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Improving hydrogen storage thermodynamics and kinetics of Ce-Mg-Ni-based alloy by mechanical milling with TiF_(3)

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Journal of Magnesium and Alloys 2024年第4期12卷 1593-1607页

作者： Hongwei Shang wei Zhang Xin wei Yaqin Li Zeming yuan Jun Li Yanghuan Zhang School of Mechanical and Electrical Engineering Chuzhou UniversityChuzhou 239000China Department of Functional Material Research Central Iron and Steel Research InstituteNo.76 Xueyuannan RoadHaidian DistrictBeijing 100081China Key Laboratory of Integrated Exploitation of Bayan-Obo Multi-Metal Resources Inner Mongolia University of Science and TechnologyBaotou 014010China China Rare Earth New Material(weishan)Co. Ltd.Jining 277600China

Mg-based hydrides are too stable and the kinetics of hydrogen absorption and desorption is not *** efficient way to improve these shortcomings is to employ reactive ball milling to synthesize the nanocomposite materials of Mg and *** this experiment,TiF_(3)was selected as an additive,and the mechanical milling method was employed to prepare the experimental *** alloys used in this experiment were the as-cast Ce_(5)Mg_(85)Ni_(10),as-milled Ce_(5)Mg_(85)Ni_(10)and Ce_(5)Mg_(85)Ni_(10)+3 wt.%*** phase transformation,structural evolution,isothermal and non-isothermal hydrogenation and dehydrogenation performances of the alloys were inspected by XRD,SEM,TEM,Sievert apparatus,DSC and *** revealed that nanocrystalline appeared in the as-milled *** with the as-cast alloy,ball milling made the particle dimension and grain size decrease dramatically and the defect density increase *** addition of TiF_(3)made the surface of ball milling alloy particles markedly coarser and more *** milling and adding TiF_(3)distinctly improved the activation and kinetics of the ***,ball milling along with TiF_(3)can decrease the onset dehydrogenation temperature of Mg-based hydrides and slightly ameliorate their thermodynamics.

关键词： Mg-based hydrides TiF_(3) Ball milling Thermodynamics Kinetics

Competitive assembling strategy to construct carbon nitride homojunctions for boosting photocatalytic performance

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Journal of Materials Science & Technology 2024年第5期172卷 23-32页

作者： Hua-wei Zhang yuan-yuan Li Bo Li Jing-Hui Shi Tao Huang Gui-Fang Huang Anlian Pan Wangyu Hu wei-Qing Huang School of Physics&Electronic Engineering Zhengzhou University of Light IndustryZhengzhou 450002China Key Laboratory for Micro/Nano Optoelectronic Devices of Ministry of Education&Hunan Provincial Key Laboratory of Low-Dimensional Structural Physics and Devices School of Physics and ElectronicsHunan UniversityChangsha 410082China College of Materials Science and Engineering Hunan UniversityChangsha 410082China

Both morphology and composition have a great influence on the properties and functions of materials,however,how to rational modulate both of them to achieve their synergistic effects has been a longstanding ***,we demonstrate a competitive assembling strategy for the construction of metal-free graphite carbon nitride(CN)homojunctions in which morphology and composition can be easily controlled simultaneously by only changing the ratio of assembly raw *** homojunctions are comprised of porous nanotubular S-doped CN(SCN)grafted with CN nanovesicles,which are derived from thermal polycondensation of melamine-thiocyanuric acid(M-T)/melamine-cyanuric acid(M-C)supramolecular hybrid *** unique architecture and component engineering endows the novel SCN-CN homojunction with abundant active sites,enhanced visible trapping ability,and intimate interface *** a result,the synthesized SCN-CN homojunctions demonstrate high photocatalytic activity for hydrogen evolution and pollutant *** developed strategy opens up intriguing opportu-nities for the rational construction of intricate metal-free heterostructures with controllable architecture and interfacial contact for applications in energy-related fields.

关键词： Competitive assembling strategy Supramolecular hybrid blocks Homojunctions Graphite carbon nitride Photocatalytic

Epidermal visualized health monitoring system based on stretchable and washable TPU hybrid conductive microtextiles

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Rare Metals 2024年第7期43卷 3185-3193页

作者： Jing-Bo yuan zhi-Hong Feng Dong-Chan Li Yang Luo Yun-Lei Zhou School of Chemical Engineering Hebei University of Technology Engineering Research Center of Chemical Technology for Efficient Utilization of Seawater ResourcesMinistry of EducationTianjin 300401China National Key Laboratory of Application Specific Integrated Circuit Shijiazhuang050000China Department of Materials ETH Zürich8093 ZurichSwitzerland Hangzhou Institute of Technology Xidian UniversityHangzhou 311231China

Electronic textiles,an emerging class of electronic technology,offer exciting opportunities for seamless integration with the human *** applications have been developed based on electronic ***,researches on integrating multiple electronic textilebased devices are still *** this study,we present a system integrated with an electrocardiogram monitoring sensor and an electroluminescence device based on stretchable and washable conductive micro *** signal is acquired by an electrocardiograph amplifier and displayed by a dual-color electroluminescence device based on the processed *** integrated electronic device has excellent moisture permeability and comfort for long-term *** system reported in this study opens a new avenue for the application of electronic textiles in health monitoring,robotic prosthetics,and competitive sports.

关键词： Conductive microtextile Textile composite Electronic textile Electroluminescent displays

Inducible RNA targeting and N^(6)-methyladenosine editing by a split-Cas13 architecture

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Journal of Molecular Cell Biology 2024年第1期16卷 66-69页

作者： Yang Li Qiang Sun zhi Yang Gang yuan International Institutes of Medicine the Fourth Affiliated Hospital of Zhejiang University School of MedicineYiwu 322000China Department of Thoracic Surgery and Institute of Thoracic Oncology West China HospitalSichuan UniversityChengdu 610041China Future Health Laboratory Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100China

Dear editor,Cas13,a class Ⅱ type Ⅵ CRISPR‒Cas endonuclease with two higher eukaryotes and prokaryotes nucleotide-binding(HEPN)domains,exclusively binds to and cleaves single-stranded RNA by a complementary guide RNA(gRNA)(Makarova et al.,2020).RfxCas13d(also known as CasRx)is an ortholog of CRISPR‒Cas13 with a relatively small size and robust RNA knockdown capability in mammalian cells(Konermann et al.,2018).Owing to its simplicity and high efficiency,CasRx has been applied for RNA targeting in various types of cells and ***,most of these studies failed to control the nuclease activity of CasRx *** re-engineered split-Cas9 system enables inducible genome editing and epigenetic modulation through chemical-induced reassembly of the Cas9 protein(Zetsche et al.,2015).However,tools that allow for efficient and controllable RNA knockdown by a split-Cas13 system remain to be established.

关键词： split system simplicity

Pichia pastoris composition expressed aerolysin mutant of Aeromonas veronii as an oral vaccine evaluated in zebrafish(Danio rerio)

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Marine Life Science & Technology 2024年第3期6卷 475-487页

作者： yuan-yuan Yao Qing-Shuang Zhang Shu-Bin Liu Hong-wei Yang Xing-Yu Chen Ya-Lin Yang Chen-Chen Gao Chao Ran Tsegay Teame Zhen Zhang zhi-Gang Zhou Key Laboratory for Feed Biotechnology of the Ministry of Agriculture Institute of Feed Research of Chinese Academy of Agricultural SciencesBeijing 100081China Sino-Norway Fish Gastrointestinal Microbiota Joint Lab Institute of Feed Research of Chinese Academy of Agricultural SciencesBeijing 100081China Institute of Marine Sciences Shantou UniversityShantou 515063China Tigray Agricultural Research Institute(TARI)Mekelle Center Tigray 7101Ethiopia

Vaccines are one of the most practical means to stop the spreading of Aeromonas veronii in *** this study,virulence factor aerolysin mutant NTaer which has lost its hemolytic activity was used as a target *** pastoris constitutive secretory expression NTaer(GS115-NTaer)was used as a potential safe oral vaccine to evaluate its effectiveness on zebrafish *** result shows that vaccination of GS115-NTaer for four weeks did not affect the growth performance of the host,while eliciting an effective immune protective *** with the control group,the GS115-NTaer could significantly up-regulate the relative expression level of the intestinal tight junction protein 1α(TJP1α)gene,and significantly increased the contents of lysozyme(LYZ),complement C3 and C4 in the gut,indicating that the innate immune response of the fish was *** relative gene expression levels of macrophage-expressed gene 1(MPEG1)and T cell receptor(TCR-α)in the gut,and MPEG1,CD4,CD8,TCR-α,GATA3,and T-bet in the spleen were all increased significantly,indicating that the cellular immune response of the fish was ***,the contents of serum IgM and intestinal mucosa IgZ antibodies were significantly increased,which showed that humoral immunity was also ***,inoculation with GS115-NTaer significantly changed the structure of gut *** particular,the relative ratio of(Firmicutes+Fusobacteriota+Bacteroidota)/Proteobacteria was significantly higher than that of the control and GS115 ***,the vaccinated fish were challenged with ***,and the relative percent survival of GS115 and the GS115-NTear groups was 14.28%and 33.43%.This improvement of immunity was not only due to the specific immune response but also attributed to the improvement of innate immunity and the gut microbiota which was demonstrated by the germ-free zebrafish ***,this study provides information on the effectiveness of GS115-NTear

关键词： Aeromonas veronii Aerolysin mutant NTaer Oral vaccine Immune response Gut microbiota

Dual-curvilinear beam enabled tunable manipulation of high-and low-refractive-index particles

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Photonics Research 2024年第7期12卷 1427-1436页

作者： ZHENG yuan CHENCHEN ZHANG yuan GAO WENXIANG YAN XIAN LONG zhi-CHENG REN XI-LIN WANG JIANPING DING HUI-TIAN WANG National Laboratory of Solid State Microstructures and School of Physics Nanjing UniversityNanjing 210093China Collaborative Innovation Center of Advanced Microstructures Nanjing 210093China Collaborative Innovation Center of Solid-State Lighting and Energy-Saving Electronics Nanjing 210093China

We present an innovative approach for the simultaneous agile manipulation of high-refractive-index(HRI) and low-refractive-index(LRI) particles. Our method involves introducing a dual-curvilinear optical vortex beam(DC-OVB) generated by superimposing a pair of curved beams: HRI and LRI particles are controlled by the bright curve and the dark channel between the two curves, respectively. The proposed DC-OVB provides customizable motion paths and velocities for both LRI and HRI particles. Each curve of the DC-OVB can support a distinct orbital flow density(OFD), enabling the application of torques to HRI and LRI particles, guiding them to orbit along specified trajectories and prompting them to execute various curvilinear motions simultaneously,including curvilinear movement, revolution, and rotation.

关键词： tunable refractive beam

Development and performance evaluation of high temperature resistant strong adsorption rigid blocking agent

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Petroleum Science 2024年第4期21卷 2650-2662页

作者： Zhe Xu Jin-Sheng Sun Jing-Ping Liu Kai-He Lv Xiao-Dong Dong Zong-Lun Wang Tai-Feng Zhang yuan-wei Sun zhi-Wen Dai School of Petroleum Engineering China University of Petroleum (East China) CNPC Engineering Technology R&D Company Limited

As drilling wells continue to move into deep ultra-deep layers, the requirements for temperature resistance of drilling fluid treatments are getting higher and higher. Among them, blocking agent, as one of the key treatment agents, has also become a hot spot of research. In this study, a high temperature resistant strong adsorption rigid blocking agent(QW-1) was prepared using KH570 modified silica,acrylamide(AM) and allyltrimethylammonium chloride(TMAAC). QW-1 has good thermal stability,average particle size of 1.46 μm, water contact angle of 10.5., has a strong hydrophilicity, can be well dispersed in water. The experimental results showed that when 2 wt% QW-1 was added to recipe A(4 wt% bentonite slurry+0.5 wt% DSP-1(filtration loss depressant)), the API filtration loss decreased from 7.8to 6.4 m L. After aging at 240.C, the API loss of filtration was reduced from 21 to 14 m L, which has certain performance of high temperature loss of filtration. At the same time, it is effective in sealing 80-100mesh and 100-120 mesh sand beds as well as 3 and 5 μm ceramic sand discs. Under the same conditions,the blocking performance was superior to silica(5 μm) and calcium carbonate(2.6 μm). In addition, the mechanism of action of QW-1 was further investigated. The results show that QW-1 with amide and quaternary ammonium groups on the molecular chain can be adsorbed onto the surface of clay particles through hydrogen bonding and electrostatic interaction to form a dense blocking layer, thus preventing further intrusion of drilling fluid into the formation.

关键词： High adsorption Rigid microsphere High temperature resistance Blocking performance

Elevated peripheral levels of receptor-interacting protein kinase 1(RIPK1)and IL-8 as biomarkers of human amyotrophic lateral sclerosis

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Signal Transduction and Targeted Therapy 2024年第1期9卷 271-278页

作者： Jun wei Min Li zhi Ye Xinqian Hu Xiaoyan He Jia Wang Gaofeng Chen Chengyu Zou Daichao Xu Hongbing Zhang Junying yuan Yunhong Zha Institute of Neural Regeneration and Repair and Department of Neurology The First College of Clinical Medical ScienceYichang Central HospitalCollege of Basic Medical ScienceChina Three Gorges UniversityHubei Province Clinical Medical Research Center for Rare Diseases of Nervous SystemYichang 443000China Interdisciplinary Research Center on Biology and Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai Key Laboratory of Aging StudiesShanghai 201210China State Key Laboratory of Common Mechanism Research for Major Diseases Haihe Laboratory of Cell EcosystemDepartment of PhysiologyInstitute of Basic Medical Sciences and School of Basic MedicineChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Amyotrophic lateral sclerosis(ALS)is a devastating fatal neurodegenerative disease with no ***-interacting protein kinase 1(RIPK1)has been proposed to mediate pathogenesis of *** has been identified as an old drug that can also inhibit RIPK1 *** conducted a drug-repurposing biomarker study of primidone as a RIPK1 inhibitor using SOD1G93A mice and ALS ***1G93A mice treated with primidone showed significant delay of symptomatic onset and improved motor ***-hundred-sixty-two ALS participants dosed daily with primidone(62.5 mg)completed 24-week follow-up.A significant reduction was showed in serum levels of RIPK1 and IL-8,which were significantly higher in ALS patients than that of healthy controls(P<0.0001).Serum RIPK1 levels were correlated positively with the severity of bulbar symptoms(P<0.05).Our study suggests that serum levels of RIPK1 and IL-8 in peripheral can be used as clinical biomarkers for the activation of RIPK1 in central nervous system in human ALS *** primidone may provide a promising therapeutic strategy for *** effect of primidone for the treatment of other inflammatory diseases may also be considered,since the activation of RIPK1 has been implicated in mediating a variety of inflammatory diseases including COVID-19-associated cytokine release syndrome(CRS).(ChiCTR2200060149).

关键词： RIPK1 diseases Serum

Mapping multiple phases in curcumin binary solid dispersions by fluorescence contrasting

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Chinese Chemical Letters 2024年第9期35卷 266-272页

作者： Ying Xu Chengying Shen Hailong yuan wei Wu Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China Center for Medical Research and Innovation Shanghai Pudong HospitalFudan University Pudong Medical CenterShanghai 201399China Department of Pharmacy Air Force Medical CenterPLABeijing 100142China Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006China

The microphases and miscibility in binary curcumin(Cur)solid dispersions(SDs)with amorphous polyvinylpyrrolidone K30(PVP K30)and semi-crystalline poloxamer(P407)and poly(ethylene glycol)6000(PEG6000)as carriers were investigated by fluorescence contrasting utilizing confocal laser scanning microscopy.A super sensitive fluorophore P4 with typical aggregation-caused quenching properties was employed to stain the continuous polymer phases and contrasted with the autofluorescence of the model drug *** addition,differential scanning calorimetry(DSC)and powder X-ray diffraction(PXRD)were utilized to assist in explanation of the fluorescence *** all three SD systems,there is always a homogenous polymer phase stained by P4 and it is difficult to adulterate Cur crystals by ***-enriched rather than polymer-enriched domains could be *** the Cur-PVP K30 system,Cur exists in an amorphous form at a Cur loading level of 50%and below,while Cur crystallines phase out and continuously grow with the increase of Cur loading from 60%to 90%.The phase behaviors in the Cur-P407 and Cur-PEG 6000 systems are similar but with minor *** both systems,Cur phases out as clusters of drug-enriched domains at a loading level of 20%and below,which however cannot be correlated with crystallization,as evidenced by both DSC and *** is a transition from an amorphous to a crystalline state from 20%to 30%Cur loading,above which Cur crystallines can be *** is interesting that a co-mix phase of both Cur-and PEG 6000-enriched domains can be identified at Cur loading levels of 10%and *** together,it is concluded that contrasting Cur autofluorescence with the signals of P4 proves to be a functional strategy to reveal multiple phases in the binary SD systems investigated.

关键词： Solid dispersion Curcumin PEG PVP Poloxamer Fluorescence Environment-responsive Confocal laser scanning microscopy