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Width Compensation and Correction for the Plan View Pattern Control Function on Plate Mill

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Journal of Harbin Institute of Technology(New Series) 2013年第5期20卷 31-35页

作者： zhi-jie jiao Chun-Yu He Zhong Zhao Jing-Guo Ding State Key Laboratory of Rolling and Automation Northeastern University

Research works on width compensation and correction were carried out in order to eliminate the effects of the PVPC （ plan view pattern control） on width accuracy of plate mill. The thickness correction calculation formula was derived for compensation the width deviation caused by PVPC function, and the formula is unified under the thinning and thickening conditions. In order to improve the width calculation accuracy, width spread calculation process was modified with dividing one large reduction pass to several small reduction calculation steps. The thickness wedge was simplified to rectangle based on the volume constant principle, and the width spread model for PVPC was constructed. The width compensation and correction for the PVPC functions are used for the online control process, and the Product dimension accuracy is improved. With the decrease of Crop losses, the Droduct yield was increased with 0. 2%.

关键词： Lplate mill plan view pattern control width correction and compensation width spread model

Osteoblastoma of the mandible：A case report

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中国口腔颌面外科杂志 2008年第B5期6卷 192-193页

作者： Xu zhi jie jiao Guo Hua Zhong Shi Chun Department Oral and Maxillofacial Surgery Hospital ofStomatology Guanghua College of Stomatology Sun Yat-SenUniversity. Guangzhou 510055 China

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan jiao Lingyan Meng Kang Du Xuezhi Li School of Mental Health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

Systematic comparison of Kawasaki disease Z-score formulas:Enhancing diagnostic accuracy and clinical applicability across populations

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World Journal of Clinical Pediatrics 2025年第1期14卷 63-68页

作者： Yan Pan Fu-Yong jiao Department of Pediatrics The First Affiliated Hospital of Yangtze UniversityJingzhou 434000Hubei ProvinceChina Shaanxi Kawasaki Disease Diagnosis and Treatment Center Children's HospitalShaanxi Provincial People's Hospital of Xi'anJiaotong UniveristyXi'an 710000Shaanxi ProvinceChina

This study aims to evaluate the performance of six distinct Z-score formulas in diagnosing coronary artery dilation in Kawasaki disease(KD)patients,with a focus on their clinical applicability across diverse populations.A retrospective analysis was conducted using comparative statistical methods to assess the sensitivity and specificity of each *** Kobayashi and Dallaire formulas demonstrated the highest sensitivity in China,particularly in younger patients with prolonged fever *** findings provide evidence-based recommend-ations for selecting Z-score formulas to optimize diagnostic precision in KD patients.

关键词： Kawasaki disease Early diagnosis Z-score Children

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian jiao Lai Xu Zhen Gu Hua Yan Dingding Shen Xiaosong Gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

Lipid droplets in the nervous system:involvement in cell metabolic homeostasis

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Neural Regeneration Research 2025年第3期20卷 740-750页

作者： Yuchen Zhang Yiqing Chen Cheng Zhuang Jingxuan Qi Robert Chunhua Zhao jiao Wang School of Life Sciences Shanghai UniversityShanghaiChina School of Medicine Shanghai UniversityShanghaiChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic MedicinePeking Union Medical CollegeBeijingChina Center of Excellence in Tissue Engineering Chinese Academy of Medical SciencesBeijingChina Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy BeijingChina

Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous *** droplet formation begins with the synthesis of neutral lipids in the endoplasmic ***,lipid droplets were recognized for their role in maintaining lipid metabolism and energy homeostasis;however,recent research has shown that lipid droplets are highly adaptive organelles with diverse functions in the nervous *** addition to their role in regulating cell metabolism,lipid droplets play a protective role in various cellular stress ***,lipid droplets exhibit specific functions in neurons and glial *** of lipid droplet formation leads to cellular dysfunction,metabolic abnormalities,and nervous system *** review aims to provide an overview of the role of lipid droplets in the nervous system,covering topics such as biogenesis,cellular specificity,and ***,it will explore the association between lipid droplets and neurodegenerative *** the involvement of lipid droplets in cell metabolic homeostasis related to the nervous system is crucial to determine the underlying causes and in exploring potential therapeutic approaches for these diseases.

关键词： Alzheimer's disease lipid droplet biogenesis lipid droplets lipid metabolism nervous system neurodegenerative disorders oxidative stress Parkinson's disease

Imperative for long-term management and surveillance in Kawasaki disease

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World Journal of Clinical Cases 2025年第4期13卷 61-63页

作者： Yan Pan Fu-Yong jiao Department of Pediatrics The First Affiliated Hospital of Yangtze UniversityJingzhou 434000Hubei ProvinceChina Shaanxi Kawasaki Disease Diagnosis and Treatment Center Children’s HospitalShaanxi Provincial People’s Hospital of Xi’an Jiaotong UniversityXi’an 710000Shaanxi ProvinceChina

Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery *** the effectiveness of initial treatments,such as intravenous immunoglobulin,KD patients can experience long-term cardiovascular issues,as evidenced by a recent case report of an adult who suffered a ST-segment elevation myocardial infarction due to previous KD in the World Journal of Clinical *** editorial emphasizes the critical need for long-term management and regular surveillance to prevent such *** drawing on recent research and case studies,we advocate for a structured approach to follow-up care that includes routine cardiac evaluations and preventive measures.

关键词： Kawasaki disease Long-term management Coronary artery aneurysm Surveillance Preventive care

CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ

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Cellular & Molecular Immunology 2021年第1期18卷 171-181页

作者： Ruo Chen Ke Wang Zhuan Feng Ming-Yang Zhang jiao Wu jie-jie Geng zhi-Nan Chen Department of Cell Biology College of Life Science and TechnologyJinan UniversityGuangdongChina National Translational Science Center for Molecular Medicine&Department of Cell Biology Fourth Military Medical UniversityShaanxiChina

Thymic involution during aging is a major cause of decreased T-cell production and reduced ***,we show that the loss of CD147 on T cells prevents thymic senescence,resulting in slowed shrinkage of the thymus with age and increased production of naive T *** phenotype is the result of slowing of the epithelial-mesenchymal transition(EMT)process in thymic epithelial cells(TECs),which eventually leads to reduced adipocyte *** an in vitro coculture system,we found that TGFβ is an important factor in the EMT process in TECs and that it can reduce the expression of E-cadherin through p-5mad2/FoxC2 ***,CD147 on T cells can accelerate the decline in E-cadherin expression by interacting with Annexin A2 on *** the presence of TGFβ,Annexin A2 and E-cadherin colocalize on ***,CD147 on T cells competitively binds to Annexin A2 on TECs,leading to the isolation of ***,the isolated E-cadherin is easily phosphorylated by phosphorylated Src kinase,the phosphorylation of which was induced by TGFβ,and finally,p-E-cadherin is ***,in the thymus,the interaction between T ceils and TECs contributes to thymic involution with *** this study,we illuminate the mechanism underlying the triggering of the EMT process in TECs and show that inhibiting TGFβ and/or CD147 may serve as a strategy to hinder age-related thymic involution.

关键词： CD147 TGFβ thymic involution EMT

Strain-magnetization property of Ni-Mn-Ga(Co,Cu) microwires

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Rare Metals 2023年第1期42卷 244-253页

作者： zhi-Yi Ding Jia-jie Gao Zeng-Bao jiao Hong-Hui Wu Ai-Ying Chen jie Zhu State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing100083China School of Materials Science and Chemistry University of Shanghai for Science and TechnologyShanghai200093China Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHong Kong999077China School of Materials Science and Engineering University of Science and Technology BeijingBeijing100083China

Magnetization associated with reversible phase transformation or rearrangement of martensite variants of two kinds of shape memory alloys under the coupling of tensile stress were *** is the austenitic Ni_(46)Mn_(28)Ga_(20)Co_(3)Cu_(3)micro wire with the [001] preferred orientation,which exhibits enhanced cyclic stability and large fully recoverable strain(> 8%) due to the stress-induced reversible martensitic transformation at room *** other is the Ni_(54)Mn_(24)Ga_(22)microwire with ferromagnetic martensitic phase,which has preferential orientation and also exhibits large tensile *** on the improved mechanical properties,the strain-magnetization effect of the two kinds of microwire under the coupling of orthogonal magnetic field and tensile stress was performed and the results indicate that the magnetization decreases with the increase of tensile ***,the magnetization mechanism related to the magnetostructural evolution under stress-magnetic coupling was *** study provides a new way for smart magnetic microwires for novel non-contact and non-destructive detection.

关键词： Ni-Mn-Ga Magnetic shape memory alloy Strain-magnetization effect Superelasticity Martensitic transformation