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Journal of Pharmaceutical Analysis 2019年第4期9卷 266-273页

作者： Xin-Yue Chen San-Hu Gou zhi-qiang shi zhi-Yuan Xue shi-Lan Feng School of Pharmacy Lanzhou University

The traditional Chinese medicine of Radix Hedysari plays an important role in invigorating gas for ascending, benefiting blood for promoting production of fluid, and promoting circulation for removing obstruction in collaterals, which is consistent with the principle of treatment for osteoporosis. This study is designed to investigate the bioactive components on increasing peak bone mass (PBM) by exploring the spectrum-effect relationship between chromatography fingerprints and effect. Multiple indicators are selected to evaluate the pharmacological activity. In fingerprints, 21 common peaks are obtained, five of which are identified. Furthermore, gray relational analysis (GRA) is a quantitative method of gray system theory and is used to describe the correlation degree of common peaks and pharmacological activities with relational value. 21 components are then divided into three different regions, of which ononin and calycosin play an extremely significant role in increasing PBM. In addition, factor analysis and hierarchical cluster analysis (HCA) are used to screen the optimal producing area for Radix Hedysari. This provides a comprehensive and efficient method to improve the quality evaluation of Radix Hedysari, confirming the bioactive components for PBM-enhancement and further develop its medicinal value.

关键词： Factor analysis Gray relational analysis Hierarchical cluster analysis Peak bone mass Radix Hedysari Spectrum-effect relationship

Novel synthesis of N-substituted-calix[4]azacrown derivatives

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Chinese Chemical Letters 2010年第7期21卷 807-809页

作者： zhi qiang shi Ya Qing Feng Shu Xian Meng Renai College of Tianjin University Tianjin 301636China School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China

A novel series of calix[4]azacrown derivatives with the reaction between calix[4]azacrown and the different fluorophore derivatives,which may be useful fluorescent receptors,have been synthesized and structurally characterized by IR,~1H NMR,^（13）C NMR and *** their analysis data,it was found those compounds adopted a cone conformation.

关键词： Calixazacrown Naphthalimide Fluorescent sensors Synthesis Characterization

Synthesis and structure characterization of a novel series of N-alkylphthalimidylaminocarbonylmethoxylcalix[4]arenes

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Chinese Chemical Letters 2007年第12期18卷 1493-1495页

作者： zhi qiang shi Ya Qing Feng Bing Zhao Wen Xiang Wang School of Chemical Engineer and Technology Tianjin University Tianjin 300072 China

A novel series of N-alkylphthalimidylaminocarbonylmethoxylcalix[4]arenes with the reaction between 4-（N-bromoacetyla- mino）-phthalimide derivatives and calix[4]arene has been synthesized and structurally characteriz... 详细信息

关键词： Calixarene 4-(N-Bromoacetylamino)-phthalimide Fluorescent

Dual mechanisms of Bcl-2 regulation in IP_(3)-receptor-mediated Ca^(2+)release:A computational study

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Chinese Physics B 2021年第10期30卷 689-697页

作者： Hong Qi zhi-qiang shi zhi-Chao Li Chang-Jun Sun shi-Miao Wang Xiang Li Jian-Wei Shuai Complex Systems Research Center Shanxi UniversityTaiyuan 030006China Shanxi Key Laboratory of Mathematical Techniques and Big Data Analysis on Disease Control and Prevention Shanxi UniversityTaiyuan 030006China School of Mathematical Sciences Shanxi UniversityTaiyuan 030006China Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials Research Xiamen UniversityXiamen 361005China State Key Laboratory of Cellular Stress Biology Innovation Center for Cell Signaling Networkand National Institute for Data Science in Health and MedicineXiamen UniversityXiamen 361005China

Inositol 1,4,5-trisphosphate receptors(IP_(3)R)-mediated calcium ion(Ca^(2+))release plays a central role in the regulation of cell survival and ***-2 limits the Ca^(2+)release function of the IP3R through a direct or indirect ***,the two mechanisms are overwhelmingly complex and not completely ***,we convert the mechanisms into a set of ordinary differential *** firstly simulate the time evolution of Ca^(2+)concentration under two different levels of Bcl-2 for the direct and indirect mechanism models and compare them with experimental results available in the ***,we employ one-and two-parameter bifurcation analysis to demonstrate that Bcl-2 can suppress Ca^(2+)signal from a global point of view both in the direct and indirect mechanism *** then use mathematical analysis to clarify that the indirect mechanism is more efficient than the direct mechanism in repressing Ca^(2+)***,we predict that the two mechanisms restrict Ca^(2+)signal ***,our study provides theoretical insights into Bcl-2 regulation in IP_(3)R-mediated Ca^(2+)release,which may be instrumental for the successful development of therapies to target Bcl-2 for cancer treatment.

关键词： Ca^(2+) Bcl-2 bifurcation analysis oscillations

Synthesis and structure characterization of novel calix[4](aza)crown derivatives

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Chinese Chemical Letters 2007年第8期18卷 912-914页

作者： zhi qiang shi Ya Qing Feng Wen Xiang Wang He Wen Wang School of Chemical Engineer and Technology Tianfin University Tianjin 300072 China

Three novel calix[4]（aza）crown deravatives have been synthesized, including a new [2]pseudorotaxane in which calix[4]- azacrown behaves as a stopper, a novel ＇tren＇ type calix[4]azacrown and a novel ＇spiro＇ type... 详细信息

关键词： Calixazacrown Morpholine Pseudorotaxane

Expanded mesocarbon microbead cathode for sodium-based dual-ion battery with superior specific capacity and long-term cycling stability

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Rare Metals 2023年第5期42卷 1545-1556页

作者： Yu-Jia Wang Xue-Wen Yu Peng Zhang Zheng-Jie Wang Lei Yan Liang He Ze-Kai Wang zhi-qiang shi Tianjin Key Laboratory of Advanced Fibers and Energy Storage School of Materials Science and EngineeringTiangong UniversityTianjin300387China College of New Energy Ningbo University of TechnologyNingbo315211China

Dual-ion batteries(DIBs)have attracted tremendous attention owing to their high operating voltage and are considered promising candidates for low-cost clean energy storage ***,the decomposition of electrolytes and collapse of the cathode structure may lead to low Coulombic efficiency(CE)and low cycling stability of ***-layered electrode materials can accommodate the intercalation/deintercalation of large anions,which is believed to overcome these ***,expanded mesocarbon microbeads(200HRO-MCMB)possessing an enlarged interlayer spacing(0.405 nm)were prepared via modified Hummers and subcritical hydrothermal reduction *** the indispensable electrochemical activation,200HRO-MCMB(hydrothermal reduction at 200℃)exhibited a high specific capacity(120 mAh·g^(-1)at50 mA·g^(-1))when used as a cathode for a sodium-based DIB,and the CE significantly improved within the 2.0-4.5 V voltage ***,the cycling stability exceeded over 600 ***,this cathode possessed enlarged interlayers that decreased the barrier of PF6^(-)transport,and the battery storage mechanism corresponded to a transitioning state between double-layer capacitance and Faradaic ***,this work will expand the scope of the practical application of low-cost sodium-based DIBs.

关键词： Expanded mesocarbon microbeads Sodiumbased dual-ion batteries Interlayer spacing

Synthesis and Characterization of a Squarylium Cyanine Dye with Two [60]Fullerene Units

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Chinese Chemical Letters 2001年第8期12卷 683-686页

作者： Chi Min DU Ju Hua XU Yu Liang LI zhi qiang shi Shu WANG Dao Ben ZHU Center of Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100080

A new [60]fullerene dimer 2 in which two C-60 units are covalently attached to a squarylium cyanine dye has been synthesized and characterized.

关键词： Fullerene dimer squarylium cyanine dye

Change monitoring of earth rotation parameter with Maglev gyroscope precessional torque

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中国有色金属学会会刊：英文版 2011年第S3期21卷 589-593页

作者： YANG zhi-qiang, GONG Yun, shi Zhen, LI Yun Geological Engineering and Geomatics Institute, Chang’an University, Xi’an 710054, China Geological Engineering and Geomatics Institute Chang'an University Xi'an 710054 China

Through analyzing the relationship between gyro dynamic torques produced by the changes of earth rotation parameters (ERP), a method of measuring the earth rotation parameters was proposed and explored by using gyroscope. The preliminary experiments were carried out using GAT Maglev Gyro Station (which is self-developed by China). Considering the measurement and expanding-application of the earth rotation parameters, some ideas and opinions about the structure design, measurement methods and data processing of gyro were proposed, and some outlook of the expanding-application of the gyroscope in geodetic and geophysical fields were done. The experimental results show that using the high-precision gyroscope to determine the changes of ERP is feasible, with the emergence of ultra-high precision gyro; it is possible for determining the earth rotation parameters by gyro in stead of by current complex space surveying technology.

关键词： Maglev gyroscope earth rotation parameters (ERP) precessional torque pole motion length of day

Harmful evaluation of heavy metals from soil layer to the groundwater: Take the Jilin Hunchun Basin as an example

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China Geology 2024年第1期7卷 116-124页

作者： Xiao-Dong Guo qiang Liu Hui-Rong Zhang Xu-Fei shi Chuan-Yu Qin zhi-qiang Zhang Shenyang Geological Survey Center China Geological SurveyMinistry of Natural ResourcesShenyang 110034China Key Laboratory of Black Land Evolution and Ecological Effects Shenyang 110034China New Energy and Environment College Jilin UniversityChangchun 130026China Jilin Hydrogeological Survey Institute Changchun 130026China

The continuous enrichment of heavy metals in soils has caused potential harm to *** methods to evaluate the harm of heavy metals in soil to groundwater are lacked in previous *** on the theory of groundwater circulation and solid-liquid equilibrium,a simple and easy-touse flux model of soil heavy metals migrating to groundwater is *** on groundwater environmental capacity,an innovative method for evaluating the harm of heavy metals in soil to groundwater is proposed,which has been applied in Hunchun Basin,Jilin Province,*** results show that the fluxes of soil heavy metals into groundwater in the study area are Zn,Cu,As,Pb,Cd,Ni,and Hg in descending *** content of heavy metals in groundwater(As,Hg,Cu,Pb,Zn,Ni,and Cd)in most areas has not risen to the threshold of environmental capacity within 10 *** harm levels of soil heavy metals to groundwater in the most townships soils are at the moderate level or *** evaluation method can quantify the flux of soil heavy metals into groundwater simply and quickly,determine the residual capacity of groundwater to heavy metals,evaluate the harm level of soil heavy metals to groundwater,provide support for relevant departments to carry out environmental protection of soil and groundwater,and provide a reference to carry out similar studies for related scholars.

关键词： Soil heavy metals As+Hg+Cu+Pb+Zn+Ni+Cd Environmental capacity Groundwater Hazard degree Migration flux model Agricultural geological survey engineering Hunchun Basin Jilin Province

A comprehensive review on microchannel heat sinks for electronics cooling

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International Journal of Extreme Manufacturing 2024年第2期6卷 133-162页

作者： zhi-qiang Yu Mo-Tong Li Bing-Yang Cao Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua UniversityBeijing 100084People’s Republic of China

The heat generation of electronic devices is increasing dramatically,which causes a serious bottleneck in the thermal management of electronics,and overheating will result in performance deterioration and even device *** the development of micro-machining technologies,the microchannel heat sink(MCHS)has become one of the best ways to remove the considerable amount of heat generated by high-power *** has the advantages of large specific surface area,small size,coolant saving and high heat transfer *** paper comprehensively takes an overview of the research progress in MCHSs and generalizes the hotspots and bottlenecks of this *** heat transfer mechanisms and performances of different channel structures,coolants,channel materials and some other influencing factors are ***,this paper classifies the heat transfer enhancement technology and reviews the related studies on both the single-phase and phase-change flow and heat *** comprehensive review is expected to provide a theoretical reference and technical guidance for further research and application of MCHSs in the future.

关键词： microchannel heat sink thermal management of electronics microscale heat transfer heat transfer enhancement