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LAZY4 acts additively with the starch-statolithdependent gravity-sensing pathway to regulate shoot gravitropism and tiller angle in rice

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Plant Communications 2024年第10期5卷 154-165页

作者： Wenguang Wang Linzhou Huang Yuqi Song Songtao Gui Jiajia Cao Han Zhang Mengchen Du Jiaze chen Zihao Wang Jie Zhou Xiangbing Meng Dali Zeng Jiayang Li Yonghong Wang National Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100039China Yazhouwan National Laboratory Sanya 572024China College of Advanced Agricultural Sciences Zhejiang A&F UniversityHangzhou 311300China

Rice tiller angle is a key agronomic trait that has significant effects on the establishment of a high-yield rice ***,the molecular mechanism underlying the control of rice tiller angle remains to be clar***,we characterized the novel tiller-angle gene LAZY4(LA4)in rice through map-based ***4 encodes a C3H2C3-type RING zinc-finger E3 ligase localized in the nucleus,and an in vitro ubiquitination assay revealed that the conserved RING finger domain is essential for its E3 ligase *** found that expression of LA4 can be induced by gravistimulation and that loss of LA4 function leads to defective shoot gravitropism caused by impaired asymmetric auxin redistribution upon *** analysis demonstrated that LA4 acts in a distinct pathway from the starch biosynthesis regulators LA2 and LA3,which function in the starch-statolith-dependent *** genetic analysis showed that LA4 regulates shoot gravitropism and tiller angle by acting upstream of LA1.to mediate lateral auxin transport upon *** studies reveal that LA4 regulates shoot gravitropism and tiller angle upstream of LA1.through a novel pathway independent of the LA2-LA3-mediated gravity-sensing mechanism,providing new insights into the rice tiller-angle regulatory network.

关键词： auxin shoot gravitropism tiller angle LAZY4 rice

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高渗压与循环加卸载环境下开挖卸荷岩体力学特性试验研究

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岩土工程学报 2024年第4期46卷 737-745页

作者：陈兴周白亚妮陈莉丽马彬王文瑞龚盛西安科技大学建筑与土木工程学院陕西西安710054

探究高渗压与循环加卸载环境下深部开挖卸荷岩体力学特性的演化规律,有助于揭示复合荷载作用下工程开挖卸荷围岩的变形破坏机理。从区分开挖扰动强度与渗压量级入手,以高渗压环境下遭受开挖扰动的卸荷岩体为对象,开展了考虑特定孔压与... 详细信息

探究高渗压与循环加卸载环境下深部开挖卸荷岩体力学特性的演化规律,有助于揭示复合荷载作用下工程开挖卸荷围岩的变形破坏机理。从区分开挖扰动强度与渗压量级入手,以高渗压环境下遭受开挖扰动的卸荷岩体为对象,开展了考虑特定孔压与循环荷载复合作用条件下的三轴加卸载试验。结果表明:(1.卸荷量级直接影响循环加卸载过程岩样的变形规律及其破坏强度,孔隙水压促进了岩样循环加卸载过程的拉剪破坏;(2)孔压增幅加剧了同量级卸荷岩样循环加卸载过程的延性变形及强度衰减,且卸荷岩样的轴向、环向与体积变形曲线均在2MPa孔压时产生波动;(3)伴随孔压增加,岩样卸荷量级为30%时的环向变形呈先增加后减小的趋势,而岩样卸荷量级为60%时的环向变形呈现先减小后增加的规律;(4)伴随卸荷量级与孔压增加,岩样破坏时端部裂隙的倾角逐渐增大,沿岩样轴向产生的拉剪破裂面愈加凸显。

关键词：深部岩体开挖卸荷高渗压循环加卸载力学特性

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Preparation,characterization,and catalytic performance of a novel methyl-rich Ti-HMS mesoporous molecular sieve with high hydrophobicity

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Science China Chemistry 2010年第6期53卷 1337-1345页

作者： LI XueFeng1.XU ZhiHong1.GAO HuanXin2 & chen QingLing2 1.ollege of Chemistry and Chemical Engineering,Xuchang University,Xuchang 461.00,China 2Shanghai Research Institute of Petrochemical Technology,Shanghai 201.08,China College of Chemistry and Chemical Engineering Xuchang University Xuchang China Shanghai Research Institute of Petrochemical Technology Shanghai China

A novel methyl-rich Ti-containing hexagonal mesoporous silica (Ti-HMS) molecular sieve with high hydrophobicity has been prepared by a two-step method involving co-condensation followed by vapor-phase methyl *** sample was characterized by XRD,N2 adsorption,FTIR,UV-visible and 29Si NMR spectroscopies,TG,ICP-AES,and hydrophilicity measurements,and its catalytic performance was evaluated using the epoxidation of cyclohexene as a probe *** Ti-HMS material retains a typical mesoporous structure and compared with a co-condensed Ti-HMS prepared in a one-step method possesses more methyl groups and higher hydrophobicity,and also exhibits better catalytic activity and selectivity.

关键词： two-step methyl grafting high hydrophobicity methyl-rich Ti-HMS epoxidation of cyclohexene

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Yields,growth and water use under chemical topping in relations to row configuration and plant density in drip-irrigated cotton

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Journal of Cotton Research 2024年第2期7卷 123-136页

作者： Wang Xuejiao Hu Yanping Ji Chunrong chen Yongfan Sun Shuai Zhang Zeshan Zhang Yutong Wang Sen Yang Mingfeng Ji Fen Guo Yanyun Li Jie Zhang Lizhen Xinjiang Agriculture Network Information Center Xinjiang Agrometeorological ObservatoryUrumqi 830002China College of Resources and Environmental Sciences Xinjiang Agricultural UniversityUrumqi 830091China College of Resources and Environmental Sciences China Agricultural UniversityBeijing 100193China China Meteorological Administration Institute of Desert MeteorologyUrumqi 830002China Wulanwusu Agrometeorological Station Shihezi 832199China Xinjiang Academy of Agricultural Sciences China National Cotton R&D CenterUrumqi 830091China

Background Water deficit is an important problem in agricultural production in arid *** the advent of wholly mechanized technology for cotton planting in Xinjiang,it is important to determine which planting mode could achieve high yield,fiber quality and water use efficiency(WUE).This study aimed to explore if chemical topping affected cotton yield,quality and water use in relation to row configuration and plant *** Experiments were carried out in Xinjiang China,in 2020 and 2021.with two topping method,manual topping and chemical topping,two plant densities,low and high,and two row configurations,i.e.,76 cm equal rows and 1.+66 cm narrow-wide rows,which were commonly applied in matching harvest *** topping increased seed cotton yield,but did not affect cotton fiber quality comparing to traditional manual *** equal row spacing,the WUE in higher density was 62.4%higher than in the lower ***,under narrow-wide row spacing,the WUE in lower density was 53.3%higher than in higher one(farmers’practice).For machine-harvest cotton in Xinjiang,the optimal row configuration and plant density for chemical topping was narrow-wide rows with 1. plants m-2 or equal rows with 1. plants *** The plant density recommended in narrow-wide rows was less than farmers’practice and the density in equal rows was moderate with local *** results provide new knowledge on optimizing agronomic managements of machine-harvested cotton for both high yield and water efficient.

关键词： Yield components Fiber quality Transpiration Water use efficiency Heat ratio method(HRM)

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Wafer level bonding using localized radio-frequency induction heating

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Science China(Technological Sciences) 2010年第5期53卷 1252-1257页

作者： chen MingXiang1.2,LIU WenMing1.2,XI YanYan1.2,LIN ChangYong1.2 & LIU Sheng1.2 1.School of Mechanical Science & Engineering,Huazhong University of Science and Technology,Wuhan 430074,China 2 Division of MOEMS,Wuhan National Laboratory for Optoelectronics,Wuhan 430074,China School of Mechanical Science & Engineering Huazhong University of Science and Technology Wuhan China Division of MOEMS Wuhan National Laboratory for Optoelectronics Wuhan China

A wafer level bonding technique by localized induction heating has been developed and demonstrated in this paper.A suitable fabrication process scheme has also been established for the localized induction heating and *** takes only about 20 seconds to complete the bonding *** temperatures of solder loops and the central area of solder loops are above 300°C and below 70°C,*** to the solder reflow,robust and hermetic glass wafer bonding is accomplished,and the average tensile strength is 6.42 ***-heated or over-heated bonding has been found to result in cracks at bonding interfaces and sputtering layer,which degrades the bonding qualities.

关键词： wafer bonding induction heating MEMS MEMS packaging

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Formation of super-concentrated hydrochloric acid in the third phase in tertiary amine N235-PtCl_6^(2-)-HCl system and its influences on the Pt microemulsion extraction

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Science China Chemistry 2009年第11期52卷 1825-1834页

作者： HUANG Kun1.chen Jing1.ZHANG chengFeng1.2,LI ZhiHong3,PAN QingHua1.SUN Yan1.LIU ShaoXuan1.LIU XueXin2,LI WeiHong1.YANG ZhanLan1.WENG ShiFu1.HU TianDou3,XU YiZhuang1.& WU JinGuang1.1.College of Chemistry and Molecular Engineering,Peking University,Beijing 1.0871.China 2 Institute of Chemistry,Chinese Academy of Sciences,Beijing 1.01.0,China 3 Institute of High Energy Physics,Chinese Academy of Sciences,Beijing 1.0049,China College of Chemistry and Molecular Engineering Peking University Beijing China Institute of Chemistry Chinese Academy of Sciences Beijing China Institute of High Energy Physics Chinese Academy of Sciences Beijing China

In this paper,we have investigated the formation of the third-phase in tertiary amine(N235)-PtCl62--HCl system and the microscopic phase structural evolution of platinum-loaded organic phases before and after the occurrence of the *** third-phase is characterized by various spectroscopic techniques,and the small angle X-ray scattering(SAXS) experiments demonstrate the appearance of nano-aggregates,i.e.,water-in-oil reversed micelles,in the third *** experimental results indicate that(1. formation of the third phase is related to the aggregation behaviors of nano-reversed micelles in which a super-concentrated hydrochloric acid formed with the H+ to H2O molar ratio being much higher than that of the conventional 37 wt% saturated hydrochloric acid.(2) The occurrence of the super-concentrated HCl results in a great amount of H+ and Cl-ions enriched and confined within the nano-water pools of W/O reversed micelles in third ***,the coordination behaviors of platinum complex ions in that super-concentrated hydrochloric acid are very different from their corresponding behaviors in bulk aqueous *** is possible that H+ ions participate in the formation of such complexes as HmPtCl6z+ in the super-concentrated hydrochloric acid.(3) The relative contents of various HmPtCl6z+ complexes are different corresponding to the H+ ion concentrations in confined nanowater *** association ability of the acidified tertiary amine N235 molecules(R3NH+) with various HmPtCl6z+ complexes plays an important role in affecting the platinum extraction behaviors.

关键词： solvent extraction third phase super-concentrated hydrochloric acid tertiary amine platinum

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Changes in macrophage infiltration and podocyte injury in lupus nephritis patients with repeated renal biopsy: Report of three cases

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World Journal of Clinical Cases 2024年第1期12卷 188-195页

作者： Shi-Yuan Liu Hao chen Li-Jia He Chun-Kai Huang Pu Wang Zhang-Ru Rui Jue Wu Yang Yuan Yue Zhang Wen-Ju Wang Xiao-Dan Wang Central Laboratory Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceYan'an Hospital Affiliated to Kunming Medical UniversityKunming 650051Yunnan ProvinceChina Department of Nephropathy Yan'an Hospital Affiliated to Kunming Medical UniversityKunming 650051Yunnan ProvinceChina

BACKGROUND In this study,we retrospectively analysed macrophage infiltration and podocyte injury in three patients with diffuse proliferative lupus nephritis(LN)who un-derwent repeated renal *** SUMMARY Clinical data of three diffuse proliferative LN patients with different pathological characteristics(case 1.was LN IV-G(A),case 2 was LN IV-G(A)+V,and case 3 was LN IV-G(A)+thrombotic microangiopathy)were *** patients underwent repeated renal biopsies 6 mo later,and renal biopsy specimens were *** infiltration was assessed by CD68 expression detected by immunohistochemical staining,and an immunofluorescence assay was used to detect podocin expression to assess podocyte *** treatment,Case 1.changed to LN III-(A),Case 2 remained as type V LN lesions,and Case 3,which changed to LN IV-S(A),had the worst *** observed reduced macro-phage infiltration after ***,two of the patients with active lesions after treatment still showed macrophage infiltration in the renal *** treatment,the three patients showed discontinuous expression of ***,the integrity of podocin was restored after treatment in Case *** It may be possible to reverse podocyte damage and decrease the infiltrating ma-crophages in LN patients through effective treatment.

关键词： Lupus nephritis Macrophage Podocyte Repeat renal biopsy Thrombotic microangiopathy Case report

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类器官模型在前列腺癌研究与治疗中的应用

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世界临床药物 2024年第2期45卷 187-191页

作者：陈美琪范淑盼杨云云王娟刘莉王卓海军军医大学第一附属医院药学部上海200433 中国医药工业研究总院药理评价研究中心上海市生物物质成药性公共服务平台上海200437

前列腺癌(prostate cancer,PCa)是男性常见恶性肿瘤之一,由于其高度异质性及耐药性,一般治疗无法使患者获得最大收益。啮齿类动物与人的前列腺发育有较大区别,现有2维模型无法重现PCa患者特性,而类器官体外模型的出现,为PCa研究提供新思... 详细信息

前列腺癌(prostate cancer,PCa)是男性常见恶性肿瘤之一,由于其高度异质性及耐药性,一般治疗无法使患者获得最大收益。啮齿类动物与人的前列腺发育有较大区别,现有2维模型无法重现PCa患者特性,而类器官体外模型的出现,为PCa研究提供新思路,架起2维培养与体内模型之间的桥梁。该文介绍现有的前列腺模型,包括2维细胞系模型,患者来源的异种移植模型(来源系患者、循环肿瘤细胞、诱导多能干细胞的类器官模型)以及患者来源的异种移植的类器官模型,概述其在应用中的优势以及不足之处。

关键词：前列腺癌类器官诱导多能干细胞患者来源的异种移植物

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肠瘘合并严重腹腔感染患者早期肠内营养支持治疗的安全性评估

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中华胃肠外科杂志 2024年第3期27卷 241-246页

作者：谢天陈晨杨栋梁王文越陈芬何一宁王鹏飞李幼生上海交通大学医学院附属第九人民医院普通外科一科上海200011 上海交通大学医学院附属第九人民医院临床研究中心上海200011

目的评估肠瘘合并严重腹腔感染患者早期肠内营养支持治疗(EEN)的安全性。方法采用回顾性队列研究的方法。收集201.年1.1.至2020年1.1.期间,在上海交通大学医学院附属第九人民医院普通外科一科收治的204例肠瘘合并严重腹腔感染患者... 详细信息

目的评估肠瘘合并严重腹腔感染患者早期肠内营养支持治疗(EEN)的安全性。方法采用回顾性队列研究的方法。收集201.年1.1.至2020年1.1.期间,在上海交通大学医学院附属第九人民医院普通外科一科收治的204例肠瘘合并严重腹腔感染患者的临床资料。以入重症监护室(ICU)48 h内是否成功实施肠内营养支持治疗(EN),将患者分为EEN组和延迟EN(DEN)组。主要研究指标为1.0 d病死率;次要研究指标为腹腔出血、感染性休克、腹腔开放、血流感染、机械通气和连续性肾脏替代治疗(CRRT)事件发生率。采用logistic回归对死亡危险因素进行分析。结果两组患者在入ICU时血液学及人口学资料比较差异无统计学意义(均P>0.05)。但EEN组患者感染性休克[31.2%(1./48)比1..4%(24/1.6),χ^(2)=4.99,P=0.025]、CRRT[27.1.(1./48)比9.0%(1./1.6),χ^(2)=8.96,P=0.003]和1.0 d病死率[31.2%(1./48)比7.7%(1./1.6),χ^(2)=1..75,P1.比例显著高于DEN组患者(均P1.082,95%CI:1.027~1.1.9,P=0.003)、急性生理学及慢性健康状况评分(APACHEⅡ评分)越差(OR=1.1.9,95%CI:1.037~1.363,P=0.01.)、C反应蛋白水平越高(OR=1.01.,95%CI:1.004~1.023,P=0.007)和EEN(OR=8.844,95%CI:1.809~43.240,P=0.007)为肠瘘合并严重腹腔感染患者死亡的独立危险因素。结论EEN可导致肠瘘合并严重腹腔感染患者的不良事件发生,增加死亡风险。此类患者的EEN需审慎实施。

关键词：肠瘘腹腔感染危重症医学营养治疗肠内营养支持治疗,早期

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Synergistic photothermal effect and nanoenzyme for efficient antibacterial activity

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Science China Materials 2024年第9期67卷 2985-2994页

作者： Rong Li Shasha chen Xingang Zhang Fan Zeng Xianyin Song Jia Yin Changzhong Jiang Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Key Laboratory for Matter Microstructure and Function of Hunan ProvinceDepartment of Physics and Synergetic Innovation Center for Quantum Effects and ApplicationsHunan Normal UniversityChangsha410081China Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation College of Life SciencesHunan Normal UniversityChangsha410081China College of Materials Science and Engineering Hunan UniversityChangsha410082China

The continuous emergence of drug-resistant bacteria has become a serious threat to human and animal *** new non-antibiotic therapeutic drugs with high efficiency and low resistance is a promising strategy for combating drug-resistant ***,a novel composite structure based on a hollow metal-organic framework(MOF)wrapped Au nanorod and loaded Pt nanoparticles(Au NR@H-ZIF-8@Pt)is designed for combating drug-resistant *** Au NR@H-ZIF-8@Pt composite structures serve a twofold purpose:(1.showing superior photothermal conversion efficiency under near-infrared light irradiation,thus achieving an antibacterial effect based on photothermal effect,and(2)exhibiting high-efficiency peroxidase-like activity,and effectively killing bacteria by reactive oxygen species(ROS)generated in *** combining photothermal and catalytic effects for in vitro antibacterial experiments,Au NR@H-ZIF-8@Pt exhibits efficient,rapid,broad-spectrum antibacterial activity(99.7%for Pseudomonas aeruginosa and 98.3%for Staphylococcus aureus).In addition,in vivo experiments further demonstrate the advantages of the material in promoting bacterial infection wound *** study not only facilitates the design of novel biological nanomaterials,but also provides new ideas for combating drug-resistant bacteria.

关键词： photothermal therapy nanoenzyme antibacterial treatment metal-organic framework

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