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Current trends and hotspots of depressive disorders with colorectal cancer:A bibliometric and visual study

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3687-3704页

作者： Zi-wei Yan Ying-Nan Liu Qian Xu yuan yuan Tumor Etiology and Screening Department of Cancer Institute and General Surgery The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Key Laboratory of Cancer Etiology and Prevention in Liaoning Education Department The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Laboratory of GI Cancer Etiology and Prevention in Liaoning Province The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Depression is strongly associated with colorectal cancer(CRC).Few bibliometric analyses have systematically summarized the research focus and recent progress in this *** To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between CRC and *** Articles on depression in CRC patients were collected from the Web of Science Core *** and VOSviewer software were used to visualize bibliometric *** From 2001 to 2022,Supportive Care in Cancer,the United States,Tilburg University,and Mols were the most productive and influential journal,country,institution,and author ***-occurrence cluster analysis of keywords placed quality of life,anxiety,and psychological stress in the center of the visual network *** clustering was performed for the clusters with studies of the relevant mechanism of action,which showed that:(1)Cytokines have a role essential for the occurrence and development of depressive disorders in CRC;(2)MicroRNAs have a role essential for the development of depressive disorders in CRC;(3)Some anticancer drugs have pro-depressant activity;and(4)Selective serotonin reuptake inhibitors have both antitumor and antidepressant *** Life quality and psychological nursing of the cancer population were key *** roles of cytokines and microRNAs,the pro-depression activity of anticancer drugs and their antitumor properties deserve in-depth study.

关键词： Depression Colorectal cancer Bibliometric analysis Cytokines Drugs Mechanism

Role of gut microbiota in Crohn’s disease pathogenesis:Insights from fecal microbiota transplantation in mouse model

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World Journal of Gastroenterology 2024年第31期30卷 3689-3704页

作者： Qiang Wu Lian-Wen yuan Li-Chao Yang Ya-wei Zhang Heng-Chang Yao Liang-Xin Peng Bao-Jia Yao zhi-Xian Jiang Geriatric Surgery of Department of General Surgery The Second Xiangya HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina

BACKGROUND Inflammatory bowel disease,particularly Crohn’s disease(CD),has been associated with alterations in mesenteric adipose tissue(MAT)and the phenomenon termed“creeping fat”.Histopathological evaluations showed that MAT and intestinal tissues were significantly altered in patients with CD,with these tissues characterized by inflammation and *** To evaluate the complex interplay among MAT,creeping fat,inflammation,and gut microbiota in *** Intestinal tissue and MAT were collected from 12 patients with *** manifestations and protein expression levels were analyzed to determine lesion *** samples were collected from five recently treated CD patients and five control subjects and transplanted into *** intestinal and mesenteric lesions in these mice,as well as their systemic inflammatory status,were assessed and compared in mice transplanted with fecal samples from CD patients and control *** Pathological examination of MAT showed significant differences between CDaffected and unaffected colons,including significant differences in gut microbiota *** microbiota transplantation(FMT)from clinically healthy donors into mice with 2,4,6-trinitrobenzene sulfonic acid(TNBS)-induced CD ameliorated CD symptoms,whereas FMT from CD patients into these mice exacerbated CD ***,FMT influenced intestinal permeability,barrier function,and levels of proinflammatory factors and ***,FMT from CD patients intensified fibrotic changes in the colon tissues of mice with TNBS-induced *** Gut microbiota play a critical role in the histopathology of *** MAT and creeping fat may therefore have potential in the treatment of patients with CD.

关键词： Mesenteric adipose tissue Crohn’s disease Fecal microbiota transplantation Intestinal fibrosis Intestinal barrier

Self-initiated static-dynamic state transition behavior and triggering mechanism of strain rockburst using three-dimensional discrete element method

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Underground Space 2024年第3期16卷 143-163页

作者： yuan Qian Cheng Zhao Rui wei Rui Zhang Lin Huang Huiguan Chen Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Tongji UniversityShanghai 200092China School of Engineering Tibet UniversityLhasaTibet850000China

The accurate understanding of rockburst mechanism poses a global challenge in the field of rock *** for strain rockburst,achieving self-initiated static-dynamic state transition is a crucial step in the formation of catastrophic ***,the state transition behavior and its impact on rockburst have not received sufficient attention,and are still poorly ***,this study specifically focuses on the state transition behavior,aiming to investigate its abrupt transition process and formation mechanism,and triggering effects on *** facilitate the study,a novel burst rock-surrounding rock combined laboratory test model is proposed and its effectiveness is validated through experiment ***,corresponding numerical models are established using the three-dimensional(3D)discrete element method(DEM),enabling successful simulation of static brittle failure and rockbursts of varying intensities under quasi-static displacement loading ***,through secondary development,comprehensive recording of the mechanical and energy information pertaining to the combined specimen system and its subsystems is *** a result of numerical investigation studies,the elastic rebound dynamic behavior of the surrounding rock was discovered and identified as the key factor triggering rockburst and controlling its *** impact loading on the burst rock,induced by elastic rebound,directly initiates the dynamic processes of rockburst,serving as the direct ***,the transient work and energy convergence towards the burst rock resulting from elastic rebound are recognized as the inherent cause of ***,it has been observed that a larger extent of surrounding rock leads to a stronger elastic rebound,thereby directly contributing to a more intense *** findings can provide novel theoretical insights for the exploring of rockburst mechanism and the development of monitoring and

关键词： Strain rockburst Static-dynamic state transition Self-initiation Triggering mechanism Elastic rebound Discrete element method

Galvanostatic method assembled ZIFs nanostructure as novel nanozyme for the glucose oxidation and biosensing

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Chinese Chemical Letters 2024年第9期35卷 279-283页

作者： Erzhuo Cheng Yunyi Li wei yuan wei Gong Yanjun Cai yuan Gu Yong Jiang Yu Chen Jingxi Zhang Guangquan Mo Bin Yang The Fourth Affiliated Hospital of Guangzhou Medical University School of Biomedical EngineeringGuangzhou Medical UniversityGuangzhou 511436China Department of Nephrology First Affiliated Hospital of Jinan UniversityGuangzhou 510630China Department of Oncology Xiangyang Central Hospital of Hubei University of Arts and ScienceXiangyang 441000China

Recently,the composite of soft conductive substrates,such as carbon fiber(CF),with metal-organic frameworks(MOFs)has been employed in a myriad of *** composite material has demonstrated exceptional potential in the realm of electrochemical sensing ***,the rapid growth of MOFs on the surface of CF remains a ***,we propose a simple galvanostatic method as an effective strategy for rapidly growing zeolitic imidazolate frameworks(ZIFs)on CF,and obtain nanocaltrop-like ZIFs modified CF(NC-ZIFs/CF)glucose(Glu)sensor platform with distinctive *** prepared NC-ZIFs/CF demonstrated significant electrocatalytic activity towards the oxidation of Glu in alkaline media,characterized by a pronounced augmentation in oxidation current *** an applied potential of 0.4 V,NC-ZIFs/CF exhibited a remarkably broad detection range(3–30,000μmol/L)and demonstrated outstanding selectivity,repeatability and ***,the NC-ZIFs/CF was efficaciously employed for the detection of blood Glu levels in the serum of both normoglycemic and hyperglycemic patients,obtaining highly reliable *** work demonstrates the feasibility of using galvanostatic method assembly to induce the growth of MOFs on conductive substrates,providing new ideas for electrocatalysis sensors and other electrochemical applications.

关键词： Sensor MOFs Electrocatalytic oxidation Electrochemical assembly Glucose

Design and Implementation of an Information System for Grassland Soil Management

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Agricultural Science & Technology 2010年第Z2期 191-193页

作者： wei zhi-yuan,QI zhi-ping Tropical Crops Genetic Resources Institute,Chinese Academy of Tropical Agricultural Sciences,Danzhou 571737

With grassland as the object of study,we briefly described the significance,main functions,characteristics and the implementation methods of spatial database and attribute database for grassland soil management information system and analyzed the systematical functional *** on this we hold that establishment of this system can not only provide reference information for the decision-making government departments involving in the pasture industrialization system management but also provide guidance for grassland operators to intentionally choose variety and to scientifically fertilize.

关键词： Grassland Soil Information system

Efficient piezo-assisted near-infrared-light-driven Cr(Ⅵ)reduction over Bi_(2)S_(3) nanowires transformed from ultrathin Bi_(2)WO_(6) nanosheets

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Rare Metals 2024年第9期43卷 4333-4343页

作者： Qiang Zhang yuan-Hao Cheng wei Liu Hui-Nan Che Yan-Hui Ao Key Laboratory of Integrated Regulation and Resource Development On Shallow Lakes Ministry of EducationCollege of EnvironmentHohai UniversityNanjing 210098China

The utilization of piezo-photocatalytic technol ogy for environmental remediation under full spectrum solar light is promising but still ***,one dimensional Bi_(2)S_(3)nanowires,which can utilize both mechanical energy and near-infrared(NIR)light to remov hexavalent chromium(Cr(Ⅵ))efficiently,were synthe sized by a restrained growth *** reaction rat constants of Cr(Ⅵ)reduction in piezo-photocatalyti process under NIR(800–2500 nm)reached 0.334 min^(-1)which were 3.2 and 12.4 times as that of single piezo and photocatalytic *** formation of polarized electri fields and one-dimensional structure allow ultrafast sepa ration of charge carriers,thereby promoting the catalyti ***,due to the strong penetrability o NIR light,the piezo-photocatalysis performance in turbid solutions under NIR light(0.188 min^(-1))was even com parable to that under visible light(0.186 min^(-1)).Thi study provides a new concept on the development of piezo photocatalytic technology for environmental remediation by utilization of NIR light and natural mechanical energy.

关键词： Piezo-photocatalysis NIR light Bi_(2)S_(3)nanowires Cr(Ⅵ)

A low-profile dual-broadband dual-circularly-polarized reflectarray for K-/Ka-band space applications

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Frontiers of Information Technology & Electronic Engineering 2024年第8期25卷 1145-1161页

作者： Xuanfeng TONG zhi Hao JIANG yuan LI Fan WU Lin PENG Taiwei YUE wei HONG State Key Laboratory of Milimeter Waves School of Information Science and EngineeringSoutheast UniversityNanjing 210096China Purple Mountain Laboratories Nanjing 21lllChina State Key Laboratory of Mobile Network and Mobile Multimedia Technology ZTE CorporationShenzhen 518057China Apple Inc. One Apple Park WayCupertinoCA 95014USA

A low-profile dual-broadband dual-circularly-polarized(dual-CP)reflectarray(RA)is proposed and demonstrated,supporting independent beamforming for right-/left-handed CP waves at both K-band and *** functionality is achieved by incorporating multi-layered phase shifting elements individually operating in the K-and Ka-band,which are then interleaved in a shared aperture,resulting in a cell thickness of only about *** rotating the designed K-and Ka-band elements around their own geometrical centers,the dual-CP waves in each band can be modulated *** reduce the overall profile,planar K-/Ka-band dual-CP feeds with a broad band are designed based on the magnetoelectric dipoles and multi-branch hybrid *** planar feeds achieve bandwidths of about 32%and 26%at K-and Ka-band respectively with reflection magnitudes below-13 dB,an axial ratio smaller than 2 dB,and a gain variation of less than 1 dB.A proof-of-concept dual-band dual-CP RA integrated with the planar feeds is fabricated and characterized which is capable of generating asymmetrically distributed dual-band dual-CP *** measured peak gain values of the beams are around 24.3 and 27.3 dBic,with joint gain variation<1 dB and axial ratio<2 dB bandwidths wider than 20.6%and 14.6%at the lower and higher bands,*** demonstrated dual-broadband dual-CP RA with four degrees of freedom of beamforming could be a promising candidate for space and satellite communications.

关键词： Broadband Dual-band Dual-circularly-polarized Reflectarray Shared-aperture

A multi-mechanism numerical simulation model for CO_(2)-EOR and storage in fractured shale oil reservoirs

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Petroleum Science 2024年第3期21卷 1814-1828页

作者： yuan-Zheng Wang Ren-Yi Cao zhi-Hao Jia Bin-Yu Wang Ming Ma Lin-Song Cheng College of Petroleum Engineering China University of Petroleum(Beijing)Beijing102249China John&Willie Leone Department of Energy&Mineral Engineering The Pennsylvania State UniversityUniversity Park16802PA.USA

Under the policy background and advocacy of carbon capture,utilization,and storage(CCUS),CO_(2)-EOR has become a promising direction in the shale oil reservoir *** multi-scale pore structure distribution and fracture structure lead to complex multiphase flow,comprehensively considering multiple mechanisms is crucial for development and CO_(2) storage in fractured shale *** this paper,a multi-mechanism coupled model is developed by *** to the traditional Eclipse300 and MATLAB Reservoir Simulation Toolbox(MRST),this model considers the impact of pore structure on fluid phase behavior by the modified Peng—Robinson equation of state(PR-EOS),and the effect simultaneously radiate to Maxwell—Stefan(M—S)diffusion,stress sensitivity,the nano-confinement(NC)***,a modified embedded discrete fracture model(EDFM)is used to model the complex fractures,which optimizes connection types and half-transmissibility calculation approaches between non-neighboring connections(NNCs).The full implicit equation adopts the finite volume method(FVM)and Newton—Raphson iteration for discretization and *** model verification with the Eclipse300 and MRST is *** results show that the interaction between the mechanisms significantly affects the production performance and storage *** effect of molecular diffusion may be overestimated in oil-dominated(liquid-dominated)shale *** well spacing and injection gas rate are the most crucial factors affecting the production by sensitivity ***,the potential gas invasion risk is *** model provides a reliable theoretical basis for CO_(2)-EOR and sequestration in shale oil reservoirs.

关键词： CO_(2)-EOR CO_(2)storage Shale oil reservoir Complex fracture model Multiple mechanisms

Structural control of magnetic nanoparticles for positive nuclear magnetic resonance imaging

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NUCLEAR SCIENCE AND TECHNIQUES 2024年第10期35卷 1-12页

作者： Ali, Zulaikha Zhang, Yunfei Kaul, Michael G. Truong, Billy Bhanot, Deepika Adam, Gerhard Li, yuan-yuan wei, He Calif State Univ Dept Chem & Biochem Fresno CA 93740 USA Univ Med Ctr Hamburg Eppendorf Ctr Radiol & Endoscopy Dept Diagnost & Intervent Radiol & Nucl Med D-20246 Hamburg Germany Oak Ridge Natl Lab Chem Sci Div Oak Ridge TN 37831 USA

In addition to the tens of millions of medical doses consumed annually around the world, a vast number of nuclear magnetic resonance imaging (MRI) contrast agents are being deployed in MRI research and development, offering precise diagnostic information, targeting capabilities, and analyte sensing. Superparamagnetic iron oxide nanoparticles (SPIONs) are notable among these agents, providing effective and versatile MRI applications while also being heavy-metal-free, bioconjugatable, and theranostic. We designed and implemented a novel two-pronged computational and experimental strategy to meet the demand for the efficient and rigorous development of SPION-based MRI agents. Our MATLAB-based modeling simulation and magnetic characterization revealed that extremely small maghemite SPIONs in the 1-3 nm range possess significantly reduced transversal relaxation rates (R-2) and are therefore preferred for positive (T-1-weighted) MRI. Moreover, X-ray diffraction and X-ray absorption fine structure analyses demonstrated that the diffraction pattern and radial distribution function of our SPIONs matched those of the targeted maghemite crystals. In addition, simulations of the X-ray near-edge structure spectra indicated that our synthesized SPIONs, even at 1 nm, maintained a spherical structure. Furthermore, in vitro and in vivo MRI investigations showed that our 1-nm SPIONs effectively highlighted whole-body blood vessels and major organs in mice and could be cleared through the kidney route to minimize potential post-imaging side effects. Overall, our innovative approach enabled a swift discovery of the desired SPION structure, followed by targeted synthesis, synchrotron radiation spectroscopic studies, and MRI evaluations. The efficient and rigorous development of our high-performance SPIONs can set the stage for a computational and experimental platform for the development of future MRI agents.

关键词： Magnetic nanoparticles Structure control Nuclear magnetic resonance imaging Modeling simulation X-ray absorption fine structure IRON-OXIDE NANOPARTICLES TRANSVERSE RELAXATION NMR SIGNAL PARTICLES BEHAVIOR TISSUES SPHERES