检索结果-南通市图书馆

High-precision X-ray polarimeter based on channel-cut crystals

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第3期35卷 30-39页

作者： Shang-Yu Si zhong-liang li Wen-Hong Jia lian Xue Hong-Xin Luo Jian-Cai Xu Bai-Fei Shen lin-Gang Zhang liang-liang Ji Yu-Xin Leng Ren-zhong Tai Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Shanghai Institute of Optics and Fine Mechanics Chinese Academy of SciencesShanghai 201800China

We report on using synthetic silicon for a high-precision X-ray polarimeter comprising a polarizer and an analyzer,each based on a monolithic channel-cut crystal used at multiple Brewster reflections with a Bragg angle very close to 45°.Experiments were performed at the BL09B bending magnet beamline of the Shanghai Synchrotron Radiation Facility using a Si(800)crystal at an X-ray energy of 12.914 keV.A polarization purity of 8.4×10^(-9)was *** result is encouraging,as the measured polarization purity is the best-reported value for the bending magnet ***,this is the firstly systematic study on the hard X-ray polarimeter in China,which is crucial for exploring new physics,such as verifying vacuum birefringence.

关键词： X-ray polarimeter Vacuum birefringence Synchrotron radiation Channel-cut crystal

Operando measurement of lattice deformation profiles of synchrotron radiation monochromator

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第7期35卷 8-19页

作者： Yue Zhang zhong-liang li Shang-Yu Si lian Xue Hong-Xin Luo Xiao-Wei Zhang Jun Hu Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai201204China ShanghaiTech University Shanghai201210China University of the Chinese Academy of Sciences Beijing100049China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of ScienceBeijing100049China

This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale thermal lattice deformation on a double-crystal monochromator at different incident *** nanoscale thermal lattice deformation of the monochromator first crystal was obtained by analyzing the intensity of the distorted DuMond *** diagrams of the 333 diffraction index,sensitive to lattice deformation,were obtained directly using a 2D detector and an analyzer crystal orthogonal to the *** increasing incident power and power density,the maximum height of the lattice deformation increased from 3.2 to 18.5 nm,and the deformation coefficient of the maximum height increased from 1.1 to 3.2 nm/*** maximum relative standard deviation was 4.2%,and the maximum standard deviation was 0.1 *** on the measured thermal deformations,the flux saturation phenomenon and critical point for the linear operation of the monochromator were predicted with increasing incident *** study provides a simple solution to the problem of the lower precision of synchrotron radiation monochromator characterizations compared to simulations.

关键词： Synchrotron radiation Monochromator Lattice deformation X-ray dynamic diffraction

Cu/chiral phosphoric acid-catalyzed radical-initiated asymmetric aminosilylation of alkene with hydrosilane

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2019年第11期62卷 1529-1536页

作者： Yang Zeng Xiao-Dong liu Xian-Qi Guo Qiang-Shuai Gu zhong-liang li Xiao-Yong Chang Xin-Yuan liu Shenzhen Grubbs Institute Southern University of Science and TechnologyShenzhen 518055China Academy for Advanced Interdisciplinary Studies Southern University of Science and TechnologyShenzhen 518055China Department of Chemistry Southern University of Science and TechnologyShenzhen 518055Chin

The catalytic radical-initiated asymmetric 1,2-aminosilylation of alkene with a hydrosilane under Cu(I)/CPA cooperative catalysis has been *** method features the use of hydrosilane as the reductive radical precursor,enabling efficient access to skeletally diverse silicon-containing azaheterocycles including pyrrolidine,indoline and isoindoline bearing anα-tertiary stereocenter with high *** key to the success includes the use of Cu(I)/CPA cooperative catalyst system and theβ-silicon effect of the silyl group to stabilize the in situ generated carbocation intermediate.

关键词： asymmetric radical chemistry aminosilylation alkenes Cu/chiral phosphoric acid silyl radical

Development of aperiodic multilayer mirrors operated at W-Lβline for plasma diagnostics application

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2023年第11期34卷 77-84页

作者： Ze‑Hua Yang Jing‑Tao Zhu zhong‑liang li Hong‑Xin Luo Shang‑Yu Si Yun‑Ping Zhu li Zhao Kuan Ren Feng Wang Rong‑Qing Yi Shanghai Synchrotron Radiation Facility(SSRF) Shanghai Institute of Applied PhysicsChinese Academy of Sciences(CAS)Shanghai 201203China Key Laboratory of Advanced Micro‑Structured Materials Ministry of EducationSchool of Physics and EngineeringTongji UniversityShanghai 200092China State Key Laboratory of Surface Physics Department of PhysicsFudan UniversityShanghai 200438China Thin‑Film Optics Laboratory Hongce Optoelectronics LtdSuzhou 215431China Research Center of Laser Fusion China Academy of Engineering PhysicsMianyang 621900China

Multilayer interference mirrors play a pivotal role in spectroscopic diagnostic systems,which probe electron temperature and density during inertial confinement fusion *** this study,aperiodic Mo/B_(4)C multilayer mirrors of varied thick-nesses were investigated for X-ray plasma diagnostics at the 9.67-keV W-Lβ*** thickness distribution of the aperiodic multilayers was designed using the first Bragg diffraction condition and then optimized through a simplex algorithm to realize a narrow bandwidth and consistent spectral *** enhance spectral accuracy,further refinements were undertaken by matching the grazing incidence X-ray reflectivity data with actual structural parameters.X-ray reflectivity measurements from the SSRF synchrotron radiation facility on the optimized sample showed a reflectivity of 29.7±2.6%,flat-band range of 1.3 keV,and bandwidth of 1.7 keV,making it suitable for high-temperature plasma *** study explored the potential of predicting the 9.67 keV reflectivity spectrum using the fitting data from the grazing incidence X-ray reflectivity curves at 8.05 ***,the short-term thermal stability of an aperiodic multilayer was assessed using temperature-dependent in situ X-ray *** in the reflectivity spectrum during annealing were attributed to interdiffusion and interfacial *** research team recommends the aperiodic Mo/B_(4)C multilayer mirror for operations below 300℃.

关键词： X-ray multilayer mirror Aperiodic multilayer Flat response Sputtering deposition Synchrotron radiation

CD4^＋CD25^＋ regulatory T lymphocytes in tuberculous pleural effusion

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2008年第7期 581-586页

作者： QIN Xue-jun SHI Huan-zhong liang Qiu-li HUANG Lu-ying YANG Hai-bo Institute of Respiratory Diseases First Affiliated HospitalGuangxi Medical University Nanning Guangxi 530021 China

Background Active suppression by CD4^＋CD25^＋ regulatory T lymphocytes plays an important role in the down-regulation of T cell responses to foreign and self-antigens. This study was conducted to analyze whether the CD4^＋CD25^＋ regulatory T cells exist and function normally in tuberculous pleural effusion. Methods The percentages of CD4^＋CD25^＋ T cells in pleural effusion and peripheral blood from patients with tuberculous pleurisy and peripheral blood from healthy control subjects were determined by flow cytometry. The expression of forkhead transcription factor Foxp3 was also examined. CD4^＋CD25^＋ and CD4^＋CD25^-T cells from pleural effusion and blood were isolated, and were cultured to observe the effects of CD4^＋CD25^＋ T cells on proliferation response of CD4^＋CD25^- T cells in vitro. Results There were increased numbers of CD4^＋CD25^＋ T cells in tuberculous pleural effusion compared with peripheral blood from both patients with tuberculous pleurisy and normal subjects, and these cells demonstrated a constitutive high-level expression of Foxp3. Moreover, CD4^＋CD25^＋ T cells mediated potent inhibition of proliferation response of CD4^＋CD25^- T cells. Conclusion The increased CD4^＋CD25^＋ T cells in tuberculous pleural effusion express a high level of Foxp3 transcription factor, while potently suppressing the proliferation of CD4^＋CD25^- T cells.

关键词： CD4^+CD25^+ T cells pleural effusion regulatory T cells tuberculosis

Copper-Catalyzed Enantioconvergent Radical C(sp^(3))−N Cross- Coupling to Access Chiral α-Amino-β-lactams

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Precision Chemistry 2023年第10期1卷 576-582页

作者： Jing-Jing Zheng Wei-Long liu Qiang-Shuai Gu zhong-liang li Ji-Jun Chen Xin-Yuan liu Shenzhen Key Laboratory of Cross-Coupling Reactions Southern University of Science and TechnologyShenzhen 518055China Shenzhen Grubbs Institute and Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China Academy for Advanced Interdisciplinary Studies and Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China

A copper-catalyzed enantioconvergent radical C-(sp^(3))-N cross-coupling of racemic tertiaryα-bromo-β-lactams with aromatic amines is developed under mild thermal reaction *** use of a sterically demanded oxazoline-derived sulfonamide N,N,N-ligand is crucial for the reaction initiation and effective enantio-discrimination of the azetidinone-derived cyclic alkyl *** strategy provides an attractive approach to access chiralα-amino-β-lactams,an important structural motif in many biologically active *** mechanistic studies support the formation of azetidinone-derived alkyl radicals from the L*Cu(I)-amido complex andα-bromo-β-lactams.

关键词： copper asymmetric radical reactions cross-coupling aromatic amines chiralα-amino-β-lactams

Longer duration of initial invasive mechanical ventilation is still a crucial risk factor for moderate‑to‑severe bronchopulmonary dysplasia in very preterm infants:a multicentrer prospective study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2023年第6期19卷 577-585页

作者： Cong Dou Yong-Hui Yu Qing-Cui Zhuo Jian-Hong Qi Lei Huang Yan-Jie Ding De-Juan Yang li li Dan li Xiao-Kang Wang Yan Wang Xin Qiao Xiang Zhang Bing-Jin Zhang Hai-Yan Jiang zhong-liang li Simmy Reddy Department of Neonatology Maternal and Child Health Care Hospital of Shandong ProvinceShandong UniversityJinan 250014China Department of Neonatology Shandong Provincial Hospital affiliated to Shandong First Medical UniversityHuaiYin DistrictNo.324Jingwu RoadJinan 250021China Department of Neonatology Shandong Provincial HospitalShandong UniversityHuaiYin DistrictNo.324Jingwu RoadJinan 250021China Department of Neonatology Qilu Hospital of Shandong UniversityJinan 250012China Department of Neonatology Shandong Provincial Maternal and Child Health Care HospitalJinan 250014China Department of Neonatology Yantai Yuhuangding HospitalYantai 264000China Department of Neonatology The First Affiliated Hospital of Shandong First Medical UniversityJinan 250014China Department of Neonatology Linyi People’s HospitalLinyi 276000China Department of Neonatology Liaocheng People’s HospitalLiaocheng 252000China Department of Neonatology The Affiliated Taian City Central Hospital of Qingdao UniversityTaian 271000China Department of Neonatology Jinan Maternity and Child Healthcare HospitalJinan 250001China Department of Neonatology Hebei Petro China Central HospitalLangfang 065000China Department of Neonatology Shengli Olifield Central HospitalDongying 257000China Department of Neonatology The Third Hospital of Baogang GroupBaotou 014000China Department of Neonatology W.F.Maternal and Child Health HospitalWeifang 261011China Cheeloo College of Medicine Shandong UniversityJinan 250000China

Objectives We aimed to evaluate the risk factors for moderate-to-severe bronchopulmonary dysplasia(BPD)and focus on discussing its relationship with the duration of initial invasive mechanical ventilation(IMV)in very preterm neonates less than 32 weeks of gestational age(GA).Methods We performed a prospective cohort study involving infants born at 23–31 weeks of GA who were admitted to 47 different neonatal intensive care unit(NICU)hospitals in China from January 2018 to December *** data were obtained from the Sina-northern Neonatal Network(SNN)*** We identified 6538 very preterm infants,of whom 49.5%(3236/6538)received initial IMV support,and 12.6%(823/6538)were diagnosed with moderate-to-severe BPD *** median duration of initial IMV in the moderateto-severe BPD group was 26(17–41)days,while in the no or mild BPD group,it was 6(3–10)*** incidence rate of moderate-to-severe BPD and the median duration of initial IMV were quite different across different *** logistic regression analysis showed that the onset of moderate-to-severe BPD was significantly associated with the duration of initial IMV[adjusted odds ratio(AOR):1.97;95%confidence interval(CI):1.10–2.67],late-onset neonatal sepsis(LONS),and patent ductus arteriosus(PDA).Conclusion In this multicenter cohort study,the duration of initial IMV was still relatively long in very premature infants,and the longer duration of initial IMV accounts for the increased risk of moderate-to-severe BPD.

关键词： Bronchopulmonary dysplasia Invasive mechanical ventilation Multicenter cohort-Preterm infants Prospective

Copper-Catalyzed Asymmetric Three-Component Radical 1,2-Carboamination of Acrylamides with Arylamines: Access to Chiral α-Tertiary N-Arylamines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第11期6卷 2652-2661页

作者： Jia-Heng Fang Ji-Jun Chen Xuan-Yi Du Zhe Dong Run-Yan Tian Chang-Jiang Yang Fu-li Wang Cheng Luan zhong-liang li Xin-Yuan liu School of Chemistry and Chemical Engineering Harbin Institute of TechnologyHarbin 150001 Shenzhen Grubbs Institute Department of ChemistryGuangming Advanced Research InstituteShenzhen Key Laboratory of CrossCoupling ReactionsSouthern University of Science and TechnologyShenzhen 518055 Department of Chemistry and Dongguan Key Laboratory for Data Science and Intelligent Medicine Great Bay UniversityDongguan 523000 Dongguan Key Laboratory of Interdisciplinary Science for Advanced Materials and Large-Scale Scientific Facilities School of Physical SciencesGreat Bay UniversityDongguan 523000

The asymmetric radical carboamination of 1,1-disubstituted alkenes from readily available alkyl halides and arylamines provides expedient access to valueadded chiralα-tertiary N-arylamines but has been less recognized.A challenge arises mainly from the difficult reaction initiation inherent in alkyl halides and the construction of fully substituted chiral C–N bonds from sterically congested tertiary alkyl ***,we report a copper-catalyzed asymmetric three-component radical carboamination of acrylamides utilizing an anionic chiral N,N,N-ligand under mild *** ligand was essential for the reaction initiation by enhancing the reducing capability of copper and enabling the enantiocontrol over tertiary alkyl *** substrate scope was broad,covering an array of acrylamides,aryl-and heteroaryl-amines,as well as alkyl halides and sulfonyl chlorides,enabling good functional group *** combined with the follow-up transformation,this strategy provides a versatile platform for accessing structurally diverse chiralα-tertiary N-arylamine building blocks of interest in organic synthesis.

关键词： asymmetric catalysis copper alkenes radical reactions chiral amines

Expression of soluble triggering receptor expression on myeloid cells-1 in pleural effusion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2008年第17期121卷 1656-1661页

作者： HUANG Lu-ying SHI Huan-zhong liang Qiu-li WU Yan-bin QIN Xue-jun CHEN Yi-qiang Institute of Respiratory Diseases First Affiliated Hospital Guangxi Medical University Nanning Guangxi 530021 China

Background Triggering receptors expressed on myeloid cells （TREM） proteins are a family of cell surface receptors expressed broadly by cells of the myeloid lineage. The aim of this study was to investigate the clinical significance of soluble TREM-1 （sTREM-1） in pleural effusions, and to determine the effects of pneumonia on pleural sTREM-1 concentrations. Methods Pleural fluid was collected from 109 patients who presented to the respiratory institute （35 with malignant pleural effusion, 31 with tuberculous pleural effusion, 21 with bacterial pleural effusion, and 22 with transudate）. The concentrations of sTREM-1, tumor necrosis factor-a （TNF-a） and interleukin-113 （IL-113） were determined in effusion and serum samples by enzyme linked immunosorbent assay （EliSA）. Results The concentrations of sTREM-1 in bacterial pleural effusion were significantly higher than those in malignant, tuberculous, and transudative groups （all P 〈0.001）. An sTREM-1 cutoff value of 768.1 ng/L had a sensitivity of 86% and a specificity of 93%. Pleural sTREM-1 levels were positively correlated with levels of TNF-a and IL-113. Patients with complicating bacterial pneumonia did not have elevated concentration of sTREM-1 in pleural effusion when compared with patients without pneumonia. Conclusions Determination of pleural sTREM-1 may improve the ability of clinicians to differentiate pleural effusion patients of bacterial origin from those with other etiologies. The occurrence of bacterial pneumonia did not affect pleural sTREM-1 concentrations.

关键词： pleural effusion empyema infection