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Sparse and Low-Rank Covariance Matrix Estimation

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Journal of the Operations Research Society of China 2015年第2期3卷 231-250页

作者： Sheng-Long Zhou Nai-Hua Xiu zi-yan luo Ling-Chen Kong Department of Applied Mathematics Beijing Jiaotong UniversityBeijing 100044China State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong UniversityBeijing 100044China

This paper aims at achieving a simultaneously sparse and low-rank estimator from the semidefinite population covariance *** first benefit from a convex optimization which develops l1-norm penalty to encourage the sparsity and nuclear norm to favor the low-rank *** the proposed estimator,we then prove that with high probability,the Frobenius norm of the estimation rate can be of order O(√((slgg p)/n))under a mild case,where s and p denote the number of nonzero entries and the dimension of the population covariance,respectively and n notes the sample ***,an efficient alternating direction method of multipliers with global convergence is proposed to tackle this problem,and merits of the approach are also illustrated by practicing numerical simulations.

关键词： Covariance matrix Sparse and low-rank estimator Estimation rate Alternating direction method of multipliers

Robotic total gastrectomy for carcinoma in the remnant stomach:a comparison with laparoscopic total gastrectomy

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Gastroenterology Report 2021年第6期9卷 583-588页

作者： Zheng-yan Li Jia-Jia Liu Pei-Wu Yu Yong-Liang Zhao yan Shi zi-yan luo Bin Wu Jun-Jie Wang Feng Qian Department of General Surgery Center for Minimally Invasive Gastrointestinal SurgerySouthwest HospitalThird Military Medical UniversityChongqingP.R.China

Background Total gastrectomy for carcinoma in the remnant stomach(CRS)remains a technically demanding *** robotic surgery is superior,equal,or inferior to laparoscopic surgery in patients with CRS is *** study was designed to compare the efficacy and safety of robotic total gastrectomy(RTG)and laparoscopic total gastrectomy(LTG)for the treatment of *** In this cohort study,we retrospectively analysed the data from patients who underwent RTG or LTG for CRS at Southwest Hospital(Chongqing,China)between May 2006 and October *** surgical outcomes,post-operative complications,and survival outcomes between the two groups were *** Compared with LTG,RTG was associated with similar effective operation time(272.0 vs 297.9 min,P=0.170),higher total costs(105,967.2 vs 81,629.5 RMB,P0.05).The 3-year disease-free survival and 3-year overall survival rates were comparable between the two groups(65.5%vs 57.5%,P=0.918;69.0%vs 60.0%,P=0.850,respectively).Conclusions RTG is a safe and feasible procedure for the treatment of CRS and could serve as an optimal treatment for CRS.

关键词： robotic gastrectomy laparoscopic gastrectomy total gastrectomy carcinoma in the remnant stomach

论教育强国价值的国家逻辑:以教强国模型构建

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清华大学教育研究 2024年第2期45卷 1-14页

作者：朱旭东郭绒严梓洛北京师范大学教师教育研究中心北京100875 杭州师范大学中国教育现代化研究院浙江杭州311121

新时代背景下的“教育强国”国家重大战略寄托着党和国家对于通过教育建设社会主义现代化强国、实现中华民族伟大复兴的殷切期望和深沉期待。基于社会主义现代化强国模型建构,社会主义现代化强国是国家安全稳定、兴旺发达、文明昌盛、... 详细信息

新时代背景下的“教育强国”国家重大战略寄托着党和国家对于通过教育建设社会主义现代化强国、实现中华民族伟大复兴的殷切期望和深沉期待。基于社会主义现代化强国模型建构,社会主义现代化强国是国家安全稳定、兴旺发达、文明昌盛、人才济济和具有强大国际权威的高水平大国,依赖于安全能力、核心技术创新力、文化软实力、人才竞争力与全球领导力五个核心国家能力的支撑。国家逻辑视角下教育强国价值实质就是以教强国,即通过教育凝聚支持国家发展的五个核心能力,实现以教安邦维护国家安全稳定、以教兴国促进国家兴旺发达、以教育才满足国家人才需要、以教化人建设国家精神文明、以教立世塑造国家国际权威,最终推动社会主义现代化强国的建成,由此构成以教强国模型。以教强国是教育的个体性价值、社会性价值和教育性价值统一于国家发展、回应国家重大发展战略的必然选择,其所内嵌的“教育-国家能力-国家水平”的价值链揭示了教育发展与国家发展的深刻关系,展现了“教育为国”的使命担当。

关键词：教育强国以教强国社会主义现代化强国教育价值模型建构

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Exploring practical methods for detecting k-nonseparability in multipartite quantum states

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 255-256页

作者： Shunlong luo Academy of Mathematics and Systems Science Chinese Academy of Sciences

Quantum entanglement, referred to as “spooky action at a distance” by Einstein, is not only an intriguing and fascinating feature of quantum theory challenging our classical intuitions about locality and correlations, but also has practical and profound implications for quantum technologies. Initially described by Einstein, Podolsky and Rosen, as well as by Schro¨dinger, entanglement now has become a basic and crucial ingredient for both foundational and experimental investigations of the quantum world.

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The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-yan Sun Lingyun Nie Jing Zhang Xue Fang Hongmei luo Chuanhai Fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

Potassium ions and cyano group modified g-C3N4 for effective generation of H2O2 through two-electron oxygen reduction

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Science China Chemistry 2025年第1期68卷 192-200页

作者： Dongying Wang Shulan Pu Yongmin Chen Ke Lei Yujie Duan Linjiao Mao Xuhui Zeng Xi luo Yuntao Zhang Yuqin Dong Jin Zhong Zhang yan Sun School of Mechanical Engineering Chengdu University Department of Chemistry and Biochemistry University of California

Potassium ions （K+） doped graphitic carbon nitride （g-C3N4） was prepared by a thermal etching method using potassium hydroxide （KOH） as an ion *** transform infrared spectroscopy （FTIR） and X-ray photoelectron spectroscopy （XPS）results showed that the generation of the cyano group was detected while introducing K+.Under simulated sunlight irradiation,the sample with a K+doping amount of 10%showed the highest hydrogen peroxide （H2O2） generation rate of2,140.2μmol *** apparent quantum yield （AQY） at 400 nm and the solar-to-chemical conversion （SCC） are 4.35%and1.23%,respectively.K+acted as a bridge between g-C3N4layers,which enhanced charge transfer ***,the cyano group enhanced the adsorption capacity of protons （H+） and promoted the yield of *** catalyst exhibited excellent photocatalytic stability based on four-cycle *** addition,a mechanism study showed that superoxide radicals （·O2-）were the most important active species in the reaction *** production of H2O2was achieved through consecutive single-electron *** study deepens the understanding of the oxygen reduction reaction process and opens up a new venue for improving H2O2generation.

关键词： photocatalysis hydrogen peroxide oxygen reduction reaction potassium doping cyano group

Tilting homeostatic and dyshomeostatic microglial balance in health and disease:transforming growth factor-beta1 as a critical protagonist

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Neural Regeneration Research 2025年第10期20卷 2895-2897页

作者： Nicolas Hugues Yu luo Department of Molecular and Cellular Biosciences University of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program University of CincinnatiCincinnatiOHUSA Division of Immunobiology Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiOHUSA

Adult microglia,by continuously sensing changes in their environment and communicating with nearly all brain cell types,are considered to be the immune sentinels of the *** the healthy central nervous system(CNS),microglia display a unique molecular homeostatic signature(i.e.,Tmem119,P2ry12,Sall1,Siglech,Gpr34,and Hexb)(Figure 1A).

关键词： Figure signature critical

P2Y1 receptor in Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 440-453页

作者： Shan luo Yifei Wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi Guo Bin Hu Haiwen luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability