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Evaluation of Renal Impairment in Patients with Diabetic Kidney Disease by Integrated Chinese and Western Medicine

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Chinese Journal of Integrative Medicine 2023年第4期29卷 308-315页

作者： QU Yi-lun DONG Zhe-yi CHENG Hai-mei LIU Qian WANG Qian YANG Hong-tao MAO Yong-hui LI Ji-jun LIU Hong-fang GENG Yan-qiu HUANG Wen LIU Wen-hu XIE Hui-di peng fei LI Shuang jiang Shuang-shuang LI wei-zhen DUAN Shu-wei FENG Zhe ZHANG wei-guang LIU Yu-ning TIAN Jin-zhou CHEN Xiang-mei Department of Nephrology First Medical Center of Chinese People's Liberation Army General HospitalNephrology Institute of the Chinese People's Liberation ArmyState Key Laboratory of Kidney DiseasesNational Clinical Research Center for Kidney DiseasesBeijing Key Laboratory of Kidney Disease ResearchBeijing 100853China Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine Key Laboratory of Glucolipid Metabolic DisorderMinistry of Education of ChinaInstitute of Chinese MedicineGuangdong Pharmaceutical UniversityGuangdong Traditional Chinese Medicine Key Laboratory for Metabolic DiseasesGuangzhou 510006China Department of Nephrology The First Affiliated Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300193China Department of Nephrology Beijing HospitalBeijing 100730China Department of Nephrology The Forth Medical Center of People's Liberation Army General HospitalBejing 100039China Department of Endocrinology Dongzhimen Hospital of Beijing University of Traditional Chinese MedicineBejing 100700China Department of Nephrology The Third Medical Center of PLA General HospitalBeijing 100039China Department of Nephrology Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Nephrology Beijing Friendship HospitalFaculty of Kidney DiseasesCapital Medical UniversityBeijing 100050China Department of Nephrology Dongzhimen Hospital of Beijing University of Traditional Chinese MedicineBeijing 100700China Three Departments of Encephalopathy Dongzhimen Hospital of Beijing University of Chinese MedicineBeijing 100700China

Objective:To investigate the factors related to renal impairment in patients with diabetic kidney disease(DKD)from the perspective of integrated Chinese and Western ***:Totally 492 patients with DKD in 8 Chinese hospitals from October 2017 to July 2019 were *** to Kidney Disease Improving Global Outcomes(KDIGO)staging guidelines,patients were divided into a chronic kidney disease(CKD)1-3 group and a CKD 4-5 *** data were collected,and logistic regression was used to analyze the factors related to different CKD stages in DKD ***:Demographically,male was a factor related to increased CKD staging in patients with DKD(OR=3.100,P=0.002).In clinical characteristics,course of diabetes>60 months(OR=3.562,P=0.010),anemia(OR=4.176,P60 months,anemia,hyperuricemia,massive proteinuria,atherosclerosis,and blood deficiency syndrome might indicate more severe degree of renal function damage in patients with DKD.(Registration ***03865914).

关键词： diabetickidney disease integrated Chinese and Western medicine Chinese medicine syndrome

Veno-venous extracorporeal membrane oxygenation for patient with a history of open cholecystectomy and acute respiratory distress syndrome caused by coinfection of avian influenza A (H7N9) and Epstein-Barr virus

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Chinese Medical Journal 2019年第11期132卷 1363-1364页

作者： Yong Yuan Wen-Da Guan Hai-Ming jiang Jian-wei Li Bin-fei Li wei-Jia Wang zi-Feng Yang Rong-Chang Chen Nan-Shan Zhong Yun-Ceng Weng Department of Emergency Sun Yat-Sen University Affiliated Zhongshan Hospital Sun Yat-Sen University Zhongshan Guangdong 528403 China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Health the First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510120 China

To the Editor:Most patients infected with avian influenza A (H7N9) rapidly develop progressive pneumonia and acute respiratory distress syndrome (ARDS), a heterogeneous disorder that is refractory to conventional mechanical ventilation. Most H7N9 patients also have underlying disease such as chronic obstructive pulmonary disease, hypertension, diabetes mellitus, and heart diseases, and are more susceptible to coinfections. For these patients with such serious complications, extracorporeal membrane oxygenation (ECMO) support can be adopted as a feasible life-saving therapy Here, we present our successful experience with ECMO utilized in a patient with ARDS and also with H 7N9 and Epstein-Barr virus (EBV) infection.

关键词： Most people are infected with avian influenza A (H7N9) diabetes mellitus avian influenza

Bioanalysis and Pharmacokinetics of Eight Active Components from Huanglian Jiedu Decoction in Rat Plasma by LC-ESI-MS/MS Method

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Chinese Herbal Medicines 2014年第3期6卷 198-210页

作者： Cheng-cheng peng Shu-ping Wang Hui-zi Jin Jian-fei Tao Guo-wei Wang Pan-lei wei Xu-feng Zhang Le Li Run-hui Liu wei-dong Zhang School of Pharmacy Shanghai Jiao Tong University School of Pharmacy Second Military Medical University Pharmacy Department Shanghai Yangsi Hosipital School of Chemistry and Environmental Engineering Shanghai Institute of Technology

Objective To develop a sensitive and rapid liquid chromatography-electrospray ionization-tandem mass spectrometry （LC-ESI-MS/MS） method for the simultaneous determination of wogonin, coptisine, berberine, palmatine, jatrorrhizine, phellodendrine, magnoflorine, and wogonoside in rat plasma and to evaluate the pharmacokinetic characteristics of Huanglian Jiedu Decoction （HJD）. Methods LC separation was performed on an Acquity HSS T3 column （100 mm × 2.1 mm, 1.8 μm） using gradient elution with the mobile phase consisting of acetonitrile and 0.1% formic acid water. The detection was accomplished by using positive electrospray ionization in multiple-reaction monitoring mode. Plasma samples were pretreated by protein precipitation. Results The method showed a good linearity over a wide concentration range （r^2 〉 0.99）. The lower limits of quantification were 0.20 ng/mL for coptisine and phellodendrine, 0.48 ng/mL for berberine, 0.10 ng/mL for jatrorrhizine, 0.32 ng/mL for magnoflorine, 0.30 ng/mL for palmatine, and 4.80 ng/mL for wogonin and wogonoside, respectively. The intra- and inter-day precision of the analytes was less than 12.11%, while the accuracy was between -14.46% and 4.86%. The mean recovery of all the analytes ranged from 93.10% to 110.91%. Conclusion This validated method offers thee advantages of high sensitivity. It is successfully applied to evaluating the pharmacokinetic properties of HJD.

关键词： alkaloid bioanalysis flavonoid Huanglian Jiedu Decoction LC-ESI-MS/MS pharmacokinetics

Solar X-ray and EUV imager on board the FY-3E satellite

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Light(Science & Applications) 2022年第12期11卷 2939-2951页

作者： Bo Chen Xiao-Xin Zhang Ling-Ping He Ke-fei Song Shi-Jie Liu Guang-Xing Ding Jin-Ping Dun Jia-wei Li Zhao-Hui Li Quan-Feng Guo Hai-Feng Wang Xiao-Dong Wang Yun-Qi Wang Hong-Ji Zhang Guang Zhang Zhen-wei Han Shuang Dai Pei-Jie Zhang Liang Sun Yang Liu software engineer peng Wang Kun Wu Chen Tao Shi-Lei Mao Gui Mei Liang Yang Li-Heng Chen Chun-Yang Han Bin Huang Yang Liu mechanical engineer Shuai Ren peng Zhou Ze-Xiwei Xiao-Xue Zhang Yue Zhang Xin Zheng Yang Wang Ya Chen Jing-jiang Xie fei He Qiao Song wei-Guo Zong Xiu-Qing Hu peng Zhang Jing-Song Wang Zhong-Dong Yang Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchunChina State Key Laboratory of Applied Optics Chinese Academy of SciencesChangchunChina National Satellite Meteorological Center China Meteorological AdministrationBeijingChina Key Laboratory of Space Weather National Center for Space WeatherChina Meteorological AdministrationBeijingChina Innovation Center for Fengyun Meteorological Satellite(FYSIC) BeijingChina Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijingChina

The solar X-ray and Extreme Ultraviolet Imager(X-EUVI),developed by the Changchun Institute of Optics,Fine Mechanics and Physics,Chinese Academy of Sciences(CIOMP),is the first space-based solar X-ray and Extreme ultraviolet(EUV)imager of China loaded on the Fengyun-3E(FY-3E)satellite supported by the China Meteorological Administration(CMA)for solar *** started work on July 11,2021,X-EUVI has obtained many solar *** instrument employs an innovative dual-band design to monitor a much larger temperature range on the Sun,which covers 0.6-8.0 nm in the X-ray region with six channels and 19.5 nm in the EUV region.X-EUVI has a field of view of 42′,an angular resolution of 2.5″per pixel in the EUV band and an angular resolution of 4.1″per pixel in the X-ray *** instrument also includes an X-ray and EUV irradiance sensor(X-EUVS)with the same bands as its imaging optics,which measures the solar irradiance and regularly calibrates the solar *** radiometric calibration of X-EUVS on the ground has been completed,with a calibration accuracy of 12%.X-EUVI is loaded on the FY-3E satellite and rotates relative to the Sun at a uniform ***-field calibration is conducted by utilizing successive rotation solar *** agreement between preliminarily processed X-EUVI images and SDO/AIA and Hinode/XRT images indicates that X-EUVI and the data processing algorithm operate properly and that the data from X-EUVI can be applied to the space weather forecast system of CMA and scientific investigations on solar activity.

关键词： image instrument Solar

整合性神经肌肉训练对提高女子运动员运动表现及预防运动损伤的影响

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体育科学 2017年第2期37卷 66-75页

作者：何鹏飞董范姜自立中国地质大学(武汉)体育部湖北武汉430074 清华大学体育部北京1000841

通过一个纵向的前、后测试来量化神经肌肉训练对于提高女子足球运动员的运动表现以及预防运动损伤的影响,分别在训练干预前、后进行了运动能力测试和生物力学测试。假设该训练可以显著提高运动表现(垂直跳、侧向单脚跳、速度和灵敏性、... 详细信息

通过一个纵向的前、后测试来量化神经肌肉训练对于提高女子足球运动员的运动表现以及预防运动损伤的影响,分别在训练干预前、后进行了运动能力测试和生物力学测试。假设该训练可以显著提高运动表现(垂直跳、侧向单脚跳、速度和灵敏性、卧推和深蹲最大力量)以及改善下肢动作模式(提高关节活动度和降低膝内翻和外翻扭矩)。结果表明,训练干预后,实验组与未进行整合性神经肌肉训练的对照组相比,纵跳、单脚侧跳、速度、灵敏性、卧推和深蹲1RM、膝关节活动度以及膝关节内翻和外翻的力矩均有了统计学意义上的显著提高(P<0.05)。研究结论:整合性神经肌肉训练重视屈膝落地动作以及稳定性动作练习,改变了膝关节发力的生物力学模式,尤其是在跳深落地瞬间的屈膝动作有明显改善,提高动作生物力学合理性,而且能够直接提高运动表现和动作质量。建议:在以后的训练中,应合理的结合超等长训练、抗阻力量训练、核心稳定性训练、平衡训练以及速度灵敏训练等训练方法,这些训练的累积效果可以有效提高运动员的运动表现和提高下肢运动生物力学的合理性,降低运动损伤。

关键词：整合性神经肌肉训练运动表现运动损伤

关于CTL与EAGLE两种规划扩展目标表示语言的语义比较

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计算机学报 2009年第1期32卷 86-96页

作者：黄巍姜云飞文中华彭宏华南理工大学计算机科学与工程学院广州510641 中山大学软件研究所广州510275 湘潭大学信息工程学院湖南湘潭411105

在不确定的智能规划领域中,CTL和EAGLE是两种重要的扩展目标表示语言.虽然与CTL相比EAGLE具有可以表示规划意图和失败处理机制的特点,但是有关严格比较这两种目标表示语言语义的研究工作还不多.文章在规划的执行结构这一语义层次上对这... 详细信息

在不确定的智能规划领域中,CTL和EAGLE是两种重要的扩展目标表示语言.虽然与CTL相比EAGLE具有可以表示规划意图和失败处理机制的特点,但是有关严格比较这两种目标表示语言语义的研究工作还不多.文章在规划的执行结构这一语义层次上对这两种语言做了严格的比较,证明了对于许多包括原来曾被认为无法用CTL表示的EAGLE规划目标而言,都存在着一个与之语义等价的CTL规划目标,并且进一步分析了这两种语言在表示规划目标和指导规划求解这两个层次上的优缺点.

关键词：不确定的智能规划扩展的规划目标执行结构 CTL EAGLE

压裂-注氮原位裂解油页岩加热工艺及传热模拟

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东北大学学报（自然科学版） 2015年第9期36卷 1353-1357,1368页

作者：姜鹏飞孙友宏郭威李强吉林大学建设工程学院吉林长春130026

提出了一种油页岩地下原位转化的新方法,即压裂-注氮原位裂解油页岩技术.油页岩储层压裂后,在加热井内下入电加热器,然后向井内注入氮气,利用加热后的高温氮气原位裂解油页岩.介绍了该方法与传统的电加热法和对流加热法相比的优势,以及... 详细信息

提出了一种油页岩地下原位转化的新方法,即压裂-注氮原位裂解油页岩技术.油页岩储层压裂后,在加热井内下入电加热器,然后向井内注入氮气,利用加热后的高温氮气原位裂解油页岩.介绍了该方法与传统的电加热法和对流加热法相比的优势,以及特别适用的地层,并且对加热氮气过程进行了传热模拟,优化了气体加热器的参数,确定加热器的最佳长度为30 m,其热流密度为11 k W/m2.针对本工艺方法特别适用的薄层油页岩地下原位开采,进行了地层加热时间的传热模拟,确定了80 d即可将井距15 m,矿层1.5 m厚的油页岩加热到裂解温度,较电加热法和对流加热法的加热时间明显缩短.

关键词：油页岩气体加热器注氮气传热模拟加热时间

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不同激励模式下桥梁实测阻尼比差异

振动与冲击 2016年第3期35卷 62-67页

作者：李湛李鹏飞姜震宇韦韩交通运输部公路科学研究院北京100088

收集和分析了国内外学者对结构物阻尼比的实测结果,指出了当前桥梁阻尼比研究成果的局限性。为了弥补当前桥梁阻尼比实测结果匮乏的局限,针对三座典型桥梁进行了阻尼比测试,分析了影响桥梁阻尼比的主要因素。该研究发现:桥梁的阻尼比不... 详细信息

收集和分析了国内外学者对结构物阻尼比的实测结果,指出了当前桥梁阻尼比研究成果的局限性。为了弥补当前桥梁阻尼比实测结果匮乏的局限,针对三座典型桥梁进行了阻尼比测试,分析了影响桥梁阻尼比的主要因素。该研究发现:桥梁的阻尼比不是定值,它与桥梁的类型、测试时的激励方式、阻尼比的处理方法、测试环境等有较大的相关性。激励强度越大,测试的阻尼比数值越大。车辆激励作用下的阻尼比数值明显大于环境激励下的阻尼比数值。相同激励模式下,不同的阻尼比处理方法所计算的阻尼比数值差距较大。半功率带宽法计算的阻尼比数值的离散性要大于利用自由衰减法计算的阻尼比。建议桥梁结构阻尼比的测试中需要保证激励的一致性,避免在采样过程中出现激励程度差距较大的激励模式。

关键词：桥梁工程阻尼比激励模式半功率带宽法自由衰减法

基于时域分析法的汽轮机末级叶片颤振预测及分析

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振动与冲击 2015年第11期34卷 194-199页

作者：姜伟谢诞梅陈畅胡鹏飞高尚武汉大学动力与机械学院武汉430072

利用基于流固耦合的时域分析法对某汽轮机末级叶片的颤振问题进行了数值模拟研究。通过对不同工况、不同相位差下叶片振动响应的计算,分析预测了颤振发生的临界流量以及叶片的振型;通过对叶片受力与位移的分析,获得了不同叶高处流体对... 详细信息

利用基于流固耦合的时域分析法对某汽轮机末级叶片的颤振问题进行了数值模拟研究。通过对不同工况、不同相位差下叶片振动响应的计算,分析预测了颤振发生的临界流量以及叶片的振型;通过对叶片受力与位移的分析,获得了不同叶高处流体对叶片的做功,确定了叶片上气动不稳定区域。通过对气动不稳定区压力分布的分析,解释了叶片间相位差影响颤振发作的机理。此外,研究还发现叶片受力与位移之间的相位差是影响叶片气动稳定性的重要因素。

关键词：时域分析法末级叶片颤振流固耦合气动稳定性