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Influence of hydraulic retention time on behavior of antibiotics and antibiotic resistance genes in aerobic granular reactor treating biogas slurry

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Frontiers of Environmental Science & Engineering 2019年第3期13卷 59-67页

作者： Jie Liao Chaoxiang Liu Lin Liu Jie Li Hongyong fan Jiaqi Ye zhichao Zeng Key Laboratory of Environmental Biotechnology Fujian Province University Xiamen University of Technology Xiamen 361024 China Key Laboratory of Urban Pollutant Conversion Institute of Urban Environment Chinese Academy of Sciences Xiamen 361021 China Fujian Institute of Innovation Chinese Academy of Sciences Fuzhou 350002 China

The behavior of antibiotics and the corresponding resistance genes in aerobic granular reactors for treating biogas slurry under different hydraulic retention times (10.7 h, Rl;8 h, R2) was investigated in this study. The results indicated that the hydraulic retention time could affect the effluent concentrations and removal efficiencies of sulfonamides. The average removal rates of tetracyclines, fluoroquinolones, and sulfonamides were 63%, 46%, and 90% in Rl, and 62%, 46%, and 86% in R2, respectively. Although the removal efficiencies of tetracyclines and fluoroquinolones were similar in both reactors, the respective accumulated concentrations of tetracyclines and fluoroquinolones in R1 were 7.00 and 11.15μg/g SS, which were lower than those in R2 (8.92 and 13.37μg/g SS, respectively). The difference in the relative abundance of target antibiotic resistance genes between both reactors was not significant, yet the average relative abundances of all target resistance genes in R1 were higher than those in R2 after 45 days of operation. The results of this study suggested that a longer hydraulic retention time could enhance the antibiotic removal ability of aerobic granular sludge, yet it may also increase the risk of surplus sludge utilization from a resistance genes point of view.

关键词： Aerobic granules Swine wastewater Tetracyclines Fluoroquinolones Sulfonamides

Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries

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Neural Regeneration Research 2012年第2期7卷 114-118页

作者： Hongling fan Yuanyin Zheng Lijuan Xu zhichao Zhong Shining Cai Shuling Zhang Quanzhong Chang Department of Physiology Zhuhai Campus of Zunyi Medical College Zhuhai 519041 Guangdong Province China

An ischemic-hypoxic animal model was established using right common carotid artery occlusions and inhalation of low concentrations of oxygen in mice. At 10 days after the ischemic-hypoxic injuries, saline-treated mice exhibited significantly prolonged escape latencies in water-maze tests and significantly shorter memory latencies and more mistakes in step-down tests. In contrast, mice treated with 5 mg/kg minocycline exhibited significant reversals of each of these effects compared with the saline-treated control mice. Moreover, we found that minocycline can relieve brain water content and morphological changes in mice following ischemic-hypoxic cerebral injuries. Accordingly, our findings indicate that minocycline provides some protections against the deleterious effects of these injuries in mice.

关键词： minocycline ischemic-hypoxic cerebral injury learning and memory cognition

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五轴联动机床虚拟加工系统构建及仿真验证

煤矿机械 2024年第2期45卷 168-171页

作者：张健霍凤伟林志超任宝钢营口理工学院机械与动力工程学院辽宁营口115014 通用技术集团沈阳机床有限责任公司沈阳110142

五轴联动机床具有3个直线轴和2个回转轴,能在一次装夹中完成复杂曲面及异形几何特征类零件加工。实际加工过程中,刀具与工件相对运动复杂,常遇到刀具干涉。基于此,以五轴联动机床为研究对象,进行机床结构的运动链分析和零部件建模、装配... 详细信息

五轴联动机床具有3个直线轴和2个回转轴,能在一次装夹中完成复杂曲面及异形几何特征类零件加工。实际加工过程中,刀具与工件相对运动复杂,常遇到刀具干涉。基于此,以五轴联动机床为研究对象,进行机床结构的运动链分析和零部件建模、装配,进而阐述了虚拟加工系统构建方法。最后以风扇叶轮加工为例,在已构建的系统上进行仿真验证。结果表明,该系统可以模拟双转台型五轴联动机床实际切削运动过程,可以发现加工过程中可能存在的干涉、碰撞等,对实际生产起到一定的指导作用。该研究不仅可以为类似五轴数控机床虚拟加工系统构建提供借鉴,而且对提高加工仿真技术及五轴机床应用水平也具有重要的价值。

关键词：五轴联动机床虚拟加工仿真

二郎山—折多山大渡河深切峡谷区地质灾害发育特征及对输变电工程的影响

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四川电力技术 2024年第3期47卷 39-45,51页

作者：范荣全曾文慧夏敏张文涛任志超罗毅许文杰陈中国国网四川省电力公司经济技术研究院四川成都610041 地质灾害防治与地质环境保护国家重点实验室(成都理工大学) 四川成都610059

以二郎山—折多山大渡河深切峡谷区输电走廊沿线为研究对象,基于遥感解译及地质灾害调查对区内地质灾害发育特征以及对输变电工程的影响进行了研究。结果表明:研究区内地质灾害主要形成控制因素有地形地貌、坡向、地质构造、工程地质岩... 详细信息

以二郎山—折多山大渡河深切峡谷区输电走廊沿线为研究对象,基于遥感解译及地质灾害调查对区内地质灾害发育特征以及对输变电工程的影响进行了研究。结果表明:研究区内地质灾害主要形成控制因素有地形地貌、坡向、地质构造、工程地质岩组、年降雨量等;地质灾害主要分布于2200 m以下高程,坡度介于15°~50°,崩塌主要发育于坚硬或较坚硬岩,滑坡发育于软硬互层岩组;崩塌、滑坡主要分布于降雨量为834~965 mm的区域,泥石流主要分布于降雨量为892~1085 mm的区域;二郎山—折多山大渡河深切峡谷区输电走廊沿线现状地质灾害发育对输变电工程的杆塔及其基础的稳定性造成威胁。研究成果可为输电走廊沿线地质灾害评价与防治提供理论依据,为输变电工程规划选线、设计及施工提供技术指导。

关键词：地质灾害大渡河深切峡谷输变电工程

Structural and functional imaging of brains

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Science China Chemistry 2023年第2期66卷 324-366页

作者： zhichao Liu Ying Zhu Liming Zhang Weiping Jiang Yawei Liu Qiaowei Tang Xiaoqing Cai Jiang Li Lihua Wang Changlu Tao Xianzhen Yin Xiaowei Li Shangguo Hou Dawei Jiang Kai Liu Xin Zhou Hongjie Zhang Maili Liu Chunhai fan Yang Tian Shanghai Key Laboratory of Green Chemistry and Chemical Processes School of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai200241China Interdisciplinary Research Center Shanghai Synchrotron Radiation FacilityZhangjiang LaboratoryShanghai Advanced Research InstituteChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai201210China State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Chinese Academy of SciencesWuhan National Laboratory for OptoelectronicsWuhan430071China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China Department of Chemistry Tsinghua UniversityBeijing100084China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesInstitute of Translational MedicineShanghai Jiao Tong UniversityShanghai200240China Interdisciplinary Center for Brain Information Brain Cognition and Brain Disease InstituteShenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsFaculty of Life and Health SciencesShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China Lingang Laboratory Shanghai201602China School of Biomedical Engineering Shanghai Jiao Tong UniversityShanghai200240China Institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen518055China Department of Nuclear Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Analyzing the complex structures and functions of brain is the key issue to understanding the physiological and pathological *** neuronal morphology and local distribution of neurons/blood vessels in the brain have been known,the subcellular structures of cells remain challenging,especially in the live *** addition,the complicated brain functions involve numerous functional molecules,but the concentrations,distributions and interactions of these molecules in the brain are still poorly *** this review,frontier techniques available for multiscale structure imaging from organelles to the whole brain are first overviewed,including magnetic resonance imaging(MRI),computed tomography(CT),positron emission tomography(PET),serial-section electron microscopy(ss EM),light microscopy(LM)and synchrotron-based X-ray microscopy(XRM).Specially,XRM for three-dimensional(3D)imaging of large-scale brain tissue with high resolution and fast imaging speed is ***,the development of elegant methods for acquisition of brain functions from electrical/chemical signals in the brain is *** particular,the new electrophysiology technologies for neural recordings at the single-neuron level and in the brain are also *** also focus on the construction of electrochemical probes based on dual-recognition strategy and surface/interface chemistry for determination of chemical species in the brain with high selectivity and long-term stability,as well as electrochemophysiological microarray for simultaneously recording of electrochemical and electrophysiological signals in the ***,the recent development of brain MRI probes with high contrast-to-noise ratio(CNR)and sensitivity based on hyperpolarized techniques and multi-nuclear chemistry is ***,multiple optical probes and instruments,especially the optophysiological Raman probes and fiber Raman photometry,for imaging and biosensing in live brain are emphas

关键词： brain structure brain function brain chemistry chemical signal biosensing and bioimaging

Optimization and experiment of key components in pneumatic peanut pod conveyor

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International Journal of Agricultural and Biological Engineering 2020年第3期13卷 100-107页

作者： Xuemei Gao Huanxiong Xie Fengwei Gu Hai Wei Minji Liu Jianchun Yan zhichao Hu Nanjing Research Institute for Agricultural Mechanization Ministry of Agriculture and Rural AffairsNanjing 210014China

Research interest in pneumatic conveying technologies in processes such as peanut harvesting and shelling has grown rapidly in recent ***,the use of pneumatic conveyors in this application suffers from high pod damage rates and duct *** address these issues,we analyzed the critical speed of pneumatic transport for conveying the peanut pods and measured the angle of friction and coefficient of restitution of peanut pods on a variety of material *** on the results of these tests,optimizations and improvements were made to the separator bowl,air supply duct,and conveying duct.A pneumatic conveying experiment was then performed using peanut *** the factorial experiment,it was found that increases in fan speed increase the pod damage rate and transport efficiency,while increases in the thickness of the cushioning/anti-obstruction layer decrease the rate of pod damage and transport *** damage rates were significantly affected by fan speed,the thickness of the cushioning/obstruction prevention layer,and interaction between these factors,while transport efficiency was only significantly affected by fan *** is proved by the machine verification test,the optimal parameters for the pneumatic transport of Baisha peanut pods with a moisture content of 7.24%was a fan speed of 2700 r/min and a cushioning/anti-obstruction layer thickness of 6 mm.A pod damage rate of 5.19%and transport efficiency of 92.03%were achieved using these parameters,which are sufficient for meeting the requirements of industrial applications.

关键词： pneumatic transport material properties of peanut pods damage rate transport efficiency

Model Free Adaptive Control Algorithm based on ReOSELM for Autonomous Driving Vehicles

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Model Free Adaptive Control Algorithm based on ReOSELM for A...

Tabbed Routing 阻抗能力探究

第40届中国控制会议

作者： Xiaofei Zhang Hongbin Ma zhichao Wang Mingyu fan Bolin Zhao School of Automation Beijing Institute of Technology State Key Laboratory of Intelligent Control and Decision of Complex Systems Beijing Institute of Technology The College of Computer Science and Artificial Intelligence Wenzhou University

Different road conditions and dynamic environment bring significant challenges to the control system of autonomous driving vehicle（ADV）. As is known, historical data collected from ADV contains valuable information about control systems,therefore, it is a promising thing to study adaptive control algorithms that have certain learning ability. In order to improve the control performance of ADV and the efficiency in data usage, in this paper, a model free adaptive control algorithm based on regularized online sequential extreme learning machine（ReOSELM） is introduced, it is difficult to analyze the algorithm based on neural network, and the system stability by improved update algorithm of ReOSELM is proved. Simulation results indicate that the proposed algorithm is effective in improving control precision when ADV is turning, and experimental results on an autonomous driving vehicle show that this algorithm is effective in real environment.

关键词： data-driven control autonomous driving vehicle model free adaptive control regularized online sequential extreme learning machine

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印制电路信息 2024年第S1期32卷 34-42页

作者：张志超陈富嘉彭镜辉蓝小强黎钦源广州广合科技股份有限公司广东广州510730

高速服务器主板主芯片到存储器的高速信号传输通过Double Data Rate(简称DDR)技术实现,传输高速信号的连接线简称为DDR阻抗线。因主芯片相对存储器位置能布设管脚的空间要小,从主芯片到存储器的DDR高速阻抗线呈扇出形状,主芯片位置的阻... 详细信息

高速服务器主板主芯片到存储器的高速信号传输通过Double Data Rate(简称DDR)技术实现,传输高速信号的连接线简称为DDR阻抗线。因主芯片相对存储器位置能布设管脚的空间要小,从主芯片到存储器的DDR高速阻抗线呈扇出形状,主芯片位置的阻抗线线宽相对存储器位置要小,存在阻抗不连续问题。对靠近主芯片位置的DDR阻抗线增加规则的凸耳状走线可提升整段DDR阻抗不匹配问题。增加规则的凸耳走线的阻抗线又称Tabbed Routiing阻抗(简称TAB阻抗)。探究布设不同形状和不同尺寸的TAB设计来提升阻抗不连续问题,根据材料等级选择一种最佳的布线设计模式,对TAB阻抗设计及生产制作控制都有较大指导意义。

关键词：高速服务器主板高速传输信号

Behavior of multiple modes before and during minor disruption with the external resonant magnetic perturbations on J-TEXT tokamak

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Plasma Science and Technology 2022年第6期24卷 88-95页

作者： Mingxiang HUANG Zhengkang REN Feiyue MAO Zhoujun YANG Yuan GAO zhichao ZHANG Shunfan HE Guoliang LI Jinrong fan Wei TIAN Nengchao WANG Zhipeng CHEN Yonghua DING Yuan PAN Zhongyong CHEN College of Computer Science South-Central Minzu UniversityWuhan 430074People's Republic of China International Joint Research Laboratory of Magnetic Confinement Fusion and Plasma Physics State Key Laboratory of Advanced Electromagnetic Engineering and TechnologySchool of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074People's Republic of China

The behavior of multiple modes before and during minor disruption with the external resonant magnetic perturbations(RMPs)has been studied on a J-TEXT *** main component of RMPs is m/n=2/1,where m and n are the numbers of the poloidal and toroidal modes,*** the mode-locking caused by RMPs,it is found that before a minor or a major disruption(if there is no minor disruption),strong oscillations in both electron temperature and density occur if the edge safety factor q_(a)>*** analysis shows that the oscillations are caused by the m/n=3/1 *** addition,using the ECE,Mirnov coils and 2D electron cyclotron emission imaging diagnostic systems,it is found that a thermal collapse occurs on the inner side of the 2/1magnetic island during the minor disruption,and before the collapse,a 3/2 island increases,after the collapse,the 3/2 island may ***,the study also shows that these 3/1,2/1 and 3/2modes play roles in the thermal collapse of disruptions.

关键词： oscillation multiple modes disruption