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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 307-318页

作者： Lu Xu zhi-hao Xie Jun Li Shi Tao Fang-Li Ren Yin-Yin Wang zhi-Jie Chang Xin-Bao hao Department of Hematology The First Affiliated Hospital of Hainan Medical UniversityHaikou570102China State Key Laboratory of Membrane Biology School of MedicineTsinghua UniversityBeijing 100084China Heya Beijing Med-Biotech Inc. Beijing 100084China Department of Hematology Roswell Park Comprehensive Cancer CenterNY 14263USA

Objective:To investigate the role of RPRD1B in the progression of diffuse large B-cell lymphoma(DLBCL)and its potential as a therapeutic ***:This study analyzed RPRD1B expression in DLBCL and normal tissues using public databases and assessed its prognostic impact through survival *** vitro and in vivo experiments were conducted to explore the mechanisms by which RPRD1B influences tumor growth and ***:RPRD1B expression was significantly elevated in DLBCL compared to normal tissues and was associated with poor *** vitro and in vivo experiments demonstrated that RPRD1B promoted lymphoma cell proliferation and inhibited apoptosis through the NF-κB signaling ***:RPRD1B plays a critical role in the progression of DLBCL by modulating apoptosis and cellular *** RPRD1B may offer a novel therapeutic strategy for DLBCL,suggesting its potential as a prognostic marker and therapeutic target in hematological malignancies.

关键词： RPRD1B RNAPⅡ Diffuse large B-cell lymphoma NF-κB Apoptosis

Influence of oxygen-rich hot air composite gas medium on sintering performance and function mechanism

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Journal of Iron and Steel Research International 2024年第5期31卷 1071-1081页

作者： Min Gan hao-xiang Zheng Xiao-hui Fan zhi-yun Ji Qiang Li Ming wu Yi-fan Wang Xiao-long Wang Yu-feng wu Xu-ling Chen Zeng-qing Sun Xiao-xian Huang School of Minerals Processing and Bioengineering Central South UniversityChangsha410083HunanChina Shanxi Taigang Stainless Steel Co. Ltd.Taiyuan030003ShanxiChina

Hot air sintering technology is used to improve the quality and production efficiency of sintered ***,the current thick layer condition highlights the disadvantage of the low oxygen potential of the hot air sintering ***,it is considered to use oxygen enrichment sintering to improve the environment of hot air *** sintering,hot air sintering,and oxygen-rich hot air sintering were compared through sintering cup experiments,and the influence of hot air and oxygen-rich hot air on sintering indexes was *** air reduced the vertical sintering velocity,while improved the yield and tumbler ***-rich hot air sintering contributed to improving the vertical sintering velocity while ensuring the quality of sintered ore,thus comprehensively improving production *** the action of hot air,the highest temperature of the sintering layer increased and the high-temperature holding time was *** oxygen enrichment,the combustion efficiency of fuels in the upper layer of materials was promoted,which optimized heat distribution in the middle and lower layers of materials and increased the content of calcium ferrite in the sintered ore,thus strengthening the sintering process.

关键词： Iron ore sintering Hot air sintering Oxygen enrichment Function mechanism

Selective oxidation using in-situ generated hydrogen peroxide over titanosilicates

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Chinese Journal of Structural Chemistry 2024年第6期43卷 12-14页

作者： zhipeng Wan hao Xu Peng wu State Key Laboratory of Petroleum Molecular&Process Engineering Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesSchool of Chemistry and Molecular Engineering East China Normal UniversityShanghai200062China Institute of Eco-Chongming Shanghai202162China

Titanosilicates are a class of heteroatom-containing zeolitic materials with tetrahedrally coordinated Ti^(4+)ions incorporated into crystalline zeolite frameworks,with TS-1,Ti-MWW and Ti-MOR as representative and attractive selective oxidation *** liquid-phase oxidations of a variety of substrates such as olefins and ketones with the green oxidant of H_(2)O_(2)over titanosilicates under mild conditions have attracted considerable research interests in the clean production of fine and bulk chemicals,among which propylene epoxidation and cyclohexanone ammoximation have been industrialized[1].

关键词： silicate zeolite propylene

Combinatorial optimization of perovskite-based ferroelectric ceramics for energy storage applications

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Journal of Advanced Ceramics 2024年第7期13卷 877-910页

作者： Suwei Dai Mengyang Li Xiaowen wu Yunyi wu Xiang Li Yanan hao Bingcheng Luo Engineering Research Center of Ministry of Education for Geological Carbon Storage and Low Carbon Utilization of Resources Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid WastesNational Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of Geosciences BeijingBeijing 100083China College of Science China Agricultural UniversityBeijing 100083China Research Center for Comprehensive Energy Technology CTG Science and Technology Research InstituteBeijing 100038China School of Energy and Power Engineering Beihang UniversityBeijing 100191China State Key Laboratory of Information Photonics and Optical Communications&School of Science Beijing University of Posts and TelecommunicationsBeijing 100876China

With the increasing impacts of climate change and resource depletion,dielectric capacitors,with their exceptional stability,fast charging and discharging rates,and ability to operate under more extreme conditions,are emerging as promising high-demand candidates for high-performance energy storage devices,distinguishing them from traditional electrochemical capacitors and ***,due to the shortcomings of various dielectric ceramics(e.g.,paraelectrics(PEs),ferroelectrics(FEs),and antiferroelectrics(AFEs)),their low polarizability,low breakdown strength(BDS),and large hysteresis loss limit their standalone use in the advancement of energy storage ***,synthesizing novel perovskite-based materials that exhibit high energy density,high energy efficiency,and low loss is crucial for achieving superior energy storage *** this review,we outline the recent development of perovskitebased ferroelectric energy storage ceramics from the perspective of combinatorial optimization for tailoring ferroelectric hysteresis loops and comprehensively discuss the properties arising from the different combinations of *** also provide future guidelines in this ***,the combinatorial optimization strategy in this review will open up a practical route toward the application of new high-performance ferroelectric energy storage devices.

关键词： perovskite hysteresis loop relaxor ferroelectric(RFE) paraelectric(PE) antiferroelectric(AFE) energy storage

Synergistic Interdecadal Evolution of Precipitation over Eastern China and the Pacific Decadal Oscillation during 1951-2015

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Advances in Atmospheric Sciences 2024年第1期41卷 53-72页

作者： Minmin wu Rong-Hua ZHANG Junya HU Hai zhi Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of SciencesQingdao 266071China School of Marine Sciences Nanjing University of Information Science and TechnologyNanjing 210044China Laosan Laboratory Qingdao 266237China School of Atmospheric Sciences Nanjing University of Information Science and TechnologyNanjing 210044China University of Chinese Academy of Sciences Beijing 100029China

By using the multi-taper method(MTM)of singular value decomposition(SVD),this study investigates the interdecadal evolution(10-to 30-year cycle)of precipitation over eastern China from 1951 to 2015 and its relationship with the North Pacific sea surface temperature(SST).Two significant interdecadal signals,one with an 11-year cycle and the other with a 23-year cycle,are identified in both the precipitation and SST *** show that the North Pacific SST forcing modulates the precipitation distribution over China through the effects of the Pacific Decadal Oscillation(PDO)-related anomalous Aleutian low on the western Pacific subtropical high(WPSH)and Mongolia high(MH).During the development stage of the PDO cold phase associated with the 11-year cycle,a weakened WPSH and MH increased the precipitation over the Yangtze River Basin,whereas an intensified WPSH and MH caused the enhanced rain band to move northward to North China during the decay *** the development stage of the PDO cold phase associated with the 23-year cycle,a weakened WPSH and MH increased the precipitation over North China,whereas an intensified WPSH and the weakened MH increased the precipitation over South China during the decay *** 11-year and 23-year variabilities contribute differently to the precipitation variations in the different regions of China,as seen in the 1998flooding *** 11-year cycle mainly accounts for precipitation increases over the Yangtze River Basin,while the 23-year cycle is responsible for the precipitation increase over Northeast *** results have important implications for understanding how the PDO modulates the precipitation distribution over China,helping to improve interdecadal climate prediction.

关键词： MTM-SVD PDO SST anomalies interdecadal variability precipitation over China

Recent Advances in Deuteration Reactions

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Chinese Journal of Chemistry 2024年第10期42卷 1145-1156页

作者： hao Li Muhammad Shabbir wu Li Aiwen Lei Institutefor Advanced Studies(IAS) Collegeof Chemistry and Molecular SciencesWuhan UniversityWuhanHubei 430072China

The deuteration of organic compounds has attracted more attentions in recent years for the potential applications in new drug discovery and synthetic *** this purpose,many efficient deuterium labeling methodologies have been developed,including hydrogen isotope exchange(HIE),reductive deuteration,and dehalogenative deuteration that allow for the synthesis of selectively deuterated *** the last few years,great breakthroughs in selective isotope labeling have been achieved and the interest in new methodologies for the deuteration of organic molecules is *** this review,we summarized the recent developments in the selective deuteration of organic molecules since *** types of key processes in deuterium incorporation reactions,including H/D exchange,reductive deuteration and dehalogenative deuteration,are introduced and discussed.

关键词： Deuterated compounds H/D exchange Reductive deuterations Dehalogenative deuterations Deuterium C-Hactivation Synthetic methods

Aging Mongolian pine plantations face high risks of drought-induced growth decline:evidence from both individual tree and forest stand measurements

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Journal of Forestry Research 2024年第2期35卷 109-120页

作者： Mingyong Li Leilei Yang Yu Cao Dedong wu Guangyou hao CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110016People’s Republic of China Key Laboratory of Terrestrial Ecosystem Carbon Neutrality Liaoning ProvinceShenyang 110016People’s Republic of China Daqinggou Ecological Research Station Institute of Applied EcologyChinese Academy of SciencesShenyang 110016People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China Research Institute of Sand Control and Utilization Liaoning ProvinceFuxin 123000People’s Republic of China

Discerning vulnerability differences among different aged trees to drought-driven growth decline or to mortality is critical to implement age-specific countermeasures for forest management in water-limited *** important species for afforestation in dry environments of northern China,Mongolian pine(Pinus sylvestris *** Litv.)has recently exhibited growth decline and dieback on many sites,particularly pronounced in old-growth ***,changes in response to drought stress by this species with age as well as the underlying mechanisms are poorly *** this study,tree-ring data and remotely sensed vegetation data were combined to investigate variations in growth at individual tree and stand scales for young(9-13 years)and aging(35-52 years)plantations of Mongolian pine in a water-limited area of northern China.A recent decline in tree-ring width in the older plantation also had lower values in satellited-derived normalized difference vegetation indices and normalized difference water indices relative to the younger *** addition,all measured growth-related metrics were strongly correlated with the self-calibrating Palmer drought severity index during the growing season in the older *** of growth to drought of the older plantation might be attributed to more severe hydraulic limitations,as reflected by their lower sapwood-and leaf-specific hydraulic *** study presents a comprehensive view on changes of growth with age by integrating multiple methods and provides an explanation from the perspective of plant hydraulics for growth decline with *** results indicate that old-growth Mongolian pine plantations in water-limited environments may face increased growth declines under the context of climate warming and drying.

关键词： Tree age Drought stress Mongolian pine plantation Tree rings Remote sensing Plant hydraulics

Advancements and Prospects in Continuous Wave Time-resolved Electron Paramagnetic Resonance

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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 2024年第5期40卷 798-805页

作者： Zhang, Shixue Zhou, Shengqi wu, hao Guo, Xingwei Tsinghua Univ Ctr Basic Mol Sci CBMS Dept Chem Beijing 100084 Peoples R China

This brief review highlights the techniques and diverse applications of time-resolved electron paramagnetic resonance (TREPR) spectroscopy, underscoring its essential role in elucidating the structures, spin dynamics, and reactivities of open-shell systems. Furthermore, we discuss the limitations of traditional TREPR methodologies, particularly their challenges in directly observing reactive radical intermediates under real-world reaction conditions. Lastly, we present the latest advancements in TREPR technology developed in our laboratory, specifically ultrawide single-sideband phase-sensitive detection (U-PSD) TREPR, highlighting its significant impact and tremendous potential in advancing free radical chemistry research. We envision promising future applications of TREPR and its pivotal role in enhancing our understanding of mechanisms involved in complex radical processes and photocatalysis.

关键词： Time-resolved electron paramagnetic resonance (TREPR) Ultrawide single-sideband phase-sensitive detection (U-PSD) Spin chemistry Radical chemistry Photochemistry SPECTROSCOPY ABSORPTION EPR SPECTROMETER POLARIZATION INSIGHT CIDEP

Jiangsen Mao:a pioneer in Chinese hepatitis A vaccine and interferon research,a virologist at the forefront of times

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Protein & Cell 2024年第1期15卷 1-5页

作者： Huan Liu Kunlan Zuo Zongzhen wu hao Cheng University of Science and Technology of China Hefei 230026China State Key Laboratory of Virology Wuhan 430072China Institute of Microbiology Chinese Academy of SciencesBeijing 100101China

There is a renowned virologist who dedicated his life to virology and medicine *** has made important contributions to the study of Chinese polio and hepatitis A vaccines,interferons,and the theory of viral reverse *** invented a live attenuated vaccine for hepatitis A(H2 strain)in the late 1970s,which contributed to the prevention of hepatitis A epidemics in China and earned him the title"Hepatitis A Eradicator"He said.

关键词： prevention hepatitis vaccine

Depositional model of the Member Deng-2 marginal microbial mound-bank complex of the Dengying Formation in the southwestern Sichuan Basin, SW China: Implications for the Ediacaran microbial mound construction and hydrocarbon exploration

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Petroleum Science 2024年第2期21卷 806-822页

作者： Jin-Min Song Xin Jin Zhong Luo Shu-Gen Liu Shao-Bo Liu Xing-zhi Ma zhi-wu Li Xue-Song Lu Ling-Li Zhao Ke-Ran Li Jia-Xin Ren Li-Zhou Tian hao-Shuang Deng State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu610059SichuanChina PetroChina Research Institute of Petroleum Exploration and Development Beijing100083China Xihua University Chengdu610039SichuanChina

Recent advances in hydrocarbon exploration have been made in the Member Deng-2 marginal microbial mound-bank complex reservoirs of the Dengying Formation in the western Sichuan Basin, SW China,where the depositional process is regarded confusing. The microfacies, construction types, and depositional model of the Member Deng-2 marginal microbial mound-bank complex have been investigated using unmanned aerial vehicle photography, outcrop section investigation, thin section identification,and seismic reflections in the southwestern Sichuan Basin. The microbialite lithologic textures in this region include thrombolite, dendrolite, stromatolite, fenestral stromatolite, spongiostromata stone,oncolite, aggregated grainstone, and botryoidal grapestone. Based on the comprehensive analysis of“depositional fabrics-lithology-microfacies”, an association between a fore mound, mound framework,and back mound subfacies has been proposed based on water depth, current direction, energy level and lithologic assemblages. The microfacies of the mound base, mound core, mound flank, mound cap, and mound flat could be recognized among the mound framework subfacies. Two construction types of marginal microbial mound-bank complex have been determined based on deposition location, mound scale, migration direction, and sedimentary facies association. Type Jinkouhe microbial mound constructions(TJMMCs) develop along the windward margin owing to their proximity to the seaward subfacies fore mound, with a northeastwardly migrated microbial mound on top of the mud mound,exhibiting the characteristics of large-sized mounds and small-sized banks in the surrounding area. Type E'bian microbial mound constructions(TEMMCs) primarily occur on the leeward margin, resulting from the presence of onshore back mound subfacies, with the smaller southwestward migrated microbial mounds existing on a thicker microbial flat. The platform margin microbial mound depositional model can be correlated with certain late

关键词： Sichuan Basin The Member Deng-2 Marginal microbial mound-bank complex Depositional model Exploration implications