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Simulation of open channel flows by an explicit incompressible mesh-free method

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Journal of Hydrodynamics 2023年第2期35卷 287-298页

作者： zhi-jian huang Ti-bing Xu David Z.Zhu Song-da Zhang School of Civil and Environmental Engineering and Geography Science Ningbo UniversityNingbo315211China Department of Civil and Environmental Engineering University of AlbertaAlbertaCanada Ningbo River Management Center Ningbo315303China

In this study,to simulate open channel flows,an explicit incompressible mesh-free method is employed in which the pressure field is obtained by explicitly solving the pressure Poisson *** capture the velocity information in open channel flows,the source term in the pressure Poisson equation is modified while the spatial discretization of gradient and Laplacian models is based on the moving particle semi-implicit(MPS)*** inflow boundary condition is treated by injecting fluid particles into the domain according to the inlet discharge,and the outflow condition is handled by prescribing the pressure distribution and removing the fluid particles beyond the *** explicit incompressible mesh-free method is then used to simulate open channel flows,including weir flow,hydraulic jump,and flow over an *** the simulations,velocity distribution and flow pattern are *** simulated results are compared to available experimental measurements and other numerical *** is a good agreement between the simulated results and the experimental *** shows that the explicit incompressible mesh-free method can reproduce the flow characteristics in the open channel flows.

关键词： Mesh-free method explicit scheme weir flow hydraulic jump velocity distribution

Quantum Information Splitting Based on Current Cavity QED Techniques

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Communications in Theoretical Physics 2008年第5期49卷 1165-1168页

作者： WU Huai-zhi YANG Zhen-Biao SU Wan-Jun ZHONG zhi-Rong huang jian-Min Department of Electronic Science and Applied Physics Fuzhou University Fuzhou 350002 China

We propose two schemes for quantum information splitting via W-class state. The first scheme is based on the interaction of single atom with single-mode field, while the second scheme is based on the simultaneous interaction of two atoms with single-mode cavity. For the first scheme, the difIiculty of two atoms required to be simultaneously sent through one cavity is avoid. For the second scheme, it is immune to thermal field. Both schemes are experimentally feasible based on current cavity QED techniques.

关键词： resonant interaction thermal field information splitting

Cosmological Constraints on Neutrino Masses in Light of JWST Red and Massive Candidate Galaxies

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Research in Astronomy and Astrophysics 2024年第4期24卷 7-12页

作者： jian-Qi Liu zhi-Qi huang Yan Su School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-Macao Greater Bay Area Zhuhai 519082China

The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~*** the scenario of a low or moderate star formation efficiency,because massive neutrinos tend to suppress the growth of structure of the universe,the JWST observation tightens the upper bound of the neutrino *** A cold dark matter cosmology and a star formation efficiency∈[0.05,0.3](flat prior),we perform joint analyses of Planck+JWST and Planck+BAO+JWST,and obtain improved constraints∑m_(ν)<0.196 eV and ∑m_(ν)+<0.111 eV at 95% confidence level,*** on the above assumptions,the inverted mass ordering,which implies ∑m_(ν)≥0.1 eV,is excluded by Planck+BAO+JWST at 92.7% confidence level.

关键词： (cosmology:)cosmological parameters galaxies:abundances galaxies:formation neutrinos

Liquid-phase epitaxial layer by layer brushing fabrication of metalorganic frameworks films

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Nano Research 2024年第6期17卷 5698-5704页

作者： Li-Mei Chang Rui Zhai zhi-Zhou Ma jian-Dong huang zhi-Gang Gu jian Zhang College of Chemistry Fuzhou UniversityFuzhou 350108China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of Chinese Academy of Sciences Beijing 100049China

Development of metal-organic framework(MOF)films is of great importance to expand their ***,we report a facile and universal method of liquid-phase epitaxial(LPE)layer by layer(LBL)brushing approach for fabricating MOF films on various substrates in a high-throughput *** MOF films preparation method offers a great prospective to cost-effectively construct films with short preparation time and little reagent ***,this LBL brushing approach has been implemented successfully to assemble various MOF films,including HKUST-1,zeolitic imidazolate framework-8(ZIF-8),Cu(bdc),and Cu_(2)(L)_(2)P(L=bdc,ndc,and cam;P=dabco and bipy).Afterwards,the classic MOF HKUST-1 and ZIF-8 films were grown on sensor chip electrode and porous fiber support for good volatile organic compounds(VOCs)selective sensing and water purification *** study demonstrates that this LBL brushing preparation method can be employed to synthesize various MOF films with a variety of characteristics to realize their sensing and separation applications.

关键词： metal-organic framework porous materials layer by layer fabrication film

Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice

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Neural Regeneration Research 2020年第12期15卷 2318-2326页

作者： Chao Zhou Hong Chen jian-Feng Zheng Zong-Duo Guo zhi-jian huang Yue Wu jian-Jun Zhong Xiao-Chuan Sun Chong-Jie Cheng Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Emerging evidence indicates that pentraxin 3 is an acute-phase protein that is linked with the immune response to *** is also a newly discovered marker of anti-inflammatory A2 reactive astrocytes,and potentially has multiple protective effects in stroke;however,its role in the adult brain after traumatic brain injury is *** the present study,a moderate model of traumatic brain injury in mice was established using controlled cortical *** models were intraventricularly injected with recombinant pentraxin 3(the recombinant pentraxin 3 group)or an equal volume of vehicle(the control group).The sham-operated mice underwent craniotomy,but did not undergo the controlled cortical *** potential neuroprotective and neuroregenerative roles of pentraxin 3 were investigated on days 14 and 21 after traumatic brain *** blot assay showed that the expression of endogenous pentraxin 3 was increased after traumatic brain injury in ***,the neurological severity test and wire grip test revealed that recombinant pentraxin 3 treatment reduced the neurological severity score and increased the wire grip score,suggesting an improved recovery of sensory-motor *** Morris water maze results demonstrated that recombinant pentraxin 3 treatment reduced the latency to the platform,increased the time spent in the correct quadrant,and increased the number of times traveled across the platform,thus suggesting an improved recovery of cognitive *** addition,to investigate the effects of pentraxin 3 on astrocytes,specific markers of A2 astrocytes were detected in primary astrocyte cultures in vitro using western blot *** results demonstrated that pentraxin 3 administration activates A2 *** explore the protective mechanisms of pentraxin 3,immunofluorescence staining was *** injection of recombinant pentraxin 3 increased neuronal maintenance in the peri-injured cortex and ipsilateral hippocampus,inc

关键词： brain injury brain trauma cells neurogenesis plasticity protein recovery regeneration

Different outcomes of serpiginous choroiditis with or without ocular and systemic treatment

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International Journal of Ophthalmology(English edition) 2012年第4期5卷 535-538页

作者： Zhong-Shan Chen Qin Ding Yan-Ping Song Li Zhu zhi-jian huang and Ming Yan Department of Ophthalmology Wuhan General Hospital of Guangzhou Military Command Wuhan 430070 Hubei Province China

Study of primordial deuterium abundance in Big Bang nucleosynthesis

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Nuclear Science and Techniques 2024年第3期35卷 208-215页

作者： zhi-Lin Shen jian-Jun He Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Institute of Radiation Technology Beijing Academy of Science and TechnologyBeijing 100875China

Big Bang nucleosynthesis(BBN)theory predicts the primordial abundances of the light elements^(2) H(referred to as deuterium,or D for short),^(3)He,^(4)He,and^(7) Li produced in the early *** these,deuterium,the first nuclide produced by BBN,is a key primordial material for subsequent *** date,the uncertainty in predicted deuterium abundance(D/H)remains larger than the observational *** this study,the Monte Carlo simulation code PRIMAT was used to investigate the sensitivity of 11 important BBN reactions to deuterium *** found that the reaction rate uncertainties of the four reactions d(d,n)^(3)He,d(d,p)t,d(p,γ)^(3)He,and p(n,γ)d had the largest influence on the calculated D/H ***,the calculated D/H uncertainty cannot reach observational precision even with the recent LUNA precise d(p,γ)^(3) He *** the nuclear physics aspect,there is still room to largely reduce the reaction-rate uncertainties;hence,further measurements of the important reactions involved in BBN are still necessary.A photodisintegration experiment will be conducted at the Shanghai Laser Electron Gamma Source Facility to precisely study the deuterium production reaction of p(n,γ)d.

关键词： Big Bang nucleosynthesis Abundance of deuterium Reaction cross section Reaction rate Monte Carlo method

Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury

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Neural Regeneration Research 2022年第3期17卷 577-586页

作者： Wei Tang Zong-Duo Guo Wei-Na Chai Dong-Lin Du Xiao-Min Yang Lang Cao Hong Chen Chao Zhou Chong-Jie Cheng Xiao-Chuan Sun zhi-jian huang jian-Jun Zhong Department of Neurosurgery First Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Ophthalmology First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Micro RNA-491-5 p(miR-491-5 p) plays an important role in regulating cell proliferation and migration;however,the effect of miR-491-5 p on neovascularization after traumatic brain injury remains poorly *** this study,a controlled cortical injury model in C57 BL/6 mice and an oxygen-glucose deprivation model in microvascular endothelial cells derived from mouse brain were established to simulate traumatic brain injury in vivo and in vitro,*** the in vivo model,quantitative real-time-polymerase chain reaction results showed that the expression of miR-491-5 p increased or decreased following the intracerebroventricular injection of an miR-491-5 p agomir or antagomir,respectively,and the expression of miR-491-5 p decreased slightly after traumatic brain *** detect the neuroprotective effects of miR-491-p,neurological severity scores,Morris water maze test,laser speckle techniques,and immunofluorescence staining were assessed,and the results revealed that miR-491-5 p downregulation alleviated neurological dysfunction,promoted the recovery of regional cerebral blood flow,increased the number of lectin-stained microvessels,and increased the survival of neurons after traumatic brain *** the in vitro experiments,the potential mechanism of miR-491-5 p on neovascularization was explored through quantitative real-time-polymerase chain reaction,which showed that miR-491-5 p expression increased or decreased in brain microvascular endothelial cells after transfection with an miR-491-5 p mimic or inhibitor,***-luciferase reporter and western blot assays verified that metallothionein-2 was a target gene for miR-491-5 *** counting kit 8(CCK-8) assay,flow cytometry,and 2′,7′-dichlorofluorescein diacetate(DCFH-DA) assay results confirmed that the downregulation of miR-491-5 p increased brain microvascular endothelial cell viability,reduced cell apoptosis,and alleviated oxidative stress under oxygen-glucose deprivation conditions.C

关键词： brain injury cell migration cell proliferation endothelial cell hypoxia-inducible factor-1 alpha metallothionein 2 microRNA neovascularization neurons vascular endothelial growth factor

Identification of differentially expressed mRNAs as novel predictive biomarkers for gastric cancer diagnosis and prognosis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1947-1964页

作者： jian-Wei Zhou Yi-Bing Zhang zhi-Yang huang Yu-Ping Yuan Jie Jin Department of Gastroenterology Wenzhou Central HospitalDingli Clinical College of Wenzhou Medical UniversityThe Second Affiliated Hospital of Shanghai UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND Gastric cancer(GC)has a high mortality rate *** significant progress in GC diagnosis and treatment,the prognosis for affected patients still remains *** To identify important candidate genes related to the development of GC and iden-tify potential pathogenic mechanisms through comprehensive bioinformatics *** The Gene Expression Omnibus database was used to obtain the GSE183136 dataset,which includes a total of 135 GC *** limma package in R software was employed to identify differentially expressed genes(DEGs).Thereafter,enrichment analyses of Gene Ontology(GO)terms and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways were performed for the gene modules using the clusterProfile package in R *** protein-protein interaction(PPI)networks of target genes were constructed using STRING and visualized by Cytoscape *** common hub genes that emerged in the cohort of DEGs that was retrieved from the GEPIA database were then screened using a Venn *** expression levels of these overlapping genes in stomach adenocarcinoma samples and non-tumor samples and their association with prognosis in GC patients were also obtained from the GEPIA database and Kaplan-Meier ***,real-time quantitative polymerase chain reaction(RT-qPCR)and western blotting were performed to determine the mRNA and protein levels of glutamic-pyruvic transaminase(GPT)in GC and normal immortalized cell *** addition,cell viability,cell cycle distribution,migration and invasion were evaluated by cell counting kit-8,flow cytometry and transwell ***,we also conducted a retrospective analysis on 70 GC patients diagnosed and surgically treated in Wenzhou Central Hospital,Dingli Clinical College of Wenzhou Medical University,The Second Affiliated Hospital of Shanghai University between January 2017 to December *** tumor and adjacent normal samples were collected from the patients to determine the

关键词： Gastric cancer Differentially expressed genes Bioinformatics Hub genes Prognosis