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Non-coding RNAs in acute ischemic stroke:from brain to periphery

Neural Regeneration Research 2025年第1期20卷 116-129页

作者： Shuo Li Zhaohan Xu Shiyao Zhang Huiling Sun Xiaodan Qin Lin zhu Teng Jiang Junshan Zhou Fuling Yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress

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Change of Work Function of Pd, Ag, K on Al(001) as a Function of External Electric Field

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Chinese Physics Letters 2001年第8期18卷 1111-1113页

作者： zhu Zi-Zhong HOU zhu-Feng HUANG Mei-chun HUANG rong-Bin ZHENG Lan-Sun Department of Physics Xiamen UniversityXiamen 361005 State Key Laboratory for Physical Chemistry of Solid Surfaces Xiamen UniversityXiamen 361005

We present a local density functional calculation of the effect of an external electric field on the work function change of Pd and Ag adsorption on an Al(001)*** adsorption of K has also been considered for *** found that the work functions for all the systems increased linearly when the strength of external electric field was *** the polarized electrons at the interstitial regions between the adsorbate and substrate for Pd/Al(001)and Ag/Al(001)react to the external electric field differently,the subtle differences between Pd/Al(001)and Ag/Al(001)bondings has been characterized through the comparison of slopes of the work function change versus electric field.

关键词： surface. field. adsorption

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Analysis of sliding electric contact characteristics in augmented railgun based on the combination of contact resistance and sliding friction coefficient

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Defence Technology（防务技术） 2020年第4期16卷 747-752页

作者： chun-yan zhu Bao-ming Li National Key Laboratory of Transient Physics Nanjing University of Science and TechnologyChina

The contact resistance between the armature and rails is an important indicator of the contact characteristics in electromagnetic *** the contact resistance depends not only on the contact state but also on the contact stress and temperature,there are some limitations in analyzing the contact characteristics using only the contact *** this paper,the contact characteristics of the augmented railgun are analyzed by the combination of contact resistance and sliding friction ***,the theoretical calculation model of the contact resistance and friction coefficient of the augmented electromagnetic railgun is *** the contact resistance and friction coefficient are calculated by the measured values of the muzzle voltage,rail current and armature ***,the contact characteristics are analyzed according to the features of the waveforms of the contact resistance and the friction coefficient,and the analysis conclusions are verified by experimental rail *** results showed that:the aluminum melt film gradually formed on the contact surface reduces the contact resistance and the friction coefficient;the wear and erosion of the armature cause deterioration of the contact state;after the transition,the reliability of the sliding contact between the armature and rails decreases,resulting in an increase in contact resistance.

关键词： Augmented railgun Contact resistance Friction coefficient Contact characteristics

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Characteristics of a coherent jet enshrouded in a supersonic fuel gas

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International Journal of Minerals,Metallurgy and Materials 2020年第2期27卷 173-180页

作者： Fei Zhao rong zhu Wen-rui Wang Key Laboratory of Fluid Interaction with Material University of Science and Technology BeijingBeijing 100083China National Center for Materials Service Safety University of Science and Technology BeijingBeijing 100083China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of Mechanical Engineer University of Science and Technology BeijingBeijing 100083China

Based on a current coherent jet,this study proposes a supersonic combustion(SC)coherent jet in which the main oxygen jet is surrounded by a supersonic fuel *** characteristics of the proposed coherent jet are analyzed using experimental methods and numerical simulations in the high-temperature environment of electric arc furnace(EAF)*** SC coherent jet achieved stable combustion in the EAF steelmaking *** simulated combustion temperature of the supersonic shrouding methane gas was 2930 K,slightly below the theoretical combustion temperature of methane–oxygen *** high speed and temperature of the supersonic flame effectively weakened the interaction between the main oxygen jet and the external ambient gas,inhibiting the radial expansion of the main oxygen jet and maintaining its high speed and low turbulence over a long *** features improved the impact capacity of the coherent jet and strengthened the stirring intensity in the EAF bath.

关键词： EAF steelmaking coherent jet supersonic shrouding fuel gas supersonic combustion field characteristics

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Structure and magnetic properties of nanocrystalline dysprosium powders

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Rare Metals 2020年第1期39卷 28-35页

作者： Hong-Jian Li Qiong Wu Ming Yue Yu-Qing Li rong-chun zhu Jing-Ming Liang Jiu-Xing Zhang College of Materials Science and Engineering Key Laboratory of Advanced Functional MaterialsMinistry of Education of ChinaBeijing University of TechnologyBeijing100124China

In this current study,nanocrystalline Dy powders were prepared by melt-spinning and subsequent highenergy *** effect of ball-milling time on the structure and magnetic properties of the powders was *** crystal structure and microstructure of the melt-spun ribbons and ball-milled powders were observed by X-ray diffraction(XRD),scanning electron microscopy(SEM)and transmission electron microscopy(TEM).Magnetic measurement of all samples was performed with vibrating sample magnetometer(VSM).XRD results indicate that the average crystal grain size of the powders decreases from 90.09 nm of the ribbons to 10.42 nm of the4-h ball-milled *** TEM observation shows that the grains are fine and *** Neel temperature(TN)decreases from 182 K of the ribbons to 172 K of the powders,while the Curie temperature(TC)increases from100 to 130 K,demonstrating that the grain size has substantial influence on the magnetic transition ***,at 60 K,as the ball-milling time increases,the coercivity of the powders increases first,peaking at 0.48 T for 2-h milling,then drops again,while the remanence of the powders decreases monotonic *** a result,the powders milled for 2 h exhibit an optimal maximum energy product of 64.0 kJ·m-3,demonstrating the good potential of these powders as a permanent magnet at low temperatures.

关键词： Dysprosium Nanocrystalline Low temperature Magnetic properties

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Wafer-Scale Ag₂S-Based Memristive Crossbar Arrays with Ultra-Low Switching-Energies Reaching Biological Synapses

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NANO-MICRO LETTERS 2025年第1期17卷 1-12页

作者： zhu, Yuan Nyberg, Tomas Nyholm, Leif Primetzhofer, Daniel Shi, Xun Zhang, Zhen Uppsala Univ Dept Elect Engn Div Solid State Elect S-75121 Uppsala Sweden Uppsala Univ Dept Chem Uppsala Sweden Uppsala Univ Dept Phys & Astron Uppsala Sweden Chinese Acad Sci Shanghai Inst Ceram State Key Lab High Performance Ceram & Superfine M Shanghai 200050 Peoples R China

Memristive crossbar arrays (MCAs) offer parallel data storage and processing for energy-efficient neuromorphic computing. However, most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor (CMOS) technology still suffer from substantially larger energy consumption than biological synapses, due to the slow kinetics of forming conductive paths inside the memristive units. Here we report wafer-scale Ag2S-based MCAs realized using CMOS-compatible processes at temperatures below 160 degrees C. Ag2S electrolytes supply highly mobile Ag+ ions, and provide the Ag/Ag2S interface with low silver nucleation barrier to form silver filaments at low energy costs. By further enhancing Ag+ migration in Ag2S electrolytes via microstructure modulation, the integrated memristors exhibit a record low threshold of approximately - 0.1 V, and demonstrate ultra-low switching-energies reaching femtojoule values as observed in biological synapses. The low-temperature process also enables MCA integration on polyimide substrates for applications in flexible electronics. Moreover, the intrinsic nonidealities of the memristive units for deep learning can be compensated by employing an advanced training algorithm. An impressive accuracy of 92.6% in image recognition simulations is demonstrated with the MCAs after the compensation. The demonstrated MCAs provide a promising device option for neuromorphic computing with ultra-high energy-efficiency.

关键词： Wafer-scale Ag2S films Reactive sputter Silver nucleation Ag+ migration Energy-efficient neuromorphic computing

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Fabrication and Characterization of Tailored TiO_2 and WO_3/MWCNT Composites for Methylene Blue Decomposition

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催化学报 2011年第6期32卷 926-932页

作者： zhu Lei MENG Zeda OH Won-chun Department of A dvanced Materials Science ＆ Engineering Hanseo University Chungnam 356-706 Korea

A sol-gel method was used to prepare WO3/MWCNT-TiO2 *** photocatalytic activities were evaluated by the degradation of methylene blue (MB) solution under UV *** catalysts were characterized by X-ray diffraction,specific surface area measurement,energy-dispersive X-ray analysis,transmission and scanning electron *** MB solutions of 100 ml were photodegraded by a small amount of the WO3/MWCNT-TiO2 composite under UV light *** photocatalytic data showed that the WO3/MWCNT-TiO2 composite achieved a high rate of MB *** was attributed to the use of MWCNT which can absorb UV light to create photo-induced electrons,strong adsorption of dye molecules on the photocatalyst,and reduced recombination rate of electron-holes in the WO3/MWCNT-TiO2 composite due to the introduction of the WO3 semiconductor.

关键词：固体超强碱氧化钙硝酸钾氧化铝氧化锆氢氧化钾硝酸钙

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High-performance, low-cost joint equalizer and trellis decoder for 1000BASE-T gigabit Ethernet transceiver

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The Journal of China Universities of Posts and Telecommunications 2007年第2期14卷 106-111页

作者： zhu Yue rong Meng-tian Department of Electronic Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai 200240 China

This article presents an M-algorithm （MA） decoder with 4 survival paths （MA4） for Institute of Electrical and Electronics Engineers （IEEE） 802.3ab 1000BASE-T gigabit Ethernet （GbE） transceiver. To fulfill the entire requirements, various methods were introduced to accelerate the MA4 decoder while retaining the desired high performance and low complexity. Optimized look-ahead architecture was employed to solve the critical path problem with minimal gate consumption. Symbol compression methods saved registers during pipeline stages. A sorting network accelerated the kernel sorting operation at low hardware cost by utilizing the special characteristics of MA4. Simulations and synthesis results show that the proposed decoder achieves 125 MHz clock frequency and l Gb/s throughput in 1.8 V 0.18μm standard cell complementary metal-oxide-semiconductor （CMOS） process. It achieves additional 0.4 dB coding gain over 14tap parallel decision feedback decoder （PDFD） with 39% area reduction.

关键词： 1000BASE-T GbE M-algorithm PDFD look-ahead technology

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Upper Bounds for Ruin Probabilities under Stochastic Interest Rate and Optimal Investment Strategies

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Acta Mathematica Sinica,English Series 2012年第7期28卷 1421-1430页

作者： Jin zhu LI rong WU School of Mathematical Sciences and LPMC Nankai University

In this paper, we study the upper bounds for ruin probabilities of an insurance company which invests its wealth in a stock and a bond. We assume that the interest rate of the bond is stochastic and it is described by a Cox-Ingersoll-Ross （CIR） model. For the stock price process, we consider both the case of constant volatility （driven by an O U process） and the case of stochastic volatility （driven by a CIR model）. In each case, under certain conditions, we obtain the minimal upper bound for ruin probability as well as the corresponding optimal investment strategy by a pure probabilistic method.

关键词： Cox Ingersoll-Ross model jump-diffusion model optimal investment Ornstein Uhlen- beck (O-U) process ruin probability stochastic interest rate

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Asymptotic Ruin Probabilities of the Renewal Model with Constant Interest Force and Dependent Heavy-tailed Claims

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Acta Mathematicae Applicatae Sinica 2011年第2期27卷 329-338页

作者： Jin-zhu Li rong Wu School of Mathematical Sciences and LPMC Nankai University Tianjin 300071 China

In this paper, we investigate the asymptotic behavior for the finite- and infinite-time ruin probabilities of a nonstandard renewal model in which the claims are identically distributed but not necessarily inde- pendent. Under the assumptions that the identical distribution of the claims belongs to the class of extended regular variation （ERV） and that the tails of joint distributions of every two claims are negligible compared to the tails of their margins, we obtain the precise approximations for the finite- and infinite-time ruin probabilities.

关键词： asymptotic behavior extended regular variation negligible joint tails ruin probability

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