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六环石粉体在紫外光固化涂料中的应用研究

林产工业 2024年第3期61卷 15-21页

作者：秦宇婷苗茁张金鹏于建芳内蒙古农业大学材料科学与艺术设计学院内蒙古呼和浩特010018 内蒙古自治区沙生灌木资源纤维化和能源化开发利用重点实验室内蒙古呼和浩特010018

为打破传统有机涂料在应用中的局限性,并增加其功能性,针对具有释放负氧离子功能的保健涂料进行了研究。通过共混法将无机材料六环石粉体加入到紫外光固化涂料中,制备出性能良好的负离子功能保健涂料,并将其用于朴木地板的表面涂饰。同... 详细信息

为打破传统有机涂料在应用中的局限性,并增加其功能性,针对具有释放负氧离子功能的保健涂料进行了研究。通过共混法将无机材料六环石粉体加入到紫外光固化涂料中,制备出性能良好的负离子功能保健涂料,并将其用于朴木地板的表面涂饰。同时,采用正交试验法考察了该涂料的涂布量、辐射能量及六环石粉体添加量对涂膜理化性能和负离子释放量的影响。结果表明:主要影响涂层耐磨性能的因素是辐射能量,主要影响负离子释放量的因素是涂布量。当涂料的涂布量为40 g/m^(2),辐射能量为200 mJ/cm^(2),六环石粉体的添加量为1.%时,制备的涂料性能较优,其漆膜附着力等级为1.,硬度为4H,磨耗量为0.1. g/1.0 r,负离子释放量为795个/cm^(3)。

关键词：共混法保健涂料六环石负离子保健地板

以“肾占位”起病的类鼻疽脓毒症合并噬血细胞综合征1.

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中国感染控制杂志 2024年第2期23卷 238-241页

作者：黄松陈强曾宇陈朝彦广西医科大学第一附属医院重症医学科广西南宁530021 广西医科大学第一附属医院全科医学科广西南宁530021

类鼻疽病是由类鼻疽伯克霍尔德菌感染所致的传染性疾病,其临床表现多样,常反复发作及合并脓毒症,且易误诊误治,故病死率较高。本文分析1.类鼻疽脓毒症合并噬血细胞综合征的病例,并结合国内外文献对该病的临床特点、诊治思路等进一步总... 详细信息

类鼻疽病是由类鼻疽伯克霍尔德菌感染所致的传染性疾病,其临床表现多样,常反复发作及合并脓毒症,且易误诊误治,故病死率较高。本文分析1.类鼻疽脓毒症合并噬血细胞综合征的病例,并结合国内外文献对该病的临床特点、诊治思路等进一步总结,以期降低该病的误诊误治,提升患者存活率。

关键词：类鼻疽类鼻疽伯克霍尔德菌脓毒症噬血细胞综合征

Endoscopic ligation for benign and malignant lesions of upper digestive tract

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World Journal of Gastroenterology 1997年第3期3卷 67-68页

作者： chen Yu Long 1. chen Yong Zhong 1. ZOU Jian Xiang 1.and LI Xue Li 2 Keywords esophageal and gastric varices polyp liver neoplasms Yu-Long chen Yong-Zhong Chen Jian-Xiang Zou Department of Gastroenterology The First Affiliated Hospital of Henan Medical University Zhengzhou 450052 Henan Province China Xue-Li Li Department of Pathology People&#x02032 s Hospital of Henan Province Zhengzhou 450003 Henan Province ChinaAuthor contributions: All authors contributed equally to the work.Correspondence to: Dr. Yu-Long Chen Professor having 30 papers and 3 books published. Department of Gastroenterology The First Affiliated Hospital of Henan Medical University Zhengzhou 450052 Henan Province ChinaTelephone: 0371-3921761

ＥｎｄｏｓｃｏｐｉｃｌｉｇａｔｉｏｎｆｏｒｂｅｎｉｇｎａｎｄｍａｌｉｇｎａｎｔｌｅｓｉｏｎｓｏｆｕｐｐｅｒｄｉｇｅｓｔｉｖｅｔｒａｃｔＣＨＥＮＹｕＬｏｎｇ１，ＣＨＥＮＹｏｎｇＺｈｏｎｇ１，ＺＯＵＪｉａｎＸｉａ... 详细信息

ＥｎｄｏｓｃｏｐｉｃｌｉｇａｔｉｏｎｆｏｒｂｅｎｉｇｎａｎｄｍａｌｉｇｎａｎｔｌｅｓｉｏｎｓｏｆｕｐｐｅｒｄｉｇｅｓｔｉｖｅｔｒａｃｔＣＨＥＮＹｕＬｏｎｇ１，ＣＨＥＮＹｏｎｇＺｈｏｎｇ１，ＺＯＵＪｉａｎＸｉａｎｇ１ａｎｄＬＩＸｕｅＬｉ２Ｓｕ...

关键词： digestive ligation

Does China's digital economy contribute to low-carbon transition?

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Ecological Economy 2024年第2期20卷 102-122页

作者： LI Jun-jun HUANG Xin-yu chen Mu ZHANG Meng-jiang ZHANG Zhen School of Economics Fujian Normal UniversityFuzhou 350007CHINA College of Mechanical and Electrical Engineering Wuyi UniversityNanping 354300CHINA

The digital economy,as a new emerging economic form,has become an important power for realizing Chinese-style modernization and promoting green development in *** paper measures the digital economy and low-carbon transition index based on the data of 30 provinces in China from 201. to 2020 and analyzes the mechanism and path of the digital economy affecting low-carbon transition using the fixed effect panel data model and the threshold effect *** is found that,(1.The digital economy and low-carbon transition in China are various in different regions,with characteristics of being unbalanced and insufficient.(2)The digital economy significantly promotes low-carbon transition,with the greatest influence in the Central region,followed by the Eastern region and the Western *** different dimensions,the development of informatization and digital transactions promote low-carbon transition,but the development of the internet plays an inhibiting role.(3)The higher the degree of urbanization and environmental regulation,the greater the influence of the digital economy on low-carbon transition.

关键词： digital economy low-carbon transition threshold effect model instrumental variables quantile regression

白藜芦醇通过miR-51.-3P/DUSP1.抑制葡萄膜黑色素瘤细胞的自噬并促进细胞凋亡

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中国药理学通报 2024年第2期40卷 292-298页

作者：孙正杨刘楠楠范学菲陈苏环陈唔奇陈广祎邵玉宝陈晓宇安徽医科大学组织胚胎学教研室安徽合肥230032 中国科技大学医院眼科安徽合肥230002 安徽医科大学临床医学系安徽合肥230032 安徽医科大学形态学实验中心安徽合肥230032

目的探究白藜芦醇(resveratrol,RES)抑制葡萄膜黑色素瘤细胞(choroidal melanoma cells,MUM2B)自噬并促进其凋亡的调控作用及机制。方法将MUM2B分为对照组、实验组,分别用不同浓度的RES(0、1.、20、40、60、80μmol·L-1.处理细胞。划... 详细信息

目的探究白藜芦醇(resveratrol,RES)抑制葡萄膜黑色素瘤细胞(choroidal melanoma cells,MUM2B)自噬并促进其凋亡的调控作用及机制。方法将MUM2B分为对照组、实验组,分别用不同浓度的RES(0、1.、20、40、60、80μmol·L-1.处理细胞。划痕实验检测细胞迁移率,CCK-8检测细胞活力,流式细胞术检测细胞凋亡,通过qRT-PCR和Western blot检测miR-51.-3P、DUSP1.及其他目的蛋白的表达,RIP实验验证miR-51.-3P靶向沉默DUSP1.使用miR-51.-3P的mimic,体外评估miR-51.-3P的生物学意义。结果RES抑制了MUM2B细胞的增殖与侵袭,减弱细胞自噬,促进细胞凋亡;MUM2B细胞p-ERK、p-MTOR蛋白表达明显增加,miR-51.-3P表达增加;过表达miR-51.-3P靶向抑制了DUSP1.表达,并促进了MUM2B细胞的凋亡。结论RES通过促进miR-51.-3P的表达靶向抑制DUSP1.从而抑制MUM2B的自噬并促进其凋亡。

关键词：葡萄膜黑色素瘤白藜芦醇 miR-51.-3P DUSP1 自噬凋亡

Effect of Thermal Fatigue Loading on Tensile Behavior of H1. Die Steel with Biomimetic Surface

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Journal of Bionic Engineering 2010年第4期7卷 390-396页

作者： Zhihui Zhang~1.Luquan Ren~1.Hong Zhou~2,Zhiwu Han~1.Xin Tong~3,Yu Zhao~1.Li chen~1.1.Key Laboratory of Bionic Engineering (Ministry of Education,China),Jilin University,Changchun 1.0022,P.R.China 2.Key Laboratory of Automobile Materials (Ministry of Education,China),Jilin University,Changchun 1.0022,P.R.China 3.The Department of Materials Surface Engineering,Guangzhou Research Institute of Non-Ferrous Metals,Guangzhou 51.651.P.R.China Key Laboratory of Bionic Engineering (Ministry of Education China) Jilin University Changchun P. R. China Key Laboratory of Automobile Materials (Ministry of Education China) Jilin University Changchun P. R. China The Department of Materials Surface Engineering Guangzhou Research Institute of Non-Ferrous Metals Guangzhou P. R. China

Biomimetic surface is an effective ways to promote the performance grade and applied range of materials without alteringtheir *** improved properties such as resisting fatigue,enduring wear,etc,have been achieved by applyingbiomimetic morphology or structure to some engineering material *** this paper,aiming to reveal the relationshipbetween thermal cracking behavior and mechanical properties of engineering materials with biomimetic surface,biomimeticspecimens were fabricated using laser technique by imitating the heterogeneous structure on the surface of plant *** of thermal fatigue cycling on the tensile properties of H1. die steel specimens with different surfaces (several types ofbiomimetic surfaces and a smooth surface) was compared and *** a result,due to the coupling effects of themorphological features on the surface and the microstructure characteristics within unit zone,these specimens with biomimeticsurface exhibit remarkably enhanced Ultimate Tensile Strength (UTS) and 0.2% Yield Strength (YS) compared with referencespecimens while corresponding ductility remains largely unaffected even heightened,whether the thermal fatigue loads or *** relative mechanisms leading to these improvements have been discussed.

关键词： biomimetic surface coupling thermal fatigue tensile property H1. steel

Large-scale Proteomic and Phosphoproteomic Analyses of Maize Seedling Leaves During De-etiolation

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Genomics, Proteomics & Bioinformatics 2020年第4期18卷 397-414页

作者： Zhi-Fang Gao zhuo Shen Qing Chao Zhen Yan Xuan-Liang Ge Tiancong Lu Haiyan Zheng Chun-Rong Qian Bai-{1. Wang Key Laboratory of Photobiology CASInstitute of BotanyChinese Academy of SciencesBeijing 100093China Vegetable Research Institute Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of VegetablesGuangzhou 510640China Institute of Crop Cultivation and Farming Heilongjiang Academy of Agricultural SciencesHarbin 150086China Beijing ProteinWorld Biotech Beijing 100012China Center for Advanced Biotechnology and Medicine Biological Mass Spectrometry FacilityRutgers UniversityPiscatawayNJ 08855USA University of Chinese Academy of Sciences Beijing 100049China

De-etiolation consists of a series of developmental and physiological changes that a plant undergoes in response to *** this process light,an important environmental signal,triggers the inhibition of mesocotyl elongation and the production of photosynthetically active chloroplasts,and etiolated leaves transition from the"sink"stage to the"source"***-etiolation has been extensively studied in maize(Zea mays L.).However,little is known about how this transition is *** this study,we described a quantitative proteomic and phosphoproteomic atlas of the de-etiolation process in *** identified 1.,420 proteins in proteome,among which 1.,1.8 proteins were *** addition,8746 phosphorylation sites within 31.0 proteins were *** the combined proteomic and phosphoproteomic data,we identified a total of 1.,436 *** 7.0%(998/1.,1.8)of proteins significantly changed in abundance during *** contrast,26.6%of phosphorylated proteins exhibited significant changes in phosphorylation level;these included proteins involved in gene expression and homeostatic pathways and rate-limiting enzymes involved in photosynthetic light and carbon *** on phosphoproteomic analysis,34.0%(1.57/31.0)of phosphorylated proteins identified in this study contained more than 2 phosphorylation sites,and 37 proteins contained more than 1. phosphorylation sites,indicating that multi-phosphorylation is ubiquitous during the de-etiolation *** results suggest that plants might preferentially regulate the level of posttranslational modifications(PTMs)rather than protein abundance for adapting to changing *** study of PTMs could thus better reveal the regulation of de-etiolation.

关键词： Maize seedling leaves De-etiolation Quantitative analysis Proteome Phosphoproteome

肺腺癌中FAT1.表达及其与免疫细胞浸润关系的研究

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中国肺癌杂志 2024年第2期27卷 109-117页

作者：丁晨赵文浩黄华李永文张展瑞张芮豪王亚楠吴迪陈琛刘红雨陈军石河子大学医学院第一附属医院胸外科石河子832003 天津医科大学总医院肺部肿瘤外科天津300052 天津医科大学总医院天津市肺癌研究所天津市肺癌转移与肿瘤微环境重点实验室

背景与目的肺癌是癌症相关死亡的主要原因。非小细胞肺癌(non-small cell lung cancer,NSCLC)是肺癌最常见的病理分型,其中又以肺腺癌占比最高。非典型性钙黏蛋白1.FAT atypical cadherin 1.FAT1.是一种受体样蛋白,在肺腺癌中存在高频... 详细信息

背景与目的肺癌是癌症相关死亡的主要原因。非小细胞肺癌(non-small cell lung cancer,NSCLC)是肺癌最常见的病理分型,其中又以肺腺癌占比最高。非典型性钙黏蛋白1.FAT atypical cadherin 1.FAT1.是一种受体样蛋白,在肺腺癌中存在高频率突变,其编码的蛋白在细胞黏附、细胞增殖、分化等过程中发挥着重要的作用。本研究旨在研究FAT1.肺腺癌中的表达及与免疫浸润的关系。方法通过下载癌症基因组图谱(The Cancer Genome Atlas,TCGA)和基因型-组织表达(Genotype-Tissue Expression,GTEx)相关数据,获得51.例肺腺癌样本、397例癌旁样本的基因表达水平及相关临床信息。分析肺腺癌组织中FAT1.因mRNA表达水平以及FAT1.因的表达与肺腺癌患者的预后关系,通过通路富集分析探索FAT1.因调控的相关信号通路。利用免疫蛋白印迹检测FAT1.肺上皮细胞和不同肺癌细胞系中的表达差异,免疫组织化学染色法被用于检测FAT1.肺癌和癌旁组织中的表达。结果1.%的肺腺癌患者中存在FAT1.因突变;TCGA数据库数据显示肺腺癌组织中FAT1.mRNA表达显著高于癌旁组织。Kaplan-Meier分析显示FAT1.因表达较高的肺腺癌患者预后较差。通路富集分析表明FAT1.肿瘤发生发展通路相关,且FAT1.表达和免疫细胞浸润密切相关,免疫组化实验证明FAT1.癌组织的表达显著高于癌旁组织。结论肺腺癌组织中FAT1.mRNA呈高表达,高表达的FAT1.mRNA与肺腺癌患者的不良预后相关。FAT1.可能成为潜在的肺癌诊治靶点。

关键词：肺肿瘤 FAT1 预后增殖免疫

Pillar[5]arene based conjugated macrocycle polymers with unique photocatalytic selectivity

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Chinese Chemical Letters 2020年第12期31卷 3225-3229页

作者： Hui Qiang Tao chen {1. Wang Wenqian Li Yunzhe Guo Jie Yang Xueshun Jia Hui Yang Weibo Hu Ke Wen College of Science Shanghai universiryShanghai 200444China Shanghai Advanced Research Intstitute Chinese Academy of SciencesShanghai 201210China University of Chinese Acadeny of Sciences Beijing 100049China School of Physicnl Science and Technology ShanghaiTech UniversityShanghai 201210China

The development of heterogeneous catalysts with substrate shape,size or electronic constitution selectivity is a huge challenge in *** herein is a host-guest interaction strategy to endow photocatalysts with special *** adjusting the precursors,conjugated macrocycle polymers(CMPs)with pillar[5]arene struts(CMP-1.and CMP-2)and a corresponding non-pillar[5]are necontained conjugated organic polymer(COP-1.were prepared and the photocatalytic activities toward sulfide derivatives were *** sulfides showed similar conve rsions when COP-1.was used as a photocatalyst,but exhibited significant differences when it turned to the ***,the conversion yield of S-1.achieved near 1. folds over the one of S-2 when CMP-2 was used as a *** studies confirmed that the"host-guest"effect of pillar[5]arene struts in CMPs was the main cause of the *** present work establishes CMPs as novel heterogeneous photocatalysts with substrate selectivity,and such a method will inspire the researchers concerning preparation of heterogeneous catalysts with excellent selectivity.

关键词： Heterogeneous photocatalysis Selectivity Host-guest Pillararene Sulfide