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Nonlinear dynamics of a circular curved cantilevered pipe conveying pulsating fluid based on the geometrically exact model

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 261-276页

作者： Runqing CAO zilong guo Wei CHEN Huliang DAI Lin WANG Department of Engineering Mechanics School of Aerospace EngineeringHuazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074China State Key Laboratory of Intelligent Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

Due to the novel applications of flexible pipes conveying fluid in the field of soft robotics and biomedicine,the investigations on the mechanical responses of the pipes have attracted considerable *** fluid-structure interaction(FSI)between the pipe with a curved shape and the time-varying internal fluid flow brings a great challenge to the revelation of the dynamical behaviors of flexible pipes,especially when the pipe is highly flexible and usually undergoes large *** this work,the geometrically exact model(GEM)for a curved cantilevered pipe conveying pulsating fluid is developed based on the extended Hamilton's *** stability of the curved pipe with three different subtended angles is examined with the consideration of steady fluid *** attention is concentrated on the large-deformation resonance of circular pipes conveying pulsating fluid,which is often encountered in practical *** constructing bifurcation diagrams,oscillating shapes,phase portraits,time traces,and Poincarémaps,the dynamic responses of the curved pipe under various system parameters are *** mean flow velocity of the pulsating fluid is chosen to be either subcritical or *** numerical results show that the curved pipe conveying pulsating fluid can exhibit rich dynamical behaviors,including periodic and quasi-periodic *** is also found that the preferred instability type of a cantilevered curved pipe conveying steady fluid is mainly in the flutter of the second *** a moderate value of the mass ratio,however,a third-mode flutter may occur,which is quite different from that of a straight pipe system.

关键词： curved pipe conveying fluid pulsating fluid geometrically exact model(GEM) nonlinear dynamics parametric vibration flutter

Mutation in a non-force-bearing region of protein L influences force-dependent unfolding behavior

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Chinese Physics B 2024年第7期33卷 624-629页

作者：蒋环杰王艳伟陈家媛胡丹潘海郭子龙陈虎 Department of Physics Wenzhou UniversityWenzhou 325035China Center of Biomedical Physics Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325000China Research Institute for Biomimetics and Soft Matter Fujian Provincial Key Laboratory for Soft Functional Materials ResearchDepartment of PhysicsXiamen UniversityXiamen 361005China

Single-molecule magnetic tweezers(MTs) have revealed multiple transition barriers along the unfolding pathway of several two-state proteins, such as GB1 and Csp. In this study, we utilized MTs to measure the force-dependent folding and unfolding rates of both protein L(PLWT) and its Y47W mutant(PLY47W) where the mutation point is not at the force-bearing β-strands. The measurements were conducted within a force range of 3–120 pN. Notably, the unfolding rates of both PLWT and PWY47W exhibit distinct force sensitivities below 50 pN and above 60 pN, implying a two-barrier free energy landscape. Both PLWT and PLY47W share the same force-dependent folding rate and the same transition barriers,but the unfolding rate of PLY47W is faster than that of PLWT. Our finding demonstrates that the residue outside of the force-bearing region will also affect the force-induced unfolding dynamics.

关键词： protein folding magnetic tweezers protein L

时效前预拉伸处理对TiB_(2)/7056复合材料组织与性能的影响

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中南大学学报（自然科学版） 2024年第8期55卷 3072-3082页

作者：郭子龙王邓彪陈送义蒋日鹏李昉陈庚张晨陈康华中南大学极端服役性能精准制造全国重点实验室湖南长沙410083 中南大学轻合金研究院湖南长沙410083 中南大学粉末冶金研究院湖南长沙410083

采取扫描电镜、透射电镜等显微组织表征方法并结合室温拉伸、室温摆锤冲击实验和应力腐蚀等测试手段,研究时效前预拉伸处理对TiB_(2)/7056复合材料组织与性能的影响。研究结果表明:随着时效前预拉伸量增加,TiB_(2)/7056复合材料的位错... 详细信息

采取扫描电镜、透射电镜等显微组织表征方法并结合室温拉伸、室温摆锤冲击实验和应力腐蚀等测试手段,研究时效前预拉伸处理对TiB_(2)/7056复合材料组织与性能的影响。研究结果表明:随着时效前预拉伸量增加,TiB_(2)/7056复合材料的位错密度显著增加,经时效热处理后的晶内析出相直径增大,晶界析出相形貌由链状转变为粗大不连续状,无沉淀析出带宽化;TiB_(2)/7056复合材料的强度先增大后减小,冲击韧性能与延伸率降低;与无预拉伸相比,预拉伸的TiB_(2)/7056复合材料的应力腐蚀抗力显著提升(扩展速率降低1个量级),其主要原因是不连续粗大的晶界析出相阻断了应力腐蚀裂纹的扩展。

关键词： TiB_(2)铝基复合材料 7056铝合金预拉伸显微组织应力腐蚀

REPUBLISHED TEXTS IN THE ATTIC ORATORS

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Journal of Ancient Civilizations 2021年第2期36卷 139-172,299页

作者： zilong guo IHAC NENUChangchun

In the present article,I explore the passages that are reused in the Attic orators,particularly those as transmitted in the judicial speeches by Antiphon and Demosthenes.I argue that the favorable reactions from their audiences or clients in the past legal cases are what encourage the orators to reuse,or republish,the passages,and that there is a tendency among them to make modifications to suit changing socio-political circumstances and specific performative *** conclusion is that the republished texts highlight the common practice of the logographers in Classical Athens,and thus contribute to our understanding of their habitual way of writing and method of self-promotion.

关键词： legal promotion conclusion

Dynamic analysis and regulation of the flexible pipe conveying fluid with a hard-magnetic soft segment

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Applied Mathematics and Mechanics(English Edition) 2022年第9期43卷 1415-1430页

作者： zilong guo Qiao NI Wei CHEN Huliang DAI Lin WANG Department of Mechanics Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074China State Key Lab of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of TechnologyDalian 116024Liaoning ProvinceChina

The recently developed hard-magnetic soft(HMS)materials can play a significant role in the actuation and control of medical devices,soft robots,flexible electronics,*** regulate the mechanical behaviors of the cantilevered pipe conveying fluid,the present work introduces a segment made of the HMS material located somewhere along the pipe *** on the absolute node coordinate formulation(ANCF),the governing equations of the pipe conveying fluid with an HMS segment are derived by the generalized Lagrange *** solving the derived equations with numerical methods,the static deformation,linear vibration characteristic,and nonlinear dynamic response of the pipe are *** result of the static deformation of the pipe shows that when the HMS segment is located in the middle of the pipe,the downstream portion of the pipe centerline will keep a straight shape,providing that the pipe is stable with a relatively low flow ***,it is possible to precisely regulate the ejection direction of the fluid flow by changing the magnetic and fluid *** is also found that the intensity and direction of the external magnetic field greatly affect the stability and dynamic response of the pipe with an HMS *** most cases,the magnetic actuation increases the critical flow velocity for the flutter instability of the pipe system and suppresses the vibration amplitude of the pipe.

关键词： hard-magnetic soft(HMS)material pipe conveying fluid absolute node coordinate formulation(ANCF) stability dynamic response regulation

Force-dependent unfolding and folding dynamics of protein alpha-catenin modulation domains

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Journal of Innovative Optical Health Sciences 2019年第1期12卷 22-28页

作者： Xueping Li Weili Zhai zilong guo Hu Chen Research Institute for Biomimetics and Soft Matter Fujian Provincial Key Lab for Soft Functional Materials Research Department of Physics Xiamen UniversityXiamenChina

α-catenin is an adhesion protein located at the cadherin-based cell-cell adherens junction.α-catenin cross-linksβ-catenin and actin fiber in the adhesion protein complex,and plays an important role in the formation and modulation of cell-cell *** central modulation domains can be unfolded to expose binding site of vinculin when stretching force is ***,we studied the force-induced unfolding dynamics ofα-catenin modulation domains under different loading rates from which the unfolding distance of M2 and M3 domains is determined to be 5-7 nm,and an unfolding intermediate state is *** also found that the folding process of M1-M3 domains goes through different pathways with cooperativity.

关键词： α-catenin folding and unfolding magnetic tweezer Bell's model

自然时效耦合预拉伸提升Al-Zn-Mg-Cu合金力学性能和腐蚀抗力

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金属热处理 2024年第4期49卷 104-110页

作者：董泰励李昉陈庚张晨郭子龙陈康华陈送义中南大学轻合金研究院湖南长沙410083 中南大学有色金属先进结构材料与制造协同创新中心湖南长沙410083 中南大学粉末冶金研究院湖南长沙410083

采用透射电镜(TEM)、扫描电镜(SEM)、拉伸试验、剥落腐蚀和晶间腐蚀等手段研究了不同自然时效时间耦合3%预拉伸对Al-Zn-Mg-Cu合金时效析出组织、力学和耐腐蚀性能的影响。结果表明,自然时效4天耦合3%预拉伸能调控后续时效过程中晶界附... 详细信息

采用透射电镜(TEM)、扫描电镜(SEM)、拉伸试验、剥落腐蚀和晶间腐蚀等手段研究了不同自然时效时间耦合3%预拉伸对Al-Zn-Mg-Cu合金时效析出组织、力学和耐腐蚀性能的影响。结果表明,自然时效4天耦合3%预拉伸能调控后续时效过程中晶界附近的时效析出行为,显著地减小晶界附近无析出带宽度。其原因是自然时效4天后晶界附近无析出带存在大量溶质原子,再经3%预拉伸在晶界附近无析出带产生大量位错,促进后续时效过程析出相形核,从而减小晶界附近无析出带。窄的晶界附近无析出带能避免位错的塞积,抑制孔洞长大和裂纹扩展,显著提高合金的伸长率。同时在阳极溶解过程中,减少被腐蚀的阳极暴露面积,从而降低腐蚀速率,增加剥落腐蚀和晶间腐蚀抗力。自然时效4天耦合3%预拉伸工艺获得的抗拉强度、伸长率和最大晶间腐蚀深度分别为562 MPa、17.23%和191.4μm。

关键词：形变热处理 Al-Zn-Mg-Cu合金无析出带拉伸性能耐腐蚀性能

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水稻抗倒伏候选基因的鉴定与功能分析

华中农业大学学报 2024年第2期43卷 75-84页

作者：西若曲宗向登豪郭子龙姚义龙董发明熊立仲作物遗传改良全国重点实验室武汉430070 湖北洪山实验室武汉430070 福建农林大学海峡联合研究院福州350002

为进一步挖掘控制水稻抗倒伏的基因,以524份水稻种质资源为材料,采用GWAS(genome-wide association analysis)鉴定与抗倒伏性状显著关联的位点qRLG7,通过基因表达水平分析和候选基因关联分析确定调控水稻抗倒伏性的候选基因,在分析候选... 详细信息

为进一步挖掘控制水稻抗倒伏的基因,以524份水稻种质资源为材料,采用GWAS(genome-wide association analysis)鉴定与抗倒伏性状显著关联的位点qRLG7,通过基因表达水平分析和候选基因关联分析确定调控水稻抗倒伏性的候选基因,在分析候选基因的表达特征和启动子区自然变异基础上利用CRISPR-Cas9技术构建2个候选基因的突变体家系,考察转基因材料的抗倒伏性状。结果显示,编码肌醇-1-单磷酸酶的2个串联排列基因LOC_Os07g37220和LOC_Os07g37230在离茎秆基部5 cm节间中的表达量显著高于其余候选基因,而且这2个候选基因的表达量在极端抗倒伏和易倒伏2组材料中存在极显著差异;通过候选基因关联分析发现这2个基因启动子区的SNP与离基部5 cm茎秆直径(CD5)的表型值显著关联,且基于显著关联SNP的2种单倍型的CD5表型值存在显著差异,这2个候选基因的2种单倍型启动子活性检测结果也表明2种单倍型之间存在极显著差异;2个基因的功能缺失突变体植株在基部节间抗折力、茎秆厚度、茎秆直径以及株高和穗质量等性状方面与野生型对照存在显著差异。结果表明,候选基因LOC_Os07g37220和LOC_Os07g37230具有一定的抗倒伏功能。

关键词：水稻抗倒伏关联分析候选基因肌醇-1-单磷酸酶(IMP)

原位细胞电纺技术及其在创面修复中的应用研究进展

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中华烧伤与创面修复杂志 2024年第7期40卷 694-698页

作者：刘华振张毅高闯陆春祥郭子龙孙文彬肖仕初刘媛媛上海大学医学院上海200444 上海大学机电工程及自动化学院上海200444 海军军医大学第一附属医院烧伤外科上海200433

目前在临床上实现创面的便捷快速修复的策略有限。近年来,在原位静电纺丝(IS-E)技术的基础上,发展出了原位细胞电纺(IS-CE)技术,其通过将活细胞封装在微纳米纤维中,原位构建出活体纤维组织支架,并在创面修复的应用中取得一定进展,但该... 详细信息

目前在临床上实现创面的便捷快速修复的策略有限。近年来,在原位静电纺丝(IS-E)技术的基础上,发展出了原位细胞电纺(IS-CE)技术,其通过将活细胞封装在微纳米纤维中,原位构建出活体纤维组织支架,并在创面修复的应用中取得一定进展,但该技术依然存在细胞存活率低和纤维稳定性差等局限。该文综述了IS-E和IS-CE技术的现状以及IS-CE技术在创面修复中的应用,此外,重点探讨了将IS-CE技术应用于创面治疗的优势、局限性和改进方法,以期为IS-CE技术在组织工程和创面修复中的应用提供参考依据。

关键词：纳米纤维组织支架组织工程原位细胞电纺创面修复