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Clinical management of a rare melanoma case arising from congenital melanocytic nevus

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Genes & Diseases 2024年第3期11卷 79-82页

作者： Ruixin Jiang Yan Wang xuhui Ma Xinyang Xuanyuan Yanjie Zhang Bin Jiang Weizhen Zhang Hanlin Zeng Department of Oncology Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 201900China Department of Oncology The Third People's Hospital of ZhengzhouZhengzhouHenan 450000China Department of Oral&Maxillofacial-Head and Neck Oncology Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200125China Shanghai Institute of Precision Medicine Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai200125China Department of Dermatology Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200000China

Congenital melanocytic nevi(CMNs)are skin lesions characterized by benign melanocytic proliferations and present at birth or shortly *** and giant CMNs,with a projected adult size≥20 cm and 40 cm in diameter respectively,are more likely to develop into malignant *** most cases,melanoma arising from congenital melanocytic nevus(CMN)is particularly aggressive.

关键词： melanoma congenital melan

Preparation and characteristic study of Schottky diodes based on Ga_(2)O_(3)thin films

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The Journal of China Universities of Posts and Telecommunications 2024年第2期31卷 28-37页

作者： Zhang xuhui Chen Haifeng Liu Xiangtai Lu Qin Wang Zhan Cheng Hang Che Lujie Guan Youyou Han Xiaocong School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'an 710121China

This study uses atomic layer deposition(ALD)to grow Ga_(2)O_(3)films on SiO_(2)substrates and investigates the influence of film thickness and annealing temperature on film *** diode devices are fabricated based on the grown Ga_(2)O_(3)films,and the effects of annealing temperature,electrode size,and electrode spacing on the electrical characteristics of the devices are *** results show that as the film thickness increases,the breakdown voltage of the fabricated devices also increases.A Schottky diode with a thickness of 240 nm can achieve a reverse breakdown voltage of 300 *** film quality significantly improves as the annealing temperature of the film *** a voltage of 5 V,the current of the film annealed at 900℃is 64 times that of the film annealed at 700℃.The optimum annealing temperature for Ohmic contact electrodes is 450℃.At 550℃,the Ohmic contact metal tends to burn,and the performance of the device is *** the electrode spacing increases the forward current of the device but decreases the reverse breakdown *** the Schottky contact electrode size increases the forward current,but the change is not significant,and there is no significant change in the reverse breakdown *** device also performs well at high temperatures,with a reverse breakdown voltage of 220 V at 125℃.

关键词： atomic layer deposition(ALD) Ga_(2)O_(3)film Schottky diode annealing temperature

qSTA2-2,a novel QTL that contributes to seed starch synthesis in Zea mays L.

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Journal of Integrative Agriculture 2024年第4期23卷 1118-1133页

作者： Minghao Cai xuhui Li Zhi Liang Jie Wang Delin Li Zhipeng Yuan Riliang Gu Jianhua Wang Li Li State Key Laboratory of Maize Bio-breeding/Key Laboratory of Crop Heterosis Utilization Ministry of Education/Beijing Innovation Center for Crop Seed Technology/College of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China Institute of Nanfan&Seed Industry Guangdong Academy of ScienceGuangzhou 510316China Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China

The seed storage materials accumulate during seed development,and are essential for seed germination and seedling *** we employed two bi-parental populations of an F2:3 population developed from a cross of improved 220(I220,small seeds with low starch)and PH4CV(large seeds with high starch),as well as recombinant-inbred lines(RILs)of X178(high starch)and its improved introgression line I178(low starch),to identify the genes that control seed storage *** identified a total of 12 QTLs for starch,protein and oil,which explained 3.44-10.79%of the phenotypic *** them,qSTA2-1 identified in F2:3 and qSTA2-2 identified in the RILs partially overlapped at an interval of 7.314-9.554 Mb,and they explained 3.44-10.21%of the starch content variation,so they were selected for further *** mapping of qSTA2-2 with the backcrossed populations of ^(I220)/PH4CV in each generation narrowed it down to a 199.7 kb interval that contains 14 open reading frames(ORFs).Transcriptomic analysis of developing seeds from the near-isogenic lines(NILs)of ^(I220)/PH4CV(BC_(5)F_(2))showed that only 11 ORFs were expressed in 20 days after pollination(DAP)*** of them were upregulated and six of them were downregulated in NIL^(I220),and the differentially expressed genes(DEGs)between NIL^(I220) and NIL^(PH4CV) were enriched in starch metabolism,hormone signal transduction and glycosaminoglycan *** the eleven NIL^(I220) differential expressed ORFs,ORF4(Zm00001d002260)and ORF5(Zm00001d002261)carry 75%protein sequence similarity,both encodes an glycolate oxidase,were the possible candidates of *** analysis and validation indicated that mutation of the qSTA2-2 locus resulted in the dysfunction of ABA accumulation,the embryo/endosperm ratio and the starch and hormone levels.

关键词： QTL mapping seed starch transcriptomic analysis hormone

Hollow FeCoNiAl microspheres with stabilized magnetic properties for microwave absorption

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Nano Research 2024年第3期17卷 2079-2087页

作者： Linhe Yu Gangjie Lian Guozhen Zhu Sue Ren Yanfang Du xuhui Xiong Rui Chen Jincang Zhang Wenbin You Renchao Che Institute of Advanced Materials College of Chemistry and Chemical EngineeringJiangxi Normal UniversityNanchang 330022China Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438China Zhejiang Laboratory Hangzhou 311100China Capital Aerospace Machinery Corporation Limited Beijing 100000China AECC Beijing Institute of Aeronautical Materials Beijing 100095China International Center for Quantum and Molecular Structures Materials Genome InstitutePhysics DepartmentShanghai UniversityShanghai 200444China

Development of high-performance microwave absorption materials(MAM)with stabilized magnetic properties at high temperatures is specifically essential but remains ***,the Snoke's limitation restrains the microwave absorption(MA)property of magnetic *** alloy components is considered an effective way to solve the aforementioned ***,a hollow medium-entropy FeCoNiAl alloy with a stable magnetic property is prepared via simple spray-drying and two-step annealing for efficient *** exhibited an ultrabroad effective absorption band(EAB)of 5.84 GHz(12.16–18 GHz)at a thickness of just 1.6 mm,revealing an excellent absorption ***,the MA mechanism of FeCoNiAl is comprehensively investigated via off-axis ***,the electromagnetic properties,antioxidant properties,and residual magnetism at high temperatures of FeCoNiAl alloys are summarized in detail,providing new insights into the preparation of MAM operating at elevated temperatures.

关键词： microwave absorption hollow structure magnetic stability multiple microwave absorption mechanism

北方地区多能源耦合在集中生活热水系统中的应用

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给水排水 2022年第S2期48卷 42-46页

作者：张军贺鹏鹏周旭辉中国建筑西北设计研究院有限公司西安710018

随着国家双碳目标的控制要求,非传统能源在集中生活热水系统中的应用占比将会越来越大。目前,生活热水系统中非传统热源利用较多的是太阳能、地源热泵、空气源热泵、水源热泵等。太阳能由于受白昼和天气变化的影响,其不稳定性和非连续... 详细信息

随着国家双碳目标的控制要求,非传统能源在集中生活热水系统中的应用占比将会越来越大。目前,生活热水系统中非传统热源利用较多的是太阳能、地源热泵、空气源热泵、水源热泵等。太阳能由于受白昼和天气变化的影响,其不稳定性和非连续性一直是其被很好利用的一个制约因素。设置有集中生活热水系统的工程,若采用太阳能热源就必须设置相应的辅助热源,辅助热源是保障系统稳定的最重要屏障。但从经济性而言太阳能又是其他几种非传统能源所无法比拟的,随着节能要求的进一步提高,采用集中非传统能源和传统能源的组合,在一段时间内势必是北方地区集中生活热水系统的能源利用的一种主流。高效的利用好非传统能源、传统能源的组合,使其系统高效耦合,才能真正达到系统的最大化节能、稳定、安全和可靠。

关键词：太阳能空气源城市热网高效耦合

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重动句内部结构及意义初探

楚雄师范学院学报 2014年第1期29卷 34-37页

作者：周旭慧西南交通大学四川成都611756

重动句是汉语中颇具特色的句式,历来学者对其研究很多,对重动句进行初步的分类,并将重动句与其他句式进行对比,进而对重动句的独特价值进行分析阐释。

关键词：重动句补语结构价值

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线粒体对间充质干细胞成骨分化功能的研究

中国骨质疏松杂志 2023年第4期29卷 573-577页

作者：胡淼孟怡辰周许辉海军军医大学长征医院骨科上海200003

间充质干细胞成骨分化能力异常减弱和成骨细胞数量异常下降都会导致生物体内骨代谢紊乱,诱导骨质疏松症的发生。线粒体在MSC多能性保持和成骨分化过程中具有十分重要的作用,通过能量代谢、抗氧化途径、代谢相关信号通路、线粒体生物发... 详细信息

间充质干细胞成骨分化能力异常减弱和成骨细胞数量异常下降都会导致生物体内骨代谢紊乱,诱导骨质疏松症的发生。线粒体在MSC多能性保持和成骨分化过程中具有十分重要的作用,通过能量代谢、抗氧化途径、代谢相关信号通路、线粒体生物发生、线粒体动力学和线粒体自噬等参与间充质干细胞成骨分化的调控,形成了复杂的调节网络。本文综述了MSC成骨分化中线粒体的重要功能和作用,以及部分通过调节线粒体功能发挥抗骨质疏松治疗的药物,为进一步探讨间充质干细胞成骨分化功能失调的机制提供新的思路,为临床治疗骨质疏松症提供新的靶点。

关键词：线粒体间充质干细胞成骨细胞成骨分化

湿陷性黄土地区室外检漏井和检漏管沟设置探讨

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给水排水 2022年第5期48卷 115-118,124页

作者：张军石敏娜周旭辉中国建筑西北设计研究院有限公司西安710018

在湿陷性黄土地区,常规方法设置检漏井及检漏管沟容易造成建筑物外检查井数量过多,严重影响室外的景观效果.且不利于工程项目日常维护管理。因此,需寻求更加科学合理的设置方式来满足规范规定和室外景观的需求。对检漏井常规做法、局部... 详细信息

在湿陷性黄土地区,常规方法设置检漏井及检漏管沟容易造成建筑物外检查井数量过多,严重影响室外的景观效果.且不利于工程项目日常维护管理。因此,需寻求更加科学合理的设置方式来满足规范规定和室外景观的需求。对检漏井常规做法、局部集中式检漏井设置和其他新型检漏方式进行综合比较,指出湿陷性黄土地区室外检漏井及检漏管沟的设置和建筑物分类、场地湿陷性类型、地基湿陷等级以及地基处理后下部未处理湿陷性黄土层的剩余湿陷量密切相关,结合湿陷性黄土地区建筑经验和施工条件等因素设置室外检漏井和检漏管沟对于整个工程项目的安全性和美观性起至关重要的作用。

关键词：湿陷性黄土地区检漏管沟检漏井局部集中式检漏井

滑道不平顺对多点支承斜拉桥转体系统受力和稳定性影响研究

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施工技术（中英文） 2023年第7期52卷 122-127页

作者：周旭辉中铁十一局集团有限公司湖北武汉430031

跨襄阳北编组站为齿轮齿轨式多点支承转体斜拉桥,滑道的平顺性是多点支承转体施工的重要因素之一,为研究滑道不平顺对多点支承转体系统受力和转动稳定性的影响,通过大比例转体模型试验,探讨了滑道不平顺对承力支腿应力、球铰应力、转动... 详细信息

跨襄阳北编组站为齿轮齿轨式多点支承转体斜拉桥,滑道的平顺性是多点支承转体施工的重要因素之一,为研究滑道不平顺对多点支承转体系统受力和转动稳定性的影响,通过大比例转体模型试验,探讨了滑道不平顺对承力支腿应力、球铰应力、转动牵引力、主梁位移和扭转的影响。研究结果表明:随着滑道不平顺度的增大,应力变化规律基本不发生改变,而承力支腿的应力变化率随之增大,桥梁转动稳定性逐渐降低;当承力支腿经过不平顺滑道时,上、下球铰应力变化率基本在±5%范围内发生波动,球铰应力受滑道不平顺影响较小;随着滑道不平顺度的增大,转动所需的牵引力和主梁竖向幅值逐渐增大,而滑道不平顺对主梁扭转和主梁应力影响较小。

关键词：桥梁工程斜拉桥多点支承转体系统平顺度受力特性稳定性