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Influence of Annealing on the Grain Growth and Thermal Diffusivity of Nanostructured YSZ Thermal Barrier Coating

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Journal of Materials Science & Technology 2006年第6期22卷 793-797页

作者： Na WANG Chungen zhou Shengkai gong Huibin XU Department of Materials Science and Engineering Beijing University of Aeronautics and Astronautics Beijing 100083 China

The nanostructured zirconia coatings were deposited by atmospherically plasma spraying. Scanning electron microscopy （SEM）, transmission electron microscopy （TEM） and X-ray diffraction were used to investigate the microstructure of the zirconia coatings. Thermal diffusivity values at normal temperatures have been evaluated by laser flash technique. Effect of annealing on the microstructure evolution of the zirconia coating has been performed. The grains and thermal diffusivity are increased with increasing annealing time and temperature. The grain growth is according to the GRIGC （the grain rotation induced grain coalescence） mechanism. The increase in thermal diffusivity is attributed to the grain growth and the decrease in porosity of nanostructured zirconia coatings.

关键词： Grain size Thermal diffusivity Thermal barrier coating Plasma spraying

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教育服务多元发展——周功鑫院长专访

东南文化 2010年第3期 13-17页

作者：周功鑫龚良台北故宫博物院南京博物院江苏南京210016

2009年10月,南京博物院龚良院长受邀访问台北故宫博物院,并接受本刊编委会委托,就博物馆的展览、教育、公众服务、藏品数字化、博物馆产业等,对周功鑫院长进行了专访。周功鑫院长认为,博物馆应履行教育职能,将教育视为展览最大目的,依... 详细信息

2009年10月,南京博物院龚良院长受邀访问台北故宫博物院,并接受本刊编委会委托,就博物馆的展览、教育、公众服务、藏品数字化、博物馆产业等,对周功鑫院长进行了专访。周功鑫院长认为,博物馆应履行教育职能,将教育视为展览最大目的,依据观众需求设计教育活动,藉此为民众服务;同时,利用现代科技,加强典藏数字化建设,推动文化创意产业,致力多元发展,促进文化交流,提升整体服务品质,从而将博物馆建设成为民众愿意亲近并经常光顾之处。

关键词：教育服务多元发展周功鑫

Identification of a novel caspase cleavage motif AEAD

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Virologica Sinica 2024年第5期39卷 755-766页

作者： Yujie Fang zhou gong Miaomiao You Ke Peng State Key Laboratory of Virology Center for Antiviral ResearchCenter for Biosafety Mega-ScienceWuhan Institute of VirologyChinese Academy of SciencesWuhan430207China University of Chinese Academy of Sciences Beijing100049China State Key Laboratory of Magnetic Resonance and Atomic Molecular Physics Innovation Academy for Precision Measurement Science and Technology Chinese Academy of SciencesWuhan430071China Provincial Key Laboratory of Jiangxia Wuhan430207China

Infections of many viruses induce caspase activation to regulate multiple cellular pathways,including programmed cell death,immune signaling and *** of caspase cleavage sites and substrates are important for understanding the regulation mechanisms of caspase ***,we identified and analyzed a novel caspase cleavage motif AEAD,and confirmed its caspase dependent cleavage activity in natural substrate,such as nitric oxide-associated protein 1(NOA1).Fusing the enhanced green fluorescent protein(EGFP)with the mitochondrial marker protein Tom20 through the AEAD motif peptide localized EGFP to the *** the activation of caspase triggered by Sendai virus(SeV)or herpes simplex virus type 1(HSV-1)infection,EGFP diffusely localized to the cell due to the caspase-mediated cleavage,thus allowing visual detection of the virusinduced caspase *** AEAD peptide-derived inhibitor Z-AEAD-FMK were developed,which significantly inhibited the activities of caspases-1,-3,-6,-7,-8 and-9,exhibiting a broad caspase inhibition *** inhibitor further prevented caspases-mediated cleavage of downstream substrates,including BID,PARP1,LMNA,pro-IL-1β,pro-IL-18,GSDMD and GSDME,protecting cells from virus-induced apoptotic and pyroptotic cell ***,our findings provide a new perspective for the identification of novel caspase cleavage motifs and the development of new caspase inhibitors and anti-inflammatory drugs.

关键词： Caspase AEAD motif Inhibitor Virus Cell death

Estimation and test of restricted linear EV model with nonignorable missing covariates

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Applied Mathematics(A Journal of Chinese Universities) 2018年第3期33卷 344-358页

作者： TANG Lin-jun ZHENG Sheng-chao zhou Zhan-gong Department of Statistics Jiaxing University

This paper deals with estimation and test procedures for restricted linear errors-invariables(EV) models with nonignorable missing covariates. We develop a restricted weighted corrected least squares(WCLS) estimator based on the propensity score, which is fitted by an exponentially tilted likelihood method. The limiting distributions of the proposed estimators are discussed when tilted parameter is known or unknown. To test the validity of the constraints,we construct two test procedures based on corrected residual sum of squares and empirical likelihood method and derive their asymptotic properties. Numerical studies are conducted to examine the finite sample performance of our proposed methods.

关键词： errors-in-variables model nonignorable missing data propensity score smoothed empirical likelihood

Solvent-assisted polymer micro-molding

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Chinese Science Bulletin 2009年第13期54卷 2193-2204页

作者： HAN LuLu zhou Jing gong Xiao GAO ChangYou Department of Polymer Science and Engineering Zhejiang University Hangzhou 310027 China

The micro-molding technology has played an important role in fabrication of polymer micro-patterns and development of functional *** such a process,suitable solvent can swell or dissolve the polymer films to decrease their glass transition temperature(Tg) and viscosity and thereby improve flowing ***,it is easy to obtain the 2D and 3D patterns with high fidelity by the solvent-assisted *** with the high temperature molding,this technology overcomes some shortcomings such as shrinking after cooling,degradation at high temperature,difficulty in processing some functional materials having high Tg,*** can be applied to making patterns not only on polymer monolayers but also on polyelectrolyte ***,the compression-induced patterns on the multilayers are chemically homogenous but physically *** this review,the controlling factors on the pattern quality are also discussed,including materials of the mold,solvent,pressure,temperature and pattern density.

关键词：聚合物膜微成型溶剂玻璃化转变温度聚电解质多层膜成型技术功能材料功能器件

Deciphering In-vivo Cross-linking Mass Spectrometry Data for Dynamic Protein Structure Analysis

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Chemical Research in Chinese Universities 2022年第3期38卷 758-762页

作者： ZHAO Lili gong zhou ZHAO Qun ZHANG Lihua ZHANG Yukui CAS Key Laboratory of Separation Science for Analytical Chemistry National Chromatographic R.&A.CenterDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian116023P.R.China University of Chinese Academy of Sciences Beijing100039P.R.China Innovation Academy for Precision Measurement Science and Technology Chinese Academy of SciencesWuhan430071P.R.China

Protein structure and protein-protein interactions(PPIs)are crucial for regulating cellular activities required for cell viability and *** cross-linking coupled with mass spectrometry(CXMS)has become a versatile tool providing insights into both protein structure with distance restraints and protein-protein interactions with interface ***-links as the most information-rich data in a CXMS experiment are responsible for the structural model validation and integrative modeling with high throughput and *** this work,ensemble refinement of the existing protein structure against the in-vivo cross-linking distance restraints was performed for dynamic protein structure modeling and protein interaction binding interface building in the intracellular *** results indicate great potential of in-vivo CXMS data for providing a molecular basis of protein structural dynamics exploration and function performance.

关键词： In-vivo chemical cross-linking Cross-linking distance restraint Ensemble refinement Structural dynamics Disorder region

Effect of cement on the stabilization of loess

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Journal of Mountain Science 2017年第11期14卷 2325-2336页

作者： ZHANG Chong-lei JIANG Guan-lu SU Li-jun zhou gong-dan Key Laboratory of Mountain Hazards and Earth Surface Processes Institute of Mountain Hazards and Environment Chinese Academy of Sciences Key Laboratory of High-speed Railway Engineering of Ministry of Education School of Civil Engineering Southwest Jiaotong University CAS Center for Excellence in Tibetan Plateau Earth Sciences University of Chinese Academy of Sciences

Considering the potential use of cementstabilized loess(CSL) as a construction material for structures that are subjected to frequent loess landslides, this paper explores the stabilization and improvement of geotechnical characteristics of loess achieved by the addition of 0%-9% cement by dry weight. Laboratory evaluations investigated the consistency limits, compaction, compressibility, California bearing ratio(CBR), direct shear strength, and unconfined compression strength(UCS) of CSL for different curing stages. A durability index was quantified to estimate the influence of wetting-drying(w-d) cycles on CSL strength, and an optimum cement dosage was also identified. The results reveal that the cohesion of CSL is substantially more sensitive to structure than its friction angle and that cohesion is responsible for shear strength increase after remoulding. The cement proportions have an effective role in the enhancement of compressibility. The development of UCS can be categorized into the early stage(14 days). The increase in strength primarily occurred in the first 14 days. The w-d cycles have a significantinfluence on the decrease in compression strength. The CBR value increases with increments of additional proportions and compaction times. The relationships of UCS versus the compressibility modulus and UCS versus CBR are established to facilitate the mix design for strength. A rational predictive exponential equation is proposed to predict the durability index for different w-d cycles.

关键词： Landslide Cement Loess stabilization Durability index Wetting-drying cycle

Oxidation and thermal fatigue of EB-PVD thermal barrier coatings on tube superalloy substrate

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中国有色金属学会会刊：英文版 2006年第A02期16卷 10-13页

作者： GAO Yu ZHANG Chun-xia zhou Chun-gen gong Sheng-kai XU Hui-bin Department of Materials Science and Engineering B eijing University of Aeronautics and Astronautics Beijing 100083 China

Two-layer structured thermal barrier coatings (TBCs) (NiCoCrAlY (bond coat)+(6%-8%, mass fraction) Y2O3-stabilized ZrO2(YSZ top coat)) were deposited by electron beam physical vapor deposition (EB-PVD) on tube superalloy substrates. The samples were investigated by isothermal oxidation and thermal shock tests. It is found that the mass gains of the,substrate with and 2 without TBCs are 0.165 and 7.34 mg/cm(2), respectively. So the TBCs system is a suitable protection for the substrate. In thermal shock tests the vertical cracks initiate at the top coat and grow into the bond coat, causing the oxidation of the bond coat along the cracks. Failure of the TBCs system occurs by the spallation of the YSZ from the bond coat, and some micro-cracks are found at the location where the fragment of the YSZ top coat spalled from.

关键词：超耐热合金管状基质 EB-PVD 电子束物理汽相淀积氧化热冲击热障涂层热疲劳

Comparison of Rheometric Devices for Measuring the Rheological Parameters of Debris Flow Slurry

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Journal of Mountain Science 2015年第5期12卷 1125-1134页

作者： YANG Hong-juan WEI Fang-qiang HU Kai-heng zhou gong-dan LYU Juan Key Laboratory of Mountain Hazards and Earth Surface Process Chinese Academy of Sciences Institute of Mountain Hazards and Environment Chinese Academy of Sciences

Soil samples with clay content ranging from 15% to 31%, were taken from three debris flow gullies in Southwest China. Three debris flow slurry samples were prepared and tested with four measuring systems of an Anton Paar Physica MCR301 rheometer, including the concentric cylinder system,the parallel-plate system, the vane geometry, and the ball measuring system. All systems were smoothwalled. Flow curves were plotted and yield stress was determined using the Herschel-Bulkley model,showing differences among the different *** curves from the concentric cylinder and parallelplate systems involved two distinct regions, the low shear and the high shear regions. Yield stresses determined by data fitting in the low shear region were significantly lower than the values from the inclined channel test which is a practical method for determining yield stress. Flow curves in the high shear region are close to those from the vane geometry and the ball measuring system. The fitted values of yield stress are comparable to the values from the inclined channel test. The differences are caused by wall-slip effects in the low shear *** geometry can capture the stress overshoot phenomenon caused by the destruction of slurry structure, whereas end effects should be considered in the determination of yield stress. The ball measuring system can give reasonable results, and it is applicable for rheological testing of debris flow slurries.

关键词： Debris flow Slurry Rheometer Concentric cylinder system Parallel plate system Vane Ball measuring system