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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-Hui Zhang zhi-Lai Zhan Guang-Lu Chang Yan Gao xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

A Domain-Guided Model for Facial Cartoonlization

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IEEE/CAA Journal of Automatica Sinica 2022年第10期9卷 1886-1888页

作者： nan Yang Bingjie xia zhi Han Tianran Wang Shenyang Institute of Automation Chinese Academy of SciencesShenyang 110016 University of Chinese Academy of Sciences Beijing 100049China IEEE

Dear Editor,This work investigates the issue of facial cartoonlization under the condition of lacking training *** propose a domain-guided model(DGM)to realize facial cartoonlization for different kinds of *** includes two parts:1)a domain-guided model that contains four different interface networks and can embed an image from a facial domain to a cartoon domain independently;and 2)a one-to-one tutoring strategy that uses a sub-model as a teacher to train other interface networks and can yield fine-grained cartoon faces.

关键词： networks interface Domain

Reversible electrochemistry of DNA on multi-walled carbon nanotube modified electrode

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Chinese Chemical Letters 2007年第7期18卷 861-864页

作者： Hong xia Luo zhi Xin Guo nan He Department of Chemistry Renmin University of China Beijing 100872 China

Calf thymus DNA was electrochemically oxidized at a multi-walled carbon nanotube modified electrode. The potentials for DNA oxidation at pH 7.0 were 0.71 and 0.81 V versus SCE, corresponding to the oxidation of guanine and adenine residues,respectively. The initial 6e-oxidation of adenine, observed in the first scan, resulted a quasi-reversible 2e-redox process of the oxidation product in the following scans.

关键词： Carbon nanotube DNA Cyclic voltammetry Reversible

Purification and studies on characteristics of cholinesterases from Daphnia magna

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第4期14卷 325-335页

作者： Yan-xia YANG Li-zhi NIU Shao-nan LI Institute of Pesticide and Environmental Toxicology College of Agriculture and BiotechnologyZhejiang University

Due to their significant value in both economy and ecology,Daphnia had long been employed to investigate in vivo response of cholinesterase(ChE) in anticholinesterase exposures,whereas the type constitution and property of the enzyme remained unclear.A type of ChE was purified from Daphnia magna using a three-step procedure,i.e.,Triton X-100 extraction,ammonium sulfate precipitation,and diethylaminoethyl(DEAE)-Sepharose Fast-Flow *** to sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE),molecular mass of the purified ChE was estimated to be 84 *** on substrate studies,the purified enzyme preferred butyrylthiocholine iodide(BTCh) [with maximum velocity(Vmax)/Michaelis constant(Km)=8.428 L/(min·mg protein)] to acetylthiocholine iodide(ATCh) [with V max /Km =5.346 L/(min·mg protein)] as its *** of the purified enzyme was suppressed by high concentrations of either ATCh or *** studies showed that the purified enzyme was more sensitive towards inhibition by tetraisopropylpyrophosphoramide(iso-OMPA) than by 1,5-bis(4-allyldimethylammoniumphenyl) pentan-3-one dibromide(BW284C51).Result of the study suggested that the purified ChE was more like a type of pseudocholinesterase,and it also suggested that Daphnia magna contained multiple types of ChE in their bodies.

关键词： Crustacea Pseudocholinesterase Cholinesterase Substrate preference Selective inhibitors

Prospects on mangrove knowledge services in the smart era: From plant atlas to knowledge graphs

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Science China Earth Sciences 2025年第1期 111-127页

作者： zhi-Wei HOU Wenlong JING Cheng-zhi QIN Ji YANG Qing xia xiaoling YIN Key Laboratory of Guangdong for Utilization of Remote Sensing and Geographical Information System Guangdong Open Laboratory of Geospatial Information Technology and Application Guangzhou Institute of Geography Guangdong Academy of Sciences Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of Sciences College of Resources and Environment University of Chinese Academy of Sciences School of Traffic & Transportation Engineering Changsha University of Science and Technology

Mangroves are crucial to the ecological security of the Earth and human well-being. Their management, conservation, and restoration are of great importance and necessitate the support of spatio-temporal information and multidisciplinary knowledge such as biology and ecology. Traditional knowledge services such as plant atlas provide illustrated textual knowledge of mangroves. However, this kind of service is oriented to information retrieval and is incapable of effectively mining and utilizing fragmented knowledge from multi-source heterogeneous data, facing the problem of “massive data, rare knowledge”. Knowledge graphs are capable of extracting, organizing, and fusing the knowledge contained in massive data into semantic networks that can be understood and computed by computers. They provide a solution for the realization of intelligent knowledge services. Focusing on the urgent need for mangrove knowledge acquisition, formal representation, and intelligent services, this paper proposes a research prospect on mangrove knowledge graphs and knowledge services. We first analyze the similarities and differences between various domain-specific concepts of Tupu. On this basis, we define the mangrove knowledge graph as a large-scale knowledge base that integrates multi-disciplinary knowledge and spatio-temporal information with mangrove ecosystems as the core. Then, we propose a research framework for mangrove knowledge services that can realize the transformation from multi-modal data to intelligent knowledge services, including multiple research levels such as ubiquitous data sensing and aggregation, knowledge organization and graph construction, and intelligent mangrove knowledge services. Subsequently, the methods and workflow for constructing mangrove knowledge graphs are introduced. Finally, we discuss the challenges and possible future directions of mangrove knowledge services in the smart era, including the construction of a mangrove knowledge system that integra

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High thermal stability and blue-violet emitting phosphor CaYA1O4:Ti^4+with enhanced emission by Ca^2+vacancies

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Journal of Rare Earths 2020年第3期38卷 227-233页

作者： Mao xia Yongli Zhang Minghui Li Yuan Zhong Simin Gu nan Zhou zhi Zhou College of Science Hunan Agricultural UniversityChangsha 410128China Hunan Optical Agriculture Engineering Technology Research Center Changsha 410128China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China

Blue-violet light can not only enhance the total content of biomass and glucoside but also enrich the taste of the ***,it is meaningful to study the blue-violet luminescent materials for plant *** this study,titanium(IV)-activated CaYAlO4(CYAO) phosphors were synthesized by conventional hightemperature solid-state reaction.X-ray powder diffraction was employed to analyze the crystalstructure of *** is found that the doped Ti^4+ ions do not change obviously the crystal structure of *** 246 nm excitation,CaYAl1-xO4:xTi^4+phosphors exhibit broad blue-violet emission band peaking at 395 nm,which can be attributed to the charge transfer of Ti^4+-O^2-.Moreover,this phosphor exhibits strong thermal *** luminescence emission intensity at 150℃maintained about 91 mol% of its initial value at room ***,the electron transition process and concentration quenching mechanism of CaYAl1-xO4:xTi^4+are discussed in *** excellent luminescent properties indicate that CaYAl1-xO4:xTi^4+phosphor may have promising application in indoor plant cultivation.

关键词： Blue-violet-emitting Ca^2+ vacancies Phosphors Plant growth lighting Ti^4+-activated

Altered Expression of COMP,Collagen 1,and MMP9 in Pelvic Organ Prolapse

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Biomedical and Environmental Sciences 2023年第10期36卷 979-982页

作者： CHEN Yi Fei XU Hai nan DUAN Yi nan xia zhi Jun Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyang 110004LiaoningChina Department of Obstetrics and Gynecology Liaoning Province Hospital for Women and ChildrenShenyang 110004LiaoningChina Department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200090China

Female pelvic organ prolapse(POP)is a common disorder that affects the quality of life of women *** in China have reported a 9.6%prevalence of symptomatic POP in adult women[1],with a higher prevalence among older women.

关键词： Collagen MMP9 COMP POP

Parameter feature extraction for hyperspectral detection of the shallow underwater target

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Science China(Technological Sciences) 2021年第5期64卷 1092-1100页

作者： xia zhi GU YanFeng Acoustic Science and Technology Laboratory Harbin Engineering UniversityHarbin 150001China College of Underwater Acoustic Engineering Harbin Engineering UniversityHarbin 150001China School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin 150001China

For the detection of shallow underwater targets by the hyperspectrum, the information of the target is carried in the water-leaving radiation. However, the differences between the water-leaving radiation of the underwater target and the ocean background radiation are not significant, and the spectrum of the water-leaving radiation is sensitive to the changes of the marine environment. Therefore, taking the spectrum as the feature is not stable for hyperspectral detection of the underwater target. In this paper, we propose a parameter feature extraction method for hyperspectral detection of the shallow underwater target. The presence of an underwater target would change the optical properties of seawater in a local place. Based on that, a quasianalytical model of the water-leaving radiation is adopted to inverse the properties of the marine environment from the radiated spectrum. Then the inversed water depth and bottom reference reflectance are taken as the features. Simulation results show that the samples which belong to the water-leaving radiation of underwater target have higher inversed depth and reference reflectance than that belong to the ocean background radiation. Furthermore, these two kinds of samples can be separated significantly and stably in a 2-dimension feature space.

关键词： hyperspectral imaging underwater technology feature extraction

面向DAG任务的分布式智能计算卸载和服务缓存联合优化

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中山大学学报（自然科学版）（中英文） 2025年第1期64卷 71-82页

作者：李云南子煜姚枝秀夏士超鲜永菊重庆邮电大学通信与信息工程学院重庆400065 重庆邮电大学软件工程学院重庆400065

建立了一种有向无环图(DAG,directed acyclic graph)任务卸载和资源优化问题,旨在应用最大可容忍时延等约束实现系统能耗最小化。考虑到网络中计算请求高度动态、完整的系统状态信息难以获取等因素,最后使用多智能体深度确定性策略梯度(... 详细信息

建立了一种有向无环图(DAG,directed acyclic graph)任务卸载和资源优化问题,旨在应用最大可容忍时延等约束实现系统能耗最小化。考虑到网络中计算请求高度动态、完整的系统状态信息难以获取等因素,最后使用多智能体深度确定性策略梯度(MADDPG,multi-agent deep deterministic policy gradient)算法来探寻最优的策略。相比于现有的任务卸载算法,MADDPG算法能够降低14.2%至40.8%的系统平均能耗,并且本地缓存命中率提高3.7%至4.1%。

关键词：移动边缘计算多智能体深度强化学习计算卸载资源分配服务缓存