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Gene expression,transcription factor binding and histone modification predict leaf adaxial-abaxial polarity related genes

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Horticultural Plant Journal 2024年第4期10卷 971-982页

作者： Wei Sun Zhicheng zhang Guusje Bonnema Xiaowu Wang Aalt Dirk Jan van Dijk State Key Laboratory of Vegetable Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China Sino-Dutch Joint Lab of Vegetable Genomics Beijing 100081China Bioinformatics Group Wageningen University and Research6708 PB Wageningenthe Netherlands Plant Breeding Wageningen University and Research6708 PB Wageningenthe Netherlands Biosystems Data Analysis Swammerdam Institute for Life SciencesUniversity of Amsterdam1090 GE Amsterdamthe Netherlands

Leaf adaxial-abaxial(ad-abaxial)polarity is crucial for leaf morphology and function,but the genetic machinery governing this process remains *** uncover critical genes involved in leaf ad-abaxial patterning,we applied a combination of in silico prediction using machine learning(ML)and experimental analysis.A Random Forest model was trained using genes known to influence ad-abaxial polarity as ground *** expression data from various tissues and conditions as well as promoter regulation data derived from transcription factor chromatin immunoprecipitation sequencing(ChIP-seq)was used as input,enabling the prediction of novel ad-abaxial polarity-related genes and additional transcription *** to this,available and newly-obtained transcriptome data enabled us to identify genes differentially expressed across leaf ad-abaxial *** on these analyses,we obtained a set of 111 novel genes which are involved in leaf ad-abaxial *** explore implications for vegetable crop breeding,we examined the conservation of expression patterns between Arabidopsis and Brassica rapa using single-cell *** results demonstrated the utility of our computational approach for predicting candidate genes in crop *** findings expand the understanding of the genetic networks governing leaf ad-abaxial differentiation in agriculturally important vegetables,enhancing comprehension of natural variation impacting leaf morphology and development,with demonstrable breeding applications.

关键词： Machine learning Leaf polarity Arabidopsis thaliana Brassica rapa Transcription factor

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TAX1BP1 and FIP200 orchestrate non-canonical autophagy of p62 aggregates for mouse neural stem cell maintenance

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Zoological Research 2024年第4期45卷 937-950页

作者： Yi-Fu Zhu Rong-Hua Yu Shuai Zhou Pei-Pei Tang Rui zhang Yu-Xin Wu Ran Xu Jia-Ming Wei Ying-Ying Wang Jia-Li zhang Meng-Ke Li Xiao-Jing Shi Yu-Wei zhang Guang-Zhi Liu Rick FThorne Xu Dong zhang Mian Wu Song Chen School of Life Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230001China Translational Research Institute of Henan Provincial People’s Hospital and People'’s Hospital of Zhengzhou University Tianjian Laboratory of Advanced Biomedical SciencesAcademy of Medical SciencesZhengzhou UniversityZhengzhouHenan 450053China Institute of Medicinal Biotechnology Jiangsu College of NursingHuai’anJiangsu 223300China Laboratory Animal Center Academy of Medical ScienceZhengzhou UniversityZhengzhouHenan 450052China Henan Key Laboratory of Stem cell Differentiation and Modification Henan Provincial People’s HospitalHenan UniversityZhengzhouHenan 450053China School of Biomedical Sciences and Pharmacy The University of NewcastleNSW 2308Australia

Autophagy plays a pivotal role in diverse biological processes,including the maintenance and differentiation of neural stem cells(NSCs).Interestingly,while complete deletion of Fip200 severely impairs NSC maintenance and differentiation,inhibiting canonical autophagy via deletion of core genes,such as Atg5,Atg16l1,and Atg7,or blockade of canonical interactions between FIP200 and ATG13(designated as FIP200-4A mutant or FIP200 KI)does not produce comparable detrimental *** highlights the likely critical involvement of the non-canonical functions of FIP200,the mechanisms of which have remained ***,utilizing genetic mouse models,we demonstrated that FIP200 mediates non-canonical autophagic degradation of p62/sequestome1,primarily via TAX1BP1 in *** deletion of Tax1bp1 in fip200hGFAP conditional knock-in(cKI)mice led to NSC deficiency,resembling the fip200hGFAP conditional knockout(cKO)mouse ***,reintroducing wild-type TAX1BP1 not only restored the maintenance of NSCs derived from tax1bp1-knockout fip200hGFAP cKI mice but also led to a marked reduction in p62 aggregate ***,a TAX1BP1 mutant incapable of binding to FIP200 or NBR1/p62 failed to achieve this ***,conditional deletion of Tax1bp1 in fip200hGFAP cKO mice exacerbated NSC deficiency and p62 aggregate accumulation compared to fip200hGFAP cKO ***,these findings illustrate the essential role of the FIP200-TAX1BP1 axis in mediating the non-canonical autophagic degradation of p62 aggregates towards NSC maintenance and function,presenting novel therapeutic targets for neurodegenerative diseases.

关键词： Non-canonical autophagy TAX1BP1 FIP200 p62 Aggregates Neural stem cell

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基于自抗扰控制器的永磁同步电机直接转矩控制

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电测与仪表 2024年第1期61卷 195-200页

作者：李少朋谢源张凯贺耀庭上海电机学院电气学院上海201306

针对传统永磁同步电机直接转矩控制(DTC)中转矩和磁链脉动较大以及转速超调的缺点,文中提出了一种基于自抗扰控制器的直接转矩控制策略。对于传统的PI控制策略中的磁链环、转矩环以及转速环不能满足控制系统非线性的需求,所提出的控制... 详细信息

针对传统永磁同步电机直接转矩控制(DTC)中转矩和磁链脉动较大以及转速超调的缺点,文中提出了一种基于自抗扰控制器的直接转矩控制策略。对于传统的PI控制策略中的磁链环、转矩环以及转速环不能满足控制系统非线性的需求,所提出的控制策略中非线性的自抗扰控制器满足了系统的非线性需求,提高了控制系统的动态响应能力。该策略中使用自抗扰控制器取代了传统PI控制结构,设计磁链、转矩和转速自抗扰控制器。通过搭建半实物仿真平台,进行实验验证文中控制策略的有效性。实验结果表明所提出的控制策略与传统的直接转矩控制相比较,文中提到的控制策略可以有效降低转矩和磁链的波动并提高系统的稳定性,降低了转速超调,改善了系统的动态性能。

关键词：永磁同步电机自抗扰控制器非线性半实物仿真平台

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Predicting dynamic compressive strength of frozen-thawed rocks by characteristic impedance and data-driven methods

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2591-2606页

作者： Shengtao Zhou Zong-Xian zhang Xuedong Luo Yifan Huang Zhi Yu Xiaowei Yang Faculty of Engineering China University of GeosciencesWuhan430074China Oulu Mining School University of OuluOulu90570Finland Zijin School of Geology and Mining Fuzhou UniversityFuzhou350116China Department of Earth Science&Engineering Imperial College LondonLondonSW72AZUK

In cold regions,the dynamic compressive strength(DCS)of rock damaged by freeze-thaw weathering significantly influences the stability of rock ***,testing the dynamic strength under freeze-thaw weathering conditions is often both time-consuming and ***,this study considers the effect of characteristic impedance on DCS and aims to quickly determine the DCS of frozen-thawed rocks through the application of machine-learning ***,a database of DCS for frozen-thawed rocks,comprising 216 rock specimens,was *** external load parameters(freeze-thaw cycle number,confining pressure,and impact pressure)and two rock parameters(characteristic impedance and porosity)were selected as input variables,with DCS as the predicted *** research optimized the kernel scale,penalty factor,and insensitive loss coefficient of the support vector regression(SVR)model using five swarm intelligent optimization algorithms,leading to the development of five hybrid *** addition,a statistical DCS prediction equation using multiple linear regression techniques was *** performance of the prediction models was comprehensively evaluated using two error indexes and two trend indexes.A sensitivity analysis based on the cosine amplitude method has also been *** results demonstrate that the proposed hybrid SVR-based models consistently provided accurate DCS *** these models,the SVR model optimized with the chameleon swarm algorithm exhibited the best performance,with metrics indicating its effectiveness,including root mean square error(RMSE)?3.9675,mean absolute error(MAE)?2.9673,coefficient of determination(R2)?0.98631,and variance accounted for(VAF)?*** suggests that the chameleon swarm algorithm yielded the most optimal results for enhancing SVR ***,impact pressure and characteristic impedance emerged as the two most influential parameters in DCS *** research is ant

关键词： Freeze-thaw cycle Characteristic impedance Dynamic compressive strength Machine learning Support vector regression

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创新主体在城市群知识网络中的角色——基于科学与技术关联视角

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科学学研究 2024年第6期42卷 1288-1299页

作者：滕子优朱雪忠胡成张萱同济大学上海国际知识产权学院上海200092 香港城市大学数据科学学院中国香港999077 江苏大学知识产权学院江苏镇江212013 上海兰迪律师事务所上海200092

基于科学的创新逐渐成为新的创新范式,促进从科学成果在技术创新中的应用有助于在新兴产业获得竞争优势。构建城市群科学到技术的知识流动网络,分析网络中各创新主体的角色,可以助力城市群优化创新主体定位与布局,推进区域科技中心建设... 详细信息

基于科学的创新逐渐成为新的创新范式,促进从科学成果在技术创新中的应用有助于在新兴产业获得竞争优势。构建城市群科学到技术的知识流动网络,分析网络中各创新主体的角色,可以助力城市群优化创新主体定位与布局,推进区域科技中心建设,从而加速科学与技术融合,实现区域高质量发展。分别收集京津冀、长三角和珠三角城市群2001-2020年机构参与的专利引用论文关系,构建创新主体间知识网络。结合社会网络与相关性分析,从整体网络和自我网络两个层面对比城市群知识网络中不同类型创新主体特征。结果发现:(1)本地大学同时承担重要的科学知识输出、输入和中介功能,本地科研机构作用类似,但规模较小。本地大中企业和小微企业多侧重知识吸收,少量具备输出和中介能力;整体上,本地小微企业的知识输出、输入和中介能力最弱;(2)京津冀和长三角知识网络中,本地大学知识输出、输入和中介能力相关性高,本地大中企业和小微企业则缺少显著相关性。珠三角知识网络中,本地大学多侧重于知识吸收或输出之一,本地大中企业知识输出、输入和中介功能相关性高;(3)京津冀和长三角网络中,本地大学与外部主体交流最密切,珠三角网络中本地大中企业与外部主体直接交流程度最高。研究结论为相关区域完善多主体共同参与的科技创新体系提供借鉴。

关键词：科学-技术关联创新主体城市群知识网络专利引用论文

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Heterostructure:application of absorption-catalytic center in lithium-sulfur batteries

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Rare Metals 2024年第4期43卷 1461-1487页

作者： Fei Wang Chun-Man Yang Yong-Qi Wang Dan You Wen-Hao Yang Rong-Wei Huang Ji-Yue Hou Qian Wang Ying-Jie zhang Ying Wang Yue-Jing Zeng Yi-Yong zhang Xue Li National Local Joint Engineering Research Center for Lithium-Ion Batteries and Materials Preparation Technology Key Laboratory of Advanced Batteries Materials of Yunnan ProvinceFaculty of Metallurgical and Energy EngineeringKunming University of Science and TechnologyKunming650093China College of Electrical Information Engineering Panzhihua UniversityPanzhihua617000China State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Centre of Chemistry for Energy MaterialsState-Province Joint Engineering Laboratory of Power Source Technology for New Energy VehicleEngineering Research Center of Electrochemical TechnologyMinistry of EducationCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China

Due to the high theoretical specific capacity(1675 mAh·g^(-1)),low cost,and high safety of the sulfur cathodes,they are expected to be one of the most promising rivals for a new generation of energy storage ***,the shuttle effect,low conductivity of sulfur and its discharge products,volume expansion,and other factors hinder the commercialization of lithium-sulfur batteries(LSBs).The development of sulfur-fixing materials and the design of multifunctional materials to enhance the electrochemical performance of LSBs have been the main research priorities in recent *** of the advantages of high conductivity,built-in electric field,and good synergism,more and more researchers have employed heterostructure into sulfur-fixing materials to enhance the catalytic and absorption ability for *** this review,the principle of heterostructure and the mechanism of enhancing the performance of lithium-sulfur batteries are *** applications of heterostructure in cathode and interlayer of LSBs in the latest years are ***,the cutting-edge troubles and possibilities of heterostructures in LSBs are briefly presented.

关键词： Lithium-sulfur batteries(LSBs) Heterostructure Built-in electric field Catalytic Absorption

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基于优化功率跟随控制的E-REV能量管理策略研究

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车用发动机 2024年第2期 60-67页

作者：刘凯李捷辉章舒韬江苏大学汽车与交通工程学院江苏镇江212013 南京清研海易新能源动力有限责任公司江苏南京211806

基于功率跟随控制的增程式电动汽车能量管理策略具有减缓电池寿命衰减与提高车辆NVH性能等优势,但存在阈值参数依赖性强、增程器启停频繁等问题,为此提出了一种基于优化功率跟随控制的E-REV能量管理策略。依据车速、SOC状态与驾驶员的... 详细信息

基于功率跟随控制的增程式电动汽车能量管理策略具有减缓电池寿命衰减与提高车辆NVH性能等优势,但存在阈值参数依赖性强、增程器启停频繁等问题,为此提出了一种基于优化功率跟随控制的E-REV能量管理策略。依据车速、SOC状态与驾驶员的加速踏板力度等信息特征,制定基于功率跟随控制的能量管理策略。在此基础上,针对固定规则参数的局限性,以车辆行驶总成本与SOC变化梯度为目标函数,结合灰狼优化算法对增程器启停功率阈值参数进行优化,减少发动机频繁启停现象。运用Matlab/Simulink搭建控制策略模型,并联合基于Simcenter/AMESIM搭建的整车物理模型进行仿真试验,结果表明:CHTC-LT循环工况下,优化功率跟随控制策略与功率跟随控制策略相比,SOC最大波动值降低了28%,增程器启停次数减少了28.5%,整车燃油经济性提升了6.89%。

关键词：增程式汽车能量管理功率跟随控制灰狼优化算法燃油经济性

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Preliminary research and scheme design of deep underground in situ geo-information detection experiment for Geology in Time

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International Journal of Mining Science and Technology 2024年第1期34卷 1-13页

作者： Heping Xie Ru zhang Zetian zhang Yinshuang Ai Jianhui Deng Yun Chen Yong Zhou Mingchuan Li Liqiang Liu Mingzhong Gao Zeqian Yang Weiqiang Ling Heng Gao Qijun Hao Kun Xiao Chendi Lou State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering Sichuan UniversityChengdu 610065China College of Water Resource&Hydropower Sichuan UniversityChengdu 610065China Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyShenzhen UniversityShenzhen 518060China Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China Yalong River Hydropower Development Company Limited Chengdu 610051China

The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year *** is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and *** academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the *** on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given *** research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering.

关键词： Deep underground Geology in Time China Jinping Underground Laboratory In situ detection

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Wavefield Separation of Distributed Acoustic Sensing Vertical Seismic Profile Data Based on Multichannel Vector Median Filtering

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Journal of Earth Science 2024年第2期35卷 712-716页

作者： Zijuan Ma Jun Lu Feng zhang Pinbo Ding Zhidong Cai Key Laboratory of Intraplate Volcanoes and Earthquakes Ministry of EducationChina University of GeosciencesBeijing 100083China College of Geophysics China University of PetroleumBeijing 102249China New Resources Geophysical Exploration Division BGP Inc.CNPCZhuozhouHebei 072751China

INTRODUCTION Distributed acoustic sensing(DAS)is a novel and popular technology for vertical seismic profile(VSP)data acquisition because of its many advantages,including full vertical coverage,high sampling density,low cost,and resistance to stressors(high temperature and pressure).The current industrial application of DAS in borehole exploration acquires single-mode *** records strain rates,which are then converted to particle velocities by the modem before being written to the disk.

关键词： Seismic Vertical borehole

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Plasmon-enhanced photocatalytic oxidative coupling of amines in the air using a delicate Ag nanowire@NH_(2)-UiO-66 core-shell nanostructures

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Chinese Chemical Letters 2024年第4期35卷 506-510页

作者： Yuan zhang Shenghao Gong A.R.Mahammed Shaheer Rong Cao Tianfu Liu Fujian Science Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350007China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

MOF-based core-shell structures with high surface area, abundant active sites, and broad absorption bands are viable alternatives to traditional single-component photocatalysts. In this report, we describe the design and construction of delicate Ag nanowires@NH_(2)-UiO-66 with a core-shell structure for use as photocatalysts in imine synthesis under light. The optimized composites exhibited 80% imine production, which was higher than both MOF and Ag NWs. The significant improvement in photocatalytic activity under light may be attributed to the plasmonic effect of silver nanowires and their core-shell structure, which promotes the separation of electron-hole pairs. Moreover, the photocatalytic activity of the core-shell nanostructure may provide valuable insight into the design and construction of MOF-based composite photocatalysts for oxidative coupling of amines.

关键词： Metal-organic frameworks Plasmonic silver nanowires Photocatalyst Core-shell nanostructure Oxidative coupling of amines

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