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川汉铁路股款亏蚀问题与四川保路运动的演变

史学月刊 2024年第1期 36-46页

作者：高龙四川大学历史文化学院四川成都610200

川汉铁路自筹款开办以来就存在严重的股款亏蚀问题,累计银额达数百万两,四川州县租股局和成都川路总公司的当事路绅对之负有不可推卸的责任。为保护既得利益不被干涉和非法利益不被查处,成都路绅先后回避、拒绝和反对清廷的收路查账旨... 详细信息

川汉铁路自筹款开办以来就存在严重的股款亏蚀问题,累计银额达数百万两,四川州县租股局和成都川路总公司的当事路绅对之负有不可推卸的责任。为保护既得利益不被干涉和非法利益不被查处,成都路绅先后回避、拒绝和反对清廷的收路查账旨意及干路国有政策,同时还“打倒”了提出保款主张和附股方案的同乡京官。这些矛盾冲突背后的利益之争作为一大动因,直接推动了四川保路运动的兴起和高涨,也在一定程度上造就了其与湘、鄂、粤三省路事风潮的不同走向。

关键词：晚清川汉铁路四川保路运动股款亏蚀

Identification of the Alternative Promoters of the KChIP4 Subfamily

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Acta Biochimica et Biophysica Sinica 2005年第4期37卷 241-247页

作者： Xiao-Yun DENG Fang CAI Kun XIA Qian PAN zhi-gao long Ling-Qian WU De-Sheng LIANG He-Ping DAI Zhuo-Hua ZHANG Jia-Hui XIA National Laboratory of Medical Genetics,Central South University,Changsha 410078,China National Laboratory of Medical Genetics Central South University Changsha 410078 China

The subfamily of voltage-dependent potassium (Kv) channel interacting protein 4 (KChIP4)is made up of the auxiliary interacting protein of voltage-dependent potassium *** this study,thestructure of four splicing variants of the human KChIP4 gene was *** of the four isoforms ofthe KChIP4 gene,KChIP4.1,KChIP4.2 and KChIP4.4,were amplified from mouse and human fetal braintissues by reverse transcription-polymerase chain reaction and then *** on the bioinformaticsanalysis of the genomic sequences of the gene,we cloned and characterized two promoter fragments fromthe KChIP4 *** was a 325 bp fragment upstream of the 5’ end of the KChIP4.1 mRNA sequence andthe other was an 818 bp fragment located immediately at the 5’ end of the KChIP4.4 *** of themcan initiate the transcription of the reporter gene in HT1080 cells and Sprague-Dawley (SD) rat fetal brainneurons,and they contain C+G islands,except typical TATA boxes and CAAT *** shows that theKChIP4 gene expression is regulated by an alternative promoter.

关键词： splicing variant alternative promoter transcriptional regulation

Robotic-assisted low anterior resection for rectal cancer shows similar clinical efficacy to laparoscopic surgery: A propensity score matched study

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1558-1570页

作者： Shen-Xiang long Xin-Ning Wang Shu-Bo Tian Yu-Fang Bi Shen-Shuo gao Yu Wang Xiao-Bo Guo Department of Gastrointestinal Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Nursing The People’s Hospital of Zhangqiu AreaJinan 250200Shandong ProvinceChina Medical Center for Gastrointestinal Surgery Weifang People’s HospitalWeifang 261000Shandong ProvinceChina

BACKGROUND Rectal cancer ranks as the second leading cause of cancer-related mortality worldwide,necessitating surgical resection as the sole treatment *** the years,there has been a growing adoption of minimally invasive surgical techni-ques such as robotic and laparoscopic *** surgery represents an innovative modality that effectively addresses the limitations associated with traditional laparoscopic *** previous studies have reported favo-rable perioperative outcomes for robot-assisted radical resection in rectal cancer patients,further evidence regarding its oncological safety is still *** To conduct a comparative analysis of perioperative and oncological outcomes between robot-assisted and laparoscopic-assisted low anterior resection(LALAR)*** The clinical data of 125 patients who underwent robot-assisted low anterior resection(RALAR)and 279 patients who underwent LALAR resection at Shandong Provincial Hospital Affiliated to Shandong First Medical University from December 2019 to November 2022 were retrospectively *** performing a 1:1 propensity score matching,the patients were divided into two groups:The RALAR group and the LALAR group(111 cases in each group).Subsequently,a comparison was made between the short-term outcomes within 30 d after surgery and the 3-year survival outcomes of these two *** Compared to the LALAR group,the RALAR group exhibited a significantly earlier time to first flatus[2(2-2)d vs 3(3-3)d,P=0.000],as well as a shorter time to first fluid diet[4(3-4)d vs 5(4-6)d,P=0.001].Additionally,the RALAR group demonstrated reduced postoperative indwelling catheter time[2(1-3)d vs 4(3-5)d,P=0.000]and decreased length of hospital stay after surgery[5(5-7)d vs 7(6-8)d,P=0.009].Moreover,there was an observed increase in total cost of hospitalization for the RALAR group compared to the LALAR group[10777(10780-11850)dollars vs 10550(8766-11715)dollars,P=0.012].No signi

关键词： Rectal cancer Robotic surgical procedures Laparoscopy Low anterior resection Clinical efficacy

Effect of mesopore spatial distribution of HZSM-5 catalyst on zinc state and product distribution in 1-hexene aromatization

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Chinese Journal of Chemical Engineering 2024年第3期67卷 16-26页

作者： Chenhao Wei Di gao Guohao Zhang Liang Zhao Jinsen gao Chunming Xu The State Key Lab of Heavy Oil Processing China University of Petroleum(Beijing)Beijing 102249China SINOPEC Research Institute of Petroleum Processing Co. Ltd.Beijing 100083China

1-hexene aromatization is a promising technology to convert excess olefin in fluid catalytic cracking(FCC)gasoline to high-value benzene(B),toluene(T),and ***,the increasing market demand of xylene has put forward higher requirements for new generation of *** increasing xylene yield in 1-hexene aromatization,the effect of mesopore structure and spatial distribution on product distribution and Zn loading was *** with different mesopore spatial distribution were prepared by post-treatment of parent HZSM-5 zeolite,including NaOH treatment,tetra-propylammonium hydroxide(TPAOH)treatment,and *** was found the evenly distributed mesopore mainly prolongs the catalyst lifetime by enhancing diffusion properties but reduces the aromatics selectivity,as a result of damage of micropores close to the catalyst *** the selectivity of high-value xylene can be highly promoted when the mesopore is mainly distributed interior the ***,the state of loaded Zn was also affected by mesopores spatial *** the optimized catalyst,the xylene selectivity was enhanced by 12.4%compared with conventional Zn-loaded parent HZSM-5 catalyst at conversion over 99%.It was attributed to the synergy effect of mesopores spatial distribution and optimized acid *** work reveals the role of mesopores in different spatial positions of 1-hexene aromatization catalysts in the reaction process and the influence on metal distribution,as well as their synergistic effect two on the improvement of xylene selectivity,which can improve our understanding of catalyst pore structure and be helpful for the rational design of high-efficient catalyst.

关键词： 1-Hexene aromatization Alkali treatment Xylene selectivity Mesopores Zinc state

Impacts of central-Pacific El Niño and physical drivers on eastern Pacific bigeye tuna

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Journal of Oceanology and Limnology 2024年第3期42卷 972-987页

作者： Peng LIAN Le gao Key Laboratory of Ocean Observation and Forecasting and Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

Bigeye tuna Thunnus obesus is an important migratory species that forages deeply,and El Niño events highly influence its distribution in the eastern Pacific *** sea surface temperature is widely recognized as the main factor affecting bigeye tuna(BET)distribution during El Niño events,the roles of different types of El Niño and subsurface oceanic signals,such as ocean heat content and mixed layer depth,remain *** conducted A spatial-temporal analysis to investigate the relationship among BET distribution,El Niño events,and the underlying oceanic signals to address this knowledge *** used monthly purse seine fisheries data of BET in the eastern tropical Pacific Ocean(ETPO)from 1994 to 2012 and extracted the central-Pacific El Niño(CPEN)indices based on Niño 3 and Niño ***,we employed Explainable Artificial Intelligence(XAI)models to identify the main patterns and feature importance of the six environmental variables and used information flow analysis to determine the causality between the selected factors and BET ***,we analyzed Argo datasets to calculate the vertical,horizontal,and zonal mean temperature differences during CPEN and normal years to clarify the oceanic thermodynamic structure differences between the two types of *** findings reveal that BET distribution during the CPEN years is mainly driven by advection feedback of subsurface warmer thermal signals and vertically warmer habitats in the CPEN domain area,especially in high-yield fishing *** high frequency of CPEN events will likely lead to the westward shift of fisheries centers.

关键词： bigeye tuna central-Pacific El Niño(CPEN) ocean heat content Argo explainable artificial intelligence(XAI) information flow

The late Early-Paleozoic granitic magmatism in Northwestern Fujian, China: constraints on intraplate orogeny in the South China block

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Acta Geochimica 2024年第1期43卷 134-149页

作者： WanLi gao ZongXiu Wang Institute of Geomechanics Chinese Academy of Geological ScienceBeijing 100081People’s Republic of China Key Laboratory of Paleomagnetism and Tectonic Reconstruction of Ministry of Natural Resources Beijing 100081People’s Republic of China

The Early Paleozoic tectono-thermal event was a significant orogenic activity during the Phanerozoic era,which had a profound impact on the early crust of the South China Block(SCB) and established the foundation for later tectonic *** Wuyi-Yunkai orogenic belt in Southeastern China was extensively exposed to Early Paleozoic magmatism,the genetic mechanism of which remains *** shed light on this issue,detailed petrological,geochemical,and zircon U-Pb-Hf isotopic studies were carried out on two granitoids,namely the Yuntongshan pluton and the gaoqiao pluton,identified in the central *** U-Pb chronology of the Yuntongshan and gaoqiao bodies yielded ages of437±4 Ma(MSWD=2.2) and 404±2 Ma(MSWD=12),respectively,indicating that they were emplaced during the Early Silurian and Early Devonian *** granitoids are primarily composed of biotite-granite and biotite-monzonitic-granites,with high concentrations of S_(i)O_(2)(73.59-75.91 wt%),K_(2)O+Na_(2)O(8.31-8.73wt%),and low contents of MgO,CaO,Cr,*** are classified as high-K calc-alkaline and weakly metaluminous-strongly peraluminous S-type *** granitoids are enriched in light rare earth elements(LREEs) and large ion lithophile elements(LILEs) and depleted in heavy rare earth elements(HREEs) and high field strength elements(HFSEs) with arc *** εHf(t) values of-3.3 to-15.4 with two-stage Hf model ages ranging from 2829 to 1644 Ma,combined with the presence of Neoproterozoic inherited zircons,suggest that the primary magma of these granitoids was derived from the partial melting of Neoproterozoic crust with a Paleoproterozoic crustal model *** findings,combined with the spatio-temporal distribution of regional magmatism,reveal that the late Early-Paleozoic granitoids formed in the intraplate orogenic background originating from the subduction of the proto-Tethys Ocean and proto-Pacific Ocean around the margin of the east Gondwana supercontinent.

关键词： Late Early-Paleozoic Granites Intraplate orogeny Cathysian block Zircon U-Pb-Hf Isotopic composition

BambooBase:A comprehensive database of bamboo omics and systematics

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Molecular Plant 2024年第5期17卷 682-685页

作者： Yun-long Liu Shu-Yang gao Guihua Jin Meng-Yuan Zhou Qijuan gao Cen Guo Yi-Zhou Yang Liang-Zhong Niu Enhua Xia Zhen-Hua Guo Peng-Fei Ma De-Zhu Li Germplasm Bank of Wild Species&Yunnan Key Laboratory of Crop Wild Relatives Omics Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650201China State Key Laboratory of Tea Plant Biology and Utilization Anhui Agricultural UniversityHefeiAnhui 230036China School of Computer and Artificial Intelligence Hefei Normal UniversityHefeiAnhui 230061China Key Laboratory for Plant Diversity and Biogeography in East Asia Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China

Dear Editor,Bamboos(Bambusoideae,Poaceae)are of significant economic and ecological importance,supporting billions of people and contributing to international trade(Wu et al.,2023).They play a crucial role in carbon fixation and support a multitude of other species including the giant panda(Clark et al.,2015).Since the release of the first draft genome of moso bamboo(Phyllostachys edulis)(Peng et al.,2013),there has been a notable increase in the sequencing,assembly,and annotation of diverse bamboo genomes(Guo et al.,2019;Zheng et al.,2022;Ma et al.,2024).An existing resource for bamboo genomics,BambooGDB(Zhao et al.,2014),provides information based on the individual draft reference genome of moso *** is needed,however,is a resource reinforcing multiple genome assemblies in Bambusoideae to enable researchers to unravel the evolutionary history of chromosomes and genes through cladespecific comparative genomic ***,we present BambooBase(https://***/),a newly developed web-based database designed to provide a seamless user experience for bamboo omics and systematics.

关键词： enable supporting Bamboo

A novel relationship between elastic modulus and void ratio associated with principal stress for coral calcareous sand

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 1033-1048页

作者： Ran gao Jianhong Ye State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China

Elastic moduli,*** modulus G and bulk modulus K,are important parameters of geotechnical materials,which are not only the indices for the evaluation of the deformation ability of soils but also the important basic parameters for the development of the constitutive models of geotechnical *** this study,a series of triaxial loading-unloading-reloading shear tests and isotropic loading-unloadingreloading tests are conducted to study several typical mechanical properties of coral calcareous sand(CCS),and the void ratio evolution during loading,unloading and *** test results show that the stress-strain curves during multiple unloading processes are almost parallel,and their slopes are much greater than the deformation modulus at the initial stage of *** relationship between the confining pressure and the volumetric strain can be defined approximately by a hyperbolic equation under the condition of monotonic loading of confining *** the condition of confining pressure unloading,the evolution of void ratio is linear in the e-lnp0 plane,and these lines are a series of almost parallel lines if there are multiple processes of *** on the experimental results,it is found that the modified Hardin formulae for the elastic modulus estimation have a significant deviation from the tested values for *** on the experimental results,it is proposed that the elastic modulus of soils should be determined by the intersection line of two spatial surfaces in the G/K-e-p’/pa space(pa:atmosphere pressure).“Ye formulation”is further proposed for the estimation of the elastic modulus of *** new estimation formulation for soil elastic modulus would provide a new method to accurately describe the mechanical behavior of granular soils.

关键词： Coral calcareous sand(CCS) Elastic shear modulus Elastic bulk modulus Triaxial test Estimation formulation Ye formulation

Numerical simulation of fluid flow and free surface fluctuations during wheel and belt casting process

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Journal of Iron and Steel Research(International) 2024年第5期31卷 1117-1126页

作者： Kun gao Yan Peng National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao066004HebeiChina

The unstable fluid flow and severe free surface fluctuations in the wheel and belt caster can affect the quality of the cast *** lower level height tends to entrap inclusions in the molten *** the other hand,the higher level height makes the production process more dangerous due to the overflow of high temperature fluid from the mold.A computational model of the molten metal pouring process was *** transient fluid flow and free surface fluctuations behavior were calculated using the three-dimensional large eddy simulation model and the volume of fluid *** results show that the flow velocity of the main jet gradually decreases under the influence of the low kinetic energy fluid in the *** is an obvious oscillation in the tail of the jet,while the flow field is asymmetric in *** jet is closer to the inside radius side due to the Coanda effect,and there is a recirculation zone on the inside radius and the outside radius respectively,according to the 10 s time-averaged *** with the industrial observation and simulation results,the shape of the free surface is a wave that varies with *** addition,the free surface height is lowest and the flow velocity is highest in the region near the jet.

关键词： Fluid flow Free surface Wheel and belt caster Large eddy simulation Volume of fluid method