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Blimp-1 protein and Hans classification on prognosis of diffuse large B-cell lymphoma and their interrelation

Chinese Journal of Cancer 2010年第9期29卷 781-786页

作者： Yan song zhi cao Ling Li Hong-Tu Zhang Xun Zhang Department of Pathology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing100021 P. R. China

Background and Objective:Diffuse large B-cell lymphoma (DLBCL), the most common type of non-Hodgkin's lymphoma (NHL), is heterogeneous on molecular and clinical levels, therefore, its prognosis is difficult to *** study aimed to evaluate the value of Blimp-1 protein and Hans classification in predicting the prognosis of DLBCL and their ***:The clinical records of 136 patients with DLBCL were *** patients were followed up for 5-80 months (median, 39 months).Immunohistochemical staining for CD10, MUM1, Bcl-6, and Blimp-1 were performed on paraffin-embedded tumor tissues from the 136 *** correlations of Blimp-1 protein and Hans classification in prognosis of DLBCL and their interrelation were ***:Blimp-1 was detected in 38 (30.0%) patients, and was associated with a significantly shorter overall survival (OS) (P=0.030).Using the Hans classification based upon the expression of CD10, Bcl-6, and MUM1, 54 patients had germinal center B-cell (GCB) phenotype and 82 had non-GCB *** 5-year OS rate was 75% in the GCB group and 52% in the non-GCB group (P=0.020).The positive rate of Blimp-1 was 22.2% in the GCB group and 31.7% in the non-GCB group (P=0.329).The Cox regression multivariate analysis showed that international prognosis index (IPI) and Hans classification had independent prognostic significance, whereas Blimp-1 was not an independent prognostic ***:The patients with GCB subtype of DLBCL had better prognosis than the non-GCB *** level of Blimp-1 expression in the patients with DLBCL implies a shorter survival, but it is not associated with Hans classification.

关键词： B细胞淋巴瘤分类价值弥漫性预后飞艇蛋白发电机断路器免疫组织化学染色

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Long-term analysis of clear nights using satellite data considering astronomical sites in western China

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Research in Astronomy and Astrophysics 2020年第6期20卷 96-108页

作者： Zi-Huang cao Li-Yong Liu Yong-Heng Zhao Lu Feng Hugh RAJones Huang Shen Jin-Xin Hao Yan-Jie Xue Yong-Qiang Yao Jing Xu Ali Esamdin Zhao-Xiang Qi Jian-Rong Shi Jian Li Yuan Tian Zheng Wang Tai-Sheng Yan Xia Wang Jian-Ping Xiong Si-Cheng Yu Jun-Bo Zhang zhi-Xia Shen Yun-Ying Jiang Jia Yin Guang-Xin Pu Peng Wei Chun-Hai Bai Guo-Jie Feng Lu Ma Teng-Fei song Jian-Feng Wang Jian-Feng Tian Xian-Qun Zeng zhi-Gang Hou Shi-Long Liao zhi-song cao Dong-Wei Fan Yun-Fei Xu Chang-Hua Li Yi-Han Tao National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Centre for Astrophysics University of HertfordshireHatfieldUK School of Journalism.Communication University of China Beijing 100024China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

A large ground-based optical/infrared telescope is being planned for a world-class astronomical site in *** cloud-free night percentage is the primary meteorological consideration for evaluating candidate *** data from GMS and NOAA satellites and the MODIS instrument were utilized in this research,covering the period from 1996 to *** data analysis benefits from overlapping results from different independent teams as well as a uniform analysis of selected sites using GMS+NOAA *** significant ground-based monitoring is needed to validate these findings,we identify three different geographical regions with a high percentage of cloud-free conditions(~83%on average),which is slightly lower than at Mauna Kea and Cerro Armazones(~85%on average)and were chosen for the large international projects TMT and ELT *** study finds evidence that cloud distributions and the seasonal changes affected by the prevailing westerly winds and summer monsoons reduce the cloud cover in areas influenced by the *** is consistent with the expectations from climate change models and is suggestive that most of the identified sites will have reduced cloud cover in the future.

关键词： methods statistical-site testing-atmospheric effects-MODIS

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语言型EWAA算子的目标战场价值评估

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火力与指挥控制 2008年第7期33卷 81-83页

作者：王瑜陈志军宋志操桂林空军学院广西桂林541003

从发现的多个目标中确定打击顺序,取决于各目标的战场价值。通过定义模糊语言形式的评估标度及其运算,采用语言型EWAA算子对模糊语言偏好信息进行了集结,从而对目标战场价值进行评估,符合战场环境的复杂性和人们思维的模糊性,使指挥决... 详细信息

从发现的多个目标中确定打击顺序,取决于各目标的战场价值。通过定义模糊语言形式的评估标度及其运算,采用语言型EWAA算子对模糊语言偏好信息进行了集结,从而对目标战场价值进行评估,符合战场环境的复杂性和人们思维的模糊性,使指挥决策更加快速、准确。实例证明模型有效,计算简单。

关键词：语言型EWAA算子目标价值语言标度

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Data processing and data products from 2017 to 2019 campaign of astronomical site testing at Ali,Daocheng and Muztagh-ata

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Research in Astronomy and Astrophysics 2020年第6期20卷 109-130页

作者： Zi-Huang cao Jin-Xin Hao Lu Feng Hugh RAJones Jian Li Jing Xu Li-Yong Liu Teng-Fei song Jian-Feng Wang Hua-Lin Chen Yan-Jie Xue Huang Shen Yong-Heng Zhao Zhao-Xiang Qi Jian-Rong Shi Yuan Tian Zheng Wang Xia Wang Jin-Liang Hou Jin-Ming Bai Ji Yang Xu Zhou Yong-Qiang Yao Jia Yin Ali Esamdin Guang-Xin Pu Peng Wei Chun-Hai Bai Guo-Jie Feng Lu Ma Xuan Zhang Yu Liu Chong Pei zhi-Xia Shen Yun-Ying Jiang Jian-Feng Tian Xian-Qun Zeng zhi-Gang Hou Xu Yang Jun-Bo Zhang Shi-Long Liao Dong-Wei Fan Yun-Fei Xu Jian-Ping Xiong Tai-Sheng Yan Xi Zhang Chang-Hua Li Yi-Han Tao Si-Cheng Yu zhi-song cao Hong-Shuai Wang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Centre for Astrophysics University of HertfordshireHatfieldUK School of Journalism Communication University of ChinaBeijing 100024China Nanjing Institute of Astronomical Optics&Technology Chinese Academy of SciencesNanjing 210042China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210033China Beijing Kaiyang Space Technology Co. LtdBeijing 100085China

Based on previous site testing and satellite cloud data,Ali,Daocheng and Muztagh-ata have been selected as candidate sites for the Large Optical/Infrared Telescope(LOT) in *** present the data collection,processing,management and quality analysis for our site testing based on using similar *** analyze meteorological data,seeing,background light,cloud and precipitable water vapor data from 2017 March 10 to 2019 March *** also investigated the relative usefulness of our all-sky camera data in comparison to that from the meteorological TERRA satellite data based on a night-by-night comparison of the correlation and consistency between *** find a 6% discrepancy arising from a wide range of factors.

关键词： LOT Site-selection-data processing

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Universal design of three-dimensional porous graphene-iron based promotors for kinetically rationalized lithium-sulfur chemistry

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Journal of Energy Chemistry 2025年第1期100卷 192-200页

作者： Hua Gao Yunfeng Zhang Menglei Wang Ruoxuan Yang Shuai Feng Xuan cao Yaping Zhang Zhongyuan Lu Yingze song State Key Laboratory of Environment-Friendly Energy Materials School of Materials and Chemistry Southwest University of Science and Technology School of Material Science and Engineering Henan University of Technology College of Chemistry and Chemical Engineering Taishan University

Lithium-sulfur （Li-S） batteries are widely deemed to be one of the most potential candidates for future secondary batteries because of their remarkable energy ***,notorious polysulfide shuttling and retarded sulfur reaction kinetics pose significant obstacles to the further application of Li-S *** rationally designed highly active electrocatalysts can facilitate polysulfide conversion,the universal and scalable synthesis strategies need to be ***,a universal synthetic strategy to construct a series of three-dimensional （3D） porous graphene-iron （3DGr-Fe） based electrocatalysts involving 3DGr-FeP,3DGr-Fe3C,and 3DGr-Fe3Se4is exploited for manipulating the Li-S redox *** has been observed that the implementation of a 3D porous Gr architecture leads to the well-designed conductive networks,while the uniformly dispersed iron nanoparticles introduce an abundance of active sites,fostering the lithium polysulfide conversion,thereby bolstering the overall electrochemical *** Li-S battery with the 3DGr-Fe based electrocatalyst exhibits remarkable capacity retention of 94.8%upon 100 times at 0.2 ***,the soft-packaged Li-S pouch cell based on such a 3DGr-Fe electrocatalyst delivers superior capacity of 1060.71 mA h g-1and guarantees for the continuous 30 min work of fan *** investigation gives comprehensive insights into the design,synthesis,and mechanism of 3DGr-Fe based electrocatalysts with high activity toward efficient and durable Li-S batteries.

关键词： Lithium-sulfur battery Universal synthesis 3D graphene-iron based promotor Electrocatalysis

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Discrete Numerical Study on Type II Fracture of Partially Detached Concrete Panels in Cold Region

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Structural Durability & Health Monitoring 2025年第1期19卷 167-191页

作者： Huayi Zhang Maobin song Lei Shen Nizar Faisal Alkayem Maosen cao College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing210024China Haihe River Huaihe River and Xiaoqinghe River Basin Water Conservancy Management and Service Center of Shandong ProvinceJinan250100China College of Mechanics and Engineering Science Hohai UniversityNanjing211100China

When the upper chord beam of the beam-string structure(BSS)is made of concrete-ﬁlled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the *** order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during con-struction,the inﬂuence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefﬁcient on the bending stiffness are analyzed parametrically by the numerical simula-tion technology based on an actual *** calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical ***,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction ***,the optimal construction plan of concrete placementﬁrst and then prestress-tensioning is proposed.

关键词： Beam-string structure(BSS) concrete-ﬁlled steel tube(CFST) bending stiffness timing of concrete placement prestress-tensioning

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信息能力的三维定量分析

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指挥控制与仿真 2006年第5期28卷 19-21页

作者：刘烈锋宋志操陈志军桂林空军学院广西桂林541003

信息能力的定量分析对于科学地理解和把握信息优势和制信息权具有重要作用。通过对信息能力、信息优势和制信息权的科学界定,以感知态势与战场态势相比较,略去复杂的信息采集、处理和分发过程,对信息能力进行了三维定量分析,并给出以完... 详细信息

信息能力的定量分析对于科学地理解和把握信息优势和制信息权具有重要作用。通过对信息能力、信息优势和制信息权的科学界定,以感知态势与战场态势相比较,略去复杂的信息采集、处理和分发过程,对信息能力进行了三维定量分析,并给出以完备性、准确性和实时性构成的信息能力数学模型,说明了信息能力是完备性、准确性和实时性构成的三维体,其值落于[0,1]区间,据此对信息优势和制信息权进行了定量判断。

关键词：信息能力信息优势制信息权

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Optimizing the key parameter to accelerate the recovery of AMOC under a rapid increase of greenhouse gas forcing

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 39-45页

作者： Haolan Ren Fei Zheng Tingwei cao Qiang Wang International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina College of Oceanography Hohai UniversityNanjingChina CAS Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning Circulation(AMOC)plays a central role in long-term climate variations through its heat and freshwater transports,which can collapse under a rapid increase of greenhouse gas forcing in climate *** studies have suggested that the deviation of model parameters is one of the major factors in inducing inaccurate AMOC *** this work,with a low-resolution earth system model,the authors try to explore whether a reasonable adjustment of the key model parameter can help to re-establish the AMOC after its *** a new optimization strategy,the extra freshwater flux(FWF)parameter is determined to be the dominant one affecting the AMOC’s *** traditional ensemble optimal interpolation(EnOI)data assimilation and new machine learning methods are adopted to optimize the FWF parameter in an abrupt 4×CO_(2) forcing experiment to improve the adaptability of model parameters and accelerate the recovery of *** results show that,under an abrupt 4×CO_(2) forcing in millennial simulations,the AMOC will first collapse and then re-establish by the default FWF parameter ***,during the parameter adjustment process,the saltier and colder sea water over the North Atlantic region are the dominant factors in usefully improving the adaptability of the FWF parameter and accelerating the recovery of AMOC,according to their physical relationship with FWF on the interdecadal timescale.

关键词： Recovery of AMOC 4×CO_(2)forcing Key parameter Parameter estimation Data assimilation Machine learning

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Unraveling post-growth mechanisms of monolayer CsPbBr3 nanocubes:Laser-enhanced transformations and cathodoluminescence-electron microscopy correlations

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Journal of Energy Chemistry 2025年第1期100卷 146-156页

作者： Mingxing Li Xiaoge Wang Xiaofan cao zhiqun He Chunjun Liang Mingxing Chen Jing Ju Fangtian You Key Laboratory of Luminescence and Optical Information Ministry of Education Institute of Optoelectronic Technology Beijing Jiaotong University Beijing National Laboratory for Molecular Sciences (BNLMS) College of Chemistry and Molecular Engineering Peking University

Lead-halide perovskite nanoparticles（LHP NPs） are highly promising materials for next-generation displays and solid-state lighting due to their exceptional optical properties. However, their inherent instability presents a significant challenge. Recent advances have demonstrated that optoelectronic devices based on monolayer nanoparticle films exhibit both high luminescence efficiency and long-term *** research demonstrates that mobility limitations and anisotropic alignments in CsPbBr3nanocube monolayer films are key to their stabilization, hindering spontaneous growth through face-to-face fusion and resulting in the formation of connecting necks in a diagonal direction. Introducing laser irradiation confirmed this by significantly accelerating nanocubes growth, increasing mobility, and enhancing local structural ordering, leading to larger and more regularly shaped nanosheets. Fourier transform infrared spectroscopy and energy dispersive spectroscopy line-scan analyses indicated that laser irradiation did not disrupt the ligand structure. Transmission electron microscopy and correlative cathodoluminescence electron microscopy revealed the effects of post-growth and heterogeneous structures, including enhanced luminescence and inhomogeneous intensity in the nanosheets. These findings deepen the understanding of the post-growth mechanism of monolayer nanoparticles and the structure-emission correlation and highlight the unique role of laser irradiation in directing the formation of well-defined and regular nanostructures.

关键词： Post-growth mechanism Heterogeneous structure Single-particle spectroscopy Laser irradiation

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Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi Xu Junqiu Jia Rui Mao Xiang cao Yun Xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

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