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三维适形脾区放疗与药物治疗慢性特发性血小板减少性紫癜疗效比较

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临床血液学杂志 2005年第5期18卷 279-280页

作者：任宝志韩磊冯长伟山长平朱培军济宁医学院附属医院肿瘤科山东济宁272029 济宁医学院附属医院血液科

目的:对比分析三维适形脾区放疗与药物治疗对慢性特发性血小板减少性紫癜(CITP)的疗效、不良反应及预后。方法:将60例脾区放射指数较高的CITP患者随机分为2组:三维放疗组(30例)经CT定位、三维适形照射,每次1.8Gy,每周5次,总剂量为30.6Gy... 详细信息

目的:对比分析三维适形脾区放疗与药物治疗对慢性特发性血小板减少性紫癜(CITP)的疗效、不良反应及预后。方法:将60例脾区放射指数较高的CITP患者随机分为2组:三维放疗组(30例)经CT定位、三维适形照射,每次1.8Gy,每周5次,总剂量为30.6Gy;药物治疗组(30例)口服泼尼松30～60mg/d,有效后逐渐减量,再用小剂量维持治疗。结果:三维放疗组与药物治疗组的总有效率分别为87.0%和73.0%,2组疗效比较差异无统计学意义(P>0.05)。结论:三维适形脾区放疗的疗效高,不良反应小,与药物治疗的疗效相当,可成为脾区放射指数较高CITP患者的首选疗法之一,亦可成为脾动脉栓塞复发后的补救治疗。

关键词：紫癜,特发性血小板减少性脾脏放疗预后

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滑翔飞行器速度约束条件下制导律设计

上海航天（中英文） 2024年第4期41卷 141-147页

作者：张佩俊许宏涛姚保江朱建文西安航天动力技术研究所陕西西安710025 火箭军工程大学导弹工程学院陕西西安710025

针对滑翔飞行器速度约束条件下的制导问题,提出一种基于神经网络的制导方法。首先,建立滑翔飞行器弹道优化模型,给出基于高斯伪谱法的弹道优化方法和基于神经网络的制导律模型;其次,为进一步满足速度约束条件,提出了速度控制策略;最后,... 详细信息

针对滑翔飞行器速度约束条件下的制导问题,提出一种基于神经网络的制导方法。首先,建立滑翔飞行器弹道优化模型,给出基于高斯伪谱法的弹道优化方法和基于神经网络的制导律模型;其次,为进一步满足速度约束条件,提出了速度控制策略;最后,将高斯伪谱法获得的最优控制量离散后作为标签数据,利用反向传播(BP)神经网络进行训练,将训练好的网络模型嵌入弹道仿真环境中进行数值计算,并与定攻角剖面和高斯伪谱法离线优化的计算结果进行对比分析。仿真结果表明:提出的制导方法能够在满足速度约束条件下实现制导飞行,具备在线实施的能力和较好的工程适用性,对此类飞行器的制导律设计具有一定的参考意义。

关键词：滑翔飞行器速度约束神经网络高斯伪谱法

Human Settlement Analysis Based on Multi-temporal Remote Sensing Data： A Case Study of Xuzhou City, China

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Chinese Geographical Science 2016年第3期26卷 389-400页

作者： zhu Jishuai TIAN Shufang TAN Kun DU peijun Jiangsu Key Laboratory of Resources and Environment Information Engineering China University of Mining and Technology Xuzhou 221116 China China University of Geosciences Beijing 100083 China Key Laboratory for Satellite Mapping Technology and Applications of State Administration of Surveying Mapping and Geoinformation of China Nanjing University Nanjing 210023 China

To evaluate urban human settlement, we propose a human settlement environment development index(HSEDI) model by choosing vegetation coverage, land surface temperature, impervious surfaces, slope, wetness, and water condition as the evaluation factors. We applied the proposed model to Xuzhou City, Jiangsu Province, China. Landsat-5 Thematic Mapper(TM) images from 1998 to 2010 and digital elevation model(DEM) data with a 30-m resolution were used to calculate the values of the six evaluation factors. The HSEDI value in Xuzhou City was found to be between 2.24 and 8.10 from 1998 to 2010, and it was further divided into five levels, uninhabitable, moderately uninhabitable, generally inhabitable, moderately inhabitable, and inhabitable. The best HSEDI value was in 2007. The generally inhabitable region was about 100.98 km^2, covering 30.87% of the total area in 2007; the moderately inhabitable region was about 170.58 km2 covering 52.15% of the total area; the inhabitable region was about 32.03 km^2, covering 9.79% of the total area; the percentage of the uninhabitable region was zero; and that of the moderately uninhabitable region was very small, less than 1.00%. Moreover, we analyzed the habitability in the respect of spatial patterns and change detection. Results show that the degraded regions of habitability quality are mainly located in the urban fringe and the improved regions are mainly located in the main urban and rural areas. Reason for the degraded habitability quality is the rapid progress of urbanization. However, the increase in urban green spaces and the construction of the main urban area promoted the improved habitability quality. Besides, we further analyzed socio-economic and socio-demographic data to confirm the results of the habitability analysis. The results indicate that the human settlement in Xuzhou City is in a satisfactory condition, but some efforts should be made to control the possible uninhabitable and moderately uninhabitable regions, and

关键词： habitability human settlement Landsat human settlement environment development index(HSEDI) model

来氟米特联合白芍总苷治疗强直性脊柱炎的疗效观察

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中国现代医生 2012年第20期50卷 60-61,63页

作者：蒋琼金小福朱佩君俞萍窦乘华浙江省台州市立医院风湿科浙江台州318000 上海交通大学附属新华医院肾内风湿科上海200092 湖南省永州市中医院内科湖南永州425000

目的探讨来氟米特联合白芍总苷治疗强直性脊柱炎(AS)的疗效及安全性。方法以我院AS患者为研究对象。随机分为试验组(服用来氟米特片和白芍总苷胶囊)和对照组(只服用来氟米特片)。以治疗3个月、6个月和12个月BASDAI、VAS评分及血沉变化... 详细信息

目的探讨来氟米特联合白芍总苷治疗强直性脊柱炎(AS)的疗效及安全性。方法以我院AS患者为研究对象。随机分为试验组(服用来氟米特片和白芍总苷胶囊)和对照组(只服用来氟米特片)。以治疗3个月、6个月和12个月BASDAI、VAS评分及血沉变化评价治疗效果,并记录治疗过程中药物不良反应。结果治疗后3个月与治疗前比较,试验组BASDAI和血沉明显低于对照组,差异有统计学意义(P<0.05);治疗后6个月和治疗后12个月,试验组BASDAI、VAS评分及血沉均低于相同时点的对照组,差异有统计学意义(P<0.05)。结论来氟米特联合白芍总苷较单用来氟米特可更好地控制AS活动,且不增加不良反应。

关键词：来氟米特白芍总苷强直性脊柱炎

基于相似度分析的工单回复与审核平台建设方案

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自动化应用 2022年第2期 101-103,111页

作者：赵哲源秦海波朱培军胡玮玮陈诚国网江苏省电力有限公司淮安供电分公司江苏淮安223002

当前工单回复内容的规范性主要依靠工单回复人员的自觉性,且需要人员进行逐项审核。针对这一情况,提出一种基于相似度分析的工单回复与审核平台建设方案。首先,建立不同类型、不同诉求下的95598用户用电诉求工单回复模板和优秀范例;其次... 详细信息

当前工单回复内容的规范性主要依靠工单回复人员的自觉性,且需要人员进行逐项审核。针对这一情况,提出一种基于相似度分析的工单回复与审核平台建设方案。首先,建立不同类型、不同诉求下的95598用户用电诉求工单回复模板和优秀范例;其次,从用户、社区、台区、线路、时间和诉求内容等方面进行工单的相似度分析,迅速找到相似历史工单,以供处置人员参考;最后,研究处置回复内容的预审核功能,自动审核回复内容的逻辑性错误。提高了工单回复质量和一次通过率,高效、快速响应用户诉求,提升了公司服务质量和服务效率。

关键词：工单回复工单审核相似度分析

Measurement of ecological capital of Chinese terrestrial ecosystem based on remote sensing

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Science China Earth Sciences 2005年第6期48卷 786-796页

作者： PAN Yaozhong SHI peijun zhu Wenquan GU Xiaohe FAN Yida LI Jing Key Laboratory of Environmental Change and Natural Disaster of the Ministry of Education of China Beijing Normal UniversityBeijing 100875China

The biosphere of the Earth is essential to human survival and *** services of ecosystems are critical to the functioning of the Earth’s life-support *** contribute to human welfare both directly and *** capital refers to the sum of the direct biological resources value and the indirect ecosystem services *** is necessary to estimate the ecological capital in order to bring it to the society and market economic system,and draw the social attention to ecological environment *** estimation model for eco-logical capital based on remote sensing is presented in this *** parameters in the model are quantitatively measured using NOAA/AVHRR and other ancillary data,including the land cover types,the vegetation coverage,and the vegetation net primary productivity(NPP)of ter-restrial *** on the economic parameters in previously published studies and a few original calculations,the annual ecological capital of the entire terrestrial ecosystem of China is quantitatively estimated at 6.44 trillion(10^(12))yuan(RMB),and the spatial distribution of the eco-logical capital is also *** ecological methods to ecological capital measurement are based on homogeneous plot scales,and the regional scaling is a key problem in their *** the proposed remote sensing approach,it provides a new method to ecological capital measurement completely based on observation *** can not only overcome the re-gional scaling problem easily,but also allows the ecological capital to be estimated objectively and spatial-explicitly.

关键词： terrestrial ecosystem ecological capital remote sensing quantitative measurement.

Sediment source and environment evolution in Taiwan Island during the Eocene–Miocene

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Acta Oceanologica Sinica 2021年第2期40卷 114-122页

作者： Yuanli Hou Weilin zhu peijun Qiao Chi-Yue Huang Yuchi Cui Xianbo Meng State Key Laboratory of Marine Geology Tongji UniversityShanghai 200092China

Taiwan Island’s outcropping strata can provide important insights into the sedimentary environment and source development of the southeast China *** research is based on the Eocene–Miocene strata of the Tsukeng area in the central Western Foothills,northeast shoreline of Taiwan Island and two sites of the East China Sea Shelf Basin(ECSSB),using petrology and detrital zircon U-Pb age for the *** show that central and northeast Taiwan Island experienced a transformation from continental to marine facies during the Eocene–Miocene,and the sandstone maturity changed with *** analysis shows that sediments from the Eocene–early Oligocene strata mainly originated from near-source Mesozoic rocks,whose zircon age is consistent with the igneous rock in the surrounding area and coastal Cathaysia,showing 120 Ma and 230 Ma peaks in the age spectrum *** the late Oligocene,peaks of 900 Ma and 1800 Ma are seen,indicating that deposition of matter from the old block *** sediments could be a mixture of the surrounding Mesozoic volcanic and fewer pre-Cambrian rocks sourced from the coastal river and sporadic old basement in the ECSSB instead of longdistance transportation.

关键词： Taiwan Island sedimentary source sandstone zircon sedimentary environment

A quantitative performance comparison of paddy rice acreage estimation using stratified sampling strategies with different stratification indicators

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International Journal of Digital Earth 2018年第10期11卷 1001-1019页

作者： peijun Sun Jinshui Zhang Russell G.Congalton Yaozhong Pan Xiufang zhu State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijingPeople’s Republic of China Institute of Remote Sensing and Engineering Faculty of Geographical ScienceBeijing Normal UniversityBeijingPeople’s Republic of China Department of Natural Resources and the Environment University of New HampshireDurhamNHUSA

Various indicators derived from thematic maps have been widely used to determine the strata needed to perform stratified ***,these indicators typically do not quantify the spatial errors in the crop thematic maps that are needed to reduce the *** address this lack of error information,this paper introduces a hybrid entropy indicator(HEI).Two conventional indicators,the acreage indicator(AI)and the fragmentation indicator(FI),were also evaluated to compare the results of the three indicators in a homogeneous agricultural area(Pinghu,PH)and a heterogeneous agricultural area(zhuji,ZJ).The results show that HEI performs the best in heterogeneous areas with the lowest coefficient of variation(CV)(as low as 1.59%)and also has the highest estimation accuracy with the lowest standard deviation of *** both areas,the performances of HEI and AI are very similar,and better than *** results highlight that the HEI should be considered as an effective indicator and used in place of AI and FI to help improve sampling efficiency of crop acreage estimation,while FI is not ***,the positive performance achieved using HEI indicates the potential for incorporating thematic map uncertainty information to improve sampling efficiency.

关键词： Acreage estimation stratification sampling hybrid entropy indicator acreage indicator fragmentation indicator

白藜芦醇与伊马替尼协同作用对K562细胞生物学行为的影响

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临床血液学杂志 2017年第5期30卷 705-709页

作者：王晓军茹甫毅吴双有朱卫民田培军安康市中心医院陕西安康725000

目的:探讨白藜芦醇对人白血病细胞增殖的影响及机制。方法:采用不同浓度白藜芦醇及伊马替尼对K562细胞进行干预,通过MTT法、台盼蓝染色观察细胞增殖,caspase-3活性检测、Hoechst 33258染色及流式细胞术观察细胞凋亡情况和细胞增殖抑制率... 详细信息

目的:探讨白藜芦醇对人白血病细胞增殖的影响及机制。方法:采用不同浓度白藜芦醇及伊马替尼对K562细胞进行干预,通过MTT法、台盼蓝染色观察细胞增殖,caspase-3活性检测、Hoechst 33258染色及流式细胞术观察细胞凋亡情况和细胞增殖抑制率,利用中效原理计算出各时间段内白藜芦醇、伊马替尼对K562细胞增殖抑制的中效浓度,以检测二者有无联合增效作用。结果:不同剂量白藜芦醇、伊马替尼单独作用和联合作用对K562细胞均有生长抑制作用,在一定范围内呈剂量、时间依赖性,2种药物联合有协同增效作用。随着白藜芦醇或伊马替尼浓度升高,其caspase-3活性逐渐增强。白藜芦醇、伊马替尼单独作用和联合作用对人白血病细胞K562均有凋亡作用,且联合用药组随着白藜芦醇或伊马替尼浓度的增加,K562细胞的凋亡率也逐渐增加。结论:白藜芦醇及伊马替尼对白血病K562细胞株均有促进凋亡作用,联合用药可明显增加其凋亡率。

关键词：白血病白藜芦醇伊马替尼凋亡