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Circle of Friends

China Today 2025年第1期74卷 32-35页

作者： zhou lin 不详

CISCE brings together partners on the global industrial chain to collaborate and enhance global *** in South Yorkshire in north-central England,British Steel,originally founded in 1967,is the U.K.’s only manufacturer of *** now produces three million tons of crude steel annually and has the distinction of maintaining stable production even during the COVID-19 pandemic,with its ironmaking,steelmaking and all rolling mills in full operation.

关键词： annually partner CISC

An Ancient Civilization and Its Exploration in Modernization

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China Today 2025年第1期74卷 65-65页

作者： zhou lin 不详

Modernization has been a common issue in the development of all countries since the 20th ***,as the global modernization movement developed,different countries and regions diverged in their modernization paths and *** A New Path Ahead:Chinese Modernization,the author Dai Mucai,an expert in theoretical research on the Chinese path to modernization and a professor at the School of Marxism of Tsinghua University,elaborates on why the Chinese path to modernization is unprecedented in history,its originality and unique features,what it means to the world,and how to build a socialist modernization in a country with a 5,000-year-old civilization.

关键词： modernization Ancient Modernization

Measurement of Local Gravity via a Cold Atom Interferometer

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Chinese Physics Letters 2011年第1期28卷 78-81页

作者： zhou lin State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics Wuhan 430071 Center for Cold Atom Physics Chinese Academy of Sciences Wuhan 430071 Graduate University of the Chinese Academy of Sciences Beijing 100049

We demonstrate a precision measurement of local gravity acceleration 9 in Wuhan by a compact cold atom interferometer. The atom interferometer is in vertical Mach-Zehnder configuration realized using a 7r /2 - π - π /2 Raman pulse sequence. Cold atoms were prepared in a magneto-optical trap, launched upward to form an atom fountain, and then coherently manipulated to interfere by stimulated Raman transition. Population signal vs Raman laser phase was recorded as interference fringes, and the local gravity was deduced from the interference signal. We have obtained a resolution of 7 × 10-9g after an integration time of 236s under the best vibrational environment conditions. The absolute g value was derived from the chirp rate with a difference of 1.5 × 10--07 g compared to the gravity reference value. The tidal phenomenon was observed by continuously monitoring the local gravity over 123 h.

关键词： Atomic and molecular physics Quantum gases liquids and solids Optics quantum optics and lasers

不同策略提高间充质干细胞治疗肝纤维化:效果与潜在风险分析

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中国组织工程研究 2025年第23期29卷 5002-5012页

作者：徐岩王雪淞周林周晓磊金煜叶俊松赣南医科大学第一附属医院干细胞临床转化分中心江西省赣州市341000 赣南医科大学康复学院江西省赣州市341000 赣州市干细胞与再生医学重点实验室江西省赣州市341000 组织工程江西省重点实验室江西省赣州市341000 心脑血管疾病防治教育部重点实验室江西省赣州市341000

背景:目前大量研究表明,间充质干细胞联合不同治疗策略能更有效地改善肝纤维化,抑制其向终末期肝病发展。目的:探讨间充质干细胞联合不同策略改善肝纤维化疗效优于单独间充质干细胞治疗的相关机制。方法:由第一作者应用计算机在中国知... 详细信息

背景:目前大量研究表明,间充质干细胞联合不同治疗策略能更有效地改善肝纤维化,抑制其向终末期肝病发展。目的:探讨间充质干细胞联合不同策略改善肝纤维化疗效优于单独间充质干细胞治疗的相关机制。方法:由第一作者应用计算机在中国知网、万方、维普、PubMed、Web of Science和Nature数据库中检索涉及间充质干细胞联合不同策略改善肝纤维化的研究,中文检索词为“间充质干细胞,肝纤维化,联合治疗,肝星状细胞”,英文检索词为“mesenchymal stem/stromal cells,liver/hepatic fibrosis/cirrhosis,combination therapy,hepatic stellate cells/HSCs”,通过快速浏览文章题目及摘要进行筛选,排除与主题关系不密切的文章,最终筛选出104篇文献进行综述分析。结果与结论:间充质干细胞通过分化为肝样细胞、抑制肝星状细胞活化、免疫调节等机制来改善肝纤维化,但间充质干细胞移植后肝脏定植率低、存活率低、作用时间短等原因限制了其临床应用。间充质干细胞联合药物、基因修饰、细胞因子等多种治疗策略改善肝纤维化的疗效优于间充质干细胞单独治疗,并且间充质干细胞联合不同策略通过促进间充质干细胞归巢、抑制肝星状细胞活化、调节微环境、调控信号通路等机制更有效地改善肝纤维化。间充质干细胞还可以通过预处理、miRNA调控及与其他细胞联合,使间充质干细胞在减轻肝纤维化方面表现出更好的肝源性分化、归巢和存活功能。间充质干细胞联合不同策略并不能规避间充质干细胞单独治疗肝纤维化的潜在风险,而且这些策略(药物、基因修饰和细胞因子等)自身安全性也值得考虑。此外,间充质干细胞移植数量和途径等有待进一步研究。

关键词：间充质干细胞肝纤维化肝星状细胞信号通路联合用药基因修饰归巢微RNA

Systematic diesel molecular performance evaluation based on quantitative structure-property relationship model

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Petroleum Science 2022年第2期19卷 809-818页

作者： Guang-Qing Cai lin-zhou Zhang State Key Laboratory of Heavy Oil Processing Petroleum Molecular Engineering Center(PMEC)China University of PetroleumBeijing 102249China

The production and separation of optimal molecules in diesel fuels require a systematic property evaluation for the containing *** paper evaluates the diesel molecules based on four key quality indicators:low-temperature fluidity,cleanliness,ignition,and power *** established the corresponding quantitative structure-property relationship models for corresponding properties,which are freezing point,yield sooting index,cetane number,and combustion *** models were applied for the screening of the high-performance molecules that is suitable for *** molecular performance distribution of the conventional diesel and biodiesel were also ***,we analyzed the effect of different transformation paths on molecular properties,giving guidance on the conversion process design.

关键词： Diesel Optimal molecules QSPR Molecular screening

Chemical Intervention on Staphylococcus aureus Virulence

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Chinese Journal of Chemistry 2019年第2期37卷 183-193页

作者： lin-lin zhou Cai-Guang Yang State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of the Chinese Academy of Sciences Beijing 100049China

Resistance to conventional antibiotics has raised worldwide attention. Notably, Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most life-threatening health concerns. Although effective against bacterial infections, conventional antibiotics have also showed a series of side effects such as gut microbiota imbalance.

关键词： Chemical Intervention Staphylococcus aureus Virulence

An approach for choosing discretization schemes and grid size based on the convection-diffusion equation

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Applied Mathematics and Mechanics(English Edition) 2018年第6期39卷 877-890页

作者： lin zhou Zhenghong GAO Yuan GAO School of Aeronautics Northwestern Polytechnical University

A new approach for selecting proper discretization schemes and grid size is presented. This method is based on the convection-diffusion equation and can provide insight for the Navier-Stokes equation. The approach mainly addresses two aspects, i.e., the practical accuracy of diffusion term discretization and the behavior of high wavenum- ber disturbances. Two criteria are included in this approach. First, numerical diffusion should not affect the theoretical diffusion accuracy near the length scales of interest. This is achieved by requiring numerical diffusion to be smaller than the diffusion discretization error. Second, high wavenumber modes that *** smaller than the length scales of interest should not be amplified. These two criteria provide a range of suitable scheme combinations for convective flux and diffusive flux and an ideal interval for grid spacing. The effects of time discretization on these criteria are briefly discussed.

关键词： convection-diffusion equation cell ReynOlds number diffusion term accu-racy high wavenumber mode scheme selection

How Can Machine Learning and Optimization Help Each Other Better?

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Journal of the Operations Research Society of China 2020年第2期8卷 341-351页

作者： zhou-Chen lin Key Laboratory of Machine Perception School of Electronics Engineering and Computer SciencePeking UniversityBeijing 100871China

Optimization is an indispensable part of machine learning as machine learning needs to solve mathematical models *** the other hand,machine learning can also provide new momenta and new ideas for *** paper aims at inv... 详细信息

关键词： Optimization Machine learning Generalization ability Data

Determining proportions of lunar crater populations by fitting crater size distribution

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Research in Astronomy and Astrophysics 2016年第12期16卷 51-58页

作者： Nan Wang Ji-lin zhou School of Astronomy and Space Science & Key Laboratory of Modern Astronomy and Astrophysics in Ministry of Education Nanjing University

We determine the proportions of two mixed crater populations distinguishable by size distributions on the Moon. A ＂multiple power-law＂ model is built to formulate crater size distribution N（D） ∝ D-αwhose slope α varies with crater diameter D. This model is then used to fit size distributions of lunar highland craters and Class 1 craters. The former is characterized by α = 1.17 ± 0.04, 1.88 ± 0.07,3.17 ± 0.10 and 1.40 ± 0.15 for D ranges ~ 10- 49, 49- 120, 120- 251 and ~ 251- 2500 km, while the latter has a single slope α = 1.96 ± 0.14 for about 10- 100 km. They are considered as Population 1 and2 crater size distributions, whose sum is then fitted to the global size distribution of lunar craters with D between 10 and 100 km. Estimated crater densities of Population 1 and 2 are 44 × 10-5and 5 × 10-5km-2respectively, leading to the proportion of the latter being 10%. This result underlines the need for more thoroughly investigating Population 1 craters and their related impactors, the primordial main-belt asteroids, which dominated the late heavy bombardment.

关键词： planets and satellites: surfaces -- Moon -- minor planets asteroids: general