检索结果-南通市图书馆

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting qiu Na Li Zhengxiang Zhou Ru Ye Liyan zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

某双链季铵盐消毒液在低温下对物体表面的杀菌效果观察

在线全文

学校读者我要写书评

暂无评论

中国消毒学杂志 2024年第7期41卷 489-491页

作者：钟秋彤张显勇谭俊杰邱智华何威叶俊豪广州市微生物研究所有限公司广东广州510663

目的观察一种双链季铵盐消毒液在-40℃低温环境中的消毒效果,为低温消毒应用提供参考。方法采用载体定量杀菌试验和现场消毒试验方法,对该双链季铵盐消毒液在低温条件下环境表面消毒效果进行观察。结果该双链季铵盐消毒液原液含量为37 g... 详细信息

目的观察一种双链季铵盐消毒液在-40℃低温环境中的消毒效果,为低温消毒应用提供参考。方法采用载体定量杀菌试验和现场消毒试验方法,对该双链季铵盐消毒液在低温条件下环境表面消毒效果进行观察。结果该双链季铵盐消毒液原液含量为37 g/L,pH值为5.03。该消毒液在-40℃下放置>8 h后无析出,无结晶。在-40℃低温冷库中,原液喷洒作用30 min,对织物样片上大肠埃希菌和金黄色葡萄球菌的杀灭对数值均>3.00;原液按10 mL/m^(3)喷雾作用60 min,对玻璃表面的大肠埃希菌和金黄色葡萄球菌杀灭对数值均>3.00。该消毒液原液对新西兰兔完整皮肤无刺激性,对小鼠急性经口毒性试验为无毒级,对小鼠无致微核作用。结论该双链季铵盐消毒液在-40℃低温下可杀灭环境表面大肠埃希菌和金黄色葡萄球菌,属于实际无毒物质。

关键词：双链季铵盐低温消毒剂物体表面消毒效果

In vivo 3-photon fluorescence microscopy of white matter in mouse brain excited at the 1700 nm window

在线全文

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2024年第5期17卷 81-87页

作者： Jie Huang Jincheng zhong Shen tong Yingxian Zhang Ping qiu Ke Wang Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060P.R.China School of Medical Information and Engineering Xuzhou Medical UniversityXuzhou 221004P.R.China

White matter,a densely packed collection of myelinated axons,plays an essential part in neural *** high spatial resolution and deep penetration,multi-photon microscopy(MPM)is promising for white matter imaging in animal models in *** third harmonic generation(THG)signal can be generated from white matter,but the bottom part of the white matter layer generates weak THG due to its high ***,we demonstrate an in vivo labeling and imaging technology,capable of visualizing the white matter layer in the mouse brain,combining°uorescence labeling with MitoTracker Red and three-photon°uorescence(3PF)microscopy excited at the 1700 nm window.3PF signals are several times higher than THG signals,resulting in deeper imaging of the white matter layer with the *** results indicate that 3PF microscopy is a promising technology for white matter imaging in the deep brain in vivo.

关键词： Three-photon microscopy white matter myelin MitoTracker Red

Full-duplex two-way AF relaying systems with imperfect interference cancellation in Nakagami-m fading channels

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2021年第8期64卷 143-155页

作者： Jianping tong Caijun zhong College of Science Zhejiang University of Technology Department of Information and Communication Engineering Zhejiang University

Full-duplex(FD) two-way relaying has the potential to substantially improve the spectral efficiency of the system, and is regarded as an enabling technology for the next generation wireless communication systems. Nevertheless, the joint effect of residual interference and channel fading condition on the fundamental performance of FD two-way relaying systems remains unclear. Motivated by this, this study considers a general FD two-way amplify-and-forward(AF) relaying system with imperfect interference cancellation in the versatile Nakagami-m fading channels, and presents a detailed analytical investigation on the outage performance of the system. The findings of the paper suggest that the performance of the FD two-way AF relaying system depends heavily on the residual interference strength, fading condition parameter m, and signal-to-noise ratio(SNR). The FD scheme outperforms the half-duplex(HD) two-way relaying counterpart in the low and moderate SNR regime, while becomes inferior in the high SNR regime, owing to strong residual interference. Also, compared to the channel fading condition of the information transmission channels, the impact of the channel fading condition of the interference channel on the system performance is relatively insignificant. Moreover, it is desirable to deploy the FD scheme when the channel fading condition of the information transmission channels is good, since it can effectively alleviate the detrimental effect of residual interference.

关键词： full-duplex two-way relaying Nakagami-m fading outage probability sum throughput

同方期刊数据库

An intelligent SVM modeling process for crude oil properties prediction based on a hybrid GA-PSO method

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2019年第8期27卷 1888-1894页

作者： Kexin Bi tong qiu Department of Chemical Engineering Tsinghua UniversityBeijing 100084China Beijing Key Laboratory of Industrial Big Data System and Application Beijing 100084China

Properties prediction of crude oil remains an essential issue for refineries. In this communication, an exhaustive and extendable support vector machine(SVM) intelligent prediction process has been proposed to solve this problem. A novel hybrid genetic algorithm-particle swarm optimization(GA-PSO)method was applied to optimize the SVM model. The optimization process and result demonstrated that the newly proposed GA-PSO-SVM method was more accurate and time-saving than the classical GA or PSO method. Compared with the classical Grid-search SVM, the combined GA-PSO-SVM model appeared to be more applicable for the properties prediction task. The TBP distillation curve fitting was exampled to evaluate the performance of the developed model. The regression result demonstrated the high accuracy and efficiency of the proposed process. The model can be applied in the Industrial Internet as a plugin, and the adaptability and flexibility is demonstrated by the implement of crude oil molecular reconstruction employing the intelligent prediction process.

关键词： Intelligent properties prediction Support vector machine Hybrid GA-PSO TBP distillation curve fitting

Logarithm-transform piecewise linearization method for the optimization of fasoline blending processes

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2018年第8期26卷 1684-1691页

作者： Yu Li tong qiu Department of Chemical Engineering Tsinghua University

Gasoline blending is a key process in a petroleum refinery, as it can yield 60%–70% of a typical refinery's total revenue. This process not only exhibits non-convex nonlinear blending behavior due to the complicated blend mechanism of various component feedstocks with different quality properties, but also involves global optimum searching among numerous blending recipes. Since blend products are required to meet a series of quality requirements and highly-sensitive to the proportion changes of blending feedstocks, global optimization methods for NLP problems are often difficult to be applied because of heavy computational burdens. Thus, piecewise linearization methods are naturally proposed to provide an approximate global optimum solution by adding binary variables into the models and converting the original NLP problems into MILP ones. In this paper, Logarithmtransform piecewise linearization(LTPL) method, an improved piecewise linearization, is proposed. In this method a logarithm transform is applied to convert multi-variable multi-degree constraints into a series of single-variable constraints. As a result, the number of 0–1 variables is greatly reduced. In the final part of this paper, an industrial case study is conducted to demonstrate the effectiveness of LTPL method. In principle, this method would be useful for blending problems with complicated empirical or theoretical models.

关键词： Piecewise linearization Blending Non-convex Global optimization

Corrosion behavior of three Ag–50Cu alloys prepared by different processes in NaCl solutions

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2017年第1期36卷 61-68页

作者： zhong-qiu Jia qiu-Ying Liang qiu-Yue Tian zhong-qiu Cao Yan Wang College of Chemistry-and Chemical Engineering Shenyang Normal University Shenyang 110034 China

Corrosion behavior of two nanocrystalline bulk Ag–50Cu alloys and one coarse-grained counterpart prepared by liquid-phase reduction(LPR), mechanical alloying(MA) and powder metallurgy(PM) methods,respectively, were investigated in Na Cl solutions. They were finished by means of PARM273 A and M5210 electrochemical apparatus through potentiodynamic polarization method and electrochemical impedance spectroscopy(EIS) technique. The results show that corrosion rates of three Ag–50Cu alloys increase with the increment of Na Cl solution concentrations. Corrosion rates of LPRAg–50Cu alloy are a little higher than those of PMAg–50Cu alloy,but evidently lower than those of MAAg–50Cu alloy. The difference in corrosion rates is attributed to the large reduction in the grain size and homogeneous microstructure of nanocrystalline alloys. Passive current densities decrease and afterward increase for PMAg–50Cu alloy,decrease for MAAg–50Cu alloy, and increase for LPRAg–50Cu alloy with the increment of Na Cl solution concentrations. After the grain sizes are refined, passive current densities become lower.

关键词： Copper alloys Corrosion Corrosion rate Corrosive effects Electrochemical corrosion Electrochemical impedance spectroscopy Electrochemistry Grain size and shape Mechanical alloying Nanocrystals Powder metallurgy Reduction Silver Silver alloys

Data-driven intelligent modeling framework for the steam cracking process

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2023年第9期61卷 237-247页

作者： Qiming Zhao Kexin Bi tong qiu Department of Chemical Engineering Tsinghua UniversityBeijing 100084China Beijing Key Laboratory of Industrial Big Data Systems and Applications Tsinghua UniversityBeijing 100084China School of Chemical Engineering Sichuan UniversitySichuan 610065China Department of Bioprocess Engineering Institute of BiotechnologyTechnische Universität BerlinBerlin 10623Germany

Steam cracking is the dominant technology for producing light olefins,which are believed to be the foundation of the chemical *** models of the cracking process can boost production efficiency and profit *** advancements in machine learning research have recently enabled data-driven solutions to usher in a new era of process ***,its practical application to steam cracking is still hindered by the trade-off between prediction accuracy and computational *** research presents a framework for data-driven intelligent modeling of the steam cracking *** data preparation and feature engineering techniques provide computational-ready datasets for the framework,and feedstock similarities are exploited using k-means *** propose LArge-Residuals-Deletion Multivariate Adaptive Regression Spline(LARD-MARS),a modeling approach that explicitly generates output formulas and eliminates potentially outlying *** framework is validated further by the presentation of clustering results,the explanation of variable importance,and the testing and comparison of model performance.

关键词： Mathematical modeling Data-driven modeling Process systems Steam cracking Clustering Multivariate adaptive regression spline

Enantioselective reductive conjugate alkenylation of α,β-enones with keto alkenyl acetates by nickel catalysis

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期 157-162页

作者： Rong-De He Yun-Lei Luo qiu-Quan Pan Qi-Wei Yao Xing-zhong Shu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University

Reactions involving alkenyl acetates offer cost-effective and environmentally friendly routes for alkene synthesis, yet their asymmetric variant remains elusive. Concurrently, asymmetric conjugate alkenylation predominantly centered on nucleophilic addition using alkenyl–M. This manuscript presents an asymmetric reductive conjugate alkenylation reaction involving alkenyl acetates. The method facilitates the enantioselective addition of keto alkenyl groups to α,β-enones, resulting in the formation of unsaturated diketones—a class of useful structural motifs that are challenging to access otherwise. The use of electron-rich Pyroxy ligand is essential for achieving both high reaction efficiency and enantioselectivity.

关键词：