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A new hopane triterpenoid from Saxiglossum angustissimum

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Chinese Chemical Letters 2008年第7期19卷 835-836页

作者： Hui Fang Pi zhi hong Zhong Han li Ruan Peng Zhang Yong Hui Zhang Ji Zhou Wu Faculty of Pharmaceutical Sciences Tongji Medical College of Huazhong University of Science and Technology Wuhan 430030 PR China

A new hopane triterpenoid, hopane 22, 29-diol-29-formate （1）, has been isolated from the whole herbs of Saxiglossum angustissimum （Cries.） Ching and its structure has been successfully determined on the basis of s... 详细信息

关键词： Saxiglossum angustissimum Hopane Hopane-22 29-Diol-29-formate

Metal/covalent organic frameworks for aqueous rechargeable zinc-ion batteries

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Science China Chemistry 2024年第1期67卷 247-259页

作者： Hu hong Xun Guo Jiaxiong Zhu Zhuoxi Wu Qing li Chunyi zhi Department of Materials Science and Engineering City University of Hong KongHong Kong 999077China

lithium-ion batteries(liBs)have become one of the most successful energy storage systems due to their high operating voltage,high energy density,and long cycle ***,with the widespread use of liBs in recent decades,lithium resources are at risk of being ***,it is necessary to find a substitute for liBs to meet the needs of future large-scale energy storage *** of their competitiveness,low cost,and high safety,aqueous rechargeable zinc-ion batteries(ARZIBs)are regarded as promising components in the post-lithium-ion-battery *** the tunable composition,ordered porous channels,and controllable structure of metal-organic frameworks(MOFs)and covalent organic frameworks(COFs),these frameworks are viewed as potential materials for developing high-performance *** this review,we focus on the recent developments in the applications of MOF-/COF-based materials in ARZIBs,including in electrode materials,anode modifications,separators,and solid *** then focus on the critical factors and optimization techniques of MOF-/COF-based materials that affect the performance of ***,we conclude with some projections for the expansion of ARZIBs containing MOF-/COF-based materials.

关键词： metal/covalent organic frameworks aqueous zinc-ion batteries electrode materials anode modifications separators electrolytes

Epigenetic regulation in metabolic diseases:mechanisms and advances in clinical study

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Signal Transduction and Targeted Therapy 2023年第4期8卷 1434-1460页

作者： Yan-lin Wu Zheng-Jun lin Chang-Chun li Xiao lin Su-Kang Shan Bei Guo Ming-Hui Zheng Fuxingzi li ling-Qing Yuan zhi-hong li National Clinical Research Center for Metabolic Disease Department of Metabolism and EndocrinologyThe Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Department of Orthopaedics The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Hunan Key Laboratory of Tumor Models and Individualized Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Department of Radiology The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China

Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases,such as diabetes,obesity,non-alcoholic fatty liver disease(NAFLD),osteoporosis,gout,hyperthyroidism,hypothyroidism and *** term‘epigenetics’was firstly proposed in 1942 and with the development of technologies,the exploration of epigenetics has made great *** are four main epigenetic mechanisms,including DNA methylation,histone modification,chromatin remodelling,and noncoding RNA(ncRNA),which exert different effects on metabolic *** and non-genetic factors,including ageing,diet,and exercise,interact with epigenetics and jointly affect the formation of a *** epigenetics could be applied to diagnosing and treating metabolic diseases in the clinic,including epigenetic biomarkers,epigenetic drugs,and epigenetic *** this review,we introduce the brief history of epigenetics as well as the milestone events since the proposal of the term‘epigenetics’.Moreover,we summarise the research methods of epigenetics and introduce four main general mechanisms of epigenetic ***,we summarise epigenetic mechanisms in metabolic diseases and introduce the interaction between epigenetics and genetic or non-genetic ***,we introduce the clinical trials and applications of epigenetics in metabolic diseases.

关键词： diseases clinical mechanisms

Monopole effects, core excitations, and β decay in the A = 130 hole nuclei near ^(132)Sn

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Chinese Physics C 2019年第5期43卷 35-40页

作者： Han-Kui Wang zhi-hong li Cen-Xi Yuan zhi-Qiang Chen Ning Wang Wei Qin Yi-Qi He College of Physics and Telecommunication Engineering Zhoukou Normal University China Institute of Atomic Energy Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen University School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University College of mathematics and statistics Zhoukou Normal University

The proton and neutron cross-shell excitations across the Z = 50 shell are investigated in the southwest quadrant of ^(132) Sn by large-scale shell-model calculations with extended pairing and multipole-multipole force. The model space allows proton(neutron) core excitations, and both the low-and high-energy states for ^(130) In are well described, as found by comparison with the experimental data. The monopole effects between the proton orbit and neutron orbit are studied as the new monopole correction that perfectly reproduces the first 1^+ level in ^(130) In. The energy interval of proton(neutron) core excitations in ^(130) In lies in the range of 4.5-6.5(2.0-4.1) MeV, and the high energy yrast states are predicted as neutron core excitations. The decays are calculated among the A=130 nuclei of ^(130) In, ^(130) Sn and ^(130) Cd.

关键词： monopole effects core-excitations β decay hole nuclei

Determination of Average Wall Thickness of Mesoporous Silica

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Chinese Chemical Letters 2001年第8期12卷 741-744页

作者： zhi hong li Yan Jun GONG Dong WU Yu Han SUN Jun WANG Yi liU Bao Zhong DONG State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesP.O.Box 165Taiyuan 030001 Laboratory of Synchrotron Radiation Institute of High Energy PhysicsChinese Academy of SciencesP.O.Box 918Beijing 100039

Small Angle X-ray Scattering (SAXS) experiment using Synchrotron Radiation as X-ray source was used to determine the average wall thickness of mesoporous silica prepared by condensation of tetraethylorthosilicate (TEOS) using non-ionic alkylpolyethyleneoxide (AEO(9)) surfactant as templates. The results agreed with that of high-resolution TEM (HRTEM) measurement.

关键词： Small Angle X-ray Scattering(SAXS) mesoporous silica average wall thickness

Epidermal visualized health monitoring system based on stretchable and washable TPU hybrid conductive microtextiles

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Rare Metals 2024年第7期43卷 3185-3193页

作者： Jing-Bo Yuan zhi-hong Feng Dong-Chan li Yang Luo Yun-Lei Zhou School of Chemical Engineering Hebei University of Technology Engineering Research Center of Chemical Technology for Efficient Utilization of Seawater ResourcesMinistry of EducationTianjin 300401China National Key Laboratory of Application Specific Integrated Circuit Shijiazhuang050000China Department of Materials ETH Zürich8093 ZurichSwitzerland Hangzhou Institute of Technology Xidian UniversityHangzhou 311231China

Electronic textiles,an emerging class of electronic technology,offer exciting opportunities for seamless integration with the human *** applications have been developed based on electronic ***,researches on integrating multiple electronic textilebased devices are still *** this study,we present a system integrated with an electrocardiogram monitoring sensor and an electroluminescence device based on stretchable and washable conductive micro *** signal is acquired by an electrocardiograph amplifier and displayed by a dual-color electroluminescence device based on the processed *** integrated electronic device has excellent moisture permeability and comfort for long-term *** system reported in this study opens a new avenue for the application of electronic textiles in health monitoring,robotic prosthetics,and competitive sports.

关键词： Conductive microtextile Textile composite Electronic textile Electroluminescent displays

Searching for plant NLR immune receptors conferring resistance to potyviruses

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The Crop Journal 2024年第1期12卷 28-44页

作者： Xin hong Shufen li Xiaofei Cheng Haijian zhi Jinlong Yin Kai Xu Jiangsu Key Laboratory for Microbes and Functional Genomics Jiangsu Engineering and Technology Research Center for MicrobiologyCollege of Life SciencesNanjing Normal UniversityNanjing 210023JiangsuChina College of Plant Protection Northeast Agricultural UniversityHarbin 150030HeilongjiangChina National Center for Soybean Improvement National Key Laboratory for Crop Genetics and Germplasm EnhancementKey Laboratory of Biology and Genetic Improvement of Soybean-Ministry of AgricultureNanjing Agricultural UniversityNanjing 210095JiangsuChina

To fight against invasion by pathogens,plants have evolved an elaborate innate immune system,of which the nucleotide-binding domain leucine-rich repeat-containing receptor(NLR)acts as the sensor and immune ***,comprising one of the largest genera of plant viruses,cause severe crop yield losses *** crop resistance to potyviruses can be used in breeding and plant transgenesis to control disease *** review summarizes achievements in mapping and cloning NLR genes conferring dominant resistance against potyvirus in the families Fabaceae,Solanaceae,Brassicaceae,and *** compares mechanisms of potyviral protein recognition and downstream signaling employed by NLRs and discusses strategies for exploiting NLRs to better control diseases caused by potyviruses.

关键词： NLR Potyvirus resistance Genetic diversity Mapping Engineer

Thoracic spinal cord injury and paraplegia caused by intradural cement leakage after percutaneous kyphoplasty: A case report

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World Journal of Clinical Cases 2024年第10期12卷 1837-1843页

作者： Zi Mao zhi-hong Xiong Jun-Feng li Department of Pain Management The Affiliated Hospital of Yunnan UniversityKunming 650000Yunnan ProvinceChina Department of Medical Administration The Affiliated Hospital of Yunnan UniversityKunming 650000Yunnan ProvinceChina

BACKGROUND Percutaneous kyphoplasty(PKP)is a pivotal intervention for osteoporotic fractures,pathological vertebral compression fractures,and vertebral bone *** its efficacy,the procedure presents challenges,notably complications arising from intradural cement *** and accurate diagnosis,coupled with emergent intervention is imperative to improve patient *** case report illuminates the intricacies and potential complications associated with PKP,emphasizing the critical need for vigilant monitoring,prompt diagnosis,and immediate intervention to mitigate adverse *** SUMMARY A 58-year-old male patient,experiencing a T7 osteoporosis-related pathological compression fracture,underwent PKP at a local *** weeks postprocedure,the patient developed paraplegic and dysuric symptoms,necessitating emergency decompression *** improvement was achieved,marked by the restoration of muscle strength,sensation,and *** PKP Intradural cement leakage following PKP is unusual and potentially *** imaging examinations,urgent evaluation,and the decompression surgery are essential,which help alleviate symptoms associated with spinal damage,markedly improving the overall prognosis.

关键词： Percutaneous kyphoplasty Intradural cement leakage Complication Decompression surgery Case report

Consideration on immunotherapy of liver metastases of malignant tumors

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2374-2381页

作者： Chuang Jiang zhi-hong Zhang Jia-Xin li Division of liver Surgery Department of General Surgery and Laboratory of Liver Surgeryand State Key Laboratory of Biotherapy and Collaborative Innovation Center of BiotherapyWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of General Surgery Dafang County People's HospitalBijie 551600Guizhou ProvinceChina

In this editorial,we comment on the article“Analysis of the impact of immuno-therapy efficacy and safety in patients with gastric cancer and liver metastasis”by liu et al that was published in the recent issue of the World Journal of Gastroin-testinal *** has prompted us to think and summarize some thoughts on immunotherapy for malignant tumor liver *** plays a crucial role in the treatment of malignant tumors;however,the presence of liver metastases in advanced tumors may impact its *** patients with liver metastases can still benefit from immunotherapy,multiple clinical studies have indicated that,compared to other sites of metastasis,liver metastases may diminish the effectiveness of *** efficacy of immune checkpoint inhibitors in patients with liver metastases often fails to reach the ideal level,primarily due to the liver metastases exploiting the host's peripheral immune to-lerance mechanisms to promote systemic CD8(+)T cell exhaustion,resulting in a systemic immune-tolerant *** article aims to summarize the reasons for the decreased efficacy of immunotherapy following liver metastasis in various malignant tumors and propose potential clinical strategies for manage-ment.

关键词： liver metastasis Immunotherapy Immune tolerance Cancer Treatment