclear magnetic resonance,and multivariate ***,metabolomics garners widespread application across diverse fields including drug research and development,early disease detection,toxicology,food and nutrition science,biology,prescription,and chinmedomics,among *** serves as an effective characterization technique,offering insights into physiological process alterations in *** changes may result from various exogenous factors like environmental conditions,stress,medications,as well as endogenous elements including genetic and protein-based *** potential scientific outcomes gleaned from these insights have catalyzed the formulation of innovative methods,poised to further broaden the scope of this ***,metabolomics has evolved into a valuable and widely accepted instrument in the life ***,comprehensive reviews focusing on the sample preparation and analytical methodologies employed in metabolomics within the life sciences are surprisingly *** review aims to fill that gap,providing an overview of current trends and recent advancements in *** emphasis is placed on sample preparation,sophisticated analytical techniques,and their applications in life science research.

关键词： Metabolomics Sample preparation Analytical methods Application of metabolomics